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Gene: BRIX1 (biogenesis of ribosomes BRX1) Homo sapiens
Symbol: BRIX1
Name: biogenesis of ribosomes BRX1
Description: Exhibits RNA binding activity. Predicted to be involved in ribosomal large subunit assembly. Localizes to nucleolus and nucleoplasm; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BRIX; brix domain containing 2; brix domain-containing protein 2; BRX1, biogenesis of ribosomes; BRX1, biogenesis of ribosomes, homolog; BXDC2; FLJ11100; ribosome biogenesis protein BRX1 homolog
Mus musculus (house mouse) : Brix1 (BRX1, biogenesis of ribosomes)  MGI  Alliance
Rattus norvegicus (Norway rat) : Brix1 (biogenesis of ribosomes BRX1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brix1 (biogenesis of ribosomes BRX1)
Pan paniscus (bonobo/pygmy chimpanzee) : BRIX1 (biogenesis of ribosomes BRX1)
Canis lupus familiaris (dog) : BRIX1 (biogenesis of ribosomes BRX1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brix1 (biogenesis of ribosomes BRX1)
Sus scrofa (pig) : BRIX1 (biogenesis of ribosomes BRX1)
Chlorocebus sabaeus (African green monkey) : BRIX1 (biogenesis of ribosomes BRX1)
Heterocephalus glaber (naked mole-rat) : Brix1 (biogenesis of ribosomes BRX1)
more info ...
Related Pseudogenes: BRIX1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl534,915,677 - 34,925,996 (+)EnsemblGRCh38hg38GRCh38
GRCh38534,915,711 - 34,925,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37534,915,820 - 34,925,787 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36534,951,577 - 34,961,544 (+)NCBINCBI36hg18NCBI36
Celera534,798,052 - 34,808,019 (+)NCBI
Cytogenetic Map5p13.2NCBI
HuRef534,864,475 - 34,874,444 (+)NCBIHuRef
CHM1_1534,918,180 - 34,928,149 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BRIX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605358
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.