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Gene: Cdc42bpb (CDC42 binding protein kinase beta) Ictidomys tridecemlineatus

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Symbol:

Cdc42bpb

Name:

CDC42 binding protein kinase beta

RGD ID:

12573838

Description:

ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); small GTPase binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Charcot-Marie-Tooth disease axonal type 2O (ortholog); CHILTON-OKUR-CHUNG NEURODEVELOPMENTAL SYNDROME (ortholog); FOUND IN actomyosin (inferred); cell projection (inferred); cytoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine/threonine-protein kinase MRCK beta

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	3,169,826 - 3,219,970 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936835	975,960 - 1,026,025 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936835	975,941 - 1,026,046 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

Charcot-Marie-Tooth disease axonal type 2O (ISO)

CHILTON-OKUR-CHUNG NEURODEVELOPMENTAL SYNDROME (ISO)

genetic disease (ISO)

Imerslund-Grasbeck Syndrome (ISO)

Imerslund-Grasbeck Syndrome 1 (ISO)

Imerslund-Grasbeck Syndrome 2 (ISO)

immunodeficiency 132A (ISO)

megaloblastic anemia (ISO)

mitochondrial complex IV deficiency nuclear type 17 (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (ISO)

actomyosin structure organization (IEA)

cell migration (IEA)

cytoskeleton organization (IEA)

protein phosphorylation (ISO)

Cellular Component

actomyosin (IEA)

cell projection (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

lamellipodium (IEA)

membrane (IEA)

Molecular Function

ATP binding (IEA)

kinase activity (IEA)

metal ion binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IEA,ISO)

protein-containing complex binding (IEA)

small GTPase binding (ISO)

transferase activity (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Cdc42bpb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	3,169,826 - 3,219,970 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936835	975,960 - 1,026,025 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936835	975,941 - 1,026,046 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDC42BPB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	102,932,380 - 103,057,549 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	102,932,380 - 103,057,549 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	103,398,717 - 103,523,886 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	102,468,469 - 102,593,495 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	102,468,469 - 102,593,552	NCBI
Celera	14	83,452,838 - 83,577,854 (-)	NCBI		Celera
Cytogenetic Map	14	q32.32	NCBI
HuRef	14	83,573,751 - 83,698,598 (-)	NCBI		HuRef
CHM1_1	14	103,336,156 - 103,461,595 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	97,168,625 - 97,293,800 (-)	NCBI		T2T-CHM13v2.0

Cdc42bpb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	111,259,406 - 111,347,985 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	111,259,410 - 111,344,152 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	111,292,972 - 111,379,313 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	111,292,976 - 111,377,718 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	112,531,183 - 112,615,929 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	111,740,787 - 111,825,167 (-)	NCBI		MGSCv36	mm8
Celera	12	112,487,034 - 112,573,080 (-)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	60.94	NCBI

Cdc42bpb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	136,154,905 - 136,241,259 (-)	NCBI		GRCr8
mRatBN7.2	6	130,333,712 - 130,416,631 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	130,333,712 - 130,416,377 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	130,504,511 - 130,586,328 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	130,800,504 - 130,882,318 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	130,163,771 - 130,246,465 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	135,746,743 - 135,830,144 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	135,746,754 - 135,830,086 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	144,585,365 - 144,667,686 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	136,053,885 - 136,136,234 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	136,061,068 - 136,142,380 (-)	NCBI
Celera	6	127,890,990 - 127,973,161 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Cdc42bpb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955538	2,024,776 - 2,113,211 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955538	2,023,681 - 2,113,213 (-)	NCBI	ChiLan1.0	ChiLan1.0

CDC42BPB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	104,084,676 - 104,212,688 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	103,301,174 - 103,429,186 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	83,551,870 - 83,679,888 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	103,367,060 - 103,447,382 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	103,367,060 - 103,451,989 (-)	Ensembl	panpan1.1		panPan2

