Dnase1l2 (deoxyribonuclease 1 like 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Dnase1l2 (deoxyribonuclease 1 like 2) Rattus norvegicus
Analyze
Symbol: Dnase1l2
Name: deoxyribonuclease 1 like 2
RGD ID: 1583566
Description: Predicted to enable DNA binding activity and deoxyribonuclease I activity. Predicted to be involved in DNA catabolic process. Predicted to act upstream of or within corneocyte development and hair follicle development. Predicted to be active in nucleus. Orthologous to human DNASE1L2 (deoxyribonuclease 1 like 2); INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; bromobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: deoxyribonuclease 1-like 2; deoxyribonuclease I-like 2; deoxyribonuclease-1-like 2; LOC681124; rCG35247-like; similar to Deoxyribonuclease I-like 2 precursor (DNase I-like 2)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,976,012 - 13,978,574 (-)NCBIGRCr8
mRatBN7.21013,471,850 - 13,473,447 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,471,479 - 13,473,763 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01013,812,335 - 13,814,514 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,812,707 - 13,814,304 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,629,321 - 13,631,498 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,698,596 - 13,701,079 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1013,151,976 - 13,154,155 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l2Ratautosomal dominant polycystic kidney disease  ISODNASE1L2 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal dominant polycystic kidney diseaseClinVarPMID:25741868
Dnase1l2Ratdevelopmental and epileptic encephalopathy 1  ISODNASE1L2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 1ClinVarPMID:28492532 and PMID:30866059
Dnase1l2Ratendometrial carcinoma  ISODNASE1L2 (Homo sapiens)8554872ClinVar Annotator: match by term: Endometrial carcinomaClinVar 
Dnase1l2Ratepilepsy  ISODNASE1L2 (Homo sapiens)8554872ClinVar Annotator: match by term: EpilepsyClinVarPMID:28492532
Dnase1l2RatIdiopathic Generalized Epilepsy  ISODNASE1L2 (Homo sapiens)8554872ClinVar Annotator: match by term: Idiopathic generalized epilepsyClinVarPMID:28492532
Dnase1l2Ratshort-rib thoracic dysplasia 9 with or without polydactyly  ISODNASE1L2 (Homo sapiens)8554872ClinVar Annotator: match by term: Saldino-Mainzer syndromeClinVarPMID:28492532
Dnase1l2Rattuberous sclerosis 2  ISODNASE1L2 (Homo sapiens)8554872ClinVar Annotator: match by term: Tuberous sclerosis 2ClinVarPMID:11112665 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l2RatProstatic Neoplasms  ISODNASE1L2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17013881

