Dctn2 (dynactin subunit 2) - Rat Genome Database

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Gene: Dctn2 (dynactin subunit 2) Heterocephalus glaber
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Symbol: Dctn2
Name: dynactin subunit 2
RGD ID: 18924001
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein kinase binding (ortholog); spectrin binding (ortholog); INVOLVED IN melanosome transport (ortholog); mitotic metaphase chromosome alignment (ortholog); mitotic spindle organization (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH cataract 15 multiple types (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease axonal type 2U (ortholog); FOUND IN centrosome (ortholog); dynactin complex (ortholog); growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480210,412,466 - 10,429,354 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dctn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480210,412,466 - 10,429,354 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DCTN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,530,051 - 57,547,192 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,529,633 - 57,547,224 (-)EnsemblGRCh38hg38GRCh38
GRCh371257,923,834 - 57,940,975 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,210,361 - 56,227,245 (-)NCBINCBI36Build 36hg18NCBI36
Build 341256,210,360 - 56,227,245NCBI
Celera1257,579,926 - 57,596,808 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,961,731 - 54,979,012 (-)NCBIHuRef
CHM1_11257,891,658 - 57,908,952 (-)NCBICHM1_1
T2T-CHM13v2.01257,498,291 - 57,515,431 (-)NCBIT2T-CHM13v2.0
Dctn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,102,131 - 127,117,828 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,102,237 - 127,117,819 (+)EnsemblGRCm39 Ensembl
GRCm3810127,266,262 - 127,281,959 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,266,368 - 127,281,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710126,703,318 - 126,719,015 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,669,348 - 126,684,756 (+)NCBIMGSCv36mm8
Celera10129,658,775 - 129,674,400 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Dctn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,977,338 - 64,992,875 (+)NCBIGRCr8
mRatBN7.2763,092,061 - 63,107,560 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,092,057 - 63,108,543 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,981,425 - 64,996,689 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,183,845 - 67,199,109 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,985,182 - 67,000,460 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,555,953 - 70,571,433 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,556,019 - 70,572,614 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,730,089 - 70,745,583 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,223,893 - 67,239,157 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,244,622 - 67,259,886 (+)NCBI
Celera760,232,682 - 60,247,954 (+)NCBICelera
Cytogenetic Map7q22NCBI
Dctn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,247,871 - 5,265,242 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,247,871 - 5,264,424 (-)NCBIChiLan1.0ChiLan1.0
DCTN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,793,760 - 36,810,798 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,790,531 - 36,807,569 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,379,531 - 31,396,570 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,638,272 - 31,655,458 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,636,884 - 31,655,458 (+)Ensemblpanpan1.1panPan2
DCTN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,620,702 - 1,634,385 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,620,724 - 1,634,309 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,683,865 - 1,697,555 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,629,967 - 1,643,711 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,630,053 - 1,643,684 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,607,705 - 1,621,392 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,849,593 - 1,863,307 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,974,591 - 1,988,304 (-)NCBIUU_Cfam_GSD_1.0
Dctn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,175,175 - 57,191,709 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,678,678 - 1,695,142 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,678,678 - 1,695,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCTN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,799,287 - 22,814,362 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,799,286 - 22,814,358 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DCTN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,438,878 - 53,456,181 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,439,249 - 53,456,267 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,507,976 - 192,525,286 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004861214   ⟹   XP_004861271
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,412,466 - 10,429,354 (+)NCBI
RefSeq Acc Id: XM_004861215   ⟹   XP_004861272
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,412,466 - 10,428,622 (+)NCBI
RefSeq Acc Id: XM_004861216   ⟹   XP_004861273
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,412,466 - 10,429,354 (+)NCBI
RefSeq Acc Id: XM_004861217   ⟹   XP_004861274
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,412,467 - 10,428,622 (+)NCBI
RefSeq Acc Id: XM_004861218   ⟹   XP_004861275
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,412,466 - 10,429,354 (+)NCBI
RefSeq Acc Id: XM_004861219   ⟹   XP_004861276
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,412,467 - 10,428,622 (+)NCBI
RefSeq Acc Id: XM_004861221   ⟹   XP_004861278
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,413,580 - 10,429,354 (+)NCBI
RefSeq Acc Id: XM_021241452   ⟹   XP_021097111
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480210,413,611 - 10,428,622 (+)NCBI
RefSeq Acc Id: XP_004861271   ⟸   XM_004861214
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PXZ4 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861273   ⟸   XM_004861216
- Peptide Label: isoform X4
- UniProtKB: A0AAX6PYX8 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861275   ⟸   XM_004861218
- Peptide Label: isoform X6
- UniProtKB: A0AAX6PVM1 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861272   ⟸   XM_004861215
- Peptide Label: isoform X3
- UniProtKB: A0AAX6PXV8 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861274   ⟸   XM_004861217
- Peptide Label: isoform X5
- UniProtKB: A0AAX6PYC5 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861276   ⟸   XM_004861219
- Peptide Label: isoform X7
- UniProtKB: A0AAX6PVQ7 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861278   ⟸   XM_004861221
- Peptide Label: isoform X8
- UniProtKB: A0AAX6PYS2 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097111   ⟸   XM_021241452
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RJY0 (UniProtKB/TrEMBL),   G5BED0 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013797 ENTREZGENE
Ensembl Transcript ENSHGLT00000019419 ENTREZGENE
InterPro Dynamitin UniProtKB/TrEMBL
NCBI Gene Dctn2 ENTREZGENE
PANTHER DYNACTIN SUBUNIT 2 UniProtKB/TrEMBL
  PTHR15346 UniProtKB/TrEMBL
Pfam Dynamitin UniProtKB/TrEMBL
UniProt A0AAX6PVM1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PVQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PXV8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PXZ4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PYC5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PYS2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PYX8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RJY0 ENTREZGENE, UniProtKB/TrEMBL
  G5BED0 ENTREZGENE, UniProtKB/TrEMBL