Cdc42bpb (CDC42 binding protein kinase beta) - Rat Genome Database

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Gene: Cdc42bpb (CDC42 binding protein kinase beta) Heterocephalus glaber
Analyze
Symbol: Cdc42bpb
Name: CDC42 binding protein kinase beta
RGD ID: 18902658
Description: ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); small GTPase binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Charcot-Marie-Tooth disease axonal type 2O (ortholog); CHILTON-OKUR-CHUNG NEURODEVELOPMENTAL SYNDROME (ortholog); FOUND IN actomyosin (inferred); cell projection (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase MRCK beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247341,623,956 - 1,722,309 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247341,624,001 - 1,718,427 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cdc42bpb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247341,623,956 - 1,722,309 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247341,624,001 - 1,718,427 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CDC42BPB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814102,932,380 - 103,057,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14102,932,380 - 103,057,549 (-)EnsemblGRCh38hg38GRCh38
GRCh3714103,398,717 - 103,523,886 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614102,468,469 - 102,593,495 (-)NCBINCBI36Build 36hg18NCBI36
Build 3414102,468,469 - 102,593,552NCBI
Celera1483,452,838 - 83,577,854 (-)NCBICelera
Cytogenetic Map14q32.32NCBI
HuRef1483,573,751 - 83,698,598 (-)NCBIHuRef
CHM1_114103,336,156 - 103,461,595 (-)NCBICHM1_1
T2T-CHM13v2.01497,168,625 - 97,293,800 (-)NCBIT2T-CHM13v2.0
Cdc42bpb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,259,406 - 111,347,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,259,410 - 111,344,152 (-)EnsemblGRCm39 Ensembl
GRCm3812111,292,972 - 111,379,313 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,292,976 - 111,377,718 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712112,531,183 - 112,615,929 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,740,787 - 111,825,167 (-)NCBIMGSCv36mm8
Celera12112,487,034 - 112,573,080 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.94NCBI
Cdc42bpb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,154,905 - 136,241,259 (-)NCBIGRCr8
mRatBN7.26130,333,712 - 130,416,631 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,333,712 - 130,416,377 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6130,504,511 - 130,586,328 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06130,800,504 - 130,882,318 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06130,163,771 - 130,246,465 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06135,746,743 - 135,830,144 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,746,754 - 135,830,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,585,365 - 144,667,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,053,885 - 136,136,234 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16136,061,068 - 136,142,380 (-)NCBI
Celera6127,890,990 - 127,973,161 (-)NCBICelera
Cytogenetic Map6q32NCBI
Cdc42bpb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555382,024,776 - 2,113,211 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555382,023,681 - 2,113,213 (-)NCBIChiLan1.0ChiLan1.0
CDC42BPB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215104,084,676 - 104,212,688 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114103,301,174 - 103,429,186 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01483,551,870 - 83,679,888 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114103,367,060 - 103,447,382 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14103,367,060 - 103,451,989 (-)Ensemblpanpan1.1panPan2
CDC42BPB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1870,809,943 - 70,915,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl870,811,023 - 71,033,324 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,322,386 - 70,428,050 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0871,087,229 - 71,192,642 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl871,087,236 - 71,193,245 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1870,750,905 - 70,856,255 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0870,815,280 - 70,920,989 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,215,615 - 71,320,970 (-)NCBIUU_Cfam_GSD_1.0
Cdc42bpb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086403,169,826 - 3,219,970 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936835975,960 - 1,026,025 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936835975,941 - 1,026,046 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC42BPB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27128,824,316 - 128,887,793 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDC42BPB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12480,894,777 - 81,024,998 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605368,085,087 - 68,224,199 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000025580   ⟹   ENSHGLP00000025357
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247341,623,956 - 1,722,309 (+)Ensembl
RefSeq Acc Id: XM_004836907   ⟹   XP_004836964
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247341,624,001 - 1,718,427 (+)NCBI
RefSeq Acc Id: XM_021243949   ⟹   XP_021099608
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247341,654,597 - 1,718,427 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004836964 (Get FASTA)   NCBI Sequence Viewer  
  XP_021099608 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025357
GenBank Protein JAN98295 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004836964   ⟸   XM_004836907
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JUK3 (UniProtKB/TrEMBL),   G5AWG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099608   ⟸   XM_021243949
- Peptide Label: isoform X1
- UniProtKB: G5AWG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000025357   ⟸   ENSHGLT00000025580


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018068 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025580 ENTREZGENE
Gene3D-CATH 1.20.5.340 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  C1-like_sf UniProtKB/TrEMBL
  CNH_dom UniProtKB/TrEMBL
  CRIB_dom UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/TrEMBL
  KELK UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MRCKB_STKc UniProtKB/TrEMBL
  Myotonic_dystrophy_kinase_coil UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report hgl:101717464 UniProtKB/TrEMBL
NCBI Gene Cdc42bpb ENTREZGENE
PANTHER MYOTONIC DYSTROPHY S/T KINASE-RELATED UniProtKB/TrEMBL
  PTHR22988:SF34 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  CNH UniProtKB/TrEMBL
  DMPK_coil UniProtKB/TrEMBL
  KELK UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  CNH UniProtKB/TrEMBL
  CRIB UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART CNH UniProtKB/TrEMBL
  PBD UniProtKB/TrEMBL
  S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
  Tricorn protease domain 2 UniProtKB/TrEMBL
UniProt A0A0P6JUK3 ENTREZGENE, UniProtKB/TrEMBL
  G5AWG6 ENTREZGENE, UniProtKB/TrEMBL