CDC42BPB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	70,809,943 - 70,915,922 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	70,811,023 - 71,033,324 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	70,322,386 - 70,428,050 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	71,087,229 - 71,192,642 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	71,087,236 - 71,193,245 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	70,750,905 - 70,856,255 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	70,815,280 - 70,920,989 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	71,215,615 - 71,320,970 (-)	NCBI		UU_Cfam_GSD_1.0

CDC42BPB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	7	128,824,316 - 128,887,793 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDC42BPB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	80,894,777 - 81,024,998 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666053	68,085,087 - 68,224,199 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdc42bpb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	1,623,956 - 1,722,309 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	1,624,001 - 1,718,427 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005341009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000000766 ⟹ ENSSTOP00000000687

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936835	975,960 - 1,026,025 (-)	Ensembl

RefSeq Acc Id:

XM_005341009 ⟹ XP_005341066

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	3,169,826 - 3,219,970 (+)	NCBI
SpeTri2.0	NW_004936835	975,941 - 1,026,046 (-)	NCBI

Sequence:

show sequence

AAACTCAAATTTGTATTATAGGTTGCTGTTGTTAAAATGAAGAACACTGAACGAATTTACGCCA
TGAAAATTCTCAACAAGTGGGAGATGCTTAAAAGAGCAGAGACCGCCTGTTTCCGGGAGGAGCG
TGATGTGCTAGTGAAGGGCGACTGCCAGTGGATCACCGCGCTGCACTACGCCTTCCAGGACGAG
AACTACCTGTACCTGGTCATGGATTACTACGTGGGTGGTGATTTGCTGACACTACTTAGTAAAT
TTGAAGACAAGCTTCCAGAAGACATGGCAAGGTTCTATATTGGTGAGATGGTGCTGGCCATTGA
