Mir194-1 (microRNA 194-1) - Rat Genome Database

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Gene: Mir194-1 (microRNA 194-1) Mus musculus
Analyze
Symbol: Mir194-1
Name: microRNA 194-1
RGD ID: 1608302
MGI Page MGI
Description: Acts upstream of or within cellular response to amino acid stimulus and cellular response to lipopolysaccharide. Part of RISC complex. Is expressed in several structures, including cranial ganglion; eye; gonad; hemolymphoid system gland; and inner ear. Orthologous to human MIR194-1 (microRNA 194-1).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: miR-194; mir-194-1; Mirn; Mirn19; Mirn194; Mirn194-1
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,045,516 - 185,045,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1185,045,516 - 185,045,582 (+)EnsemblGRCm39 Ensembl
GRCm381185,313,319 - 185,313,385 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1185,313,319 - 185,313,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,137,198 - 187,137,264 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Cytogenetic Map1H5NCBI
cM Map189.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir194-1Mousegastrointestinal stromal tumor  ISOMIR194-1 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Mir194-1MouseLoeys-Dietz syndrome 4  ISOMIR194-1 (Homo sapiens)8554872ClinVar Annotator: match by term: Loeys-Dietz syndrome 4ClinVarPMID:22772368 and PMID:28544325
Mir194-1MouseMartsolf Syndrome  ISOMIR194-1 (Homo sapiens)8554872ClinVar Annotator: match by term: Martsolf syndromeClinVarPMID:23420520 and PMID:28492532
Mir194-1Mouseparathyroid carcinoma  ISOMIR194-1 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
Mir194-1MouseUsher syndrome  ISOMIR194-1 (Homo sapiens)8554872ClinVar Annotator: match by term: Usher syndromeClinVarPMID:28041643
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir194-1MouseChemical and Drug Induced Liver Injury  ISOMIR194-1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28844483

1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir194-1Mouse1,3,5-trinitro-1,3,5-triazinane increases expressionEXP 6480464cyclonite results in increased expression of MIR194-1 mRNACTDPMID:19270793
Mir194-1Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of MIR194-1 mRNACTDPMID:37854252
Mir194-1Mousebis(2-ethylhexyl) phthalate decreases expressionEXP 6480464Diethylhexyl Phthalate results in decreased expression of MIR194CTDPMID:32642447
Mir194-1Mousebisphenol A increases methylationISOMir194-1 (Rattus norvegicus)6480464bisphenol A results in increased methylation of MIR194-1 geneCTDPMID:28505145
Mir194-1Mousechromium(6+) multiple interactionsISOMIR194-1 (Homo sapiens)6480464[zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of MIR194-1 mRNACTDPMID:35101437
Mir194-1MouseDiosbulbin B increases expressionEXP 6480464diosbulbin B results in increased expression of MIR194-1 mRNACTDPMID:28844483
Mir194-1Mouselead diacetate decreases expressionEXP 6480464lead acetate results in decreased expression of MIR194-1 mRNACTDPMID:36183778
Mir194-1Mousemethanol decreases expressionEXP 6480464Methanol results in decreased expression of MIR194CTDPMID:36780935
Mir194-1Mouseparacetamol increases expressionISOMir194-1 (Rattus norvegicus)6480464Acetaminophen results in increased expression of MIR194-1 mRNACTDPMID:27397436
Mir194-1Mousepyrethrins increases expressionEXP 6480464Pyrethrins results in increased expression of MIR194CTDPMID:35276145
Mir194-1Mousesodium arsenite increases expressionISOMir194-1 (Rattus norvegicus)6480464sodium arsenite results in increased expression of MIR194-1 mRNACTDPMID:25625412
Mir194-1Mousesodium arsenite decreases expressionISOMIR194-1 (Homo sapiens)6480464sodium arsenite results in decreased expression of MIR194-1 mRNACTDPMID:34032870
Mir194-1Mousestreptozocin increases expressionEXP 6480464Streptozocin results in increased expression of MIR194-1 mRNACTDPMID:27629361
Mir194-1Mousetetrachloromethane increases expressionISOMir194-1 (Rattus norvegicus)6480464Carbon Tetrachloride results in increased expression of MIR194-1 mRNACTDPMID:27397436
Mir194-1Mousetoosendanin increases expressionEXP 6480464toosendanin results in increased expression of MIR194-1 mRNACTDPMID:28844483

1 to 15 of 15 rows

Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir194-1Mouseextracellular space located_inISOMIR194-1 (Homo sapiens)9068941 PMID:25203061BHF-UCLPMID:25203061
Mir194-1MouseRISC complex part_ofIDA 2290270 PMID:23185045MGIPMID:23185045