1 to 20 of 43 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l2Rat1-naphthyl isothiocyanate decreases expressionEXP 64804641-Naphthylisothiocyanate results in decreased expression of DNASE1L2 mRNACTDPMID:30723492
Dnase1l2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODnase1l2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DNASE1L2 mRNACTDPMID:21570461
Dnase1l2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISODNASE1L2 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of DNASE1L2 mRNACTDPMID:23152189
Dnase1l2Rat2-hydroxypropanoic acid decreases expressionISODNASE1L2 (Homo sapiens)6480464Lactic Acid results in decreased expression of DNASE1L2 mRNACTDPMID:30851411
Dnase1l2Rat3,4-methylenedioxymethamphetamine decreases expressionISODnase1l2 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of DNASE1L2 mRNACTDPMID:20188158
Dnase1l2Rat4,4'-sulfonyldiphenol decreases methylationISODNASE1L2 (Homo sapiens)6480464bisphenol S results in decreased methylation of DNASE1L2 geneCTDPMID:31601247
Dnase1l2Rat4-hydroxyphenyl retinamide increases expressionISODnase1l2 (Mus musculus)6480464Fenretinide results in increased expression of DNASE1L2 mRNACTDPMID:28973697
Dnase1l2Rataflatoxin B1 increases expressionISODnase1l2 (Mus musculus)6480464Aflatoxin B1 results in increased expression of DNASE1L2 mRNACTDPMID:19770486
Dnase1l2Rataristolochic acid A increases expressionISODNASE1L2 (Homo sapiens)6480464aristolochic acid I results in increased expression of DNASE1L2 mRNACTDPMID:33212167
Dnase1l2RatAroclor 1254 increases expressionISODnase1l2 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in increased expression of DNASE1L2 mRNACTDPMID:23650126
Dnase1l2Ratarsane multiple interactionsISODNASE1L2 (Homo sapiens)6480464[sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of DNASE1L2 mRNACTDPMID:32525701
Dnase1l2Ratarsenic atom multiple interactionsISODNASE1L2 (Homo sapiens)6480464[sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of DNASE1L2 mRNACTDPMID:32525701
Dnase1l2Ratarsenite(3-) increases methylationISODNASE1L2 (Homo sapiens)6480464arsenite results in increased methylation of DNASE1L2 promoterCTDPMID:23974009
Dnase1l2Ratbenzo[a]pyrene increases methylationISODNASE1L2 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of DNASE1L2 exon and Benzo(a)pyrene results in increased methylation of DNASE1L2 promoterCTDPMID:27901495
Dnase1l2Ratbenzo[b]fluoranthene increases expressionISODnase1l2 (Mus musculus)6480464benzo(b)fluoranthene results in increased expression of DNASE1L2 mRNACTDPMID:26377693
Dnase1l2RatBenzo[k]fluoranthene decreases expressionISODnase1l2 (Mus musculus)6480464benzo(k)fluoranthene results in decreased expression of DNASE1L2 mRNACTDPMID:26377693
Dnase1l2Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of DNASE1L2 mRNACTDPMID:25181051
Dnase1l2Ratbisphenol A decreases expressionISODnase1l2 (Mus musculus)6480464bisphenol A results in decreased expression of DNASE1L2 mRNACTDPMID:32156529 and PMID:35598803
Dnase1l2Ratbisphenol F decreases expressionISODnase1l2 (Mus musculus)6480464bisphenol F results in decreased expression of DNASE1L2 mRNACTDPMID:38685157
Dnase1l2Ratbromobenzene increases expressionEXP 6480464bromobenzene results in increased expression of DNASE1L2 mRNACTDPMID:32479839

1 to 20 of 43 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l2Ratcorneocyte development acts_upstream_of_or_withinISODnase1l2 (Mus musculus)1624291MGI:5308556 PMID:21307874RGDPMID:21307874
Dnase1l2RatDNA catabolic process involved_inIBAMGI:103157 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnase1l2RatDNA catabolic process involved_inIEAInterPro:IPR0162021600115GO_REF:0000002InterProGO_REF:0000002
Dnase1l2RatDNA catabolic process acts_upstream_of_or_withinISODnase1l2 (Mus musculus)1624291MGI:5308556 PMID:21307874RGDPMID:21307874
Dnase1l2RatDNA metabolic process involved_inIEAARBA:ARBA000288391600115GO_REF:0000117UniProtGO_REF:0000117
Dnase1l2Rathair follicle development acts_upstream_of_or_withinISODnase1l2 (Mus musculus)1624291MGI:5308556 PMID:21307874RGDPMID:21307874

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l2Ratnucleus is_active_inIBAMGI:1314633 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l2Ratcatalytic activity enablesIEAInterPro:IPR0051351600115GO_REF:0000002InterProGO_REF:0000002
Dnase1l2Ratdeoxyribonuclease I activity enablesIBAMGI:103157 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnase1l2RatDNA binding enablesIBAPANTHER:PTN000889801 and Dnase1l3 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnase1l2RatDNA nuclease activity enablesIEAInterPro:IPR0162021600115GO_REF:0000002InterProGO_REF:0000002
Dnase1l2Ratendonuclease activity enablesIEAUniProtKB-KW:KW-02551600115GO_REF:0000043UniProtGO_REF:0000043
Dnase1l2Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Dnase1l2Ratnuclease activity enablesIEAARBA:ARBA000291901600115GO_REF:0000117UniProtGO_REF:0000117
Dnase1l2Ratnuclease activity enablesIEAUniProtKB-KW:KW-05401600115GO_REF:0000043UniProtGO_REF:0000043
Dnase1l2Ratprotein binding enablesISODNASE1L2 (Homo sapiens)1624291UniProtKB:P11021 more ...RGDPMID:28514442 and PMID:33961781
1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:21307874  



