Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2) - Rat Genome Database

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Gene: Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2) Heterocephalus glaber
Analyze
Symbol: Ndufs2
Name: NADH:ubiquinone oxidoreductase core subunit S2
RGD ID: 18909496
Description: ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); oxygen sensor activity (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); gliogenesis (ortholog); mitochondrial ATP synthesis coupled electron transport (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); cardiomyopathy (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN mitochondrial inner membrane (ortholog); nucleoplasm (ortholog); respiratory chain complex I (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794172,707 - 185,073 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794172,543 - 189,031 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ndufs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794172,707 - 185,073 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794172,543 - 189,031 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NDUFS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,197,417 - 161,214,395 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,197,104 - 161,214,723 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,167,207 - 161,184,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,435,729 - 159,450,809 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,982,177 - 157,997,255NCBI
Celera1134,236,257 - 134,251,337 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,526,050 - 132,541,132 (+)NCBIHuRef
CHM1_11162,565,343 - 162,580,438 (+)NCBICHM1_1
T2T-CHM13v2.01160,334,507 - 160,351,847 (+)NCBIT2T-CHM13v2.0
Ndufs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,062,426 - 171,078,956 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,062,422 - 171,078,957 (-)EnsemblGRCm39 Ensembl
GRCm381171,234,853 - 171,251,686 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,234,853 - 171,251,388 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,164,991 - 173,177,243 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,071,535 - 173,083,787 (-)NCBIMGSCv36mm8
Celera1173,691,078 - 173,703,327 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.25NCBI
Ndufs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,186,867 - 86,203,914 (-)NCBIGRCr8
mRatBN7.21383,654,402 - 83,671,474 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,654,406 - 83,671,420 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,160,251 - 86,172,822 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,558,491 - 87,571,027 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,790,115 - 84,802,527 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,606,848 - 89,623,506 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,606,840 - 89,619,398 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,769,663 - 95,770,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01394,233,713 - 94,250,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,124,431 - 87,137,497 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,313,317 - 87,326,381 (-)NCBI
Celera1383,285,589 - 83,298,039 (-)NCBICelera
Cytogenetic Map13q24NCBI
Ndufs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,961,915 - 12,971,095 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,961,873 - 12,971,278 (+)NCBIChiLan1.0ChiLan1.0
NDUFS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,637,595 - 88,654,983 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,327,913 - 88,341,098 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,609,822 - 136,626,851 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,526,690 - 140,538,705 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,526,690 - 140,538,705 (+)Ensemblpanpan1.1panPan2
NDUFS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,271,603 - 21,281,140 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,271,675 - 21,285,279 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,346,459 - 21,356,011 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,389,447 - 21,399,000 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,389,447 - 21,398,979 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,285,733 - 21,286,858 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,691,735 - 21,701,283 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,100,884 - 22,110,441 (-)NCBIUU_Cfam_GSD_1.0
Ndufs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,294,911 - 7,305,582 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903499,300 - 514,893 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903503,633 - 514,235 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,246,960 - 89,257,085 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,246,958 - 89,257,090 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,103,640 - 97,113,761 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,767,864 - 2,780,336 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,768,064 - 2,780,704 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,816,231 - 1,830,038 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000019171   ⟹   ENSHGLP00000018982
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624794172,707 - 185,073 (-)Ensembl
RefSeq Acc Id: XM_004858662   ⟹   XP_004858719
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624794172,543 - 189,031 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004858719 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB13641 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018982
  ENSHGLP00100044328
RefSeq Acc Id: XP_004858719   ⟸   XM_004858662
- UniProtKB: G5BWI0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018982   ⟸   ENSHGLT00000019171


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013603 Ensembl, ENTREZGENE
  ENSHGLG00100005459 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000019171 ENTREZGENE
  ENSHGLT00100052860 UniProtKB/TrEMBL
Gene3D-CATH 1.10.645.10 UniProtKB/TrEMBL
InterPro NADH_Q_OxRdtase_suD UniProtKB/TrEMBL
  NADH_UbQ_OxRdtase_49kDa_CS UniProtKB/TrEMBL
  NDH1_su_D/H UniProtKB/TrEMBL
  NiFe-Hase_large UniProtKB/TrEMBL
KEGG Report hgl:101701670 UniProtKB/TrEMBL
NCBI Gene Ndufs2 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR11993 UniProtKB/TrEMBL
Pfam Complex1_49kDa UniProtKB/TrEMBL
PROSITE COMPLEX1_49K UniProtKB/TrEMBL
Superfamily-SCOP SSF56762 UniProtKB/TrEMBL
UniProt G5BWI0 ENTREZGENE, UniProtKB/TrEMBL