WBP11 (WW domain binding protein 11) - Rat Genome Database

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Gene: WBP11 (WW domain binding protein 11) Chlorocebus sabaeus
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Symbol: WBP11
Name: WW domain binding protein 11
RGD ID: 18504667
Description: ENCODES a protein that exhibits protein phosphatase regulator activity (ortholog); INVOLVED IN RNA splicing (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 6 (ortholog); genetic disease (ortholog); VERTEBRAL, CARDIAC, TRACHEOESOPHAGEAL, RENAL, AND LIMB DEFECTS (ortholog); FOUND IN cytoplasm (ortholog); nuclear speck (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WW domain-binding protein 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,686,047 - 14,704,172 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,686,636 - 14,704,127 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606920,606,064 - 20,624,173 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11Green Monkeyautosomal dominant intellectual developmental disorder 6  ISOWBP11 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and autosomal dominant 6ClinVarPMID:28492532
WBP11Green Monkeygenetic disease  ISOWBP11 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868
WBP11Green MonkeyVERTEBRAL, CARDIAC, TRACHEOESOPHAGEAL, RENAL, AND LIMB DEFECTS  ISOWBP11 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:33276377
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11Green MonkeyVERTEBRAL, CARDIAC, TRACHEOESOPHAGEAL, RENAL, AND LIMB DEFECTS  ISOWBP11 (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11Green MonkeyRNA processing involved_inIEAInterPro:IPR019007150520179 InterProGO_REF:0000002
WBP11Green MonkeyRNA splicing acts_upstream_of_or_withinISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11Green Monkeycytoplasm located_inISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981
WBP11Green Monkeycytosol located_inIEAUniProtKB:Q9Y2W2 and ensembl:ENSP00000261167150520179 EnsemblGO_REF:0000107
WBP11Green Monkeyintracellular membrane-bounded organelle located_inIEAUniProtKB:Q9Y2W2 and ensembl:ENSP00000261167150520179 EnsemblGO_REF:0000107
WBP11Green Monkeynuclear speck located_inISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981
WBP11Green Monkeynucleolus NOT|located_inISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981
WBP11Green Monkeynucleoplasm located_inIEAUniProtKB:Q9Y2W2 and ensembl:ENSP00000261167150520179 EnsemblGO_REF:0000107
WBP11Green Monkeynucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
WBP11Green Monkeynucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
WBP11Green Monkeyspliceosomal complex part_ofIEAPANTHER:PTN000331948150520179 TreeGrafterGO_REF:0000118
1 to 9 of 9 rows

Molecular Function
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11Green Monkeyprotein binding enablesISOUniProtKB:O954009068941 PMID:16000308IntActPMID:16000308
WBP11Green Monkeyprotein binding enablesISOUniProtKB:O60828 more ...9068941 PMID:33961781IntActPMID:33961781
WBP11Green Monkeyprotein binding enablesISOUniProtKB:Q99IB8-PRO_00000456039068941 PMID:24136289IntActPMID:24136289
WBP11Green Monkeyprotein binding enablesISOUniProtKB:P62136 and UniProtKB:Q49AR29068941 PMID:28514442IntActPMID:28514442
WBP11Green Monkeyprotein binding enablesISOUniProtKB:P57075-2 more ...9068941 PMID:32296183IntActPMID:32296183
WBP11Green Monkeyprotein binding enablesISOUniProtKB:O60828 and UniProtKB:Q153659068941 PMID:16713569IntActPMID:16713569
WBP11Green Monkeyprotein binding enablesISOUniProtKB:O608289068941 PMID:27314904IntActPMID:27314904
WBP11Green Monkeyprotein binding enablesISOUniProtKB:O60828 more ...9068941 PMID:25416956IntActPMID:25416956
WBP11Green Monkeyprotein binding enablesISOUniProtKB:Q49AR2 and UniProtKB:Q96EZ89068941 PMID:16189514IntActPMID:16189514
WBP11Green Monkeyprotein binding enablesISOUniProtKB:P621369068941 PMID:22321011 more ...IntActPMID:22321011 more ...
WBP11Green Monkeyprotein binding enablesISOUniProtKB:P629939068941 PMID:21988832IntActPMID:21988832
WBP11Green Monkeyprotein binding enablesISOPR:P62137 more ...9068941 PMID:14640981MGIPMID:14640981
WBP11Green Monkeyprotein phosphatase regulator activity enablesISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981
WBP11Green MonkeyWW domain binding enablesIEAUniProtKB:Q9Y2W2 and ensembl:ENSP00000261167150520179 EnsemblGO_REF:0000107
1 to 14 of 14 rows