Dnase1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,976,012 - 13,978,574 (-)NCBIGRCr8
mRatBN7.21013,471,850 - 13,473,447 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,471,479 - 13,473,763 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01013,812,335 - 13,814,514 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,812,707 - 13,814,304 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,629,321 - 13,631,498 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,698,596 - 13,701,079 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1013,151,976 - 13,154,155 (-)NCBICelera
Cytogenetic Map10q12NCBI
DNASE1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,236,444 - 2,238,711 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,235,816 - 2,238,711 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,286,445 - 2,288,712 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,226,469 - 2,228,713 (+)NCBINCBI36Build 36hg18NCBI36
Build 34162,226,468 - 2,228,712NCBI
Celera162,500,889 - 2,503,133 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,212,560 - 2,214,798 (+)NCBIHuRef
CHM1_1162,286,417 - 2,288,661 (+)NCBICHM1_1
T2T-CHM13v2.0162,258,893 - 2,261,160 (+)NCBIT2T-CHM13v2.0
Dnase1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,659,054 - 24,662,075 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,659,055 - 24,662,079 (-)EnsemblGRCm39 Ensembl
GRCm381724,440,087 - 24,443,763 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,440,081 - 24,443,105 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,577,713 - 24,580,046 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,168,165 - 24,170,684 (-)NCBIMGSCv36mm8
Celera1724,955,439 - 24,957,592 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.39NCBI
Dnase1l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,028,168 - 15,031,110 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,028,168 - 15,031,110 (-)NCBIChiLan1.0ChiLan1.0
DNASE1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,737,754 - 2,740,608 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,518,655 - 6,522,535 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,093,669 - 1,096,123 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,336,203 - 2,338,684 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,336,768 - 2,338,391 (+)Ensemblpanpan1.1panPan2
DNASE1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha639,979,265 - 39,982,569 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,048,460 - 39,051,772 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,048,500 - 39,052,042 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,733,481 - 38,736,785 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,705,790 - 38,709,109 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,184,517 - 39,187,829 (-)NCBIUU_Cfam_GSD_1.0
Dnase1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,898,483 - 104,901,279 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,808,463 - 1,810,019 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,808,184 - 1,810,735 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNASE1L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,757,296 - 39,761,080 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,757,725 - 39,761,497 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,418,925 - 42,423,186 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNASE1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,130,879 - 2,133,817 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,131,854 - 2,133,524 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,925,769 - 28,928,101 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnase1l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462482449,949 - 53,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462482449,877 - 53,383 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Dnase1l2
3 total Variants

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:48
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000012203
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat

