B3gnt8 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8) - Rat Genome Database

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Gene: B3gnt8 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8) Mus musculus
Analyze
Symbol: B3gnt8
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
RGD ID: 1622061
MGI Page MGI
Description: Predicted to enable protein N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to be active in Golgi membrane. Is expressed in alimentary system; integumental system; nervous system; and nucleus pulposus. Orthologous to human B3GNT8 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B3gal; B3galt7; B7galt7; BC025206; beta-1,3-Gn-T8; beta-1,3-N-acetylglucosaminyltransferase 8; beta3Gn-T8; BGnT-8; MGC32391; UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,327,025 - 25,328,917 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl725,326,079 - 25,334,525 (+)EnsemblGRCm39 Ensembl
GRCm38725,627,600 - 25,629,492 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,626,654 - 25,635,100 (+)EnsemblGRCm38mm10GRCm38
MGSCv37726,412,643 - 26,414,509 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36725,336,384 - 25,338,252 (+)NCBIMGSCv36mm8
Celera720,236,645 - 20,238,511 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14681479   PMID:16141072   PMID:16141073   PMID:18826941   PMID:21267068   PMID:21873635  
PMID:27480124  


Genomics

Comparative Map Data
B3gnt8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,327,025 - 25,328,917 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl725,326,079 - 25,334,525 (+)EnsemblGRCm39 Ensembl
GRCm38725,627,600 - 25,629,492 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,626,654 - 25,635,100 (+)EnsemblGRCm38mm10GRCm38
MGSCv37726,412,643 - 26,414,509 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36725,336,384 - 25,338,252 (+)NCBIMGSCv36mm8
Celera720,236,645 - 20,238,511 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.94NCBI
B3GNT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,425,359 - 41,428,730 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1941,425,359 - 41,428,730 (-)EnsemblGRCh38hg38GRCh38
GRCh371941,931,264 - 41,934,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361946,623,104 - 46,626,475 (-)NCBINCBI36Build 36hg18NCBI36
Build 341946,623,104 - 46,626,475NCBI
Celera1938,731,099 - 38,734,479 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1938,363,040 - 38,366,420 (-)NCBIHuRef
CHM1_11941,930,949 - 41,934,320 (-)NCBICHM1_1
T2T-CHM13v2.01944,246,583 - 44,249,963 (-)NCBIT2T-CHM13v2.0
B3gnt8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8190,263,387 - 90,266,292 (+)NCBIGRCr8
mRatBN7.2181,135,602 - 81,138,501 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl181,135,499 - 81,142,263 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx186,527,798 - 86,530,697 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0195,079,711 - 95,082,610 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0188,283,593 - 88,286,492 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0182,419,264 - 82,422,852 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,419,947 - 82,422,846 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,681,429 - 83,684,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,834,562 - 80,837,461 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1180,912,258 - 80,915,413 (+)NCBI
Celera175,575,956 - 75,578,855 (+)NCBICelera
Cytogenetic Map1q21NCBI
B3gnt8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555357,726 - 359,695 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955555357,726 - 359,695 (-)NCBIChiLan1.0ChiLan1.0
B3GNT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22047,636,090 - 47,641,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11949,504,977 - 49,508,261 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01938,419,180 - 38,422,360 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11946,925,525 - 46,927,751 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,925,762 - 46,926,955 (-)Ensemblpanpan1.1panPan2
B3GNT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,576,992 - 112,579,104 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,981,161 - 111,983,281 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,175,082 - 113,177,202 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,175,624 - 113,179,353 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,736,370 - 112,738,490 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,368,713 - 112,370,834 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,361,967 - 113,364,087 (+)NCBIUU_Cfam_GSD_1.0
B3gnt8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,389,477 - 15,391,823 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366613,818,120 - 3,819,307 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366613,817,791 - 3,819,854 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B3GNT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,399,123 - 49,402,661 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,399,121 - 49,403,686 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,230,322 - 45,234,561 (+)NCBISscrofa10.2Sscrofa10.2susScr3
B3GNT8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,747,599 - 35,751,265 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl635,747,833 - 35,749,026 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607313,983,730 - 13,986,454 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
B3gnt8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907225,888 - 227,081 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907225,662 - 227,649 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in B3gnt8
88 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:116
Interacting mature miRNAs:124
Transcripts:ENSMUST00000076034
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse

Markers in Region
Bckdha  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38725,630,254 - 25,631,074UniSTSGRCm38
MGSCv37726,415,273 - 26,416,093UniSTSGRCm37
Celera720,239,275 - 20,240,095UniSTS
Cytogenetic Map7A3UniSTS
cM MapUN UniSTS
cM Map7 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000076034   ⟹   ENSMUSP00000092277
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,327,063 - 25,328,917 (+)Ensembl
GRCm38.p6 Ensembl725,627,638 - 25,629,492 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205281   ⟹   ENSMUSP00000146127
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,326,079 - 25,327,850 (+)Ensembl
GRCm38.p6 Ensembl725,626,654 - 25,628,425 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206824
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,327,067 - 25,328,910 (+)Ensembl
GRCm38.p6 Ensembl725,627,642 - 25,629,485 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206940   ⟹   ENSMUSP00000145797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl725,327,062 - 25,334,525 (+)Ensembl
GRCm38.p6 Ensembl725,627,637 - 25,635,100 (+)Ensembl
RefSeq Acc Id: NM_001036740   ⟹   NP_001031817
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,327,049 - 25,328,915 (+)NCBI
GRCm38725,627,624 - 25,629,490 (+)NCBI
MGSCv37726,412,643 - 26,414,509 (+)RGD
Celera720,236,645 - 20,238,511 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_146184   ⟹   NP_666296
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,327,049 - 25,328,915 (+)NCBI
GRCm38725,627,624 - 25,629,490 (+)NCBI
MGSCv37726,412,643 - 26,414,509 (+)RGD
Celera720,236,645 - 20,238,511 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539853   ⟹   XP_006539916
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39725,327,025 - 25,328,917 (+)NCBI
GRCm38725,627,600 - 25,629,492 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001031817   ⟸   NM_001036740
- UniProtKB: Q8R3I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_666296   ⟸   NM_146184
- UniProtKB: Q8R3I9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539916   ⟸   XM_006539853
- Peptide Label: isoform X1
- UniProtKB: Q8R3I9 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000145797   ⟸   ENSMUST00000206940
Ensembl Acc Id: ENSMUSP00000146127   ⟸   ENSMUST00000205281
Ensembl Acc Id: ENSMUSP00000092277   ⟸   ENSMUST00000076034

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R3I9-F1-model_v2 AlphaFold Q8R3I9 1-389 view protein structure

Promoters
RGD ID:6892290
Promoter ID:EPDNEW_M9596
Type:initiation region
Name:B3gnt8_1
Description:Mus musculus UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase8 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38725,627,611 - 25,627,671EPDNEW
RGD ID:6840682
Promoter ID:MM_KWN:49462
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000076034,   NM_146184
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36726,411,791 - 26,414,077 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2385269 AgrOrtholog
Ensembl Genes ENSMUSG00000059479 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000076034 ENTREZGENE
  ENSMUST00000076034.8 UniProtKB/Swiss-Prot
  ENSMUST00000205281.2 UniProtKB/TrEMBL
  ENSMUST00000206824 ENTREZGENE
  ENSMUST00000206940.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.550.50 UniProtKB/Swiss-Prot
InterPro Glyco_trans_31 UniProtKB/Swiss-Prot
KEGG Report mmu:232984 UniProtKB/Swiss-Prot
MGD MGI:2385269 ENTREZGENE
NCBI Gene 232984 ENTREZGENE
PANTHER PTHR11214 UniProtKB/Swiss-Prot
  UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 8 UniProtKB/Swiss-Prot
Pfam Galactosyl_T UniProtKB/Swiss-Prot
PhenoGen B3gnt8 PhenoGen
UniProt A0A0U1RPU4_MOUSE UniProtKB/TrEMBL
  B3GN8_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE