Trim26 (tripartite motif containing 26) - Rat Genome Database

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Gene: Trim26 (tripartite motif containing 26) Heterocephalus glaber
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Symbol: Trim26
Name: tripartite motif containing 26
RGD ID: 18906217
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of viral entry into host cell (ortholog); positive regulation of DNA-binding transcription factor activity (ortholog); positive regulation of non-canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH megacolon (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Tripartite motif-containing protein 26
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,230,073 - 25,259,980 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,238,992 - 25,258,454 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
megacolon  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Trim26
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,230,073 - 25,259,980 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,238,992 - 25,258,454 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TRIM26
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,184,455 - 30,213,406 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,184,455 - 30,213,427 (-)EnsemblGRCh38hg38GRCh38
GRCh37630,152,232 - 30,181,183 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,260,211 - 30,289,132 (-)NCBINCBI36Build 36hg18NCBI36
Build 34630,260,212 - 30,289,132NCBI
Celera631,750,448 - 31,779,361 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,950,359 - 29,979,394 (-)NCBIHuRef
CHM1_1630,154,280 - 30,183,313 (-)NCBICHM1_1
T2T-CHM13v2.0630,048,685 - 30,077,640 (-)NCBIT2T-CHM13v2.0
Trim26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,148,016 - 37,170,290 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,148,026 - 37,170,290 (+)EnsemblGRCm39 Ensembl
GRCm381736,837,123 - 36,859,398 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,837,134 - 36,859,398 (+)EnsemblGRCm38mm10GRCm38
MGSCv371736,974,086 - 36,996,325 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361736,445,234 - 36,467,430 (+)NCBIMGSCv36mm8
Celera1740,256,349 - 40,278,617 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
Trim26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,711,564 - 1,736,389 (-)NCBIGRCr8
mRatBN7.2201,708,297 - 1,731,176 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,709,788 - 1,731,120 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,763,180 - 1,784,479 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,766,682 - 1,787,982 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,707,225 - 1,728,659 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0202,201,685 - 2,224,481 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl202,201,683 - 2,224,463 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0204,239,932 - 4,248,755 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,802,458 - 1,811,283 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,802,469 - 1,811,281 (-)NCBI
Celera202,418,533 - 2,427,356 (-)NCBICelera
Cytogenetic Map20p12NCBI
Trim26
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583303,081 - 325,560 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955583303,081 - 325,560 (-)NCBIChiLan1.0ChiLan1.0
TRIM26
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,778,465 - 44,808,518 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1640,741,475 - 40,769,319 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,962,838 - 29,990,710 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1630,632,948 - 30,660,809 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,632,948 - 30,660,809 (-)Ensemblpanpan1.1panPan2
LOC119867740
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.03526,693,865 - 26,715,915 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13526,348,104 - 26,370,104 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03526,409,307 - 26,431,249 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,879,397 - 27,901,449 (-)NCBIUU_Cfam_GSD_1.0
Trim26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,732,023 - 32,762,964 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936723829,568 - 859,817 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936723827,847 - 859,860 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM26
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,757,794 - 22,780,232 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,757,794 - 22,767,662 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,795,848 - 24,819,779 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM26
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,284,454 - 42,312,150 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1742,283,713 - 42,313,292 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604429,844,053 - 29,873,853 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027567   ⟹   ENSHGLP00000027325
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475425,230,073 - 25,259,980 (+)Ensembl
RefSeq Acc Id: XM_004847112   ⟹   XP_004847169
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475425,239,025 - 25,258,454 (+)NCBI
RefSeq Acc Id: XM_004847113   ⟹   XP_004847170
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475425,249,240 - 25,258,454 (+)NCBI
RefSeq Acc Id: XM_021260178   ⟹   XP_021115837
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475425,249,674 - 25,258,454 (+)NCBI
RefSeq Acc Id: XM_021260179   ⟹   XP_021115838
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475425,238,992 - 25,258,454 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004847169 (Get FASTA)   NCBI Sequence Viewer  
  XP_004847170 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115837 (Get FASTA)   NCBI Sequence Viewer  
  XP_021115838 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16021 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027325
  ENSHGLP00000050479
RefSeq Acc Id: XP_021115838   ⟸   XM_021260179
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004847169   ⟸   XM_004847112
- Peptide Label: isoform X3
- UniProtKB: G5C3B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004847170   ⟸   XM_004847113
- Peptide Label: isoform X3
- UniProtKB: G5C3B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021115837   ⟸   XM_021260178
- Peptide Label: isoform X1
Ensembl Acc Id: ENSHGLP00000027325   ⟸   ENSHGLT00000027567


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019427 Ensembl, ENTREZGENE
  ENSHGLG00000036187 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027567 ENTREZGENE
  ENSHGLT00000044862 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  TRIM/RBCC UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report hgl:101714616 UniProtKB/TrEMBL
NCBI Gene Trim26 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/TrEMBL
  TRIPARTITE MOTIF-CONTAINING PROTEIN 26 UniProtKB/TrEMBL
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-C3HC4_4 UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt G5C3B0 ENTREZGENE, UniProtKB/TrEMBL