Gast (gastrin) - Rat Genome Database

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Gene: Gast (gastrin) Heterocephalus glaber
Analyze
Symbol: Gast
Name: gastrin
RGD ID: 18905495
Description: ENCODES a protein that exhibits hormone activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Barrett's esophagus (ortholog); Colonic Neoplasms (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,976,380 - 1,976,819 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,976,170 - 1,976,819 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gast
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,976,380 - 1,976,819 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,976,170 - 1,976,819 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GAST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,712,331 - 41,715,969 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,712,331 - 41,715,969 (+)EnsemblGRCh38hg38GRCh38
GRCh371739,868,583 - 39,872,221 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,122,139 - 37,125,747 (+)NCBINCBI36Build 36hg18NCBI36
Build 341737,122,105 - 37,125,749NCBI
Celera1736,519,728 - 36,523,335 (+)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,630,734 - 35,634,345 (+)NCBIHuRef
CHM1_11740,104,051 - 40,107,693 (+)NCBICHM1_1
T2T-CHM13v2.01742,568,780 - 42,572,417 (+)NCBIT2T-CHM13v2.0
Gast
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,225,233 - 100,227,823 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,225,233 - 100,227,822 (+)EnsemblGRCm39 Ensembl
GRCm3811100,334,407 - 100,336,997 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,334,407 - 100,336,996 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711100,195,726 - 100,198,310 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,150,497 - 100,153,086 (+)NCBIMGSCv36mm8
Celera11110,951,803 - 110,954,387 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.46NCBI
Gast
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81085,765,216 - 85,767,881 (+)NCBIGRCr8
mRatBN7.21085,264,832 - 85,269,393 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,264,832 - 85,267,496 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,304,617 - 90,307,386 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01089,782,921 - 89,785,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,173,120 - 85,175,782 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,245,532 - 88,248,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,245,532 - 88,248,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,038,779 - 88,041,731 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,273,628 - 89,276,192 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,287,997 - 89,290,562 (+)NCBI
Celera1083,982,177 - 83,985,941 (+)NCBICelera
Cytogenetic Map10q31NCBI
Gast
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545115,987,597 - 15,988,131 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545115,987,160 - 15,988,067 (+)NCBIChiLan1.0ChiLan1.0
GAST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21923,265,782 - 23,270,765 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,155,901 - 25,160,884 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,597,741 - 15,602,724 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,816,656 - 15,820,296 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,816,656 - 15,820,296 (-)Ensemblpanpan1.1panPan2
GAST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,081,638 - 21,084,122 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,081,639 - 21,083,932 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,543,614 - 20,545,919 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,802,583 - 21,804,888 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,802,584 - 21,804,877 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,588,491 - 20,590,796 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,854,461 - 20,856,766 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,958,434 - 20,960,739 (-)NCBIUU_Cfam_GSD_1.0
Gast
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560220,438,522 - 20,441,534 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649016,636,146 - 16,636,548 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649016,636,146 - 16,636,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,953,202 - 20,955,434 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,953,202 - 20,955,434 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,119,838 - 21,123,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GAST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,526,548 - 64,532,145 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,526,636 - 64,527,080 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,361,331 - 35,361,996 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004859840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01067292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000018700   ⟹   ENSHGLP00000018516
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247951,976,380 - 1,976,819 (-)Ensembl
RefSeq Acc Id: XM_004859840   ⟹   XP_004859897
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247951,976,170 - 1,976,819 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004859897 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018516
RefSeq Acc Id: XP_004859897   ⟸   XM_004859840
- UniProtKB: G5B0M1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018516   ⟸   ENSHGLT00000018700


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013252 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000018700 ENTREZGENE
InterPro GAST UniProtKB/TrEMBL
  Gastrin/CCK UniProtKB/TrEMBL
  Gastrin/cholecystokinin_CS UniProtKB/TrEMBL
NCBI Gene Gast ENTREZGENE
PANTHER GASTRIN UniProtKB/TrEMBL
  GASTRIN UniProtKB/TrEMBL
Pfam Gastrin UniProtKB/TrEMBL
PROSITE GASTRIN UniProtKB/TrEMBL
UniProt G5B0M1 ENTREZGENE, UniProtKB/TrEMBL