Ptbp2 (polypyrimidine tract binding protein 2) - Rat Genome Database

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Gene: Ptbp2 (polypyrimidine tract binding protein 2) Heterocephalus glaber
Analyze
Symbol: Ptbp2
Name: polypyrimidine tract binding protein 2
RGD ID: 18924730
Description: ENCODES a protein that exhibits mRNA binding (inferred); RNA binding (inferred); INVOLVED IN cerebellum development (ortholog); mRNA splice site recognition (ortholog); negative regulation of RNA splicing (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN growth cone (ortholog); neuronal cell body (ortholog); spliceosomal complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Polypyrimidine tract-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624742783,612 - 855,900 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624742783,612 - 856,039 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ptbp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624742783,612 - 855,900 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624742783,612 - 856,039 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PTBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38196,721,784 - 96,823,739 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl196,721,665 - 96,823,738 (+)EnsemblGRCh38hg38GRCh38
GRCh37197,187,340 - 97,289,295 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36196,959,966 - 97,052,937 (+)NCBINCBI36Build 36hg18NCBI36
Build 34196,899,398 - 96,992,367NCBI
Celera195,441,461 - 95,534,886 (+)NCBICelera
Cytogenetic Map1p21.3NCBI
HuRef195,308,506 - 95,401,741 (+)NCBIHuRef
CHM1_1197,303,210 - 97,396,589 (+)NCBICHM1_1
T2T-CHM13v2.0196,569,913 - 96,671,844 (+)NCBIT2T-CHM13v2.0
Ptbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393119,512,390 - 119,578,296 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3119,512,391 - 119,578,115 (-)EnsemblGRCm39 Ensembl
GRCm383119,718,741 - 119,784,647 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3119,718,742 - 119,784,466 (-)EnsemblGRCm38mm10GRCm38
MGSCv373119,421,660 - 119,486,306 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363119,710,998 - 119,775,262 (-)NCBIMGSCv36mm8
Celera3126,129,123 - 126,191,916 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map352.18NCBI
Ptbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82210,497,610 - 210,558,497 (-)NCBIGRCr8
mRatBN7.22207,812,659 - 207,874,019 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2207,812,920 - 207,873,506 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2215,463,900 - 215,523,276 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02213,387,983 - 213,447,341 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02208,213,458 - 208,272,785 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02223,261,444 - 223,323,075 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2223,262,852 - 223,322,585 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02241,306,857 - 241,368,189 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42216,188,745 - 216,249,176 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2200,269,277 - 200,328,535 (-)NCBICelera
Cytogenetic Map2q42NCBI
Ptbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554351,702,962 - 1,774,334 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554351,703,588 - 1,773,016 (+)NCBIChiLan1.0ChiLan1.0
PTBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21130,211,817 - 130,303,081 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11129,366,565 - 129,457,692 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,382,924 - 99,474,053 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1198,105,913 - 98,196,729 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl198,105,913 - 98,196,723 (+)Ensemblpanpan1.1panPan2
PTBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1652,870,944 - 52,948,673 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl652,872,310 - 52,949,025 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha655,556,557 - 55,640,856 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0653,223,659 - 53,275,783 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl653,223,576 - 53,303,282 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1652,917,509 - 52,995,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0652,896,678 - 52,974,367 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0653,342,619 - 53,426,749 (-)NCBIUU_Cfam_GSD_1.0
Ptbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058106,199,552 - 106,271,053 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365372,676,130 - 2,747,524 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365372,676,920 - 2,748,568 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4120,961,381 - 121,041,802 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14120,961,211 - 121,041,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24132,800,514 - 132,848,125 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12036,465,812 - 36,559,480 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2036,464,689 - 36,559,307 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603381,500,833 - 81,593,658 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000005733   ⟹   ENSHGLP00000005661
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624742783,612 - 855,900 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000005734   ⟹   ENSHGLP00000005662
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624742785,063 - 837,851 (-)Ensembl
RefSeq Acc Id: XM_004841216   ⟹   XP_004841273
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624742783,612 - 856,038 (-)NCBI
RefSeq Acc Id: XM_004841217   ⟹   XP_004841274
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624742783,612 - 856,036 (-)NCBI
RefSeq Acc Id: XM_004841218   ⟹   XP_004841275
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624742783,612 - 856,039 (-)NCBI
RefSeq Acc Id: XM_004841219   ⟹   XP_004841276
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624742783,612 - 856,037 (-)NCBI
RefSeq Acc Id: XM_013070869   ⟹   XP_012926323
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624742783,612 - 855,099 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004841275   ⟸   XM_004841218
- Peptide Label: isoform X1
- UniProtKB: G5BDN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841273   ⟸   XM_004841216
- Peptide Label: isoform X2
- UniProtKB: G5BDN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841276   ⟸   XM_004841219
- Peptide Label: isoform X3
- UniProtKB: G5BDN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841274   ⟸   XM_004841217
- Peptide Label: isoform X4
- UniProtKB: G5BDN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926323   ⟸   XM_013070869
- Peptide Label: isoform X5
- UniProtKB: G5BDN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000005661   ⟸   ENSHGLT00000005733
RefSeq Acc Id: ENSHGLP00000005662   ⟸   ENSHGLT00000005734


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004138 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005733 ENTREZGENE
  ENSHGLT00000005734 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro HnRNP-L/PTB UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PTBP1-like_RRM2 UniProtKB/TrEMBL
  PTBP2_RRM1 UniProtKB/TrEMBL
  PTBP2_RRM3 UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene Ptbp2 ENTREZGENE
PANTHER MATRIN 3/NUCLEAR PROTEIN 220-RELATED UniProtKB/TrEMBL
  POLYPYRIMIDINE TRACT-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
  RRM_5 UniProtKB/TrEMBL
  RRM_8 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP RNA-binding domain, RBD UniProtKB/TrEMBL
UniProt G5BDN9 ENTREZGENE, UniProtKB/TrEMBL