ZFPM2 (zinc finger protein, FOG family member 2) - Rat Genome Database

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Gene: ZFPM2 (zinc finger protein, FOG family member 2) Chlorocebus sabaeus
Analyze
Symbol: ZFPM2
Name: zinc finger protein, FOG family member 2
RGD ID: 18522888
Description: ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); RNA polymerase II-specific DNA-binding transcription factor binding (inferred); INVOLVED IN anatomical structure morphogenesis (inferred); cardiac muscle tissue development (inferred); cell differentiation (inferred); ASSOCIATED WITH 46,XY sex reversal 3 (ortholog); 46,XY sex reversal 9 (ortholog); atrial heart septal defect (ortholog); FOUND IN cytoplasm (inferred); male germ cell nucleus (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger protein ZFPM2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18100,138,867 - 100,620,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603939,958,226 - 40,438,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZFPM2Green Monkey46,XY sex reversal 3  ISOZFPM2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:14517948 more ...
ZFPM2Green Monkey46,XY sex reversal 9  ISOZFPM2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:14517948 more ...
ZFPM2Green MonkeyCohen syndrome  ISOZFPM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Cohen syndromeClinVarPMID:28492532
ZFPM2Green MonkeyDiaphragmatic Hernia 3  ISOZFPM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Diaphragmatic hernia 3ClinVarPMID:14517948 more ...
ZFPM2Green Monkeydouble outlet right ventricle  ISOZFPM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Double outlet right ventricleClinVarPMID:14517948 more ...
ZFPM2Green Monkeygenetic disease  ISOZFPM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
ZFPM2Green Monkeytetralogy of Fallot  ISOZFPM2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:14517948 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZFPM2Green MonkeyDiaphragmatic Hernia  ISOZFPM2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17436238
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZFPM2Green Monkeycongenital diaphragmatic hernia  ISOZfpm2 (Mus musculus)9068941OMIM:142340 more ...MouseDO 
ZFPM2Green Monkeytricuspid atresia  ISOZfpm2 (Mus musculus)9068941OMIM:605067MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZFPM2Green Monkey46,XY sex reversal 9  ISOZFPM2 (Homo sapiens)7240710 OMIM 
ZFPM2Green MonkeyDiaphragmatic Hernia 3  ISOZFPM2 (Homo sapiens)7240710 OMIM 
ZFPM2Green Monkeytetralogy of Fallot  ISOZFPM2 (Homo sapiens)7240710 OMIM 


Biological Process
1 to 20 of 28 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZFPM2Green Monkeyanatomical structure morphogenesis involved_inIEAARBA:ARBA00026583150520179 UniProtGO_REF:0000117
ZFPM2Green Monkeycardiac muscle tissue development acts_upstream_of_or_withinIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeycell differentiation involved_inIEAARBA:ARBA00027429150520179 UniProtGO_REF:0000117
ZFPM2Green Monkeycell differentiation involved_inIEAPANTHER:PTN000311078150520179 TreeGrafterGO_REF:0000118
ZFPM2Green Monkeyembryonic organ development acts_upstream_of_or_withinIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeyfat cell differentiation involved_inIEAUniProtKB:Q8CCH7 more ...150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeyheart development acts_upstream_of_or_withinIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeyheart development involved_inIEAPANTHER:PTN000311078150520179 TreeGrafterGO_REF:0000118
ZFPM2Green Monkeyin utero embryonic development acts_upstream_of_or_withinIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeylung development acts_upstream_of_or_withinIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynegative regulation of DNA-templated transcription involved_inIEAUniProtKB:Q8WW38 and ensembl:ENSP00000384179150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynegative regulation of fat cell differentiation involved_inIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynegative regulation of female gonad development involved_inIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynegative regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q8WW38 and ensembl:ENSP00000384179150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynegative regulation of transcription by RNA polymerase II involved_inIEAPANTHER:PTN000311078150520179 TreeGrafterGO_REF:0000118
ZFPM2Green Monkeynegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeyoutflow tract septum morphogenesis involved_inIEAUniProtKB:Q8WW38 and ensembl:ENSP00000384179150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeypositive regulation of cardiac muscle cell proliferation involved_inIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeypositive regulation of DNA-templated transcription involved_inIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeypositive regulation of macromolecule biosynthetic process involved_inIEAARBA:ARBA00027412150520179 UniProtGO_REF:0000117
1 to 20 of 28 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZFPM2Green Monkeycytoplasm located_inIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeymale germ cell nucleus located_inIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynucleoplasm located_inIEAUniProtKB:Q8WW38 and ensembl:ENSP00000384179150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynucleus located_inIEAUniProtKB:Q8CCH7 and ensembl:ENSMUSP00000051335150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeynucleus located_inIEAPANTHER:PTN000311078150520179 TreeGrafterGO_REF:0000118
ZFPM2Green Monkeynucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
ZFPM2Green Monkeynucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043

