Cldn15 (claudin 15) - Rat Genome Database

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Gene: Cldn15 (claudin 15) Heterocephalus glaber
Analyze
Symbol: Cldn15
Name: claudin 15
RGD ID: 18915651
Description: ENCODES a protein that exhibits paracellular tight junction channel activity (inferred); structural molecule activity (inferred); INVOLVED IN paracellular transport (inferred); regulation of intestinal D-glucose absorption (inferred); regulation of intestinal lipid absorption (inferred); ASSOCIATED WITH malignant mesothelioma (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN anchoring junction (inferred); bicellular tight junction (inferred); lateral plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Claudin-15
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,057,712 - 16,063,264 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,056,823 - 16,063,250 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cldn15Naked Mole-Ratpleomorphic xanthoastrocytoma  ISORGD:13217208554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cldn15Naked Mole-Ratmalignant mesothelioma  ISORGD:13217209068941CTD Direct Evidence: marker/mechanismCTDPMID:28377727


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cldn15Naked Mole-Ratparacellular transport involved_inIEAUniProtKB:P56746|UniProtKB:Q9Z0S5|ensembl:ENSMUSP00000106722|ensembl:ENSP00000308870150520179 EnsemblGO_REF:0000107
Cldn15Naked Mole-Ratregulation of intestinal D-glucose absorption involved_inIEAUniProtKB:Q9Z0S5|ensembl:ENSMUSP00000106722150520179 EnsemblGO_REF:0000107
Cldn15Naked Mole-Ratregulation of intestinal lipid absorption involved_inIEAUniProtKB:Q9Z0S5|ensembl:ENSMUSP00000106722150520179 EnsemblGO_REF:0000107

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cldn15Naked Mole-Ratanchoring junction located_inIEAUniProtKB-KW:KW-0965150520179 UniProtGO_REF:0000043
Cldn15Naked Mole-Ratbicellular tight junction located_inIEAUniProtKB-KW:KW-0796150520179 UniProtGO_REF:0000043
Cldn15Naked Mole-Ratbicellular tight junction located_inIEAUniRule:UR000060637150520179 UniProtGO_REF:0000104
Cldn15Naked Mole-Ratbicellular tight junction located_inIEAInterPro:IPR006187|InterPro:IPR008094150520179 InterProGO_REF:0000002
Cldn15Naked Mole-Ratbicellular tight junction located_inIEAUniProtKB-SubCell:SL-0265150520179 UniProtGO_REF:0000044
Cldn15Naked Mole-Ratlateral plasma membrane located_inIEAUniProtKB:Q9Z0S5|ensembl:ENSMUSP00000106722150520179 EnsemblGO_REF:0000107
Cldn15Naked Mole-Ratmembrane located_inIEAUniRule:UR000060637150520179 UniProtGO_REF:0000104
Cldn15Naked Mole-Ratmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
Cldn15Naked Mole-Ratmembrane located_inIEAInterPro:IPR004031150520179 InterProGO_REF:0000002
Cldn15Naked Mole-Ratplasma membrane located_inIEAUniProtKB-KW:KW-1003150520179 UniProtGO_REF:0000043
Cldn15Naked Mole-Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-0039150520179 UniProtGO_REF:0000044
Cldn15Naked Mole-Rattight junction located_inIEAUniProtKB:P56746|UniProtKB:Q9Z0S5|ensembl:ENSMUSP00000106722|ensembl:ENSP00000308870150520179 EnsemblGO_REF:0000107
1 to 12 of 12 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cldn15Naked Mole-Ratparacellular tight junction channel activity enablesIEAUniProtKB:P56746|ensembl:ENSP00000308870150520179 EnsemblGO_REF:0000107
Cldn15Naked Mole-Ratprotein binding enablesISOUniProtKB:Q8IY26|UniProtKB:Q8TB619068941 PMID:32296183IntActPMID:32296183
Cldn15Naked Mole-Ratstructural molecule activity enablesIEAInterPro:IPR006187|InterPro:IPR008094150520179 InterProGO_REF:0000002

