RHBDF1 (rhomboid 5 homolog 1) - Rat Genome Database

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Gene: RHBDF1 (rhomboid 5 homolog 1) Chlorocebus sabaeus
Analyze
Symbol: RHBDF1
Name: rhomboid 5 homolog 1
RGD ID: 18359274
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN cell migration (inferred); cell population proliferation (inferred); negative regulation of protein secretion (inferred); ASSOCIATED WITH familial focal epilepsy with variable foci 3 (ortholog); Wolff-Parkinson-White syndrome (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive rhomboid protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1514,935 - 34,991 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl513,071 - 21,883 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606831,194,498 - 31,209,982 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RHBDF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1514,935 - 34,991 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl513,071 - 21,883 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606831,194,498 - 31,209,982 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RHBDF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381658,059 - 76,360 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1658,059 - 76,355 (-)EnsemblGRCh38hg38GRCh38
GRCh3716108,058 - 122,629 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361648,058 - 62,591 (-)NCBINCBI36Build 36hg18NCBI36
Build 341648,058 - 62,591NCBI
Celera16309,954 - 324,535 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef1626,451 - 41,032 (-)NCBIHuRef
CHM1_116107,996 - 122,575 (-)NCBICHM1_1
T2T-CHM13v2.01651,596 - 69,903 (-)NCBIT2T-CHM13v2.0
Rhbdf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,159,585 - 32,172,339 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,159,585 - 32,172,300 (-)EnsemblGRCm39 Ensembl
GRCm381132,209,585 - 32,222,331 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,209,585 - 32,222,300 (-)EnsemblGRCm38mm10GRCm38
MGSCv371132,109,585 - 32,122,293 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,109,585 - 32,122,238 (-)NCBIMGSCv36mm8
Celera1134,626,680 - 34,639,569 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.83NCBI
Rhbdf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,911,282 - 15,924,214 (+)NCBIGRCr8
mRatBN7.21015,406,832 - 15,419,765 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,406,859 - 15,419,763 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1020,152,893 - 20,165,784 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,641,781 - 19,654,677 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01015,134,664 - 15,147,558 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,672,370 - 15,685,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,672,382 - 15,685,284 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,567,515 - 15,580,428 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,653,948 - 15,666,851 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,661,089 - 15,667,673 (+)NCBI
Celera1015,074,361 - 15,087,252 (+)NCBICelera
Cytogenetic Map10q12NCBI
Rhbdf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,078,864 - 17,098,999 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,090,962 - 17,098,068 (+)NCBIChiLan1.0ChiLan1.0
RHBDF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218273,273 - 291,700 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,065,373 - 4,083,718 (-)NCBINHGRI_mPanPan1
PanPan1.11649,031 - 57,211 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1649,031 - 57,222 (-)Ensemblpanpan1.1panPan2
RHBDF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,394,654 - 40,413,619 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,395,517 - 40,413,606 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,652,775 - 41,676,636 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,732,787 - 40,756,647 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,739,139 - 40,756,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1640,420,352 - 40,444,203 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,381,279 - 40,405,130 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,860,455 - 40,884,315 (+)NCBIUU_Cfam_GSD_1.0
Rhbdf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,705,206 - 112,712,074 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501803,005 - 813,367 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501802,728 - 810,375 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHBDF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,560,915 - 41,567,593 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,548,440 - 41,567,596 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,869,445 - 40,888,436 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rhbdf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913937,484 - 954,428 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913937,484 - 954,458 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RHBDF1
386 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000011242   ⟹   ENSCSAP00000009322
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl513,071 - 21,883 (-)Ensembl
RefSeq Acc Id: XM_007980011   ⟹   XP_007978202
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1514,935 - 30,119 (-)NCBI
Vero_WHO_p1.0NW_02366606831,194,498 - 31,209,982 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037990089   ⟹   XP_037846017
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606831,194,498 - 31,209,982 (+)NCBI
RefSeq Acc Id: XM_037990090   ⟹   XP_037846018
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606831,196,427 - 31,209,982 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007978202 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846017 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846018 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009322.1
RefSeq Acc Id: XP_007978202   ⟸   XM_007980011
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RL33 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000009322   ⟸   ENSCSAT00000011242
RefSeq Acc Id: XP_037846017   ⟸   XM_037990089
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037846018   ⟸   XM_037990090
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013151 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011242.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1540.10 UniProtKB/TrEMBL
InterPro Inactive_Rhomboid UniProtKB/TrEMBL
  Peptidase_S54_rhomboid_dom UniProtKB/TrEMBL
  Rhomboid-like_sf UniProtKB/TrEMBL
  Rhomboid_SP UniProtKB/TrEMBL
NCBI Gene RHBDF1 ENTREZGENE
PANTHER INACTIVE RHOMBOID PROTEIN UniProtKB/TrEMBL
  INACTIVE RHOMBOID PROTEIN 1 UniProtKB/TrEMBL
Pfam Rhomboid UniProtKB/TrEMBL
  Rhomboid_SP UniProtKB/TrEMBL
Superfamily-SCOP SSF144091 UniProtKB/TrEMBL
UniProt A0A0D9RL33 ENTREZGENE, UniProtKB/TrEMBL