Inpp5k (inositol polyphosphate 5-phosphatase K) - Rat Genome Database

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Gene: Inpp5k (inositol polyphosphate 5-phosphatase K) Mus musculus
Analyze
Symbol: Inpp5k
Name: inositol polyphosphate 5-phosphatase K
RGD ID: 1558265
MGI Page MGI
Description: Enables inositol bisphosphate phosphatase activity; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; and vasopressin receptor activity. Involved in several processes, including cellular response to cAMP; negative regulation of macromolecule metabolic process; and negative regulation of signal transduction. Acts upstream of or within in utero embryonic development and response to insulin. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital muscular dystrophy with cataracts and intellectual disability. Orthologous to human INPP5K (inositol polyphosphate-5-phosphatase K).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C62; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; phosphatidylinositol-4,5-bisphosphate 5-phosphatase; PI-5-phosphatase related; Pps; putative PI-5-phosphatase; skeletal muscle and kidney enriched inositol polyphosphate phosphatase; skeletal muscle and kidney-enriched inositol phosphatase; SKIP
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,519,893 - 75,539,691 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,521,814 - 75,539,697 (+)EnsemblGRCm39 Ensembl
GRCm381175,629,067 - 75,648,865 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,630,988 - 75,648,871 (+)EnsemblGRCm38mm10GRCm38
MGSCv371175,444,522 - 75,462,367 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,447,215 - 75,465,060 (+)NCBIMGSCv36mm8
Celera1183,140,156 - 83,157,894 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to cAMP  (IDA)
cellular response to epidermal growth factor stimulus  (ISO,ISS)
cellular response to hormone stimulus  (IDA)
cellular response to insulin stimulus  (ISO,ISS)
cellular response to tumor necrosis factor  (ISO,ISS)
dephosphorylation  (IDA,ISO)
G protein-coupled receptor signaling pathway  (IDA)
glucose homeostasis  (IMP)
in utero embryonic development  (IMP)
negative regulation by host of viral transcription  (ISO,ISS)
negative regulation of calcium ion transport  (ISO,ISS)
negative regulation of D-glucose transmembrane transport  (ISO,ISS)
negative regulation of dephosphorylation  (IMP)
negative regulation of DNA-templated transcription  (IDA)
negative regulation of glycogen (starch) synthase activity  (IMP)
negative regulation of glycogen biosynthetic process  (IBA,IMP,ISO)
negative regulation of insulin receptor signaling pathway  (IBA,IMP,ISO)
negative regulation of MAP kinase activity  (ISO,ISS)
negative regulation of peptidyl-serine phosphorylation  (IMP,ISO)
negative regulation of peptidyl-threonine phosphorylation  (ISO,ISS)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IBA,IMP,ISO)
negative regulation of protein kinase activity  (ISO,ISS)
negative regulation of protein phosphorylation  (IDA)
negative regulation of protein targeting to membrane  (ISO,ISS)
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate  (ISO,ISS)
negative regulation of stress fiber assembly  (ISO,ISS)
phosphatidylinositol dephosphorylation  (ISO,ISS)
positive regulation of DNA-templated transcription  (IDA)
positive regulation of renal water transport  (IDA)
positive regulation of urine volume  (IDA)
protein localization to plasma membrane  (IDA)
regulation of glycogen biosynthetic process  (IMP)
response to insulin  (IMP)
ruffle assembly  (ISO,ISS)

Cellular Component
cytoplasm  (IDA)
cytosol  (ISO,ISS)
endoplasmic reticulum  (IBA,IDA,ISO,ISS)
membrane  (ISO,ISS)
neuron projection  (IBA,ISO,ISS)
nucleus  (ISO,ISS)
perinuclear region of cytoplasm  (ISO,ISS)
plasma membrane  (IBA,ISO,ISS)
ruffle  (IBA,ISO,ISS)
ruffle membrane  (ISO,ISS)
trans-Golgi network  (ISO,ISS)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7237550   PMID:9182797   PMID:10325425   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11471062   PMID:12477932   PMID:12536145   PMID:14610273  
PMID:14681479   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18573875   PMID:18799693   PMID:19250614   PMID:21267068   PMID:21677750   PMID:21712384   PMID:21873635   PMID:21938401  
PMID:22247557   PMID:22751929   PMID:22815484   PMID:25446075   PMID:26376412   PMID:26483413   PMID:32554809   PMID:33119550   PMID:35135857   PMID:37000875   PMID:38355793   PMID:38559586  