Molecular Function
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ZFPM2Green MonkeyDNA binding enablesIEAUniProtKB-KW:KW-0238150520179 UniProtGO_REF:0000043
ZFPM2Green Monkeymetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
ZFPM2Green Monkeyprotein binding  ISOMta1 (Rattus norvegicus)9068941 RGDPMID:18067919 and REF_RGD_ID:2326010
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:Q99NA29068941 PMID:23836893UniProtPMID:23836893
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:P565469068941 PMID:20705609UniProtPMID:20705609
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:G5E9A7 more ...9068941 PMID:32814053IntActPMID:32814053
ZFPM2Green Monkeyprotein binding  ISOMta2 (Rattus norvegicus)9068941 RGDPMID:18067919 and REF_RGD_ID:2326010
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:P565469068941 PMID:10438528BHF-UCLPMID:10438528
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:P237699068941 PMID:20705609UniProtPMID:20705609
ZFPM2Green Monkeyprotein binding  ISONr2f2 (Rattus norvegicus)9068941 RGDPMID:25687237 and REF_RGD_ID:10401852
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:P237719068941 PMID:19723756UniProtPMID:19723756
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:P436949068941 PMID:21220346UniProtPMID:21220346
ZFPM2Green Monkeyprotein binding enablesISOUniProtKB:O433959068941 PMID:32296183IntActPMID:32296183
ZFPM2Green MonkeyRNA polymerase II-specific DNA-binding transcription factor binding enablesIEAInterPro:IPR039746150520179 InterProGO_REF:0000002
ZFPM2Green MonkeyRNA polymerase II-specific DNA-binding transcription factor binding enablesIEAUniProtKB:Q8WW38 and ensembl:ENSP00000384179150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeytranscription coactivator activity enablesIEAUniProtKB:Q8WW38 and ensembl:ENSP00000384179150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeytranscription corepressor activity enablesIEAUniProtKB:Q8CCH7 more ...150520179 EnsemblGO_REF:0000107
ZFPM2Green Monkeyzinc ion binding enablesIEAUniProtKB-KW:KW-0863150520179 UniProtGO_REF:0000043
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PMID:30032202  



ZFPM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18100,138,867 - 100,620,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603939,958,226 - 40,438,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ZFPM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388105,318,438 - 105,804,539 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8104,590,733 - 105,804,539 (+)EnsemblGRCh38hg38GRCh38
GRCh378106,330,666 - 106,816,767 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368106,400,323 - 106,885,943 (+)NCBINCBI36Build 36hg18NCBI36
Build 348106,400,322 - 106,885,941NCBI
Celera8102,518,281 - 103,003,726 (+)NCBICelera
Cytogenetic Map8q23.1NCBI
HuRef8101,532,803 - 102,138,045 (+)NCBIHuRef
CHM1_18106,371,762 - 106,857,264 (+)NCBICHM1_1
T2T-CHM13v2.08106,445,857 - 106,932,108 (+)NCBIT2T-CHM13v2.0
Zfpm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391540,518,438 - 40,967,988 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1540,518,431 - 40,967,988 (+)EnsemblGRCm39 Ensembl
GRCm381540,655,042 - 41,104,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1540,655,035 - 41,104,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371540,486,588 - 40,936,138 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361540,485,116 - 40,934,666 (+)NCBIMGSCv36mm8
Celera1541,140,194 - 41,582,164 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.74NCBI
Zfpm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8773,563,732 - 74,001,041 (+)NCBIGRCr8
mRatBN7.2771,678,658 - 72,116,209 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx773,563,335 - 73,995,149 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0775,765,841 - 76,197,677 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0775,633,940 - 76,065,769 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0779,471,277 - 79,964,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0779,491,886 - 79,976,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4776,210,472 - 76,654,443 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1776,324,843 - 76,675,169 (+)NCBI
Celera768,728,223 - 69,158,299 (+)NCBICelera
Cytogenetic Map7q31NCBI
Zfpm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541728,920,210 - 29,269,271 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541728,931,428 - 29,268,778 (+)NCBIChiLan1.0ChiLan1.0
ZFPM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27122,596,111 - 123,154,098 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1898,118,921 - 98,676,812 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08101,872,850 - 102,430,622 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18104,193,343 - 104,577,698 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8104,023,062 - 104,576,688 (+)Ensemblpanpan1.1panPan2
ZFPM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1136,435,368 - 6,796,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl136,336,794 - 6,796,322 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha136,442,921 - 6,803,153 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0136,588,050 - 7,045,717 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl136,587,518 - 7,044,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1136,451,443 - 6,811,875 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0136,571,226 - 6,931,950 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0136,646,836 - 7,007,257 (+)NCBIUU_Cfam_GSD_1.0
Zfpm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530331,006,795 - 31,431,557 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647038,432,897 - 38,857,662 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647038,432,894 - 38,857,656 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFPM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl431,606,773 - 32,094,287 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1431,607,968 - 31,996,226 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2434,232,973 - 34,242,599 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2434,441,657 - 34,641,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Zfpm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476321,388,244 - 21,707,953 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476321,388,060 - 21,708,969 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in ZFPM2
9078 total Variants






RefSeq Acc Id: XM_008001331   ⟹   XP_007999522
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.18100,138,867 - 100,620,355 (+)NCBI
Vero_WHO_p1.0NW_02366603939,958,226 - 40,438,731 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008001332   ⟹   XP_007999523
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.18100,138,867 - 100,620,355 (+)NCBI
Vero_WHO_p1.0NW_02366603939,958,226 - 40,438,731 (-)NCBI
Sequence:
Protein RefSeqs XP_007999522 (Get FASTA)   NCBI Sequence Viewer  
  XP_007999523 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008016.1
RefSeq Acc Id: XP_007999522   ⟸   XM_008001331
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007999523   ⟸   XM_008001332
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RHC7 (UniProtKB/TrEMBL)



1 to 17 of 17 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000011798 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009892.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro FOG UniProtKB/TrEMBL
  ZF_CCHC_FOG UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene ZFPM2 ENTREZGENE
PANTHER FRIEND OF GATA2-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZFPM2 UniProtKB/TrEMBL
Pfam zf-met UniProtKB/TrEMBL
PROSITE ZF_CCHC_FOG UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP beta-beta-alpha zinc fingers UniProtKB/TrEMBL
UniProt A0A0D9RHC7 ENTREZGENE, UniProtKB/TrEMBL
1 to 17 of 17 rows