GAST (gastrin) - Rat Genome Database

Name: GAST
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: GAST (gastrin) Chlorocebus sabaeus

Analyze

Symbol:

GAST

Name:

gastrin

RGD ID:

18349766

Description:

ENCODES a protein that exhibits hormone activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Barrett's esophagus (ortholog); Colonic Neoplasms (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GAST (gastrin)	NCBI	Ortholog
Mus musculus (house mouse):	Gast (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Gast (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gast (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GAST (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GAST (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gast (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GAST (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gast (gastrin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	64,526,548 - 64,532,145 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	64,526,636 - 64,527,080 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	35,361,331 - 35,361,996 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenocarcinoma (ISO)

Barrett's esophagus (ISO)

Colonic Neoplasms (ISO)

gastrointestinal system disease (ISO)

genetic disease (ISO)

Lung Neoplasms (ISO)

peptic ulcer disease (ISO)

Reperfusion Injury (ISO)

Stomach Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA,ISO)

response to food (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

Molecular Function

hormone activity (IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

cimetidine pharmacodynamics pathway (ISO)

esomeprazole pharmacodynamics pathway (ISO)

famotidine pharmacodynamics pathway (ISO)

lansoprazole pharmacodynamics pathway (ISO)

nizatidine pharmacodynamics pathway (ISO)

omeprazole pharmacodynamics pathway (ISO)

pantoprazole pharmacodynamics pathway (ISO)

pirenzepine pharmacodynamics pathway (ISO)

rabeprazole pharmacodynamics pathway (ISO)

ranitidine pharmacodynamics pathway (ISO)

roxatidine acetate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GAST
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	64,526,548 - 64,532,145 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	64,526,636 - 64,527,080 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	35,361,331 - 35,361,996 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

GAST
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	41,712,331 - 41,715,969 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	41,712,331 - 41,715,969 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	39,868,583 - 39,872,221 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	37,122,139 - 37,125,747 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	37,122,105 - 37,125,749	NCBI
Celera	17	36,519,728 - 36,523,335 (+)	NCBI		Celera
Cytogenetic Map	17	q21.2	NCBI
HuRef	17	35,630,734 - 35,634,345 (+)	NCBI		HuRef
CHM1_1	17	40,104,051 - 40,107,693 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	42,568,780 - 42,572,417 (+)	NCBI		T2T-CHM13v2.0

Gast
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	100,225,233 - 100,227,823 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	100,225,233 - 100,227,822 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	100,334,407 - 100,336,997 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	100,334,407 - 100,336,996 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	100,195,726 - 100,198,310 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	100,150,497 - 100,153,086 (+)	NCBI		MGSCv36	mm8
Celera	11	110,951,803 - 110,954,387 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	63.46	NCBI

Gast
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	85,765,216 - 85,767,881 (+)	NCBI		GRCr8
mRatBN7.2	10	85,264,832 - 85,269,393 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	85,264,832 - 85,267,496 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	90,304,617 - 90,307,386 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	89,782,921 - 89,785,593 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	85,173,120 - 85,175,782 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	88,245,532 - 88,248,485 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	88,245,532 - 88,248,484 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	88,038,779 - 88,041,731 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	89,273,628 - 89,276,192 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	89,287,997 - 89,290,562 (+)	NCBI
Celera	10	83,982,177 - 83,985,941 (+)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

Gast
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	15,987,597 - 15,988,131 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	15,987,160 - 15,988,067 (+)	NCBI	ChiLan1.0	ChiLan1.0

GAST
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	23,265,782 - 23,270,765 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	25,155,901 - 25,160,884 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	15,597,741 - 15,602,724 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	15,816,656 - 15,820,296 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	15,816,656 - 15,820,296 (-)	Ensembl	panpan1.1		panPan2

GAST
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	21,081,638 - 21,084,122 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	21,081,639 - 21,083,932 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	20,543,614 - 20,545,919 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	21,802,583 - 21,804,888 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	21,802,584 - 21,804,877 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	20,588,491 - 20,590,796 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	20,854,461 - 20,856,766 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	20,958,434 - 20,960,739 (-)	NCBI		UU_Cfam_GSD_1.0

