FAR2 (fatty acyl-CoA reductase 2) - Rat Genome Database

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Gene: FAR2 (fatty acyl-CoA reductase 2) Chlorocebus sabaeus
Analyze
Symbol: FAR2
Name: fatty acyl-CoA reductase 2
RGD ID: 18532184
Description: ENCODES a protein that exhibits alcohol-forming long-chain fatty acyl-CoA reductase activity (inferred); alcohol-forming very long-chain fatty acyl-CoA reductase activity (inferred); oxidoreductase activity (inferred); INVOLVED IN fatty acid derivative metabolic process (inferred); lipid metabolic process (inferred); long-chain fatty-acyl-CoA metabolic process (inferred); ASSOCIATED WITH alopecia (ortholog); dry eye syndrome (ortholog); FOUND IN membrane (inferred); peroxisomal membrane (inferred); peroxisome (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11128,869,987 - 29,049,421 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1128,987,566 - 29,046,448 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660695,985,117 - 6,176,706 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FAR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11128,869,987 - 29,049,421 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1128,987,566 - 29,046,448 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660695,985,117 - 6,176,706 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FAR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381229,149,278 - 29,335,616 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1229,149,016 - 29,341,121 (+)EnsemblGRCh38hg38GRCh38
GRCh371229,302,211 - 29,488,549 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361229,267,865 - 29,378,273 (+)NCBINCBI36Build 36hg18NCBI36
Build 341229,267,864 - 29,378,272NCBI
Celera1234,522,215 - 34,632,754 (+)NCBICelera
Cytogenetic Map12p11.22NCBI
HuRef1229,070,510 - 29,257,494 (+)NCBIHuRef
CHM1_11229,267,516 - 29,454,137 (+)NCBICHM1_1
T2T-CHM13v2.01229,021,810 - 29,208,149 (+)NCBIT2T-CHM13v2.0
Far2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396147,948,914 - 148,084,256 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6147,948,757 - 148,084,256 (+)EnsemblGRCm39 Ensembl
GRCm386148,047,416 - 148,182,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6148,047,259 - 148,182,758 (+)EnsemblGRCm38mm10GRCm38
MGSCv376147,995,938 - 148,131,282 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366148,004,586 - 148,139,930 (+)NCBIMGSCv36mm8
Celera6151,079,635 - 151,214,866 (+)NCBICelera
Cytogenetic Map6G3NCBI
cM Map678.49NCBI
Far2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84182,705,499 - 182,819,290 (+)NCBIGRCr8
mRatBN7.24180,973,968 - 181,087,862 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4181,007,622 - 181,087,255 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.04182,446,400 - 182,563,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4182,483,194 - 182,565,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04246,589,572 - 246,698,456 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44185,758,904 - 185,791,596 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4169,455,254 - 169,577,917 (+)NCBICelera
Cytogenetic Map4q44NCBI
Far2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555055,585,846 - 5,663,895 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555055,585,846 - 5,724,234 (-)NCBIChiLan1.0ChiLan1.0
FAR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21067,478,866 - 67,668,709 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11267,475,260 - 67,665,013 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01256,975,589 - 57,165,923 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11259,599,063 - 59,785,139 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1259,599,063 - 59,676,543 (-)Ensemblpanpan1.1panPan2
FAR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12718,659,688 - 18,791,757 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2718,661,449 - 18,792,253 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2727,618,455 - 27,750,457 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02718,851,338 - 18,983,048 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2718,852,272 - 18,983,051 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12718,661,033 - 18,792,581 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02718,685,805 - 18,817,601 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02727,773,948 - 27,905,644 (+)NCBIUU_Cfam_GSD_1.0
Far2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494580,529,346 - 80,667,427 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367601,362,364 - 1,409,418 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367601,265,803 - 1,406,405 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl544,381,129 - 44,559,374 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1544,386,808 - 44,559,506 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2547,705,595 - 47,904,904 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Far2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247786,456,008 - 6,493,697 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247786,456,396 - 6,642,551 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000005542   ⟹   ENSCSAP00000003761
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1128,987,566 - 29,046,448 (+)Ensembl
RefSeq Acc Id: XM_037990226   ⟹   XP_037846154
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660695,985,117 - 6,176,706 (-)NCBI
RefSeq Acc Id: XM_037990227   ⟹   XP_037846155
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660695,985,117 - 6,176,696 (-)NCBI
RefSeq Acc Id: XM_037990228   ⟹   XP_037846156
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660695,987,973 - 6,176,706 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037846154 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846155 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846156 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003761.1
Ensembl Acc Id: ENSCSAP00000003761   ⟸   ENSCSAT00000005542
RefSeq Acc Id: XP_037846154   ⟸   XM_037990226
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R572 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037846155   ⟸   XM_037990227
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R572 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037846156   ⟸   XM_037990228
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R572 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007541 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005542.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro FAR UniProtKB/TrEMBL
  FAR_C UniProtKB/TrEMBL
  Male_sterile_NAD-bd UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene FAR2 ENTREZGENE
PANTHER FATTY ACYL-COA REDUCTASE 2 UniProtKB/TrEMBL
  PTHR11011 UniProtKB/TrEMBL
Pfam NAD_binding_4 UniProtKB/TrEMBL
  Sterile UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0D9R572 ENTREZGENE, UniProtKB/TrEMBL