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Gene: Ptbp2 (polypyrimidine tract binding protein 2) Mus musculus
Symbol: Ptbp2
Name: polypyrimidine tract binding protein 2
Description: Exhibits mRNA binding activity. Involved in mRNA splice site selection and regulation of neural precursor cell proliferation. Localizes to the spliceosomal complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PTBP2 (polypyrimidine tract binding protein 2); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 17alpha-ethynylestradiol; 4-hydroxyphenyl retinamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-enriched polypyrimidine tract-binding protein; brain-enriched PTB; brPTB; neural polypyrimidine tract-binding protein; nPTB; polypyrimidine tract-binding protein 2; Ptb2; RRM-type RNA-binding protein brPTB
Homo sapiens (human) : PTBP2 (polypyrimidine tract binding protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptbp2 (polypyrimidine tract binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptbp2 (polypyrimidine tract binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTBP2 (polypyrimidine tract binding protein 2)
Canis lupus familiaris (dog) : PTBP2 (polypyrimidine tract binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptbp2 (polypyrimidine tract binding protein 2)
Sus scrofa (pig) : PTBP2 (polypyrimidine tract binding protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm383119,718,741 - 119,784,647 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373119,421,660 - 119,486,306 (-)NCBIGRCm37mm9NCBIm37
MGSCv363119,710,998 - 119,775,262 (-)NCBImm8
Celera3126,129,123 - 126,191,915 (-)NCBICelera
Cytogenetic Map3 G1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptbp2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550611
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.