Genomics

Comparative Map Data
Inpp5k
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,519,893 - 75,539,691 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,521,814 - 75,539,697 (+)EnsemblGRCm39 Ensembl
GRCm381175,629,067 - 75,648,865 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,630,988 - 75,648,871 (+)EnsemblGRCm38mm10GRCm38
MGSCv371175,444,522 - 75,462,367 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,447,215 - 75,465,060 (+)NCBIMGSCv36mm8
Celera1183,140,156 - 83,157,894 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
INPP5K
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38171,494,577 - 1,516,612 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl171,494,577 - 1,516,742 (-)EnsemblGRCh38hg38GRCh38
GRCh37171,397,871 - 1,419,906 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,344,621 - 1,366,704 (-)NCBINCBI36Build 36hg18NCBI36
Celera171,413,368 - 1,435,621 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef171,298,037 - 1,320,343 (-)NCBIHuRef
CHM1_1171,406,563 - 1,428,873 (-)NCBICHM1_1
T2T-CHM13v2.0171,383,334 - 1,405,368 (-)NCBIT2T-CHM13v2.0
Inpp5k
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,974,183 - 60,995,047 (+)NCBIGRCr8
mRatBN7.21060,474,262 - 60,495,813 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,475,897 - 60,496,773 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,122,645 - 65,142,529 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01064,628,064 - 64,647,946 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,090,639 - 60,110,523 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01063,775,639 - 63,796,879 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1063,776,378 - 63,795,899 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01064,209,340 - 64,228,728 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,953,425 - 62,971,016 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11062,967,047 - 62,984,638 (+)NCBI
Celera1059,503,324 - 59,523,140 (+)NCBICelera
Cytogenetic Map10q24NCBI
Inpp5k
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554811,651,902 - 1,673,893 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554811,651,422 - 1,674,402 (+)NCBIChiLan1.0ChiLan1.0
INPP5K
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,065,156 - 9,087,254 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,031,426 - 11,053,955 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0171,477,511 - 1,499,765 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1171,377,310 - 1,399,373 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,377,312 - 1,399,373 (-)Ensemblpanpan1.1panPan2
INPP5K
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,660,445 - 45,680,407 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,660,446 - 45,680,363 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha944,812,547 - 44,832,619 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0946,488,250 - 46,508,538 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl946,487,348 - 46,508,366 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1945,258,657 - 45,278,900 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0945,553,108 - 45,573,180 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0945,606,572 - 45,626,642 (-)NCBIUU_Cfam_GSD_1.0
Inpp5k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,763,537 - 44,785,099 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,641,127 - 7,661,787 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,641,485 - 7,662,033 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INPP5K
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,718,491 - 47,738,475 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,717,898 - 47,738,540 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21249,602,564 - 49,623,319 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INPP5K
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,171,059 - 1,192,241 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl161,170,899 - 1,191,965 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605920,795,694 - 20,817,596 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inpp5k
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247864,214,916 - 4,236,563 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247864,213,430 - 4,236,930 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Inpp5k
586 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2629
Count of miRNA genes:746
Interacting mature miRNAs:974
Transcripts:ENSMUST00000006286, ENSMUST00000129298, ENSMUST00000130318, ENSMUST00000136605, ENSMUST00000139856, ENSMUST00000149134, ENSMUST00000150857
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_388367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF483522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF483523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL591440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U96724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U96726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000006286   ⟹   ENSMUSP00000006286
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,521,814 - 75,539,697 (+)Ensembl
GRCm38.p6 Ensembl1175,630,988 - 75,648,871 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129298
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,521,863 - 75,526,094 (+)Ensembl
GRCm38.p6 Ensembl1175,631,037 - 75,635,268 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,529,963 - 75,538,102 (+)Ensembl
GRCm38.p6 Ensembl1175,639,137 - 75,647,276 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136605
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,521,855 - 75,539,689 (+)Ensembl
GRCm38.p6 Ensembl1175,631,029 - 75,648,863 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139856   ⟹   ENSMUSP00000121060
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,537,672 - 75,538,690 (+)Ensembl
GRCm38.p6 Ensembl1175,646,846 - 75,647,864 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,537,612 - 75,538,557 (+)Ensembl
GRCm38.p6 Ensembl1175,646,786 - 75,647,731 (+)Ensembl
Ensembl Acc Id: ENSMUST00000150857   ⟹   ENSMUSP00000119996
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,521,881 - 75,539,691 (+)Ensembl
GRCm38.p6 Ensembl1175,631,055 - 75,648,865 (+)Ensembl
RefSeq Acc Id: NM_008916   ⟹   NP_032942
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391175,521,846 - 75,539,691 (+)NCBI
GRCm381175,631,020 - 75,648,865 (+)NCBI
MGSCv371175,444,522 - 75,462,367 (+)RGD
Celera1183,140,156 - 83,157,894 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532507   ⟹   XP_006532570
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391175,519,893 - 75,539,691 (+)NCBI
GRCm381175,629,067 - 75,647,923 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004936848
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391175,519,893 - 75,539,691 (+)NCBI
Sequence:
RefSeq Acc Id: XR_388367
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391175,519,893 - 75,539,691 (+)NCBI
GRCm381175,629,067 - 75,648,865 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032942   ⟸   NM_008916
- UniProtKB: O09040 (UniProtKB/Swiss-Prot),   Q8C5L6 (UniProtKB/Swiss-Prot),   Q5ND43 (UniProtKB/TrEMBL),   Q05DI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006532570   ⟸   XM_006532507
- Peptide Label: isoform X1
- UniProtKB: Q05DI2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000119996   ⟸   ENSMUST00000150857
Ensembl Acc Id: ENSMUSP00000121060   ⟸   ENSMUST00000139856
Ensembl Acc Id: ENSMUSP00000006286   ⟸   ENSMUST00000006286
Protein Domains
Inositol polyphosphate-related phosphatase   SKICH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C5L6-F1-model_v2 AlphaFold Q8C5L6 1-468 view protein structure

