Phc1 (polyhomeotic homolog 1) - Rat Genome Database

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Gene: Phc1 (polyhomeotic homolog 1) Heterocephalus glaber
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Symbol: Phc1
Name: polyhomeotic homolog 1
RGD ID: 18907313
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); histone binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cellular response to retinoic acid (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH dilated cardiomyopathy (ortholog); Germ Cell and Embryonal Neoplasms (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); PcG protein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polyhomeotic-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248604,720,722 - 4,747,456 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Phc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248604,720,722 - 4,747,456 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PHC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,913,843 - 8,941,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,913,896 - 8,941,467 (+)EnsemblGRCh38hg38GRCh38
GRCh37129,066,439 - 9,094,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,958,583 - 8,985,330 (+)NCBINCBI36Build 36hg18NCBI36
Build 34128,958,532 - 8,984,156NCBI
Celera1210,604,723 - 10,631,471 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef128,847,980 - 8,874,662 (+)NCBIHuRef
CHM1_1129,036,292 - 9,063,026 (+)NCBICHM1_1
T2T-CHM13v2.0128,896,088 - 8,923,703 (+)NCBIT2T-CHM13v2.0
Phc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396122,294,690 - 122,317,551 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6122,294,690 - 122,317,520 (-)EnsemblGRCm39 Ensembl
GRCm386122,317,731 - 122,340,227 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6122,317,731 - 122,340,561 (-)EnsemblGRCm38mm10GRCm38
MGSCv376122,267,749 - 122,287,033 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366122,283,350 - 122,302,616 (-)NCBIMGSCv36mm8
Celera6124,111,949 - 124,131,254 (-)NCBICelera
Cytogenetic Map6F1NCBI
cM Map657.52NCBI
Phc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,182,348 - 157,205,504 (-)NCBIGRCr8
mRatBN7.24155,510,274 - 155,532,636 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4155,510,274 - 155,533,959 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4161,773,522 - 161,795,581 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04157,556,705 - 157,578,801 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04156,201,613 - 156,223,733 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04155,093,947 - 155,118,838 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,093,949 - 155,116,154 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,121,134 - 222,143,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44158,736,736 - 158,759,429 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14158,982,409 - 159,004,315 (-)NCBI
Celera4144,331,497 - 144,353,650 (-)NCBICelera
Cytogenetic Map4q42NCBI
Phc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554136,156,934 - 6,176,460 (-)NCBIChiLan1.0ChiLan1.0
PHC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21014,440,722 - 14,467,037 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11214,437,482 - 14,463,797 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,999,018 - 9,025,900 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1129,230,801 - 9,257,811 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl129,231,394 - 9,257,806 (+)Ensemblpanpan1.1panPan2
PHC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,797,327 - 36,816,726 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2736,797,927 - 36,819,386 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha279,800,373 - 9,819,772 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02737,145,820 - 37,165,431 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,145,621 - 37,167,108 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,026,319 - 37,049,023 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,061,391 - 37,081,063 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0279,331,615 - 9,351,225 (+)NCBIUU_Cfam_GSD_1.0
Phc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494598,470,772 - 98,495,688 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936870277,252 - 303,125 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936870275,764 - 300,460 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl562,557,776 - 62,580,651 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1562,557,774 - 62,580,640 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2565,355,682 - 65,378,586 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PHC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,733,769 - 8,759,430 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,733,988 - 8,758,600 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666089829,972 - 856,201 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004869509   ⟹   XP_004869566
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248604,720,722 - 4,747,456 (-)NCBI
RefSeq Acc Id: XM_021248045   ⟹   XP_021103704
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248604,720,722 - 4,739,654 (-)NCBI
RefSeq Acc Id: XM_021248046   ⟹   XP_021103705
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248604,720,722 - 4,739,654 (-)NCBI
RefSeq Acc Id: XM_021248047   ⟹   XP_021103706
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248604,720,722 - 4,739,654 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004869566 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103704 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103705 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103706 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001341
  ENSHGLP00000001342
RefSeq Acc Id: XP_004869566   ⟸   XM_004869509
- Peptide Label: isoform X4
- UniProtKB: G5BPM4 (UniProtKB/TrEMBL),   A0AAX6Q7R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103706   ⟸   XM_021248047
- Peptide Label: isoform X3
- UniProtKB: G5BPM4 (UniProtKB/TrEMBL),   A0AAX6S2I9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103705   ⟸   XM_021248046
- Peptide Label: isoform X2
- UniProtKB: G5BPM4 (UniProtKB/TrEMBL),   A0AAX6S7T9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103704   ⟸   XM_021248045
- Peptide Label: isoform X1
- UniProtKB: G5BPM4 (UniProtKB/TrEMBL),   A0AAX6S4Y9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001045 ENTREZGENE
Ensembl Transcript ENSHGLT00000001383 ENTREZGENE
  ENSHGLT00000001384 ENTREZGENE
Gene3D-CATH 3.30.60.160 UniProtKB/TrEMBL
  Transcription Factor, Ets-1 UniProtKB/TrEMBL
InterPro PcG_chromatin_remod_factors UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Znf_FCS UniProtKB/TrEMBL
  Znf_FCS_sf UniProtKB/TrEMBL
NCBI Gene Phc1 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/TrEMBL
  POLYHOMEOTIC-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam PHC2_SAM_assoc UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
  zf-FCS_1 UniProtKB/TrEMBL
PROSITE SAM_DOMAIN UniProtKB/TrEMBL
  ZF_FCS UniProtKB/TrEMBL
SMART SAM UniProtKB/TrEMBL
Superfamily-SCOP SAM/Pointed domain UniProtKB/TrEMBL
UniProt A0AAX6Q7R4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S2I9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S4Y9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S7T9 ENTREZGENE, UniProtKB/TrEMBL
  G5BPM4 ENTREZGENE, UniProtKB/TrEMBL