RAD51C (RAD51 paralog C) - Rat Genome Database

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Gene: RAD51C (RAD51 paralog C) Chlorocebus sabaeus
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Symbol: RAD51C
Name: RAD51 paralog C
RGD ID: 18531625
Description: ENCODES a protein that exhibits crossover junction DNA endonuclease activity (ortholog); four-way junction DNA binding (ortholog); INVOLVED IN female meiosis sister chromatid cohesion (ortholog); male meiosis I (ortholog); reciprocal meiotic recombination (ortholog); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ASSOCIATED WITH breast cancer (ortholog); Breast Cancer, Familial (ortholog); breast carcinoma (ortholog); FOUND IN cell junction (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA repair protein RAD51 homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11634,666,934 - 34,708,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1634,666,162 - 34,708,457 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660775,470,623 - 5,519,489 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAD51C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11634,666,934 - 34,708,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1634,666,162 - 34,708,457 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660775,470,623 - 5,519,489 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAD51C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381758,692,573 - 58,735,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1758,692,573 - 58,735,611 (+)EnsemblGRCh38hg38GRCh38
GRCh371756,769,934 - 56,812,972 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361754,124,962 - 54,166,691 (+)NCBINCBI36Build 36hg18NCBI36
Build 341754,124,961 - 54,166,685NCBI
Celera1753,231,717 - 53,273,527 (+)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1752,130,436 - 52,172,218 (+)NCBIHuRef
CHM1_11756,835,470 - 56,877,217 (+)NCBICHM1_1
T2T-CHM13v2.01759,560,405 - 59,603,693 (+)NCBIT2T-CHM13v2.0
Rad51c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,267,471 - 87,295,780 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,267,471 - 87,295,780 (-)EnsemblGRCm39 Ensembl
GRCm381187,376,645 - 87,404,954 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,376,645 - 87,404,954 (-)EnsemblGRCm38mm10GRCm38
MGSCv371187,191,109 - 87,217,997 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,192,840 - 87,220,634 (-)NCBIMGSCv36mm8
Celera1196,979,493 - 97,006,381 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.08NCBI
Rad51c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81072,702,299 - 72,728,980 (-)NCBIGRCr8
mRatBN7.21072,205,032 - 72,231,643 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,205,032 - 72,231,248 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1076,815,543 - 76,841,717 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01076,320,458 - 76,346,632 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01071,784,976 - 71,811,148 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01074,697,713 - 74,724,004 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1074,697,716 - 74,724,472 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01075,376,876 - 75,403,188 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41075,692,205 - 75,718,369 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1071,121,557 - 71,147,722 (-)NCBICelera
Cytogenetic Map10q26NCBI
Rad51c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,145,226 - 4,178,487 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554514,053,195 - 4,178,226 (-)NCBIChiLan1.0ChiLan1.0
RAD51C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21974,865,211 - 74,905,901 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11779,676,584 - 79,717,351 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01752,769,446 - 52,808,467 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11757,621,552 - 57,658,920 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1757,621,552 - 57,660,701 (+)Ensemblpanpan1.1panPan2
RAD51C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1933,289,675 - 33,347,411 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl933,289,742 - 33,326,405 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha932,524,483 - 32,581,843 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0934,095,493 - 34,153,075 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl934,095,486 - 34,132,470 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1932,882,005 - 32,939,352 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0933,171,057 - 33,228,397 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0933,257,474 - 33,314,872 (+)NCBIUU_Cfam_GSD_1.0
Rad51c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560232,601,741 - 32,634,425 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364904,439,097 - 4,473,357 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364904,440,638 - 4,473,301 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD51C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,975,957 - 35,019,016 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,975,949 - 35,018,112 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21235,750,071 - 35,786,767 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rad51c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624871708,048 - 746,753 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000003850   ⟹   ENSCSAP00000002121
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1634,666,162 - 34,708,457 (-)Ensembl
RefSeq Acc Id: XM_008011268   ⟹   XP_008009459
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11634,666,934 - 34,708,479 (-)NCBI
Vero_WHO_p1.0NW_0236660775,470,625 - 5,519,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008011269   ⟹   XP_008009460
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11634,666,934 - 34,708,479 (-)NCBI
Vero_WHO_p1.0NW_0236660775,470,623 - 5,519,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008011270   ⟹   XP_008009461
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11634,666,934 - 34,708,479 (-)NCBI
Vero_WHO_p1.0NW_0236660775,470,625 - 5,519,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008011272   ⟹   XP_008009463
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11634,666,934 - 34,708,479 (-)NCBI
Vero_WHO_p1.0NW_0236660775,470,625 - 5,519,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008011273   ⟹   XP_008009464
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11634,667,041 - 34,708,479 (-)NCBI
Vero_WHO_p1.0NW_0236660775,470,625 - 5,519,489 (-)NCBI
Sequence:
RefSeq Acc Id: XP_008009463   ⟸   XM_008011272
- Peptide Label: isoform X4
RefSeq Acc Id: XP_008009461   ⟸   XM_008011270
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008009460   ⟸   XM_008011269
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R0I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008009459   ⟸   XM_008011268
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008009464   ⟸   XM_008011273
- Peptide Label: isoform X5
Ensembl Acc Id: ENSCSAP00000002121   ⟸   ENSCSAT00000003850


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005814 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003850.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  5' to 3' exonuclease, C-terminal subdomain UniProtKB/TrEMBL
InterPro DNA_recomb/repair_Rad51_C UniProtKB/TrEMBL
  DNA_recomb/repair_RecA-like UniProtKB/TrEMBL
  HR_Repair_Mediator UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RecA_ATP-bd UniProtKB/TrEMBL
NCBI Gene RAD51C ENTREZGENE
PANTHER DNA REPAIR PROTEIN RAD51 HOMOLOG 3 UniProtKB/TrEMBL
  DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C UniProtKB/TrEMBL
Pfam Rad51 UniProtKB/TrEMBL
PIRSF Rad51 UniProtKB/TrEMBL
PROSITE RECA_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9R0I2 ENTREZGENE, UniProtKB/TrEMBL