LOC103247474 (cytokine receptor like factor 2) - Rat Genome Database

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Gene: LOC103247474 (cytokine receptor like factor 2) Chlorocebus sabaeus
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Symbol: LOC103247474
Name: cytokine receptor like factor 2
RGD ID: 18386531
Description: ENCODES a protein that exhibits cytokine activity (ortholog); INVOLVED IN inflammatory response (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); Acute Lymphoblastic Leukemia, with Lymphomatous Features (ortholog); autistic disorder (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CRLF2; cytokine receptor-like factor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_023666141213,570 - 241,034 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103247474
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_023666141213,570 - 241,034 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CRLF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y1,190,490 - 1,212,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38X1,190,490 - 1,212,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblY1,190,490 - 1,212,723 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 EnsemblX1,190,490 - 1,212,723 (-)EnsemblGRCh38hg38GRCh38
GRCh37Y1,264,869 - 1,281,542 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X1,314,869 - 1,331,542 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36Y1,274,894 - 1,291,529 (-)NCBINCBI36Build 36hg18NCBI36
Build 36X1,274,894 - 1,291,529 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX5,605,262 - 5,605,961 (-)NCBICelera
Cytogenetic MapX;YNCBI
CHM1_1X1,345,456 - 1,361,581 (-)NCBICHM1_1
T2T-CHM13v2.0X1,035,684 - 1,058,464 (-)NCBIT2T-CHM13v2.0
T2T-CHM13v2.0Y1,050,430 - 1,072,677 (-)NCBIT2T-CHM13v2.0
Crlf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395109,702,575 - 109,707,301 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5109,702,575 - 109,706,859 (-)EnsemblGRCm39 Ensembl
GRCm385109,554,709 - 109,559,128 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5109,554,709 - 109,558,993 (-)EnsemblGRCm38mm10GRCm38
MGSCv375109,983,728 - 109,988,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365109,795,011 - 109,799,248 (-)NCBIMGSCv36mm8
Celera5106,655,703 - 106,673,432 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map553.24NCBI
Crlf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814118,932 - 123,632 (+)NCBIGRCr8
mRatBN7.214103,943 - 108,643 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14103,939 - 108,642 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14121,877 - 126,551 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0141,423,652 - 1,428,326 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014120,324 - 124,998 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0141,456,843 - 1,461,543 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl141,456,844 - 1,461,543 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0141,459,624 - 1,464,324 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera14656,303 - 661,003 (-)NCBICelera
Cytogenetic Map14p22NCBI
Crlf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955499940,250 - 955,458 (-)NCBIChiLan1.0ChiLan1.0
LOC100981146
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2Y45,865,325 - 45,891,246 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1-v2X1,030,768 - 1,056,303 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X1,034,411 - 1,060,265 (-)NCBINHGRI_mPanPan1
NHGRI_mPanPan1Y1,063,595 - 1,089,386 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X933,459 - 957,950 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CRLF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X780,924 - 801,961 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX780,711 - 802,836 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX719,633 - 740,407 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X688,940 - 709,953 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX688,660 - 710,093 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X682,055 - 702,828 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X697,563 - 718,580 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X694,446 - 715,490 (-)NCBIUU_Cfam_GSD_1.0
Crlf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404953503,508 - 509,770 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366443,866,973 - 3,872,749 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRLF2
(Sus scrofa - pig)
No map positions available.
Crlf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624834596,067 - 610,333 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
37 25 20 33 33 24 12

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_037995549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_037995549   ⟹   XP_037851477
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666141213,570 - 241,034 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037851477 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014386.1
RefSeq Acc Id: XP_037851477   ⟸   XM_037995549
- UniProtKB: A0A0D9S0J7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018376 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016477.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CRLF2-like_D2 UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  TSLPR_D1 UniProtKB/TrEMBL
NCBI Gene CRLF2 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  CYTOKINE RECEPTOR-LIKE FACTOR 2-RELATED UniProtKB/TrEMBL
Pfam CRLF2-like_D2 UniProtKB/TrEMBL
  TSLPR_D1 UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
UniProt A0A0D9S0J7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103247474  cytokine receptor like factor 2  CRLF2  cytokine receptor like factor 2  Symbol and/or name change 5135510 APPROVED