Promoters
RGD ID:6821129
Promoter ID:MM_KWN:8524
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000006286,   OTTMUST00000014034,   UC007KEJ.1,   UC007KEL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361175,444,096 - 75,444,596 (+)MPROMDB
RGD ID:6821111
Promoter ID:MM_KWN:8526
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:OTTMUST00000014029,   OTTMUST00000014033
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361175,460,311 - 75,460,811 (+)MPROMDB
RGD ID:8675562
Promoter ID:EPDNEW_M15812
Type:initiation region
Name:Inpp5k_1
Description:Mus musculus inositol polyphosphate 5-phosphatase K , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381175,631,040 - 75,631,100EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1194899 AgrOrtholog
Ensembl Genes ENSMUSG00000006127 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000006286 ENTREZGENE
  ENSMUST00000006286.9 UniProtKB/Swiss-Prot
  ENSMUST00000139856.2 UniProtKB/TrEMBL
  ENSMUST00000150857.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2840 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.60.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Endo/exonu/phosph_ase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IP5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKICH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19062 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1194899 ENTREZGENE
NCBI Gene 19062 ENTREZGENE
PANTHER INOSITOL 5-PHOSPHATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Exo_endo_phos2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKICH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Inpp5k PhenoGen
SMART IPPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Exo_endo_phos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D6RI67_MOUSE UniProtKB/TrEMBL
  INP5K_MOUSE UniProtKB/Swiss-Prot
  O09040 ENTREZGENE
  Q05DI2 ENTREZGENE, UniProtKB/TrEMBL
  Q5ND43 ENTREZGENE, UniProtKB/TrEMBL
  Q5ND44_MOUSE UniProtKB/TrEMBL
  Q8C5L6 ENTREZGENE
UniProt Secondary O09040 UniProtKB/Swiss-Prot