PHC1 (polyhomeotic homolog 1) - Rat Genome Database

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Gene: PHC1 (polyhomeotic homolog 1) Pan paniscus
Analyze
Symbol: PHC1
Name: polyhomeotic homolog 1
RGD ID: 11985873
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); histone binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cellular response to retinoic acid (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH genetic disease (ortholog); Germ Cell and Embryonal Neoplasms (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN nuclear body (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polyhomeotic-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21014,440,722 - 14,467,037 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11214,437,482 - 14,463,797 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,999,018 - 9,025,900 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1129,230,801 - 9,257,811 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl129,231,394 - 9,257,806 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PHC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21014,440,722 - 14,467,037 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11214,437,482 - 14,463,797 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,999,018 - 9,025,900 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1129,230,801 - 9,257,811 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl129,231,394 - 9,257,806 (+)Ensemblpanpan1.1panPan2
PHC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,913,843 - 8,941,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,913,896 - 8,941,467 (+)EnsemblGRCh38hg38GRCh38
GRCh37129,067,105 - 9,094,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,958,583 - 8,985,330 (+)NCBINCBI36Build 36hg18NCBI36
Build 34128,958,532 - 8,984,156NCBI
Celera1210,604,723 - 10,631,471 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef128,847,980 - 8,874,662 (+)NCBIHuRef
CHM1_1129,036,292 - 9,063,026 (+)NCBICHM1_1
T2T-CHM13v2.0128,896,088 - 8,923,703 (+)NCBIT2T-CHM13v2.0
Phc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396122,294,690 - 122,317,551 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6122,294,690 - 122,317,520 (-)EnsemblGRCm39 Ensembl
GRCm386122,317,731 - 122,340,227 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6122,317,731 - 122,340,561 (-)EnsemblGRCm38mm10GRCm38
MGSCv376122,267,749 - 122,287,033 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366122,283,350 - 122,302,616 (-)NCBIMGSCv36mm8
Celera6124,111,949 - 124,131,254 (-)NCBICelera
Cytogenetic Map6F1NCBI
cM Map657.52NCBI
Phc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,182,348 - 157,205,504 (-)NCBIGRCr8
mRatBN7.24155,510,274 - 155,532,636 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4155,510,274 - 155,533,959 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4161,773,522 - 161,795,581 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04157,556,705 - 157,578,801 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04156,201,613 - 156,223,733 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04155,093,947 - 155,118,838 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,093,949 - 155,116,154 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,121,134 - 222,143,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44158,736,736 - 158,759,429 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14158,982,409 - 159,004,315 (-)NCBI
Celera4144,331,497 - 144,353,650 (-)NCBICelera
Cytogenetic Map4q42NCBI
Phc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554136,156,934 - 6,176,460 (-)NCBIChiLan1.0ChiLan1.0
PHC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,797,327 - 36,816,726 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2736,797,927 - 36,819,386 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha279,800,373 - 9,819,772 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02737,145,820 - 37,165,431 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,145,621 - 37,167,108 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,026,319 - 37,049,023 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,061,391 - 37,081,063 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0279,331,615 - 9,351,225 (+)NCBIUU_Cfam_GSD_1.0
Phc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494598,470,772 - 98,495,688 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936870277,252 - 303,125 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936870275,764 - 300,460 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl562,557,776 - 62,580,651 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1562,557,774 - 62,580,640 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2565,355,682 - 65,378,586 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PHC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,733,769 - 8,759,430 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,733,988 - 8,758,600 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666089829,972 - 856,201 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248604,720,722 - 4,747,456 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000036573   ⟹   ENSPPAP00000013898
