Cd55b (CD55 molecule, decay accelerating factor for complement B) - Rat Genome Database
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Gene: Cd55b (CD55 molecule, decay accelerating factor for complement B) Mus musculus
Analyze
No known orthologs.
Symbol: Cd55b
Name: CD55 molecule, decay accelerating factor for complement B
RGD ID: 1623314
MGI Page MGI
Description: Predicted to have enzyme inhibitor activity; lipid binding activity; and virus receptor activity. Predicted to be involved in complement activation, classical pathway and innate immune response. Predicted to localize to apical plasma membrane; cell surface; and membrane raft. Is expressed in several structures, including alimentary system; metanephros; olfactory epithelium; respiratory system; and trigeminal ganglion. Human ortholog(s) of this gene implicated in prostate cancer and protein-losing enteropathy. Orthologous to human CD55 (CD55 molecule (Cromer blood group)).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI323748; complement decay-accelerating factor transmembrane isoform; complement-transmembrane; Daf; Daf-T; Daf-TM; Daf2; decay accelerating factor 2; MGC156369; TM-DA; TM-DAF
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,316,263 - 130,350,831 (-)NCBIGRCm39mm39
GRCm381130,388,526 - 130,423,097 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,388,537 - 130,423,009 (-)EnsemblGRCm38mm10GRCm38
MGSCv371132,285,105 - 132,319,576 (-)NCBIGRCm37mm9NCBIm37
MGSCv361132,216,072 - 132,250,555 (-)NCBImm8
Celera1133,017,026 - 133,051,496 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:7545711   PMID:9435343   PMID:9892684   PMID:10349636   PMID:10417349   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073  
PMID:16517735   PMID:17287827   PMID:21267068   PMID:21677750  


Genomics

Position Markers
AI323748  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381130,461,850 - 130,461,933UniSTSGRCm38
GRCm381130,422,143 - 130,422,226UniSTSGRCm38
MGSCv371132,318,720 - 132,318,803UniSTSGRCm37
MGSCv371132,358,427 - 132,358,510UniSTSGRCm37
Celera1133,050,640 - 133,050,723UniSTS
Celera1133,090,318 - 133,090,401UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
cM Map167.6UniSTS
Whitehead/MRC_RH11722.0UniSTS
AW552990  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381130,389,768 - 130,389,898UniSTSGRCm38
MGSCv371132,286,345 - 132,286,475UniSTSGRCm37
Celera1133,018,266 - 133,018,396UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
Whitehead/MRC_RH10974.86UniSTS
BB285655  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381130,437,672 - 130,437,817UniSTSGRCm38
MGSCv371132,334,249 - 132,334,394UniSTSGRCm37
Celera1133,066,166 - 133,066,311UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
Whitehead/MRC_RH11722.77UniSTS
C87253  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381130,439,126 - 130,439,341UniSTSGRCm38
GRCm381130,390,162 - 130,390,376UniSTSGRCm38
MGSCv371132,286,739 - 132,286,953UniSTSGRCm37
MGSCv371132,335,703 - 132,335,918UniSTSGRCm37
Celera1133,018,660 - 133,018,874UniSTS
Celera1133,067,620 - 133,067,835UniSTS
Cytogenetic Map1E4UniSTS
cM Map167.6UniSTS
cM Map167.6UniSTS
Whitehead/MRC_RH11719.05UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74477076148839837Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174952818133363199Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)176000000148900000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782314261147249632Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182665468135687641Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194200000148900000Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195600000162200000Mouse
1301123Cd8mts2_mCD8 memory T cell subset 2 (mouse)Not determined196690656130690827Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197126256131126460Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199579930133580115Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1103040804137040937Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109568206143568206Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109710525143710742Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110625442144625561Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110625442144625561Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112203268146203348Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116363098150363199Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118171982152172078Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121800000139800000Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121800000153900000Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121800000154000000Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1123000000157000000Mouse
1301488Tir3b_mtrypansomiasis infection response 3b (mouse)Not determined1128551097157361794Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129255120163255255Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:214
Count of miRNA genes:118
Interacting mature miRNAs:119
Transcripts:ENSMUST00000112488, ENSMUST00000119432, ENSMUST00000136497
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001317361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017314396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB003321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC111067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC116692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF143540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI326546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ046619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ236680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU222534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L41365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L41500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000112488   ⟹   ENSMUSP00000108107
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1130,388,537 - 130,423,009 (-)Ensembl
RefSeq Acc Id: ENSMUST00000119432   ⟹   ENSMUSP00000113352
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1130,388,537 - 130,423,009 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136497
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1130,419,601 - 130,422,740 (-)Ensembl
RefSeq Acc Id: NM_001317361   ⟹   NP_001304290
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,316,265 - 130,350,780 (-)NCBI
GRCm381130,388,528 - 130,423,043 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007827   ⟹   NP_031853
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,316,265 - 130,350,780 (-)NCBI
GRCm381130,388,528 - 130,423,043 (-)NCBI
MGSCv371132,285,105 - 132,319,576 (-)RGD
Celera1133,017,026 - 133,051,496 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011247917   ⟹   XP_011246219
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,319,126 - 130,350,829 (-)NCBI
GRCm381130,391,389 - 130,423,095 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017314396   ⟹   XP_017169885
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,316,263 - 130,350,831 (-)NCBI
GRCm381130,388,526 - 130,423,097 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246278   ⟹   XP_030102138
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,316,263 - 130,350,535 (-)NCBI
GRCm381130,388,526 - 130,422,802 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246295   ⟹   XP_030102155
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,319,126 - 130,350,534 (-)NCBI
GRCm381130,391,389 - 130,422,801 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_031853   ⟸   NM_007827
- Peptide Label: isoform 1 precursor
- UniProtKB: Q61476 (UniProtKB/Swiss-Prot),   E9QAP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246219   ⟸   XM_011247917
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169885   ⟸   XM_017314396
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001304290   ⟸   NM_001317361
- Peptide Label: isoform 2 precursor
- UniProtKB: Q61476 (UniProtKB/Swiss-Prot),   E9Q731 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030102138   ⟸   XM_030246278
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030102155   ⟸   XM_030246295
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000113352   ⟸   ENSMUST00000119432
RefSeq Acc Id: ENSMUSP00000108107   ⟸   ENSMUST00000112488
Protein Domains
Sushi

Promoters
RGD ID:6874812
Promoter ID:EPDNEW_M857
Type:initiation region
Name:Cd55b_1
Description:Mus musculus CD55 molecule, decay accelerating factor for complementB , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381130,423,043 - 130,423,103EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104849 AgrOrtholog
Ensembl Genes ENSMUSG00000026401 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000108107 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000113352 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112488 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000119432 ENTREZGENE, UniProtKB/TrEMBL
InterPro Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13137 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:104849 ENTREZGENE
NCBI Gene 13137 ENTREZGENE
Pfam Sushi UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cd55b PhenoGen
PROSITE SUSHI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CCP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57535 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0JP41_MOUSE UniProtKB/TrEMBL
  DAF2_MOUSE UniProtKB/Swiss-Prot
  E9Q731 ENTREZGENE, UniProtKB/TrEMBL
  E9QAP4 ENTREZGENE, UniProtKB/TrEMBL
  Q61476 ENTREZGENE
  Q9R1C2_MOUSE UniProtKB/TrEMBL
UniProt Secondary E9QLT3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-30 Cd55b  CD55 molecule, decay accelerating factor for complement B  Daf2  decay accelerating factor 2  Symbol and/or name change 5135510 APPROVED