CTCCATCCACCAGCTTCATTATGTGCACAGAGACATTAAACCTGACAATGTCCTTTTGGATGTG
AATGGTCATATCCGCCTGGCTGACTTTGGATCCTGTTTGAAGATGAACGATGATGGAACTGTTC
AGTCCTCTGTGGCGGTGGGCACACCTGACTACATTTCACCCGAGATCCTGCAGGCCATGGAGGA
TGGCATGGGCAAATATGGGCCTGAATGTGACTGGTGGTCCCTGGGCGTCTGCATGTACGAGATG
CTTTATGGAGAAACACCGTTTTATGCAGAGTCACTTGTAGAGACGTATGGGAAAATCATGAACC
ATGAGGAGCGATTTCAATTCCCTTCCCATGTCACGGATGTCTCTGAAGAAGCGAAAGACCTCAT
TCAGAGATTGATCTGCAGCAGAGAGCGTCGGCTAGGGCAGAATGGAATAGAGGACTTTAAGAAA
CATGCGTTTTTTGAAGGTCTAAACTGGGAAAATATACGAAACCTAGAAGCACCTTACATTCCTG
ATGTGAGCAGCCCTTCTGACACATCCAACTTCGACGTGGATGACGATGTGCTGAGAAACGCTGA
AATATTACCTCCCGGCTCTCACACCGGCTTCTCTGGATTGCATTTGCCCTTCATTGGCTTCACA
TTCACAACAGAAAGCTGCTTTTCCGACCGTGGCTCTCTGAAGAGCGTGATGCAATCTAACACAT
TAACCAAAGATGAGGATGTGCAGCGGGACTTGGAGAACAGCTTGCAAGTTGAAGCTTATGAGAG
GAGGATACGAAGACTGGAACAGGAAAAGCTGGAGCTGAGCCGGAAGCTGCAGGAGTCCACACAG
ACCGTGCAGTCCCTTCATGCTGCCACACGGGCCCTGGGCAACTCCAACCGAGACAAGGAAATCA
AAAGGCTAAATGAAGAAATTGAGCATCTGAGGAACAAAATGGCAGATTCAAATAGGCTAGAACG
ACAGCTGGAGGACACAGTGACACTTCGCCAAGAGCACGAGGACTCCACACACCGGCTAAAGGGC
CTAGAAAAGCAGTACCGACTGGCGCGGCAGGAGAAGGAGGACTTCCACAAGCAATTGATTGAAG
CTTCAGAAAGATTGAAATCCCAGACCAAAGAACTCAAAGATGCCCATCAGCAGCGAAAGCGGGC
CCTGCAGGAGTTCTCGGACCTCAATGAGCGCATGGCAGAGCTCCGCTCCCAGAAACAGAAGGTG
TCCCGGCAGCTCCGGGACAAAGAGGAGGAGATGGATGGGGCCATGCAGAAGATCGACTCCCTGA
GGCAGGAGATCCGCAAATCTGAGAAGTTCAGGAAAGAGCTGGAAGTGCAGCTGGAAGACGCCCT
AGCTGAGGCCTCCAAGGAGCGCAAGCTTCGCGAGCACAGTGAGAGTTTCTGCAAGCAGATGGAG
AGCGAGCTCGAGGCCCTCAAGGTAAAGCAAGGAGGTCGAGGGTCAGGGGCCACTTTGGAACACC
AGCAAGAGATTTCCAAAATCAAATCAGAGCTGGAGAAGAAGGTCTTGTTTTATGAGGAAGAGCT
GGTCCGCCGGGAGGCGTCCCACGTGCTGGAAGTGAAGACTGTGAAGAAGGAGGTGCATGACTCC
GAAAGTCACCAGCTGGCACTGCAGAAAGAAATTTTAATGTTAAAAGACAAATTGGAAAAATCAA
AACGAGAACGGCACAGTGAGATGGAGGAGGCGATAGGCACTGTGAAAGACAAGTACGAGCGAGA
ACGGGCGATACTGTCGGAGGAGAACAAGAAGCTAACTGCTGAGAATGAAAAGCTCTGTGCCTTT
GTGGATAAGCTCACAGCCCAGAACAGACAGCTGGAGGATGAGCTGCAGGATCTGGCAGCCAAGA
AGGAGTCAGTGGCACACTGGGAAGCTCAGATTGCAGAGATCATTCAGTGGGTTAGTGACGAGAA
AGATGCCCGGGGTTATCTTCAAGCCCTGGCCTCTAAGATGACTGAAGAGCTCGAGACTTTGAGG
