Brsk2 (BR serine/threonine kinase 2) - Rat Genome Database

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Gene: Brsk2 (BR serine/threonine kinase 2) Heterocephalus glaber
Analyze
Symbol: Brsk2
Name: BR serine/threonine kinase 2
RGD ID: 18923848
Description: ENCODES a protein that exhibits ATPase binding (ortholog); magnesium ion binding (ortholog); protein kinase binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); axonogenesis (ortholog); ERAD pathway (ortholog); ASSOCIATED WITH Beckwith-Wiedemann syndrome (ortholog); delta beta-thalassemia (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN centrosome (ortholog); distal axon (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase BRSK2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,296,120 - 21,334,040 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Brsk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,296,120 - 21,334,040 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BRSK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,389,934 - 1,462,689 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,389,899 - 1,462,689 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,411,164 - 1,483,919 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,367,705 - 1,439,908 (+)NCBINCBI36Build 36hg18NCBI36
Build 34111,367,704 - 1,439,902NCBI
Celera111,444,570 - 1,515,142 (+)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef111,221,716 - 1,271,938 (+)NCBIHuRef
CHM1_1111,410,344 - 1,482,831 (+)NCBICHM1_1
T2T-CHM13v2.0111,461,201 - 1,537,121 (+)NCBIT2T-CHM13v2.0
Brsk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,503,488 - 141,557,981 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,503,488 - 141,557,984 (+)EnsemblGRCm39 Ensembl
GRCm387141,949,751 - 142,004,244 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,949,751 - 142,004,247 (+)EnsemblGRCm38mm10GRCm38
MGSCv377149,135,656 - 149,190,149 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,759,141 - 141,813,634 (+)NCBIMGSCv36mm8
Celera7141,703,446 - 141,758,649 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.43NCBI
Brsk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81206,465,040 - 206,518,156 (+)NCBIGRCr8
mRatBN7.21197,035,505 - 197,088,624 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1197,035,633 - 197,088,092 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01214,918,757 - 214,940,883 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,927,172 - 214,947,624 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,828,575 - 221,862,789 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41202,083,095 - 202,133,268 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1194,692,139 - 194,712,878 (+)NCBICelera
Cytogenetic Map1q41NCBI
Brsk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547610,911,515 - 10,929,183 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547610,911,515 - 10,951,544 (-)NCBIChiLan1.0ChiLan1.0
BRSK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,807,992 - 3,878,526 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1113,020,624 - 3,089,422 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0111,424,873 - 1,495,630 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,473,129 - 1,521,339 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,473,129 - 1,521,339 (+)Ensemblpanpan1.1panPan2
BRSK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11845,666,489 - 45,688,950 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1845,628,970 - 45,689,494 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1844,240,212 - 44,299,980 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01846,310,123 - 46,369,953 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1846,309,789 - 46,369,799 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11845,758,085 - 45,817,901 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01845,339,202 - 45,398,979 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01846,084,435 - 46,144,294 (+)NCBIUU_Cfam_GSD_1.0
Brsk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049471,053,652 - 1,081,939 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936816307,250 - 334,785 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936816307,736 - 335,953 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRSK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2896,585 - 953,108 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12896,720 - 953,908 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103235498
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111,193,740 - 1,258,829 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11,193,808 - 1,258,433 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236667626,642 - 32,661 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000012102   ⟹   ENSHGLP00000011970
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476621,296,120 - 21,334,040 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000012103   ⟹   ENSHGLP00000011971
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476621,297,923 - 21,333,993 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000012104   ⟹   ENSHGLP00000011972
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476621,300,235 - 21,333,993 (-)Ensembl
RefSeq Acc Id: XM_004851620   ⟹   XP_004851677
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_004851621   ⟹   XP_004851678
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_004851624   ⟹   XP_004851681
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_004851625   ⟹   XP_004851682
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_004851626   ⟹   XP_004851683
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_013074687   ⟹   XP_012930141
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_021264002   ⟹   XP_021119661
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_021264004   ⟹   XP_021119663
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_021264005   ⟹   XP_021119664
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XM_021264006   ⟹   XP_021119665
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,333,992 (-)NCBI
RefSeq Acc Id: XR_002397247
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XR_002397248
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,298,012 - 21,334,054 (-)NCBI
RefSeq Acc Id: XR_002397249
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,298,050 - 21,334,054 (-)NCBI
RefSeq Acc Id: XR_002397250
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,296,115 - 21,334,054 (-)NCBI
RefSeq Acc Id: XP_004851683   ⟸   XM_004851626
- Peptide Label: isoform X10
- UniProtKB: A0AAX6PI52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851682   ⟸   XM_004851625
- Peptide Label: isoform X9
- UniProtKB: A0AAX6PHA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851678   ⟸   XM_004851621
- Peptide Label: isoform X4
- UniProtKB: A0AAX6PGT6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851677   ⟸   XM_004851620
- Peptide Label: isoform X3
- UniProtKB: A0AAX6PHX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851681   ⟸   XM_004851624
- Peptide Label: isoform X7
- UniProtKB: A0AAX6PHE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119664   ⟸   XM_021264005
- Peptide Label: isoform X6
- UniProtKB: A0AAX6TDP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012930141   ⟸   XM_013074687
- Peptide Label: isoform X2
- UniProtKB: A0AAX6R1C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119661   ⟸   XM_021264002
- Peptide Label: isoform X1
- UniProtKB: A0AAX6TH59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119663   ⟸   XM_021264004
- Peptide Label: isoform X5
- UniProtKB: A0AAX6TGJ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119665   ⟸   XM_021264006
- Peptide Label: isoform X8
- UniProtKB: A0AAX6TIP0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011972   ⟸   ENSHGLT00000012104
Ensembl Acc Id: ENSHGLP00000011970   ⟸   ENSHGLT00000012102
Ensembl Acc Id: ENSHGLP00000011971   ⟸   ENSHGLT00000012103


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008575 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000012102 ENTREZGENE
  ENSHGLT00000012103 ENTREZGENE
  ENSHGLT00000012104 ENTREZGENE
NCBI Gene Brsk2 ENTREZGENE
UniProt A0AAX6PGT6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PHA4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PHE9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PHX9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PI52 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R1C0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TDP9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TGJ6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TH59 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TIP0 ENTREZGENE, UniProtKB/TrEMBL