PMID:30032202  



WBP11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,686,047 - 14,704,172 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,686,636 - 14,704,127 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606920,606,064 - 20,624,173 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
WBP11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381214,784,582 - 14,803,478 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1214,784,582 - 14,803,486 (-)EnsemblGRCh38hg38GRCh38
GRCh371214,937,516 - 14,956,412 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361214,830,679 - 14,847,668 (-)NCBINCBI36Build 36hg18NCBI36
Build 341214,830,680 - 14,847,668NCBI
Celera1220,084,400 - 20,101,388 (-)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1214,708,868 - 14,725,858 (-)NCBIHuRef
CHM1_11214,905,505 - 14,922,494 (-)NCBICHM1_1
T2T-CHM13v2.01214,661,939 - 14,680,843 (-)NCBIT2T-CHM13v2.0
Wbp11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396136,790,652 - 136,805,214 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6136,790,652 - 136,805,231 (-)EnsemblGRCm39 Ensembl
GRCm386136,813,654 - 136,828,216 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6136,813,654 - 136,828,233 (-)EnsemblGRCm38mm10GRCm38
MGSCv376136,762,175 - 136,776,737 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366136,777,852 - 136,792,324 (-)NCBIMGSCv36mm8
Celera6139,822,906 - 139,837,714 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map666.72NCBI
Wbp11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84171,412,187 - 171,425,634 (-)NCBIGRCr8
mRatBN7.24169,680,984 - 169,694,431 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4169,680,983 - 169,694,443 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4175,975,711 - 175,989,125 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04171,757,453 - 171,770,900 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04170,381,374 - 170,394,788 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04170,772,166 - 170,785,613 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4170,772,163 - 170,810,080 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4170,154,227 - 170,186,942 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04234,414,445 - 234,427,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44173,823,936 - 173,837,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14174,069,061 - 174,082,432 (-)NCBI
Celera4158,264,513 - 158,277,960 (-)NCBICelera
Cytogenetic Map4q43NCBI
Wbp11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541311,533,303 - 11,549,067 (-)NCBIChiLan1.0ChiLan1.0
WBP11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21020,238,017 - 20,257,509 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,234,778 - 20,252,538 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01214,791,495 - 14,809,460 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11215,189,323 - 15,206,377 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,189,323 - 15,206,377 (-)Ensemblpanpan1.1panPan2
WBP11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12731,805,590 - 31,822,602 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2731,805,590 - 31,821,147 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2714,626,424 - 14,643,484 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02732,114,165 - 32,129,069 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12732,001,615 - 32,018,608 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02731,960,078 - 31,977,326 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02714,358,481 - 14,375,518 (-)NCBIUU_Cfam_GSD_1.0
Wbp11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494592,945,542 - 92,959,156 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365872,673,206 - 2,687,298 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WBP11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1557,749,948 - 57,766,788 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2561,196,695 - 61,205,103 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Wbp11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475223,220,021 - 23,235,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in WBP11
503 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20


RefSeq Transcripts XM_007967742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007967743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000006450   ⟹   ENSCSAP00000004655
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1114,686,636 - 14,704,127 (-)Ensembl
RefSeq Acc Id: XM_007967743   ⟹   XP_007965934
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11114,686,047 - 14,704,172 (-)NCBI
Vero_WHO_p1.0NW_02366606920,606,064 - 20,624,173 (+)NCBI
Sequence:
Protein RefSeqs XP_007965934 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004655
  ENSCSAP00000004655.1
RefSeq Acc Id: XP_007965934   ⟸   XM_007967743
- UniProtKB: A0A0D9R7R6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000004655   ⟸   ENSCSAT00000006450



Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000008440 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006450.1 UniProtKB/TrEMBL
InterPro WW_dom-bd_prot_11 UniProtKB/TrEMBL
NCBI Gene WBP11 ENTREZGENE
PANTHER PTHR13361 UniProtKB/TrEMBL
  WW DOMAIN-BINDING PROTEIN 11 UniProtKB/TrEMBL
Pfam Wbp11 UniProtKB/TrEMBL
UniProt A0A0D9R7R6 ENTREZGENE, UniProtKB/TrEMBL