AGTTCTAGTCTGGGATCAAGAACACTGGACCCACTTTGGAAAGTTCGCCGTAGCCAGAAACTGG
ACATGTCTGCACGGCTAGAACTGCAGTCTGCCCTTGAGGCGGAGATCCGTGCCAAGCAGCTCAT
CCAGGAAGAACTGAGGAAGGTCAAAGACACCAATCTCTCCTTTGAAAGTAAACTAAAGGATTCT
GAAGCCAAAAACAGAGAATTACTAGAAGAAATGGAAATTCTGAAGAAAAAGATGGAAGAAAAAT
TTAGAGCAGATACCGGGCTCAAGCTTCCAGATTTTCAGGATTCCATTTTCGAGTATTTCAACAC
TGCACCTCTTGCACATGACCTGACATTTAGAACTAGTTCAGCCAGTGAGCAAGAAGCACAGGCG
CCAAAGACAGAAGTATCCCCATCAGTTTCTGTGGCCGCAGGCACAGAGCAGCAAGAGGACACGA
CTCGGCCCCCACAGAGGCCACCTGCTGTGTCGCTGCCCACCACACAGGCCCTCGCCCTGGCTGG
ACCAAAGCCCAAAGCTCATCAGTTCAGCATCAAGTCCTTCTCCAGCCCCACTCAGTGCAGCCAC
TGCACCTCGCTGATGGTTGGACTGATCCGCCAGGGATACGCCTGTGAGGTGTGTGCGTTTGCCT
GCCATGCGTCCTGCAGAGACAGTGCTCCCCAGGTGTGCCCCATCCCACCTGAACAGTCCAAGAG
GCCTCTTGGCGTGGATGTACAGAGAGGCATAGGAACGGCCTACAAGGGTTGTGTCAAGGTCCCA
AAGCCCACGGGGGTGAAGAAGGGATGGCAGCGGGCCTATGCTGTGGTCTGTGACTGCAAGCTCT
TTCTGTACGACCTGCCTGAGGGAAAGTCCACCCAGCCAGGCGTCGTCGCGAGCCAAGTCCTGGA
CCTCAGGGATGACGAGTTTTCAGTAAGCTCAGTCCTGGCCTCAGATGTCATCCACGCAACACGC
CGAGACATTCCCTGTATATTCAGGGTGACAGCCTCTCTCTTAGGTTCACCTGCTAAGAACAGCT
CGCTGCTCATTCTGACAGAGAATGAGAACGAGAAGAGGAAGTGGGTAGGGATCCTGGAAGGACT
CCAGTCCATCCTCCATAAAAACCGGCTCAGGAACCAGGTCGTGCACGTCCCCCAGGAAGCCTAC
GACAGCACACTGCCACTCATCAAGGCCATCCTCACTGCTGCCATCGTGGATGGAGACAGGATTG
CTGTCGGCCTGGAAGAAGGGCTCTATGTCATCGAGGTCACCCGGGATGTGATCGTCCGTGCTGC
TGATTGTAAAAAGGTGTACCAGATTGAGCTTGCACCCAAGGAGAAAATTGTCATCCTCCTCTGT
GGGCGGAACCACCACGTGCACCTCTGTCCATGGTCTTCCTTTGACGGAGCAGAAGGCAACTTTG
ACATCAAGCTTCCGGAAACCAAGGGCTGCCAGCTTATAGCCACCGCGACTCTAAGAAAGAGCTC
CTCCACCTGTTTGTTTGTTGCGGTGAAGCGGCTGGTCCTCTGCTACGAGATCCAGAGAACTAAG
CCTTTCCACAGGAAGTTCAGTGAGCTGGTGGCTCCGGGACATGTGCAGTGGATGGCCGTGTTCA
AGGACAGGCTCTGTGTCGGCTACCCTTCTGGGTTCTCTCTGTTGAGCATCCAGGGGGACGGGCC
GTCTCTAGACCTGGTAAATCCCACTGACCCCTCGCTTGCGTTCCTCTCACAGCAGTCTTTCGAT
GCCCTTTGTGCTGTGGAGCTCAAAAGTGAGGAGTACCTGCTTTGCTTCAGCCACATGGGACTGT
ACGTGGACCCTCAAGGCCGGAGGTCACGCATGCAGGAGCTCATGTGGCCTGCGGCTCCTGTCGC
CTGTAGCTGCAGCGGCTCCCACGTTACCGTGTACAGTGAGTACGGCGTGGACGTCTTCGACGTG
TGCACCATGGAGTGGGTGCAGACCATCGGCCTGCGGAGGATAAGGCCCCTGAACTCTGACGGCA
