Mkx (mohawk homeobox) - Rat Genome Database

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Gene: Mkx (mohawk homeobox) Heterocephalus glaber
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Symbol: Mkx
Name: mohawk homeobox
RGD ID: 18922235
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); collagen fibril organization (ortholog); intratendonous ossification (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Heterotopic Ossification (ortholog); nonpapillary renal cell carcinoma (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Homeobox protein Mohawk
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248056,060,131 - 6,122,305 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248056,061,635 - 6,121,926 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl285,436,222 - 5,496,831 (-)Ensembl
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mkx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248056,060,131 - 6,122,305 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248056,061,635 - 6,121,926 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl285,436,222 - 5,496,831 (-)Ensembl
MKX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381027,672,874 - 27,745,819 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1027,672,874 - 27,746,394 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371027,961,803 - 28,034,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361028,001,809 - 28,074,753 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341028,001,811 - 28,074,753NCBI
Celera1027,725,254 - 27,798,252 (-)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1027,678,080 - 27,751,075 (-)NCBIHuRef
CHM1_11027,961,725 - 28,034,733 (-)NCBICHM1_1
T2T-CHM13v2.01027,703,607 - 27,776,565 (-)NCBIT2T-CHM13v2.0
Mkx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,934,966 - 7,004,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,931,133 - 7,005,516 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38186,934,966 - 7,004,779 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,934,518 - 7,004,780 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37186,934,964 - 7,004,777 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36186,934,998 - 7,004,754 (-)NCBIMGSCv36mm8
Celera186,980,394 - 7,049,750 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.53NCBI
Mkx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,772,113 - 59,851,160 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1759,773,570 - 59,850,345 (-)EnsemblGRCr8
mRatBN7.21755,077,073 - 55,156,877 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,077,540 - 55,156,124 (-)EnsemblmRatBN7.2
Dahl_SR_JrHsd1761,080,638 - 61,159,529 (-)NCBI
Lyon_Normotensive1760,514,251 - 60,593,138 (-)NCBI
Lyon_Hypertensive1758,099,951 - 58,178,761 (-)NCBI
F344_StmMcwi1759,167,005 - 59,245,949 (-)NCBI
Rnor_6.01760,537,615 - 60,553,284 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,537,935 - 60,549,750 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01762,321,329 - 62,332,471 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41763,631,540 - 63,710,138 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1756,416,753 - 56,495,058 (-)NCBICelera
RGSC_v3.11763,642,477 - 63,722,172 (-)NCBI
Cytogenetic Map17q12.1NCBI
Mkx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,564,191 - 1,631,951 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554621,564,739 - 1,631,613 (-)NCBIChiLan1.0ChiLan1.0
MKX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2840,340,819 - 40,420,027 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11040,346,145 - 40,420,917 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01027,820,454 - 27,893,373 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11028,181,483 - 28,254,311 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1028,181,483 - 28,254,311 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
LOC487079
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.125,898,155 - 5,964,577 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha24,371,377 - 4,437,081 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.024,651,755 - 4,720,172 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UNSW_CanFamBas_1.0216,010,859 - 16,077,012 (+)NCBIUNSW_CanFamBas_1.0
Mkx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap11095,981,506 - 96,045,811 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_0244093447,469,239 - 7,533,485 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366132,019,783 - 2,084,267 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366132,019,815 - 2,083,724 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MKX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1039,096,782 - 39,172,198 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11039,096,778 - 39,173,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21053,679,406 - 53,744,157 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MKX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1927,536,772 - 27,615,427 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366605133,247,101 - 33,322,551 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1927,228,061 - 27,305,852 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Mkx
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11428,896,083 - 28,968,728 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000006506   ⟹   ENSHGLP00000006425
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248056,061,635 - 6,121,926 (-)Ensembl
Naked mole-rat maternal Ensembl285,436,222 - 5,496,831 (-)Ensembl
RefSeq Acc Id: XM_004861836   ⟹   XP_004861893
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248056,060,131 - 6,122,171 (-)NCBI
RefSeq Acc Id: XM_004861837   ⟹   XP_004861894
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248056,060,131 - 6,122,173 (-)NCBI
RefSeq Acc Id: XM_021242012   ⟹   XP_021097671
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248056,060,131 - 6,121,399 (-)NCBI
RefSeq Acc Id: XM_021242013   ⟹   XP_021097672
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248056,060,131 - 6,122,305 (-)NCBI
RefSeq Acc Id: XM_021242014   ⟹   XP_021097673
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248056,105,259 - 6,122,174 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004861893 (Get FASTA)   NCBI Sequence Viewer  
  XP_004861894 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097671 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097672 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097673 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15257 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006425
RefSeq Acc Id: XP_021097672   ⟸   XM_021242013
- Peptide Label: isoform X1
- UniProtKB: A0AAX6PWH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861894   ⟸   XM_004861837
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PWG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004861893   ⟸   XM_004861836
- Peptide Label: isoform X1
- UniProtKB: A0AAX6PWH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097671   ⟸   XM_021242012
- Peptide Label: isoform X1
- UniProtKB: A0AAX6PWH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097673   ⟸   XM_021242014
- Peptide Label: isoform X3
- UniProtKB: A0AAX6RMX4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006425   ⟸   ENSHGLT00000006506


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004695 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006506 ENTREZGENE
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
KEGG Report hgl:101698701 UniProtKB/TrEMBL
NCBI Gene Mkx ENTREZGENE
PANTHER HOMEOBOX PROTEIN MOHAWK UniProtKB/TrEMBL
  IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain-like UniProtKB/TrEMBL
UniProt A0AAX6PWG6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PWH4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RMX4 ENTREZGENE, UniProtKB/TrEMBL