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir194-1MousemRNA base-pairing post-transcriptional repressor activity enablesISOMIR194-1 (Homo sapiens)9068941 PMID:26147452ARUK-UCLPMID:26147452


#
Reference Title
Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12554859   PMID:14573789   PMID:16369549   PMID:16381832   PMID:17369397   PMID:17597072   PMID:17604727   PMID:17726050   PMID:18452032   PMID:18762567   PMID:19559694   PMID:20215419  
PMID:20413612   PMID:20467336   PMID:20548288   PMID:20979124   PMID:21037258   PMID:21267068   PMID:21887698   PMID:23185045   PMID:24197061   PMID:24205035   PMID:25285168   PMID:25412310  
PMID:25797619   PMID:27981676   PMID:28092415   PMID:28465351   PMID:28941704   PMID:28951211   PMID:30170731   PMID:30201567   PMID:31144266   PMID:31496625   PMID:31930767   PMID:32349546  
PMID:32522221   PMID:32661617   PMID:33068587   PMID:33479193   PMID:33662431   PMID:33839577   PMID:34843716   PMID:36200131   PMID:36868469   PMID:37224018   PMID:39218968  



Mir194-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,045,516 - 185,045,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1185,045,516 - 185,045,582 (+)EnsemblGRCm39 Ensembl
GRCm381185,313,319 - 185,313,385 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1185,313,319 - 185,313,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,137,198 - 187,137,264 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Cytogenetic Map1H5NCBI
cM Map189.49NCBI
MIR194-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381220,118,157 - 220,118,241 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1220,118,157 - 220,118,241 (-)EnsemblGRCh38hg38GRCh38
GRCh371220,291,499 - 220,291,583 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,358,121 - 218,358,205 (-)NCBINCBI36Build 36hg18NCBI36
Celera1193,510,708 - 193,510,792 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1190,965,852 - 190,965,936 (-)NCBIHuRef
CHM1_11221,563,984 - 221,564,068 (-)NCBICHM1_1
T2T-CHM13v2.01219,357,431 - 219,357,515 (-)NCBIT2T-CHM13v2.0
Mir194-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81399,382,716 - 99,382,798 (+)NCBIGRCr8
mRatBN7.21396,851,166 - 96,851,248 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,851,166 - 96,851,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1399,350,308 - 99,350,390 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013100,756,265 - 100,756,347 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01397,932,562 - 97,932,644 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013103,250,576 - 103,250,658 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13103,250,576 - 103,250,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,924,394 - 107,924,476 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1396,366,365 - 96,366,447 (+)NCBICelera
Cytogenetic Map13q26NCBI
MIR194
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13814,895,401 - 14,895,458 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3814,895,401 - 14,895,458 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3814,938,022 - 14,938,079 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03814,930,881 - 14,930,938 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3814,930,881 - 14,930,938 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03815,286,924 - 15,286,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03815,575,390 - 15,575,447 (-)NCBIUU_Cfam_GSD_1.0
MIR194B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl109,704,910 - 9,704,987 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1109,704,910 - 9,704,987 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,786,871 - 11,786,948 (-)NCBISscrofa10.2Sscrofa10.2susScr3

.

.
Variants in Mir194-1
12 total Variants

Predicted Targets
Summary Value
Count of predictions:10594
Count of gene targets:5479
Count of transcripts:8529
Interacting mature miRNAs:mmu-miR-194-1-3p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 79 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157456299191456436Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155526796189526897Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1167954584195154279Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152132744186132744Mouse
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172303451195154279Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160097157194097157Mouse
4142389Scfr1_mstem cell frequency regulator 1 (mouse)Not determined171632048189303617Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164143227190534272Mouse

1 to 10 of 79 rows






Ensembl Acc Id: ENSMUST00000083647
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1185,045,516 - 185,045,582 (+)Ensembl
GRCm38.p6 Ensembl1185,313,319 - 185,313,385 (+)Ensembl
RefSeq Acc Id: NR_029580
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391185,045,516 - 185,045,582 (+)NCBI
GRCm381185,313,319 - 185,313,385 (+)ENTREZGENE
MGSCv371187,137,198 - 187,137,264 (+)RGD
cM Map1 ENTREZGENE
Sequence:


1 to 9 of 9 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000065581 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083647 ENTREZGENE
MGD MGI:2676858 ENTREZGENE
miRBase MI0000236 ENTREZGENE
NCBI Gene 387189 ENTREZGENE
PhenoGen Mir194-1 PhenoGen
RNAcentral URS000029C2DC RNACentral
  URS00005B625D RNACentral
  URS000075EC31 RNACentral
1 to 9 of 9 rows