Gast (gastrin) - Rat Genome Database

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Gene: Gast (gastrin) Heterocephalus glaber
Analyze
Symbol: Gast
Name: gastrin
RGD ID: 18905495
Description: ENCODES a protein that exhibits hormone activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Barrett's esophagus (ortholog); Colonic Neoplasms (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,976,380 - 1,976,819 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,976,170 - 1,976,819 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GastNaked Mole-Ratadenocarcinoma  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:3952654
GastNaked Mole-RatBarrett's esophagus  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15387324
GastNaked Mole-RatColonic Neoplasms  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:3952654
GastNaked Mole-Ratgastrointestinal system disease  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:12729842
GastNaked Mole-RatLung Neoplasms  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:11208460
GastNaked Mole-Ratpeptic ulcer disease  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:10700044
GastNaked Mole-RatReperfusion Injury  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:10594344
GastNaked Mole-RatStomach Neoplasms  ISOGAST (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15492468


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GastNaked Mole-RatG protein-coupled receptor signaling pathway  ISOGast (Rattus norvegicus)9068941 RGDPMID:11788349 and REF_RGD_ID:619539
GastNaked Mole-RatG protein-coupled receptor signaling pathway involved_inIEAPANTHER:PTN000448324150520179 TreeGrafterGO_REF:0000118
GastNaked Mole-Ratresponse to food involved_inIEAPANTHER:PTN000448324150520179 TreeGrafterGO_REF:0000118

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GastNaked Mole-Ratextracellular region located_inIEAInterPro:IPR001651150520179 InterProGO_REF:0000002
GastNaked Mole-Ratextracellular region located_inIEAUniProtKB-SubCell:SL-0243150520179 UniProtGO_REF:0000044
GastNaked Mole-Ratextracellular region located_inIEAUniProtKB-KW:KW-0964150520179 UniProtGO_REF:0000043
GastNaked Mole-Ratextracellular space located_inIEAPANTHER:PTN000448324150520179 TreeGrafterGO_REF:0000118

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GastNaked Mole-Rathormone activity  ISOGast (Rattus norvegicus)9068941 RGDPMID:12388195 and REF_RGD_ID:632782
GastNaked Mole-Rathormone activity enablesIEAInterPro:IPR001651 and InterPro:IPR039236150520179 InterProGO_REF:0000002
GastNaked Mole-Rathormone activity enablesIEAUniProtKB-KW:KW-0372150520179 UniProtGO_REF:0000043
GastNaked Mole-Rathormone activity enablesIEAPANTHER:PTN000448324150520179 TreeGrafterGO_REF:0000118
GastNaked Mole-Ratprotein binding enablesISOUniProtKB:P027879068941 PMID:19664057IntActPMID:19664057
GastNaked Mole-Ratprotein binding enablesISOPR:P564819068941 PMID:8876222MGIPMID:8876222
GastNaked Mole-Ratprotein binding enablesISOUniProtKB:O43315 more ...9068941 PMID:32296183IntActPMID:32296183
GastNaked Mole-Ratprotein binding enablesISOgastrin9068941 PMID:7681836GO_CentralPMID:7681836

Imported Annotations - SMPDB

1 to 11 of 11 rows
1 to 11 of 11 rows
PMID:22301074   PMID:30032202  



Gast
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,976,380 - 1,976,819 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,976,170 - 1,976,819 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GAST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,712,331 - 41,715,969 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,712,331 - 41,715,969 (+)EnsemblGRCh38hg38GRCh38
GRCh371739,868,583 - 39,872,221 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,122,139 - 37,125,747 (+)NCBINCBI36Build 36hg18NCBI36
Build 341737,122,105 - 37,125,749NCBI
Celera1736,519,728 - 36,523,335 (+)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,630,734 - 35,634,345 (+)NCBIHuRef
CHM1_11740,104,051 - 40,107,693 (+)NCBICHM1_1
T2T-CHM13v2.01742,568,780 - 42,572,417 (+)NCBIT2T-CHM13v2.0
Gast
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,225,233 - 100,227,823 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,225,233 - 100,227,822 (+)EnsemblGRCm39 Ensembl
GRCm3811100,334,407 - 100,336,997 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,334,407 - 100,336,996 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711100,195,726 - 100,198,310 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,150,497 - 100,153,086 (+)NCBIMGSCv36mm8
Celera11110,951,803 - 110,954,387 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.46NCBI
Gast
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81085,765,216 - 85,767,881 (+)NCBIGRCr8
mRatBN7.21085,264,832 - 85,269,393 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,264,832 - 85,267,496 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,304,617 - 90,307,386 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01089,782,921 - 89,785,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,173,120 - 85,175,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,245,532 - 88,248,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,245,532 - 88,248,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,038,779 - 88,041,731 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,273,628 - 89,276,192 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,287,997 - 89,290,562 (+)NCBI
Celera1083,982,177 - 83,985,941 (+)NCBICelera
Cytogenetic Map10q31NCBI
Gast
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545115,987,597 - 15,988,131 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545115,987,160 - 15,988,067 (+)NCBIChiLan1.0ChiLan1.0
GAST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21923,265,782 - 23,270,765 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,155,901 - 25,160,884 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,597,741 - 15,602,724 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,816,656 - 15,820,296 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,816,656 - 15,820,296 (-)Ensemblpanpan1.1panPan2
GAST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,081,638 - 21,084,122 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,081,639 - 21,083,932 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,543,614 - 20,545,919 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,802,583 - 21,804,888 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,802,584 - 21,804,877 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,588,491 - 20,590,796 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,854,461 - 20,856,766 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,958,434 - 20,960,739 (-)NCBIUU_Cfam_GSD_1.0
Gast
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560220,438,522 - 20,441,534 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649016,636,146 - 16,636,548 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649016,636,146 - 16,636,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,953,202 - 20,955,434 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,953,202 - 20,955,434 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,119,838 - 21,123,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GAST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,526,548 - 64,532,145 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,526,636 - 64,527,080 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,361,331 - 35,361,996 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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RefSeq Transcripts XM_004859840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01067292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000018700   ⟹   ENSHGLP00000018516
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247951,976,380 - 1,976,819 (-)Ensembl
RefSeq Acc Id: XM_004859840   ⟹   XP_004859897
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247951,976,170 - 1,976,819 (-)NCBI
Protein RefSeqs XP_004859897 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018516
RefSeq Acc Id: XP_004859897   ⟸   XM_004859840
- UniProtKB: G5B0M1 (UniProtKB/TrEMBL),   A0AAX6PTZ8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018516   ⟸   ENSHGLT00000018700



1 to 13 of 13 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000013252 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000018700 ENTREZGENE
InterPro GAST UniProtKB/TrEMBL
  Gastrin/CCK UniProtKB/TrEMBL
  Gastrin/cholecystokinin_CS UniProtKB/TrEMBL
NCBI Gene Gast ENTREZGENE
PANTHER GASTRIN UniProtKB/TrEMBL
  GASTRIN UniProtKB/TrEMBL
Pfam Gastrin UniProtKB/TrEMBL
PROSITE GASTRIN UniProtKB/TrEMBL
SMART GASTRIN UniProtKB/TrEMBL
UniProt A0AAX6PTZ8 ENTREZGENE, UniProtKB/TrEMBL
  G5B0M1 ENTREZGENE, UniProtKB/TrEMBL
1 to 13 of 13 rows