Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2) - Rat Genome Database

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Gene: Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2) Chinchilla lanigera
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Symbol: Ndufs2
Name: NADH:ubiquinone oxidoreductase core subunit S2
RGD ID: 8706442
Description: ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); oxygen sensor activity (ortholog); INVOLVED IN cellular response to oxygen levels (ortholog); gliogenesis (ortholog); mitochondrial ATP synthesis coupled electron transport (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); cardiomyopathy (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,961,915 - 12,971,095 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,961,873 - 12,971,278 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ndufs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,961,915 - 12,971,095 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,961,873 - 12,971,278 (+)NCBIChiLan1.0ChiLan1.0
NDUFS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,197,417 - 161,214,395 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,197,104 - 161,214,723 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,167,207 - 161,184,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,435,729 - 159,450,809 (+)NCBINCBI36Build 36hg18NCBI36
Build 341157,982,177 - 157,997,255NCBI
Celera1134,236,257 - 134,251,337 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,526,050 - 132,541,132 (+)NCBIHuRef
CHM1_11162,565,343 - 162,580,438 (+)NCBICHM1_1
T2T-CHM13v2.01160,334,507 - 160,351,847 (+)NCBIT2T-CHM13v2.0
Ndufs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,062,426 - 171,078,956 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,062,422 - 171,078,957 (-)EnsemblGRCm39 Ensembl
GRCm381171,234,853 - 171,251,686 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,234,853 - 171,251,388 (-)EnsemblGRCm38mm10GRCm38
MGSCv371173,164,991 - 173,177,243 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,071,535 - 173,083,787 (-)NCBIMGSCv36mm8
Celera1173,691,078 - 173,703,327 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.25NCBI
Ndufs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,186,867 - 86,203,914 (-)NCBIGRCr8
mRatBN7.21383,654,402 - 83,671,474 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,654,406 - 83,671,420 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,160,251 - 86,172,822 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,558,491 - 87,571,027 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,790,115 - 84,802,527 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,606,848 - 89,623,506 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,606,840 - 89,619,398 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,769,663 - 95,770,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01394,233,713 - 94,250,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,124,431 - 87,137,497 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,313,317 - 87,326,381 (-)NCBI
Celera1383,285,589 - 83,298,039 (-)NCBICelera
Cytogenetic Map13q24NCBI
NDUFS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,637,595 - 88,654,983 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,327,913 - 88,341,098 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,609,822 - 136,626,851 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,526,690 - 140,538,705 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,526,690 - 140,538,705 (+)Ensemblpanpan1.1panPan2
NDUFS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,271,603 - 21,281,140 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,271,675 - 21,285,279 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,346,459 - 21,356,011 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,389,447 - 21,399,000 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,389,447 - 21,398,979 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,285,733 - 21,286,858 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,691,735 - 21,701,283 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,100,884 - 22,110,441 (-)NCBIUU_Cfam_GSD_1.0
Ndufs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,294,911 - 7,305,582 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903499,300 - 514,893 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903503,633 - 514,235 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,246,960 - 89,257,085 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,246,958 - 89,257,090 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,103,640 - 97,113,761 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,767,864 - 2,780,336 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,768,064 - 2,780,704 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,816,231 - 1,830,038 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794172,707 - 185,073 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794172,543 - 189,031 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000019442   ⟹   ENSCLAP00000019255
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546812,961,915 - 12,971,095 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000019443   ⟹   ENSCLAP00000019256
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546812,961,915 - 12,971,095 (+)Ensembl
RefSeq Acc Id: XM_005400268   ⟹   XP_005400325
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546812,961,873 - 12,971,278 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005400325 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019255
  ENSCLAP00000019255.1
  ENSCLAP00000019256.1
RefSeq Acc Id: XP_005400325   ⟸   XM_005400268
- UniProtKB: A0A8C2VR21 (UniProtKB/TrEMBL),   A0A8C2VYB1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000019255   ⟸   ENSCLAT00000019442
Ensembl Acc Id: ENSCLAP00000019256   ⟸   ENSCLAT00000019443

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013194 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019442 ENTREZGENE
  ENSCLAT00000019442.1 UniProtKB/TrEMBL
  ENSCLAT00000019443.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.645.10 UniProtKB/TrEMBL
InterPro NADH_Q_OxRdtase_suD UniProtKB/TrEMBL
  NADH_UbQ_OxRdtase_49kDa_CS UniProtKB/TrEMBL
  NDH1_su_D/H UniProtKB/TrEMBL
  NiFe-Hase_large UniProtKB/TrEMBL
NCBI Gene Ndufs2 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR11993 UniProtKB/TrEMBL
Pfam Complex1_49kDa UniProtKB/TrEMBL
PROSITE COMPLEX1_49K UniProtKB/TrEMBL
Superfamily-SCOP SSF56762 UniProtKB/TrEMBL
UniProt A0A8C2VR21 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VYB1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Ndufs2  NADH:ubiquinone oxidoreductase core subunit S2    NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)  Symbol and/or name change 5135510 APPROVED