1 to 10 of 25 rows
BF401693  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,471,743 - 13,471,834 (+)MAPPERmRatBN7.2
Rnor_6.01013,812,601 - 13,812,691NCBIRnor6.0
Rnor_5.01013,629,587 - 13,629,677UniSTSRnor5.0
RGSC_v3.41013,698,862 - 13,698,952UniSTSRGSC3.4
Celera1013,152,242 - 13,152,332UniSTS
RH 3.4 Map10190.7UniSTS
Cytogenetic Map10q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000012203   ⟹   ENSRNOP00000012203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,471,479 - 13,473,763 (-)Ensembl
Rnor_6.0 Ensembl1013,812,707 - 13,814,304 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118986   ⟹   ENSRNOP00000081688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,471,479 - 13,473,763 (-)Ensembl
RefSeq Acc Id: NM_001427102   ⟹   NP_001414031
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,976,012 - 13,978,297 (-)NCBI
RefSeq Acc Id: XM_063269828   ⟹   XP_063125898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,976,012 - 13,978,574 (-)NCBI
RefSeq Acc Id: XM_063269829   ⟹   XP_063125899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,976,012 - 13,978,574 (-)NCBI
RefSeq Acc Id: XM_063269830   ⟹   XP_063125900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,976,012 - 13,978,574 (-)NCBI
RefSeq Acc Id: XM_063269831   ⟹   XP_063125901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,976,012 - 13,978,574 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001414031 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125898 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125899 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125900 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125901 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03827 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012203
  ENSRNOP00000012203.3
  ENSRNOP00000081688
  ENSRNOP00000081688.1
1 to 10 of 10 rows
Ensembl Acc Id: ENSRNOP00000012203   ⟸   ENSRNOT00000012203
Ensembl Acc Id: ENSRNOP00000081688   ⟸   ENSRNOT00000118986
RefSeq Acc Id: XP_063125901   ⟸   XM_063269831
- Peptide Label: isoform X4
- UniProtKB: A6HCS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125900   ⟸   XM_063269830
- Peptide Label: isoform X3
- UniProtKB: A6HCS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125899   ⟸   XM_063269829
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZT23 (UniProtKB/TrEMBL),   A6HCS1 (UniProtKB/TrEMBL)
Endonuclease/exonuclease/phosphatase

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZF29-F1-model_v2 AlphaFold D3ZF29 1-278 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-25858 BioCyc
Ensembl Genes ENSRNOG00000042352 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012203 ENTREZGENE
  ENSRNOT00000012203.6 UniProtKB/TrEMBL
  ENSRNOT00000118986 ENTREZGENE
  ENSRNOT00000118986.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.10.10 UniProtKB/TrEMBL
InterPro Deoxyribonuclease-1_AS UniProtKB/TrEMBL
  DNase_I-like UniProtKB/TrEMBL
  DNASE_I_2 UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/TrEMBL
  Endo/exonuclease/phosphatase UniProtKB/TrEMBL
NCBI Gene 681124 ENTREZGENE
PANTHER DEOXYRIBONUCLEASE UniProtKB/TrEMBL
  DEOXYRIBONUCLEASE-1-LIKE 2 UniProtKB/TrEMBL
Pfam Exo_endo_phos UniProtKB/TrEMBL
PhenoGen Dnase1l2 PhenoGen
PIRSF DNase_I_euk UniProtKB/TrEMBL
PRINTS DNASEI UniProtKB/TrEMBL
PROSITE DNASE_I_1 UniProtKB/TrEMBL
  DNASE_I_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042352 RatGTEx
SMART DNaseIc UniProtKB/TrEMBL
Superfamily-SCOP Exo_endo_phos UniProtKB/TrEMBL
UniProt A0A8I5ZT23 ENTREZGENE, UniProtKB/TrEMBL
  A6HCS1 ENTREZGENE, UniProtKB/TrEMBL
  A6HCS2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZF29 ENTREZGENE, UniProtKB/TrEMBL
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Dnase1l2  deoxyribonuclease 1 like 2  Dnase1l2  deoxyribonuclease I-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Dnase1l2  deoxyribonuclease I-like 2  LOC100364462  rCG35247-like  Data merged from RGD:2320998 1643240 APPROVED
2012-01-24 Dnase1l2  deoxyribonuclease I-like 2  Dnase1l2  deoxyribonuclease 1-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100364462  rCG35247-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-05 Dnase1l2  deoxyribonuclease 1-like 2  LOC681124  similar to Deoxyribonuclease I-like 2 precursor (DNase I-like 2)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC681124  similar to Deoxyribonuclease I-like 2 precursor (DNase I-like 2)      Symbol and Name status set to provisional 70820 PROVISIONAL