Gast
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	20,438,522 - 20,441,534 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	16,636,146 - 16,636,548 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	16,636,146 - 16,636,548 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GAST
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	20,953,202 - 20,955,434 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	20,953,202 - 20,955,434 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	21,119,838 - 21,123,391 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Gast
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	1,976,380 - 1,976,819 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	1,976,170 - 1,976,819 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008012702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000001040 ⟹ ENSCSAP00000015030

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	64,526,636 - 64,527,080 (-)	Ensembl

RefSeq Acc Id:

XM_008012702 ⟹ XP_008010893

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	64,526,548 - 64,532,145 (-)	NCBI
Vero_WHO_p1.0	NW_023666077	35,361,331 - 35,361,996 (-)	NCBI

Sequence:

show sequence

CTTGACCTCGTGATCTGCTCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCA
CGCCCAGCCAAATAGTGACATTCTAACCATCGCCTGTGGAATAGAAGACATGCTTCTATTTGTT
GAAATTGCCATCCCTCATGTAACCAGCCTAGGGAAGAACACTCAAGGGGGCATAACCCCCTCCA
CGGGCACAAACTGAGTCTTGGGCTCTGGTACAATCAGGGTTCTACTGAAAGCTTATCATTTCCC
ATTAGAGTTACCACAGCAACACGAATGTCTTCATTCATTCCCCTAGTGCATGAACAGAGCTACA
CCCACCCCACCTGTTCTCCCAAGCCCCCTCAAAGTCCTTCCATCTCTGAGATTCTGTGATTCAA
TTAATCATCACCAATGCCTGCACTGCTTTTTGTCATTTTCATTTATTCCATCTGCTGAGTCACC
ATGTCCTGTTCTGGATCAGAGTGGTTATTCACAATGGTTATTCAGCCGTCAGTTGCCATGGACA
CCGCACAGCCTGCTTCCTTCATCACCCATTAATTCTCACCAAGGCTGGCTGTGAGCATGGGTAC
CACAGCCATTACCCAAGACCCAAGGGGAATCAAACTCTCCCAGAAAAGGAGGGGGCCTGATGAT
GCATGAACAGAAGCAAAATCTCTGCTCTCAATGGTGGAAAAATCAAAAACAGCCTACAACTCAT
TACATCCGGTCAAACCATGTGGAGGCAGCAGTTTATCGAATAAGTCAACAAGACGAGATGCAGC
AACTGTGTGTGTATGTGCTGATCTTTGCACTGGCTCTGGCTGCCTTCTCTGAAGCTTCTTGGAA
GCCCCGCTCCCAGGAGCCAGATGCACCCTTAGGTACAGGGGCCAACAGGAACCTGGAGCTACCC
TGGCTGGACCAGCAAGGCCCAGTCTTTCACCACCGAAGGCACCTGGGACCCCAGGGTCCCCCAC
ACCTCGTGGCAGACCCATCCAAGAAGCAGGGACCATGGATGGAGGAAGAAGAAGAAGCCTATGG
ATGGATGGACTTTGGCCGCCGCAGTGCCGAGGATGAGAACCAACAACCCTAGAACCAAGCTTCA
GAGCCCAGCCACCTCCCACTCCACCCCAGCCCTATCCCCTGAAAAACTAATCAAAAATAAACTA
GTTTCCAGTGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008010893	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000015030.1

RefSeq Acc Id:	XP_008010893 ⟸ XM_008012702
- UniProtKB:	A0A0D9S2E1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000015030 ⟸ ENSCSAT00000001040

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000003011	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000001040.1	UniProtKB/TrEMBL
InterPro	GAST	UniProtKB/TrEMBL
	Gastrin/CCK	UniProtKB/TrEMBL
	Gastrin/cholecystokinin_CS	UniProtKB/TrEMBL
NCBI Gene	GAST	ENTREZGENE
PANTHER	GASTRIN	UniProtKB/TrEMBL
	PTHR19309	UniProtKB/TrEMBL
Pfam	Gastrin	UniProtKB/TrEMBL
PROSITE	GASTRIN	UniProtKB/TrEMBL
SMART	GASTRIN	UniProtKB/TrEMBL
UniProt	A0A0D9S2E1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB