Siva1 (SIVA1 apoptosis inducing factor) - Rat Genome Database

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Gene: Siva1 (SIVA1 apoptosis inducing factor) Heterocephalus glaber
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Symbol: Siva1
Name: SIVA1 apoptosis inducing factor
RGD ID: 18912282
Description: ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN activation-induced cell death of T cells (ortholog); intrinsic apoptotic signaling pathway (ortholog); negative regulation of NF-kappaB transcription factor activity (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease axonal type 2O (ortholog); Coxsackievirus Infections (ortholog); focal segmental glomerulosclerosis 5 (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Apoptosis regulatory protein Siva
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624734530,711 - 535,281 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Siva1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624734530,711 - 535,281 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SIVA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814104,753,147 - 104,759,654 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14104,753,147 - 104,768,494 (+)EnsemblGRCh38hg38GRCh38
GRCh3714105,219,484 - 105,225,991 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,290,515 - 104,297,041 (+)NCBINCBI36Build 36hg18NCBI36
Celera1485,274,542 - 85,281,070 (+)NCBICelera
Cytogenetic Map14q32.33NCBI
HuRef1485,416,458 - 85,422,986 (+)NCBIHuRef
CHM1_114105,157,086 - 105,163,614 (+)NCBICHM1_1
T2T-CHM13v2.01498,996,033 - 99,002,540 (+)NCBIT2T-CHM13v2.0
Siva1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912112,611,262 - 112,615,586 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12112,611,113 - 112,615,583 (+)EnsemblGRCm39 Ensembl
GRCm3812112,644,828 - 112,649,152 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12112,644,679 - 112,649,149 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712113,883,039 - 113,887,363 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612113,092,716 - 113,096,953 (+)NCBIMGSCv36mm8
Celera12113,858,455 - 113,862,779 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.2NCBI
Siva1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86137,526,416 - 137,530,790 (+)NCBIGRCr8
mRatBN7.26131,705,323 - 131,709,697 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6131,705,323 - 131,709,690 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6131,874,637 - 131,879,016 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06132,171,743 - 132,176,118 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06131,534,212 - 131,538,589 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06137,209,999 - 137,214,379 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6137,210,052 - 137,214,388 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06146,216,931 - 146,221,556 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46137,631,408 - 137,635,724 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6129,253,021 - 129,257,273 (+)NCBICelera
Cytogenetic Map6q32NCBI
Siva1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555383,197,983 - 3,202,782 (+)NCBIChiLan1.0ChiLan1.0
SIVA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215105,935,284 - 105,941,823 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114105,151,787 - 105,158,327 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01485,404,148 - 85,408,254 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114105,196,118 - 105,202,678 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14105,196,118 - 105,202,678 (+)Ensemblpanpan1.1panPan2
SIVA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1872,309,400 - 72,313,726 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl872,309,447 - 72,313,640 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha871,815,163 - 71,819,494 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0872,584,386 - 72,588,709 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl872,583,252 - 72,588,623 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1872,267,010 - 72,271,332 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0872,310,264 - 72,314,586 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0872,709,843 - 72,714,165 (+)NCBIUU_Cfam_GSD_1.0
Siva1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086401,812,507 - 1,821,101 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936621644,852 - 650,132 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936621641,456 - 650,067 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIVA1
(Sus scrofa - pig)		 No map positions available.
SIVA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12482,689,233 - 82,695,073 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2482,689,254 - 82,695,146 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605370,110,198 - 70,116,322 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004836853   ⟹   XP_004836910
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624734530,711 - 535,271 (-)NCBI
RefSeq Acc Id: XM_004836854   ⟹   XP_004836911
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624734530,711 - 535,281 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004836910 (Get FASTA)   NCBI Sequence Viewer  
  XP_004836911 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB01397 (Get FASTA)   NCBI Sequence Viewer  
  JAO02990 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004836911   ⟸   XM_004836854
- Peptide Label: isoform X2
- UniProtKB: A0AAX6NU51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836910   ⟸   XM_004836853
- Peptide Label: isoform X1
- UniProtKB: G5AWI6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
InterPro Siva UniProtKB/TrEMBL
KEGG Report hgl:101701551 UniProtKB/TrEMBL
NCBI Gene Siva1 ENTREZGENE
PANTHER APOPTOSIS REGULATORY PROTEIN SIVA UniProtKB/TrEMBL
  PTHR14365 UniProtKB/TrEMBL
Pfam Siva UniProtKB/TrEMBL
PIRSF Siva_cd27_bd UniProtKB/TrEMBL
UniProt A0AAX6NU51 ENTREZGENE, UniProtKB/TrEMBL
  G5AWI6 ENTREZGENE, UniProtKB/TrEMBL