GCCTCAACCTCCTTGGTTGTGAGCCTCCGCGCCTTATCTACTTCAAGAACAAGTCCTCAGGAAC
GGTCCTCAATGTGCCAGACACCTCAGACAGCAGCAAGAAGCAGATGCTCCGGACTCGAAGCAAA
CGGCGTTTTGTCTTCAAGGTGCCAGAGGAGGAGAGGCTGCAGCAGAGGCGAGAGATGCTCAGAG
ACCCAGAATTGAGGTCCAAGATGATATCCAACCCCACCAACTTCAACCACGTGGCCCACATGGG
CCCGGGCGACGGGATGCAGGTGCTCATGGACCTGCCTCTGAGTGCTGCACCGCTCACCCAGGAG
GAGAGGCCTGGCCCTGCCCCTGCCAGCCTGGCCCGGCAGCCTCCCTGCAGGAGCAAGCCCTACG
TCTCCTGGCCCTCCTCAGGTGGTCCAGAGCCTGGAGGGACCGTACCTCTGAGGAGCATGTCCGA
CCCCGACCAGGACTTTGACAAAGAGCCTGACTCGGATTCCACCAAACACTCAACTCCCTCAAAC
AGCTCCAACCCCAGCGGCCCGCCGAGCCCCAACTCGCCCCACAGGAGCCAGCTCCCCCTCGAAG
GCCTGGAGCAGCCAACCTGTGACGCCTGAGACTACCAGAGCACCACGGTGGGGTCAGGGAGCCG
GGATAGCCCCAGCATCAGTGCCAAGACTGAGCTGACCCTCCAGTGTTGTCCAAGGAAATGTAGA
TCCGTTTGTAGATATGGAGATGGAGAAAAGTCTTTATTAGAGTAATGGTCAGTTTTACACCACG
TCATGCGTGGCATAGACCAGATCTGTTTGTCTGCACAGCCGTGAGGCGACTCTTCTGTTTGCAC
ATGAAGGACCACCACACACTTCCCTCCCACCCAAAGCCAGCCGGGAAGGCTGTGGGGTGCTGCT
GGCTGCCTCAGTAGAGCCCCCTGAGAACCAGCCACTGGGGACAGCAGGCGGCTGGGGACGCAGC
CTCAGGGCCTAGTCTCTACCCTGGCTCCTGAGGCTGCGTCTGAGACCAGAGGGCAAGAGTAGGA
GCCCTGAGTCGTTCCCAGCGTCACTAGCGTTTGAGGACAGGAACGTGGAGGTCAGCTGTGGAAG
TCCTGGTGGTGACCGTGTCCCTGTGAGCAGAGTACTCTAGGTCACAGCCGTGTGGTGCCAGCAG
CACCAGCGCCACGAAGGCAGCTGCACTTCCACTTGCCACCAGGCGCCCGCCTCCTGCCACAGCC
AGCGTCACCTACAGGCACGCCCTGTGGCCTTCCCTTTCCGCCCTGCATGGAGCCCCGTGATTAG
TAGCCCGTGTGAATCACGTAGACTCGCCCAACACTCCTGCACATCAGCCCAGCTCACAGCGCGT
GACGCCTGTGCGTTTAACCTCACCCCTCTGTGTCCCGTGTTGAGTGACCAGGTCTGTGGCCCTG
TCTCACTGAGGCTTGTGATTCACTGTGGTAGCAGATGCAGCTTGTCACAGCTGGAGACTGGGCT
CCCATCTCCCACAAGGTGCGCTTGGCTGGGTGGGCACTGAGGGATGTGGCACCGCTGGCTGTCA
CACCCAGCACCTGCCTGCCCTCCCCGCCCTCCTGGGCCTCACGCTGGGCGGGCACCTGCTGGGG
GTTCTGGTTTTTACTTTTTTAATGTAAGTCTGAGTCTTTGTAATTATTGAATTGTGAGAACATT
TTTGAATAATTTACCTGTCAATAAAGCAGGAGATGGCAATTTTAATGTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005341066	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000687.3
GenBank Protein	KAG3260308	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005341066 ⟸ XM_005341009

