Brix1 (biogenesis of ribosomes BRX1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Brix1 (biogenesis of ribosomes BRX1) Heterocephalus glaber
Analyze
Symbol: Brix1
Name: biogenesis of ribosomes BRX1
RGD ID: 18922376
Description: ENCODES a protein that exhibits RNA binding (inferred); rRNA binding (inferred); INVOLVED IN ribosomal large subunit assembly (inferred); ribosome biogenesis (inferred); rRNA processing (inferred); ASSOCIATED WITH alpha-methylacyl-CoA racemase deficiency (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN chromosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Brix domain-containing protein 2; BRX1, biogenesis of ribosomes, homolog; ribosome biogenesis protein BRX1 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475919,982,513 - 19,994,637 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475919,982,612 - 19,994,621 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (ISO)
nucleolus  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Brix1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475919,982,513 - 19,994,637 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475919,982,612 - 19,994,621 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BRIX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38534,915,711 - 34,925,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl534,915,677 - 34,925,996 (+)EnsemblGRCh38hg38GRCh38
GRCh37534,915,816 - 34,926,101 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36534,951,577 - 34,961,544 (+)NCBINCBI36Build 36hg18NCBI36
Celera534,798,052 - 34,808,019 (+)NCBICelera
Cytogenetic Map5p13.2NCBI
HuRef534,864,475 - 34,874,444 (+)NCBIHuRef
CHM1_1534,918,180 - 34,928,149 (+)NCBICHM1_1
T2T-CHM13v2.0535,162,745 - 35,173,028 (+)NCBIT2T-CHM13v2.0
Brix1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391510,474,865 - 10,486,023 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1510,474,865 - 10,486,033 (-)EnsemblGRCm39 Ensembl
GRCm381510,474,779 - 10,485,937 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1510,474,779 - 10,485,947 (-)EnsemblGRCm38mm10GRCm38
MGSCv371510,404,534 - 10,415,692 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361510,420,906 - 10,430,632 (-)NCBIMGSCv36mm8
Celera1510,271,850 - 10,283,020 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map155.35NCBI
Brix1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8261,177,769 - 61,188,647 (-)NCBIGRCr8
mRatBN7.2259,450,608 - 59,461,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl259,450,614 - 59,461,495 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx266,558,326 - 66,569,203 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0264,679,856 - 64,690,733 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0259,681,217 - 59,692,094 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0260,450,547 - 60,461,425 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl260,450,374 - 60,461,458 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0284,212,803 - 84,223,681 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4259,826,894 - 59,837,772 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1259,755,126 - 59,766,005 (-)NCBI
Celera259,212,330 - 59,223,208 (+)NCBICelera
Cytogenetic Map2q16NCBI
Brix1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542620,042,274 - 20,051,606 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542620,042,274 - 20,051,606 (+)NCBIChiLan1.0ChiLan1.0
BRIX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2475,410,743 - 75,420,843 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1573,564,375 - 73,574,589 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0575,444,136 - 75,454,911 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1580,723,896 - 80,734,348 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl580,723,896 - 80,734,348 (-)Ensemblpanpan1.1panPan2
BRIX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1473,375,310 - 73,385,451 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl473,375,304 - 73,385,396 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha472,991,753 - 73,001,881 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0473,881,066 - 73,891,206 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl473,881,060 - 73,891,154 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1473,628,665 - 73,638,767 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0473,752,321 - 73,762,448 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0474,285,566 - 74,295,689 (-)NCBIUU_Cfam_GSD_1.0
Brix1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213224,751,432 - 224,760,886 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365186,610,623 - 6,620,383 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365186,610,623 - 6,620,369 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRIX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1620,512,280 - 20,522,181 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11620,512,281 - 20,520,579 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21621,414,147 - 21,422,488 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BRIX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1433,807,951 - 33,818,546 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl433,808,309 - 33,820,658 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607124,110,260 - 24,121,180 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000006337   ⟹   ENSHGLP00000006259
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475919,982,513 - 19,994,637 (-)Ensembl
RefSeq Acc Id: XM_004848643   ⟹   XP_004848700
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475919,982,612 - 19,994,621 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004848700 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB11453 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006259
GenBank Protein JAO02495 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004848700   ⟸   XM_004848643
- UniProtKB: A0A0P6JDN0 (UniProtKB/TrEMBL),   G5BQ92 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006259   ⟸   ENSHGLT00000006337


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004566 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006337 ENTREZGENE
Gene3D-CATH Probable brix-domain ribosomal biogenesis protein UniProtKB/TrEMBL
InterPro Brix UniProtKB/TrEMBL
  BRX1 UniProtKB/TrEMBL
KEGG Report hgl:101716372 UniProtKB/TrEMBL
NCBI Gene Brix1 ENTREZGENE
PANTHER PTHR13634 UniProtKB/TrEMBL
  RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG UniProtKB/TrEMBL
Pfam Brix UniProtKB/TrEMBL
PROSITE BRIX UniProtKB/TrEMBL
SMART Brix UniProtKB/TrEMBL
Superfamily-SCOP Class II aaRS ABD-related UniProtKB/TrEMBL
UniProt A0A0P6JDN0 ENTREZGENE, UniProtKB/TrEMBL
  G5BQ92 ENTREZGENE, UniProtKB/TrEMBL