Ubash3b (ubiquitin associated and SH3 domain containing B) - Rat Genome Database

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Gene: Ubash3b (ubiquitin associated and SH3 domain containing B) Heterocephalus glaber
Analyze
Symbol: Ubash3b
Name: ubiquitin associated and SH3 domain containing B
RGD ID: 18914630
Description: ENCODES a protein that exhibits identical protein binding (ortholog); phosphoprotein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN collagen-activated signaling pathway (ortholog); collagen-activated tyrosine kinase receptor signaling pathway (ortholog); negative regulation of bone resorption (ortholog); ASSOCIATED WITH chromosome 11 partial duplication syndrome (ortholog); Dwarfism (ortholog); schizophrenia (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin-associated and SH3 domain-containing protein B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248802,270,679 - 2,427,298 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248802,269,247 - 2,427,531 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ubash3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248802,270,679 - 2,427,298 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248802,269,247 - 2,427,531 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
UBASH3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811122,655,722 - 122,814,473 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11122,655,722 - 122,814,473 (+)EnsemblGRCh38hg38GRCh38
GRCh3711122,526,430 - 122,685,181 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611122,031,640 - 122,190,391 (+)NCBINCBI36Build 36hg18NCBI36
Celera11119,685,695 - 119,844,497 (+)NCBICelera
Cytogenetic Map11q24.1NCBI
HuRef11118,468,875 - 118,627,622 (+)NCBIHuRef
CHM1_111122,412,295 - 122,571,102 (+)NCBICHM1_1
T2T-CHM13v2.011122,683,359 - 122,842,181 (+)NCBIT2T-CHM13v2.0
Ubash3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39940,922,056 - 41,069,358 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl940,922,394 - 41,072,993 (-)EnsemblGRCm39 Ensembl
GRCm38941,010,760 - 41,161,692 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl941,011,098 - 41,161,697 (-)EnsemblGRCm38mm10GRCm38
MGSCv37940,821,724 - 40,965,577 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36940,764,710 - 40,908,563 (-)NCBIMGSCv36mm8
MGSCv36941,219,202 - 41,364,403 (-)NCBIMGSCv36mm8
Celera938,241,137 - 38,383,815 (-)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map921.84NCBI
Ubash3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8850,282,510 - 50,430,034 (-)NCBIGRCr8
mRatBN7.2841,385,419 - 41,532,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl841,388,341 - 41,532,201 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx846,882,006 - 47,025,074 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0845,160,614 - 45,303,702 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0843,028,175 - 43,171,244 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0845,224,053 - 45,375,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl845,223,992 - 45,375,435 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0843,702,541 - 43,853,864 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4843,992,862 - 44,135,847 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1844,001,003 - 44,067,551 (-)NCBI
Celera840,986,547 - 41,129,756 (-)NCBICelera
Cytogenetic Map8q22NCBI
Ubash3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541223,518,240 - 23,667,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541223,518,851 - 23,667,617 (+)NCBIChiLan1.0ChiLan1.0
UBASH3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29123,357,571 - 123,515,784 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111124,462,174 - 124,620,547 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011117,489,411 - 117,647,719 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111121,410,178 - 121,567,716 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11121,410,545 - 121,563,133 (+)Ensemblpanpan1.1panPan2
UBASH3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1511,496,254 - 11,614,769 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl511,500,669 - 11,614,675 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha511,551,610 - 11,690,824 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0511,446,452 - 11,586,409 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl511,447,895 - 11,586,395 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1511,549,978 - 11,689,276 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0511,488,972 - 11,628,138 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0511,527,189 - 11,666,755 (-)NCBIUU_Cfam_GSD_1.0
Ubash3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947104,304,260 - 104,451,965 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365427,225,977 - 7,373,381 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365427,225,387 - 7,370,163 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBASH3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl949,630,793 - 49,770,897 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1949,630,678 - 49,772,348 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2954,975,101 - 55,118,054 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBASH3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,053,792 - 114,218,909 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,054,384 - 114,218,912 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604311,913,397 - 12,072,484 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000001502   ⟹   ENSHGLP00000001458
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248802,270,679 - 2,303,366 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000001503   ⟹   ENSHGLP00000001459
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248802,271,162 - 2,427,298 (-)Ensembl
RefSeq Acc Id: XM_004870908   ⟹   XP_004870965
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248802,269,247 - 2,303,361 (-)NCBI
RefSeq Acc Id: XM_004870909   ⟹   XP_004870966
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248802,269,247 - 2,427,531 (-)NCBI
RefSeq Acc Id: XM_021249040   ⟹   XP_021104699
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248802,269,247 - 2,303,363 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004870965 (Get FASTA)   NCBI Sequence Viewer  
  XP_004870966 (Get FASTA)   NCBI Sequence Viewer  
  XP_021104699 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001459
RefSeq Acc Id: XP_004870966   ⟸   XM_004870909
- Peptide Label: isoform X3
- UniProtKB: G5BRZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021104699   ⟸   XM_021249040
- Peptide Label: isoform X2
- UniProtKB: G5BRZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004870965   ⟸   XM_004870908
- Peptide Label: isoform X1
- UniProtKB: G5BRZ8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000001458   ⟸   ENSHGLT00000001502
Ensembl Acc Id: ENSHGLP00000001459   ⟸   ENSHGLT00000001503


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001126 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001503 ENTREZGENE
Gene3D-CATH Cyclic phosphodiesterase UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Phosphoglycerate mutase-like UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro His_Pase_superF_clade-1 UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/TrEMBL
  Phosphatase_SH3-domain UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  UBASH3B_SH3 UniProtKB/TrEMBL
NCBI Gene Ubash3b ENTREZGENE
PANTHER UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UniProtKB/TrEMBL
  UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING PROTEIN B UniProtKB/TrEMBL
Pfam His_Phos_1 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
Superfamily-SCOP Phosphoglycerate mutase-like UniProtKB/TrEMBL
  SH3-domain UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
UniProt G5BRZ8 ENTREZGENE, UniProtKB/TrEMBL