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl129,231,394 - 9,257,806 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036585   ⟹   ENSPPAP00000013910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl129,234,362 - 9,255,804 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036590   ⟹   ENSPPAP00000013915
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl129,234,362 - 9,255,804 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036596   ⟹   ENSPPAP00000013921
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl129,234,362 - 9,241,661 (+)Ensembl
RefSeq Acc Id: XM_008960723   ⟹   XP_008958971
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,442,577 - 14,467,037 (+)NCBI
NHGRI_mPanPan11214,438,244 - 14,463,797 (+)NCBI
Mhudiblu_PPA_v0129,002,714 - 9,025,330 (+)NCBI
PanPan1.1129,234,318 - 9,256,642 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960730   ⟹   XP_008958978
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,441,284 - 14,467,037 (+)NCBI
NHGRI_mPanPan11214,438,236 - 14,463,797 (+)NCBI
Mhudiblu_PPA_v0128,999,770 - 9,025,330 (+)NCBI
PanPan1.1129,231,400 - 9,256,642 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960732   ⟹   XP_008958980
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,440,722 - 14,467,037 (+)NCBI
NHGRI_mPanPan11214,437,482 - 14,463,797 (+)NCBI
Mhudiblu_PPA_v0128,999,018 - 9,025,330 (+)NCBI
PanPan1.1129,230,830 - 9,256,642 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055095365   ⟹   XP_054951340
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,442,577 - 14,467,037 (+)NCBI
NHGRI_mPanPan11214,438,244 - 14,463,797 (+)NCBI
RefSeq Acc Id: XM_055095366   ⟹   XP_054951341
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,442,577 - 14,467,037 (+)NCBI
NHGRI_mPanPan11214,438,244 - 14,463,797 (+)NCBI
RefSeq Acc Id: XM_055095367   ⟹   XP_054951342
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,442,577 - 14,467,037 (+)NCBI
NHGRI_mPanPan11214,438,244 - 14,463,797 (+)NCBI
RefSeq Acc Id: XM_055095368   ⟹   XP_054951343
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,442,577 - 14,467,037 (+)NCBI
NHGRI_mPanPan11214,438,244 - 14,463,797 (+)NCBI
RefSeq Acc Id: XM_063592976   ⟹   XP_063449046
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21014,442,577 - 14,467,037 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008958980   ⟸   XM_008960732
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AEF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008958978   ⟸   XM_008960730
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AEF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008958971   ⟸   XM_008960723
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AEF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000013898   ⟸   ENSPPAT00000036573
RefSeq Acc Id: ENSPPAP00000013921   ⟸   ENSPPAT00000036596
RefSeq Acc Id: ENSPPAP00000013915   ⟸   ENSPPAT00000036590
RefSeq Acc Id: ENSPPAP00000013910   ⟸   ENSPPAT00000036585
RefSeq Acc Id: XP_054951342   ⟸   XM_055095367
- Peptide Label: isoform X6
- UniProtKB: A0A2R9AEF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054951340   ⟸   XM_055095365
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AEF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054951341   ⟸   XM_055095366
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AEF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054951343   ⟸   XM_055095368
- Peptide Label: isoform X7
- UniProtKB: A0A2R9AEF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063449046   ⟸   XM_063592976
- Peptide Label: isoform X1
Protein Domains
FCS-type   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030042 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036573.1 UniProtKB/TrEMBL
  ENSPPAT00000036585.1 UniProtKB/TrEMBL
  ENSPPAT00000036590.1 UniProtKB/TrEMBL
  ENSPPAT00000036596.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  3.30.60.160 UniProtKB/TrEMBL
InterPro SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Znf_FCS UniProtKB/TrEMBL
  Znf_FCS_sf UniProtKB/TrEMBL
KEGG Report pps:100977709 UniProtKB/TrEMBL
NCBI Gene PHC1 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/TrEMBL
  POLYHOMEOTIC-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam PHC2_SAM_assoc UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
  zf-FCS_1 UniProtKB/TrEMBL
PROSITE SAM_DOMAIN UniProtKB/TrEMBL
  ZF_FCS UniProtKB/TrEMBL
SMART SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
UniProt A0A2R9A9G6_PANPA UniProtKB/TrEMBL
  A0A2R9A9H0_PANPA UniProtKB/TrEMBL
  A0A2R9AAJ3_PANPA UniProtKB/TrEMBL
  A0A2R9AEF7 ENTREZGENE, UniProtKB/TrEMBL