WBP11 (WW domain binding protein 11) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: WBP11 (WW domain binding protein 11) Sus scrofa
Analyze
Symbol: WBP11
Name: WW domain binding protein 11
RGD ID: 14094168
Description: ENCODES a protein that exhibits protein phosphatase regulator activity (ortholog); WW domain binding (ortholog); INVOLVED IN RNA splicing (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 6 (ortholog); genetic disease (ortholog); VERTEBRAL, CARDIAC, TRACHEOESOPHAGEAL, RENAL, AND LIMB DEFECTS (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WW domain-binding protein 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1557,749,948 - 57,766,788 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2561,196,695 - 61,205,103 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11Pigautosomal dominant intellectual developmental disorder 6  ISOWBP11 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and autosomal dominant 6ClinVarPMID:28492532
WBP11Piggenetic disease  ISOWBP11 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868
WBP11PigVERTEBRAL, CARDIAC, TRACHEOESOPHAGEAL, RENAL, AND LIMB DEFECTS  ISOWBP11 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:33276377
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11PigVERTEBRAL, CARDIAC, TRACHEOESOPHAGEAL, RENAL, AND LIMB DEFECTS  ISOWBP11 (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11PigRNA processing involved_inIEAInterPro:IPR019007150520179 InterProGO_REF:0000002
WBP11PigRNA splicing acts_upstream_of_or_withinISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
WBP11Pigcytoplasm located_inISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981
WBP11Pigcytosol located_inISOWBP11 (Homo sapiens)9068941 HPAGO_REF:0000052
WBP11Pigintracellular membrane-bounded organelle located_inISOWBP11 (Homo sapiens)9068941 HPAGO_REF:0000052
WBP11Pignuclear speck located_inISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981
WBP11Pignucleolus NOT|located_inISOWbp11 (Mus musculus)9068941 PMID:14640981MGIPMID:14640981
WBP11Pignucleoplasm located_inISOWBP11 (Homo sapiens)9068941 HPAGO_REF:0000052
WBP11Pignucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
WBP11Pignucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044

Molecular Function
1 to 14 of 14 rows

  
1 to 14 of 14 rows

PMID:14681463   PMID:30032202  



WBP11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1557,749,948 - 57,766,788 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2561,196,695 - 61,205,103 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WBP11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381214,784,582 - 14,803,478 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1214,784,582 - 14,803,486 (-)EnsemblGRCh38hg38GRCh38
GRCh371214,937,516 - 14,956,412 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361214,830,679 - 14,847,668 (-)NCBINCBI36Build 36hg18NCBI36
Build 341214,830,680 - 14,847,668NCBI
Celera1220,084,400 - 20,101,388 (-)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1214,708,868 - 14,725,858 (-)NCBIHuRef
CHM1_11214,905,505 - 14,922,494 (-)NCBICHM1_1
T2T-CHM13v2.01214,661,939 - 14,680,843 (-)NCBIT2T-CHM13v2.0
Wbp11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396136,790,652 - 136,805,214 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6136,790,652 - 136,805,231 (-)EnsemblGRCm39 Ensembl
GRCm386136,813,654 - 136,828,216 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6136,813,654 - 136,828,233 (-)EnsemblGRCm38mm10GRCm38
MGSCv376136,762,175 - 136,776,737 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366136,777,852 - 136,792,324 (-)NCBIMGSCv36mm8
Celera6139,822,906 - 139,837,714 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map666.72NCBI
Wbp11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84171,412,187 - 171,425,634 (-)NCBIGRCr8
mRatBN7.24169,680,984 - 169,694,431 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4169,680,983 - 169,694,443 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4175,975,711 - 175,989,125 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04171,757,453 - 171,770,900 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04170,381,374 - 170,394,788 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04170,772,166 - 170,785,613 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4170,772,163 - 170,810,080 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4170,154,227 - 170,186,942 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04234,414,445 - 234,427,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44173,823,936 - 173,837,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14174,069,061 - 174,082,432 (-)NCBI
Celera4158,264,513 - 158,277,960 (-)NCBICelera
Cytogenetic Map4q43NCBI
Wbp11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541311,533,303 - 11,549,067 (-)NCBIChiLan1.0ChiLan1.0
WBP11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21020,238,017 - 20,257,509 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,234,778 - 20,252,538 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01214,791,495 - 14,809,460 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11215,189,323 - 15,206,377 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,189,323 - 15,206,377 (-)Ensemblpanpan1.1panPan2
WBP11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12731,805,590 - 31,822,602 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2731,805,590 - 31,821,147 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2714,626,424 - 14,643,484 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02732,114,165 - 32,129,069 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12732,001,615 - 32,018,608 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02731,960,078 - 31,977,326 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02714,358,481 - 14,375,518 (-)NCBIUU_Cfam_GSD_1.0
Wbp11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494592,945,542 - 92,959,156 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365872,673,206 - 2,687,298 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WBP11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,686,047 - 14,704,172 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,686,636 - 14,704,127 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606920,606,064 - 20,624,173 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wbp11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475223,220,021 - 23,235,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in WBP11
516 total Variants