PMID:21993625   PMID:22301074   PMID:30032202  



Cldn15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,057,712 - 16,063,264 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,056,823 - 16,063,250 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CLDN15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387101,232,094 - 101,238,820 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7101,232,092 - 101,238,820 (-)EnsemblGRCh38hg38GRCh38
GRCh377100,875,375 - 100,882,101 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,662,094 - 100,667,836 (-)NCBINCBI36Build 36hg18NCBI36
Build 347100,470,513 - 100,474,466NCBI
Celera795,884,531 - 95,891,259 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef795,468,416 - 95,475,144 (-)NCBIHuRef
CHM1_17100,805,777 - 100,812,511 (-)NCBICHM1_1
T2T-CHM13v2.07102,555,557 - 102,562,283 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27100,233,760 - 100,240,488 (-)NCBI
Cldn15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395136,996,723 - 137,004,699 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5136,995,470 - 137,004,712 (+)EnsemblGRCm39 Ensembl
GRCm385136,967,869 - 136,975,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5136,966,616 - 136,975,858 (+)EnsemblGRCm38mm10GRCm38
MGSCv375137,443,739 - 137,451,710 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365137,252,496 - 137,260,467 (+)NCBIMGSCv36mm8
Celera5133,983,919 - 133,991,861 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.07NCBI
Cldn15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81225,334,849 - 25,345,104 (-)NCBIGRCr8
mRatBN7.21219,698,167 - 19,708,419 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,698,337 - 19,706,819 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,837,753 - 20,845,310 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,450,458 - 21,458,015 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01220,515,654 - 20,523,070 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,738,198 - 22,750,392 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,738,195 - 22,748,860 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,749,982 - 24,759,973 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,823,334 - 20,845,306 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11220,813,183 - 20,833,795 (+)NCBI
Celera1221,475,263 - 21,482,160 (-)NCBICelera
Cytogenetic Map12q12NCBI
Cldn15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545616,062,046 - 16,069,540 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545616,062,044 - 16,067,612 (+)NCBIChiLan1.0ChiLan1.0
CLDN15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26119,245,327 - 119,252,795 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17167,509,956 - 167,517,417 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0793,373,450 - 93,380,912 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,613,604 - 106,620,479 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,613,604 - 106,620,479 (-)Ensemblpanpan1.1panPan2
CLDN15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.168,647,372 - 8,651,869 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,647,712 - 8,652,650 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,343,322 - 10,350,444 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.068,465,464 - 8,472,596 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl68,467,446 - 8,472,412 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,421,233 - 8,428,357 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,396,279 - 8,403,428 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.068,560,953 - 8,568,037 (+)NCBIUU_Cfam_GSD_1.0
Cldn15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344132,923,926 - 132,929,684 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365431,106,635 - 1,111,140 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365431,106,846 - 1,112,669 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLDN15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,931,097 - 8,937,184 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,931,099 - 8,937,189 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CLDN15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12811,940,318 - 11,947,811 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2811,942,271 - 11,947,627 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660704,405,099 - 4,412,551 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.






Ensembl Acc Id: ENSHGLT00000021488   ⟹   ENSHGLP00000021282
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474016,057,712 - 16,063,264 (+)Ensembl
RefSeq Acc Id: XM_004840143   ⟹   XP_004840200
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474016,057,658 - 16,063,250 (+)NCBI
RefSeq Acc Id: XM_021254474   ⟹   XP_021110133
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474016,056,823 - 16,063,250 (+)NCBI
Protein RefSeqs XP_004840200 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110133 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB01680 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021282
GenBank Protein JAN96245 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021110133   ⟸   XM_021254474
- UniProtKB: G5AXB8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840200   ⟸   XM_004840143
- UniProtKB: G5AXB8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000021282   ⟸   ENSHGLT00000021488



1 to 15 of 15 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000015207 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000021488 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro Claudin UniProtKB/TrEMBL
  Claudin15 UniProtKB/TrEMBL
  Claudin_CS UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
KEGG Report hgl:101700714 UniProtKB/TrEMBL
NCBI Gene Cldn15 ENTREZGENE
PANTHER PTHR12002 UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/TrEMBL
PRINTS CLAUDIN UniProtKB/TrEMBL
  CLAUDIN15 UniProtKB/TrEMBL
PROSITE CLAUDIN UniProtKB/TrEMBL
UniProt G5AXB8 ENTREZGENE, UniProtKB/TrEMBL
1 to 15 of 15 rows