POLR1A (RNA polymerase I subunit A) - Rat Genome Database

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Gene: POLR1A (RNA polymerase I subunit A) Chlorocebus sabaeus
Analyze
Symbol: POLR1A
Name: RNA polymerase I subunit A
RGD ID: 18662020
Description: ENCODES a protein that exhibits DNA-directed 5'-3' RNA polymerase activity (ortholog); INVOLVED IN rRNA transcription (ortholog); PARTICIPATES IN nucleotide excision repair pathway; RNA polymerase I transcription pathway; ASSOCIATED WITH acrofacial dysostosis Cincinnati type (ortholog); CD8 Deficiency, Familial (ortholog); genetic disease (ortholog); FOUND IN RNA polymerase I complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA-directed RNA polymerase I subunit RPA1; polymerase (RNA) I polypeptide A, 194kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,050,526 - 21,127,010 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1421,050,799 - 21,125,990 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604591,355,366 - 91,437,424 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
POLR1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,050,526 - 21,127,010 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1421,050,799 - 21,125,990 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604591,355,366 - 91,437,424 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
POLR1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38286,020,216 - 86,105,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl286,020,216 - 86,106,155 (-)EnsemblGRCh38hg38GRCh38
GRCh37286,247,339 - 86,333,009 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36286,106,962 - 86,186,789 (-)NCBINCBI36Build 36hg18NCBI36
Build 34286,166,037 - 86,244,626NCBI
Celera286,081,632 - 86,161,424 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef286,150,981 - 86,230,775 (-)NCBIHuRef
CHM1_1286,182,963 - 86,262,735 (-)NCBICHM1_1
T2T-CHM13v2.0286,022,315 - 86,107,956 (-)NCBIT2T-CHM13v2.0
Polr1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,886,037 - 71,956,419 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl671,886,037 - 71,961,919 (+)EnsemblGRCm39 Ensembl
GRCm38671,909,053 - 71,979,435 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,909,053 - 71,984,935 (+)EnsemblGRCm38mm10GRCm38
MGSCv37671,859,047 - 71,929,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36671,838,582 - 71,908,869 (+)NCBIMGSCv36mm8
Celera673,992,680 - 74,063,054 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.21NCBI
Polr1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84105,508,305 - 105,572,272 (+)NCBIGRCr8
mRatBN7.24103,950,051 - 104,014,022 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,950,051 - 104,014,020 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4109,329,917 - 109,393,831 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04105,105,033 - 105,168,947 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04103,719,955 - 103,783,923 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,822,964 - 99,903,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,823,252 - 99,887,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04164,601,148 - 164,665,022 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,187,426 - 105,251,385 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14105,431,906 - 105,495,866 (+)NCBI
Celera493,106,344 - 93,170,325 (+)NCBICelera
Cytogenetic Map4q32NCBI
Polr1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554241,508,037 - 1,593,108 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554241,507,935 - 1,595,068 (+)NCBIChiLan1.0ChiLan1.0
POLR1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21240,277,726 - 40,365,224 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A40,280,716 - 40,361,804 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A86,070,160 - 86,157,606 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A87,618,880 - 87,705,352 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A87,622,466 - 87,705,357 (-)Ensemblpanpan1.1panPan2
POLR1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,990,379 - 39,070,910 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1739,000,778 - 39,070,356 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1738,675,191 - 38,756,338 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01739,722,717 - 39,805,020 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1739,733,845 - 39,805,015 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,891,244 - 38,972,175 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,927,011 - 39,009,075 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01739,313,308 - 39,394,902 (+)NCBIUU_Cfam_GSD_1.0
Polr1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629279,467,900 - 79,527,456 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367121,331,073 - 1,389,856 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367121,331,016 - 1,390,544 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl358,667,971 - 58,750,421 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1358,670,377 - 58,750,441 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2361,529,882 - 61,609,817 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Polr1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474917,138,476 - 17,215,124 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474917,138,352 - 17,216,039 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007969992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000014344   ⟹   ENSCSAP00000012320
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1421,050,799 - 21,125,990 (+)Ensembl
RefSeq Acc Id: XM_007969992   ⟹   XP_007968183
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11421,050,526 - 21,127,010 (+)NCBI
Vero_WHO_p1.0NW_02366604591,355,366 - 91,437,424 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007968183 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012320.1
RefSeq Acc Id: XP_007968183   ⟸   XM_007969992
- UniProtKB: A0A0D9RUN1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000012320   ⟸   ENSCSAT00000014344


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016251 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014344.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.132.30 UniProtKB/TrEMBL
  1.10.274.100 UniProtKB/TrEMBL
  1.10.357.120 UniProtKB/TrEMBL
  2.40.40.20 UniProtKB/TrEMBL
  3.30.70.2850 UniProtKB/TrEMBL
  4.10.860.120 UniProtKB/TrEMBL
  6.10.250.2940 UniProtKB/TrEMBL
  RNA polymerase ii UniProtKB/TrEMBL
InterPro DNA-dir_RNA_pol1_lsu_C UniProtKB/TrEMBL
  DNA-dir_RNA_pol1_lsu_N UniProtKB/TrEMBL
  DNA-dir_RpoC_beta_prime UniProtKB/TrEMBL
  RNA_pol_asu UniProtKB/TrEMBL
  RNA_pol_N UniProtKB/TrEMBL
  RNA_pol_Rpb1_1 UniProtKB/TrEMBL
  RNA_pol_Rpb1_3 UniProtKB/TrEMBL
  RNA_pol_Rpb1_3_sf UniProtKB/TrEMBL
  RNA_pol_Rpb1_4 UniProtKB/TrEMBL
  RNA_pol_Rpb1_5 UniProtKB/TrEMBL
  RNA_pol_Rpb1_clamp_domain UniProtKB/TrEMBL
  Rpb1_funnel_sf UniProtKB/TrEMBL
KEGG Report csab:103219930 UniProtKB/TrEMBL
NCBI Gene POLR1A ENTREZGENE
PANTHER PTHR19376 UniProtKB/TrEMBL
  PTHR19376:SF11 UniProtKB/TrEMBL
Pfam RNA_pol_Rpb1_1 UniProtKB/TrEMBL
  RNA_pol_Rpb1_2 UniProtKB/TrEMBL
  RNA_pol_Rpb1_3 UniProtKB/TrEMBL
  RNA_pol_Rpb1_4 UniProtKB/TrEMBL
  RNA_pol_Rpb1_5 UniProtKB/TrEMBL
SMART RPOLA_N UniProtKB/TrEMBL
Superfamily-SCOP beta and beta-prime subunits of DNA dependent RNA-polymerase UniProtKB/TrEMBL
UniProt A0A0D9RUN1 ENTREZGENE, UniProtKB/TrEMBL