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3



RefSeq Acc Id: XM_003481683   ⟹   XP_003481731
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1557,749,948 - 57,766,788 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003481731   ⟸   XM_003481683
- UniProtKB: A0A5G2QEI2 (UniProtKB/TrEMBL),   A0A8D0S9U9 (UniProtKB/TrEMBL),   A0A0B8RS58 (UniProtKB/TrEMBL),   A0A8D2AB61 (UniProtKB/TrEMBL)
- Sequence:



1 to 40 of 44 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000000611 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015019738 UniProtKB/TrEMBL
  ENSSSCG00025047494 UniProtKB/TrEMBL
  ENSSSCG00030053222 UniProtKB/TrEMBL
  ENSSSCG00035045700 UniProtKB/TrEMBL
  ENSSSCG00040058754 UniProtKB/TrEMBL
  ENSSSCG00045021135 UniProtKB/TrEMBL
  ENSSSCG00050041473 UniProtKB/TrEMBL
  ENSSSCG00055014199 UniProtKB/TrEMBL
  ENSSSCG00060000267 UniProtKB/TrEMBL
  ENSSSCG00065077601 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000657.5 UniProtKB/TrEMBL
  ENSSSCT00000077022 ENTREZGENE
  ENSSSCT00000077022.1 UniProtKB/TrEMBL
  ENSSSCT00015026231.1 UniProtKB/TrEMBL
  ENSSSCT00025064670.1 UniProtKB/TrEMBL
  ENSSSCT00025064847.1 UniProtKB/TrEMBL
  ENSSSCT00030074279.1 UniProtKB/TrEMBL
  ENSSSCT00030074291.1 UniProtKB/TrEMBL
  ENSSSCT00035060748.1 UniProtKB/TrEMBL
  ENSSSCT00040079826.1 UniProtKB/TrEMBL
  ENSSSCT00040079878.1 UniProtKB/TrEMBL
  ENSSSCT00045036048.1 UniProtKB/TrEMBL
  ENSSSCT00045036157.1 UniProtKB/TrEMBL
  ENSSSCT00050056253.1 UniProtKB/TrEMBL
  ENSSSCT00055028087.1 UniProtKB/TrEMBL
  ENSSSCT00055028156.1 UniProtKB/TrEMBL
  ENSSSCT00060000286.1 UniProtKB/TrEMBL
  ENSSSCT00060000291.1 UniProtKB/TrEMBL
  ENSSSCT00065107381.1 UniProtKB/TrEMBL
  ENSSSCT00065107394.1 UniProtKB/TrEMBL
InterPro WW_dom-bd_prot_11 UniProtKB/TrEMBL
KEGG Report ssc:100739009 UniProtKB/TrEMBL
NCBI Gene WBP11 ENTREZGENE
PANTHER PTHR13361 UniProtKB/TrEMBL
  WW DOMAIN-BINDING PROTEIN 11 UniProtKB/TrEMBL
Pfam Wbp11 UniProtKB/TrEMBL
UniProt A0A0B8RS58 ENTREZGENE
  A0A5G2QEI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LKA9_PIG UniProtKB/TrEMBL
1 to 40 of 44 rows