INSL3 (insulin like 3) - Rat Genome Database

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Gene: INSL3 (insulin like 3) Chlorocebus sabaeus
Analyze
Symbol: INSL3
Name: insulin like 3
RGD ID: 18407399
Description: ENCODES a protein that exhibits G protein-coupled receptor binding (inferred); hormone activity (inferred); protease binding (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); in utero embryonic development (ortholog); male gonad development (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); genetic disease (ortholog); Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 (ortholog); FOUND IN extracellular space (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: insulin-like 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,291,220 - 16,296,705 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,291,563 - 16,296,643 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660743,092,222 - 3,097,819 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
INSL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,291,220 - 16,296,705 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,291,563 - 16,296,643 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660743,092,222 - 3,097,819 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
INSL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381917,816,512 - 17,821,519 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1917,816,512 - 17,821,574 (-)EnsemblGRCh38hg38GRCh38
GRCh371917,927,321 - 17,932,328 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,788,322 - 17,793,320 (-)NCBINCBI36Build 36hg18NCBI36
Build 341917,788,321 - 17,793,320NCBI
Celera1917,829,042 - 17,834,041 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,492,756 - 17,497,784 (-)NCBIHuRef
CHM1_11917,926,865 - 17,931,926 (-)NCBICHM1_1
T2T-CHM13v2.01917,950,620 - 17,955,630 (-)NCBIT2T-CHM13v2.0
Insl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,141,896 - 72,143,221 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl872,141,858 - 72,143,219 (+)EnsemblGRCm39 Ensembl
GRCm38871,689,252 - 71,690,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,689,214 - 71,690,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv37874,213,151 - 74,214,474 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36874,618,241 - 74,619,564 (+)NCBIMGSCv36mm8
Celera874,203,798 - 74,205,121 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.43NCBI
Insl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,432,668 - 18,434,539 (+)NCBIGRCr8
mRatBN7.21618,398,682 - 18,400,566 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,384,829 - 18,400,560 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,449,855 - 18,451,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,582,466 - 19,583,809 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,502,794 - 18,504,137 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,120,753 - 20,122,702 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,121,352 - 20,122,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,981,216 - 19,983,156 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,890,131 - 18,891,475 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11618,890,128 - 18,891,473 (+)NCBI
Celera1618,601,812 - 18,603,156 (+)NCBICelera
Cytogenetic Map16p14NCBI
Insl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,413,246 - 3,416,025 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,413,764 - 3,415,691 (+)NCBIChiLan1.0ChiLan1.0
INSL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,071,128 - 45,072,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,050,526 - 45,072,805 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,983,087 - 44,984,405 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,556,269 - 45,557,587 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,535,982 - 45,557,946 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,792,679 - 44,793,993 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,202,958 - 45,204,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,478,927 - 45,480,245 (+)NCBIUU_Cfam_GSD_1.0
INSL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,929,584 - 59,931,219 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,929,591 - 59,931,220 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,499,023 - 59,500,652 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2q12-q13NCBI
Insl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249081,368,660 - 1,369,740 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
7 5 18 19 19 6 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007995748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000003517   ⟹   ENSCSAP00000001788
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl616,291,563 - 16,296,643 (-)Ensembl
RefSeq Acc Id: XM_007995748   ⟹   XP_007993939
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1616,291,220 - 16,296,705 (-)NCBI
Vero_WHO_p1.0NW_0236660743,092,222 - 3,097,819 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007993939 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001788
  ENSCSAP00000001788.1
RefSeq Acc Id: XP_007993939   ⟸   XM_007995748
- UniProtKB: A0A0D9QZJ9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001788   ⟸   ENSCSAT00000003517


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005480 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003517.1 UniProtKB/TrEMBL
Gene3D-CATH Insulin-like UniProtKB/TrEMBL
InterPro INSL3/INSL4 UniProtKB/TrEMBL
  Insulin-like UniProtKB/TrEMBL
  Insulin-like_sf UniProtKB/TrEMBL
  Insulin_CS UniProtKB/TrEMBL
KEGG Report csab:103234154 UniProtKB/TrEMBL
NCBI Gene INSL3 ENTREZGENE
PANTHER INSULIN-LIKE 3 UniProtKB/TrEMBL
  PTHR10423 UniProtKB/TrEMBL
Pfam Insulin UniProtKB/TrEMBL
PROSITE INSULIN UniProtKB/TrEMBL
SMART IlGF UniProtKB/TrEMBL
Superfamily-SCOP SSF56994 UniProtKB/TrEMBL
UniProt A0A0D9QZJ9 ENTREZGENE, UniProtKB/TrEMBL