- UniProtKB:

I3LXB0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKNTERIYAMKILNKWEMLKRAETACFREERDVLVKGDCQWITALHYAFQDENYLYLVMDYYVG
GDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSC
LKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESL
VETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENI
RNLEAPYIPDVSSPSDTSNFDVDDDVLRNAEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGS
LKSVMQSNTLTKDEDVQRDLENSLQVEAYERRIRRLEQEKLELSRKLQESTQTVQSLHAATRAL
GNSNRDKEIKRLNEEIEHLRNKMADSNRLERQLEDTVTLRQEHEDSTHRLKGLEKQYRLARQEK
EDFHKQLIEASERLKSQTKELKDAHQQRKRALQEFSDLNERMAELRSQKQKVSRQLRDKEEEMD
GAMQKIDSLRQEIRKSEKFRKELEVQLEDALAEASKERKLREHSESFCKQMESELEALKVKQGG
RGSGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKTVKKEVHDSESHQLALQKEIL
MLKDKLEKSKRERHSEMEEAIGTVKDKYERERAILSEENKKLTAENEKLCAFVDKLTAQNRQLE
DELQDLAAKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSSSLGSRTLDPL
WKVRRSQKLDMSARLELQSALEAEIRAKQLIQEELRKVKDTNLSFESKLKDSEAKNRELLEEME
ILKKKMEEKFRADTGLKLPDFQDSIFEYFNTAPLAHDLTFRTSSASEQEAQAPKTEVSPSVSVA
AGTEQQEDTTRPPQRPPAVSLPTTQALALAGPKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQG
YACEVCAFACHASCRDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGCVKVPKPTGVKKGWQRA
YAVVCDCKLFLYDLPEGKSTQPGVVASQVLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVTAS
LLGSPAKNSSLLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPQEAYDSTLPLIKAILT
AAIVDGDRIAVGLEEGLYVIEVTRDVIVRAADCKKVYQIELAPKEKIVILLCGRNHHVHLCPWS
SFDGAEGNFDIKLPETKGCQLIATATLRKSSSTCLFVAVKRLVLCYEIQRTKPFHRKFSELVAP
GHVQWMAVFKDRLCVGYPSGFSLLSIQGDGPSLDLVNPTDPSLAFLSQQSFDALCAVELKSEEY
LLCFSHMGLYVDPQGRRSRMQELMWPAAPVACSCSGSHVTVYSEYGVDVFDVCTMEWVQTIGLR
RIRPLNSDGSLNLLGCEPPRLIYFKNKSSGTVLNVPDTSDSSKKQMLRTRSKRRFVFKVPEEER
LQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAPLTQEERPGPAPASLAR
QPPCRSKPYVSWPSSGGPEPGGTVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNS
PHRSQLPLEGLEQPTCDA

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Ensembl Acc Id:

ENSSTOP00000000687 ⟸ ENSSTOT00000000766

Protein Domains

AGC-kinase C-terminal CNH CRIB PH Phorbol-ester/DAG-type Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000756	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000766.3	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.340	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
	3.30.60.20	UniProtKB/TrEMBL
	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	AGC-kinase_C	UniProtKB/TrEMBL
	C1-like_sf	UniProtKB/TrEMBL
	CNH_dom	UniProtKB/TrEMBL
	CRIB_dom	UniProtKB/TrEMBL
	DAG/PE-bd	UniProtKB/TrEMBL
	KELK	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Myotonic_dystrophy_kinase_coil	UniProtKB/TrEMBL
	PE/DAG-bd	UniProtKB/TrEMBL
	PH-like_dom_sf	UniProtKB/TrEMBL
	PH_domain	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Rho-assoc_Ser/Thr_Kinase	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
NCBI Gene	Cdc42bpb	ENTREZGENE
PANTHER	MYOTONIC DYSTROPHY S/T KINASE-RELATED	UniProtKB/TrEMBL
	PTHR22988:SF34	UniProtKB/TrEMBL
Pfam	C1_1	UniProtKB/TrEMBL
	CNH	UniProtKB/TrEMBL
	DMPK_coil	UniProtKB/TrEMBL
	KELK	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PRINTS	DAGPEDOMAIN	UniProtKB/TrEMBL
PROSITE	AGC_KINASE_CTER	UniProtKB/TrEMBL
	CNH	UniProtKB/TrEMBL
	CRIB	UniProtKB/TrEMBL
	PH_DOMAIN	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
	ZF_DAG_PE_1	UniProtKB/TrEMBL
	ZF_DAG_PE_2	UniProtKB/TrEMBL
SMART	CNH	UniProtKB/TrEMBL
	PBD	UniProtKB/TrEMBL
	S_TK_X	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
	SM00109	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
	SSF57889	UniProtKB/TrEMBL
UniProt	I3LXB0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM