Exoc3l2 (exocyst complex component 3-like 2) - Rat Genome Database

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Gene: Exoc3l2 (exocyst complex component 3-like 2) Mus musculus
Analyze
Symbol: Exoc3l2
Name: exocyst complex component 3-like 2
RGD ID: 1621478
MGI Page MGI
Description: Predicted to enable SNARE binding activity. Acts upstream of or within in utero embryonic development. Predicted to be part of exocyst. Is expressed in rete testis and tunica albuginea of testis. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4933417E01Rik; AU042655; exocyst complex component 3-like protein 2; Gm19857; predicted gene, 19857
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,197,212 - 19,230,687 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,197,256 - 19,230,687 (+)EnsemblGRCm39 Ensembl
GRCm38719,463,287 - 19,496,762 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,463,331 - 19,496,762 (+)EnsemblGRCm38mm10GRCm38
MGSCv37720,063,253 - 20,082,111 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,647,578 - 18,655,282 (+)NCBIMGSCv36mm8
Celera716,875,415 - 16,902,567 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
exocyst  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14581517   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18287559  
PMID:21566143   PMID:21677750   PMID:21873635   PMID:27626380   PMID:27768725   PMID:27996060   PMID:28185240   PMID:29539633   PMID:30086153   PMID:30973865   PMID:38355793  


Genomics

Comparative Map Data
Exoc3l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,197,212 - 19,230,687 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,197,256 - 19,230,687 (+)EnsemblGRCm39 Ensembl
GRCm38719,463,287 - 19,496,762 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,463,331 - 19,496,762 (+)EnsemblGRCm38mm10GRCm38
MGSCv37720,063,253 - 20,082,111 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,647,578 - 18,655,282 (+)NCBIMGSCv36mm8
Celera716,875,415 - 16,902,567 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.92NCBI
EXOC3L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,212,370 - 45,245,407 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,212,370 - 45,245,407 (-)EnsemblGRCh38hg38GRCh38
GRCh371945,715,628 - 45,748,665 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,407,719 - 50,429,309 (-)NCBINCBI36Build 36hg18NCBI36
Celera1942,521,452 - 42,543,042 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,147,898 - 42,169,431 (-)NCBIHuRef
CHM1_11945,719,170 - 45,740,768 (-)NCBICHM1_1
T2T-CHM13v2.01948,039,015 - 48,072,079 (-)NCBIT2T-CHM13v2.0
Exoc3l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,241,784 - 88,273,352 (+)NCBIGRCr8
mRatBN7.2179,113,784 - 79,145,359 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,112,506 - 79,145,465 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0180,372,708 - 80,404,275 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,383,050 - 80,404,290 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,638,786 - 81,670,432 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera173,573,529 - 73,605,038 (+)NCBICelera
Cytogenetic Map1q21NCBI
Exoc3l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555552,261,241 - 2,277,340 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555552,260,885 - 2,281,784 (-)NCBIChiLan1.0ChiLan1.0
EXOC3L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,372,481 - 51,403,276 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,235,946 - 53,274,660 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,161,728 - 42,195,014 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,766,031 - 50,783,387 (-)NCBIpanpan1.1PanPan1.1panPan2
EXOC3L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,265,054 - 110,277,895 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,265,043 - 110,277,519 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,738,722 - 109,759,777 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,787,066 - 110,808,185 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,787,048 - 110,807,809 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,462,673 - 110,483,748 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,097,070 - 110,118,125 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,966,439 - 110,987,538 (+)NCBIUU_Cfam_GSD_1.0
LOC101970976
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,391,924 - 17,405,080 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367061,739,267 - 1,752,418 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC3L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,638,065 - 51,668,469 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,638,058 - 51,661,716 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EXOC3L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,670,789 - 38,706,058 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607318,266,461 - 18,299,547 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exoc3l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249072,159,935 - 2,179,736 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249072,158,565 - 2,172,103 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1275
Count of miRNA genes:411
Interacting mature miRNAs:489
Transcripts:ENSMUST00000011407, ENSMUST00000137613
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse

Markers in Region
RH129012  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38719,495,376 - 19,495,563UniSTSGRCm38
MGSCv37720,080,725 - 20,080,912UniSTSGRCm37
Celera716,901,181 - 16,901,368UniSTS
Cytogenetic Map7A3UniSTS
AU042655  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38719,496,608 - 19,496,736UniSTSGRCm38
MGSCv37720,081,957 - 20,082,085UniSTSGRCm37
Celera716,902,413 - 16,902,541UniSTS
Cytogenetic Map7A3UniSTS
Whitehead/MRC_RH7260.64UniSTS
UniSTS:235611  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38719,496,341 - 19,496,575UniSTSGRCm38
MGSCv37720,081,690 - 20,081,924UniSTSGRCm37
Celera716,902,146 - 16,902,380UniSTS
Cytogenetic Map7A3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000011407   ⟹   ENSMUSP00000011407
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl719,222,981 - 19,230,685 (+)Ensembl
GRCm38.p6 Ensembl719,489,056 - 19,496,760 (+)Ensembl
Ensembl Acc Id: ENSMUST00000137613   ⟹   ENSMUSP00000123025
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl719,197,256 - 19,230,687 (+)Ensembl
GRCm38.p6 Ensembl719,463,331 - 19,496,762 (+)Ensembl
RefSeq Acc Id: NM_001370800   ⟹   NP_001357729
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,197,212 - 19,230,687 (+)NCBI
GRCm38719,463,287 - 19,496,762 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001357729 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB30458 (Get FASTA)   NCBI Sequence Viewer  
  EDL23148 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000123025
  ENSMUSP00000123025.3
RefSeq Acc Id: NP_001357729   ⟸   NM_001370800
- UniProtKB: D3YUP5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000011407   ⟸   ENSMUST00000011407
Ensembl Acc Id: ENSMUSP00000123025   ⟸   ENSMUST00000137613

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3YUP5-F1-model_v2 AlphaFold D3YUP5 1-789 view protein structure

Promoters
RGD ID:6892092
Promoter ID:EPDNEW_M9497
Type:single initiation site
Name:Exoc3l2_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38719,489,584 - 19,489,644EPDNEW
RGD ID:6841060
Promoter ID:MM_KWN:49074
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:AK016842_EXOC3L2,   ENSMUST00000011407,   OTTMUST00000084941,   UC009FLZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36720,074,401 - 20,075,102 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921713 AgrOrtholog
Ensembl Genes ENSMUSG00000011263 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000137613 ENTREZGENE
  ENSMUST00000137613.9 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.70 UniProtKB/TrEMBL
InterPro EXOC3/Sec6_C UniProtKB/TrEMBL
  Sec6 UniProtKB/TrEMBL
MGD MGI:1921713 ENTREZGENE
NCBI Gene 74463 ENTREZGENE
PANTHER EXOCYST COMPLEX COMPONENT 3-LIKE 2 UniProtKB/TrEMBL
  Sec6 UniProtKB/TrEMBL
Pfam Sec6 UniProtKB/TrEMBL
PhenoGen Exoc3l2 PhenoGen
UniProt D3YUP5 ENTREZGENE, UniProtKB/TrEMBL
  Q9D431_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-11-22 Exoc3l2  exocyst complex component 3-like 2  Gm19857  predicted gene, 19857  Data merged from RGD:5139470 737654 PROVISIONAL