INPP5K (inositol polyphosphate-5-phosphatase K)

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Gene: INPP5K (inositol polyphosphate-5-phosphatase K) Sus scrofa

Analyze

Symbol:

INPP5K

Name:

inositol polyphosphate-5-phosphatase K

RGD ID:

14016895

Description:

ENCODES a protein that exhibits inositol bisphosphate phosphatase activity (ortholog); inositol trisphosphate phosphatase activity (ortholog); phosphatidylinositol phosphate 5-phosphatase activity (ortholog); INVOLVED IN cellular response to cAMP (ortholog); cellular response to hormone stimulus (ortholog); dephosphorylation (ortholog); ASSOCIATED WITH congenital muscular dystrophy with cataracts and intellectual disability (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); membrane (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

inositol polyphosphate 5-phosphatase K; skeletal muscle- and kidney-enriched inositol phosphatase; SKIP

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	47,717,907 - 47,738,477 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	47,717,898 - 47,738,540 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	49,602,564 - 49,623,319 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital muscular dystrophy with cataracts and intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to cAMP (IEA,ISO)

cellular response to epidermal growth factor stimulus (IEA)

cellular response to hormone stimulus (ISO)

cellular response to insulin stimulus (IEA)

cellular response to tumor necrosis factor (IEA)

dephosphorylation (ISO)

G protein-coupled receptor signaling pathway (IEA,ISO)

glucose homeostasis (IEA,ISO)

in utero embryonic development (IEA,ISO)

inositol phosphate dephosphorylation (IBA)

negative regulation by host of viral transcription (IEA)

negative regulation of calcium ion transport (IEA)

negative regulation of dephosphorylation (IEA,ISO)

negative regulation of glucose transmembrane transport (IEA)

negative regulation of glycogen (starch) synthase activity (IEA,ISO)

negative regulation of glycogen biosynthetic process (IBA,ISO)

negative regulation of insulin receptor signaling pathway (IBA,ISO)

negative regulation of MAP kinase activity (IEA)

negative regulation of peptidyl-serine phosphorylation (IBA,ISO)

negative regulation of peptidyl-threonine phosphorylation (IEA)

negative regulation of protein kinase activity (ISO)

negative regulation of protein kinase B signaling (IBA,ISO)

negative regulation of protein phosphorylation (ISO)

negative regulation of protein targeting to membrane (IEA)

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate (IEA)

negative regulation of stress fiber assembly (IEA)

negative regulation of transcription, DNA-templated (IEA,ISO)

phosphatidylinositol dephosphorylation (IBA,IEA)

positive regulation of renal water transport (IEA,ISO)

positive regulation of transcription, DNA-templated (IEA,ISO)

positive regulation of urine volume (IEA,ISO)

protein localization to plasma membrane (IEA,ISO)

regulation of glycogen biosynthetic process (ISO)

response to insulin (ISO)

ruffle assembly (IEA)

Cellular Component

cytoplasm (IBA,ISO)

cytosol (IEA)

endoplasmic reticulum (IBA,ISO)

membrane (ISO)

neuron projection (IEA)

nucleus (IEA)

perinuclear region of cytoplasm (IEA)

plasma membrane (IBA,ISO)

ruffle (IBA)

ruffle membrane (IEA)

trans-Golgi network (IEA)

Molecular Function

inositol bisphosphate phosphatase activity (IBA,ISO)

inositol trisphosphate phosphatase activity (ISO)

inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity (IEA)

inositol-1,4,5-trisphosphate 5-phosphatase activity (IEA)

inositol-polyphosphate 5-phosphatase activity (IEA)

phosphatidylinositol phosphate 5-phosphatase activity (ISO)

phosphatidylinositol trisphosphate phosphatase activity (ISO)

phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity (IBA,ISO)

phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity (IBA)

protein binding (ISO)

vasopressin receptor activity (IEA,ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:20336382	PMID:22682687

Genomics

Comparative Map Data

INPP5K
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	47,717,907 - 47,738,477 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	47,717,898 - 47,738,540 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	49,602,564 - 49,623,319 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

INPP5K
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	17	1,494,577 - 1,516,742 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	17	1,494,575 - 1,516,735 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	17	1,397,869 - 1,420,182 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	17	1,397,871 - 1,419,906 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	1,344,621 - 1,366,704 (-)	NCBI	NCBI36		hg18	NCBI36
Celera	17	1,413,368 - 1,435,621 (-)	NCBI
Cytogenetic Map	17	p13.3	NCBI
HuRef	17	1,298,037 - 1,320,343 (-)	NCBI		HuRef
CHM1_1	17	1,406,563 - 1,428,873 (-)	NCBI		CHM1_1

Inpp5k
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	75,519,893 - 75,539,691 (+)	NCBI	GRCm39		mm39
GRCm38	11	75,629,067 - 75,648,865 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	75,630,988 - 75,648,871 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	75,444,522 - 75,462,367 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	75,447,215 - 75,465,060 (+)	NCBI			mm8
Celera	11	83,140,156 - 83,157,894 (+)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	45.92	NCBI

Inpp5k
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	60,474,262 - 60,495,813 (+)	NCBI
Rnor_6.0 Ensembl	10	63,776,378 - 63,795,899 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	10	63,775,639 - 63,796,879 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	10	64,209,340 - 64,228,728 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	62,953,425 - 62,971,016 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	10	62,967,047 - 62,984,638 (+)	NCBI
Celera	10	59,503,324 - 59,523,140 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Inpp5k
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	1,651,902 - 1,673,893 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	1,651,422 - 1,674,402 (+)	NCBI	ChiLan1.0	ChiLan1.0

INPP5K
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	17	1,377,310 - 1,399,373 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	1,377,312 - 1,399,373 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	17	1,477,511 - 1,499,765 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

INPP5K
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	45,660,446 - 45,680,363 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	45,660,445 - 45,680,407 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Inpp5k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936538	7,641,485 - 7,662,033 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

INPP5K
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	1,171,059 - 1,192,241 (-)	NCBI
ChlSab1.1 Ensembl	16	1,170,899 - 1,191,965 (-)	Ensembl

Inpp5k
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624786	4,213,430 - 4,236,930 (-)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium				1		1		1
Low	10	4	3	4	2	22	2	2	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001190292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005657013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013989998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021066068	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK234551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK346290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK395754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP312656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01102363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ504265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ504266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSSSCT00000030204 ⟹ ENSSSCP00000024039

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	12	47,717,907 - 47,738,475 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000030655 ⟹ ENSSSCP00000025324

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	12	47,717,990 - 47,738,400 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000075492 ⟹ ENSSSCP00000069238

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	12	47,717,990 - 47,736,551 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000091212 ⟹ ENSSSCP00000070231

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	12	47,717,929 - 47,738,477 (-)	Ensembl

RefSeq Acc Id:

NM_001190292 ⟹ NP_001177221

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	47,719,157 - 47,738,346 (-)	NCBI

Sequence:

show sequence

ACCGCGTGGGAACGATGGCTGCCACGAACCCCCAGACCGAACCGAGAAGCAGGACGCTCAGCAT
ACATGTCGCGACGTGGAACGTGGCCTCTGCAGCACCCCCTCCAGACCTCAGTGATCTGCTCCAG
CTGCACACCCCGAACCTGAATCTGGACGTGTATGTCATTGGTTTGCAGGAAATGAACTGTGGGA
TCATGAGCCTCCTTTCTGACACTGCCTTTGAAGACCCGTGGAGCAGTTTCTTCATGGATGTGCT
TTCCCCTCTGAGCTTCGTCAAGGTCTCCAGCGTCCGCATGCAGGGGCTCCTCTTACTGGTATTT
GCCAAGTACCAGCATTTGCCCTTTATCCAGATCCTCTCTGCTAAATCCACCCCCACTGGCCTCT
TCGGGTATTGGGGGAACAAAGGGGGCGTCAACATATTCCTGAAGCTCTACGGCTACTACGTCAG
CATCATCAACTGCCACCTGCCCCCACATATGGCCAATAATGACCAGCGGCTGGAGCATTTTGAC
CGGATCCTGGAGATGCAGAATTTTGAGGCACAGGATATCCCCAACATCCTGGACCACGACCTCA
TTCTCTGGTTTGGAGACATGAACTTTCGGATCGAGGACTTTGGGTTGCACTTTGTTCGGGAATC
CATAAAACATCAGTGCTACAGTGACCTGTGGGAGAAGGATCAGCTCAGCATTGCCAAGAGACAT
GACCCTCTGCTCCGGGAGTTCCAGGAGGGACCCCTGCTCTTCCCGCCCACCTACAAGTTCGATA
AGAACTCCAACAACTATGACACAAGTGAGAAAAAACGCAAGCCTGCGTGGACCGACCGCATCCT
TTGGAGGTTGAAGCGGCAGCCCCAGGCCGACTGCCACCCCCCCACACTGCCAGCGCCCCACTTC
TCCCTGGTTCTGAGGAGCTACGTCAGCCACATGATGTACAGCATCAGTGACCACAAGCCTGTCA
CCGGCACCTTTGACTTGGAGCTGAAGCCGCTGGTATCTGCTCCGCTGATCACCCTGCTCCCCGA
GGGCCCGTGTACCACCGAGAGCGACCTGCTCATCAGCTACTCCCTGGCCTCGGACTTCCTCAGC
AGCCCCTGGGACTGGATCGGACTGTACAAGGTGGGGCTGCGCCACATTAATGACTATGTGTCAT
ATGTCTGGGTCGGGGACAACCAGGTCTCCTTCGGCGACCAGCTGAACCAGGTATACATCAGCCT
CAGCGACATCCCTGAGACTGAGGATGGGTTTCTCCTCTTTTACTATAGCAACAGCCTGCGTTCT
GTGGTGGGGATAAGCAGACCCTTCAAGATCCAGCCTCGCTCCTTCCTGGAGCAGGACTCACTGG
ATGAAGCCCAACCACAGATCTGAGCCAGGATGCGAGTGAACCCGGGCGGAGGCCGGCGCTGGCT
GCCAGCTCTGCCTTCACTGCCAGGAGCACTGGGGGCCCAGCCCTGCCCCCTGAGGAGGCTGCAA
GTCTCCTCCACCTCCCAGGGCGAGTTCTAGCCACACTCCCTCCCTCTCCGCAGTCCAGATCTCC
AGGATCAGCCCCTTCAATACAGGTTTCTGTGGCTCAGGT

hide sequence

RefSeq Acc Id:

XM_005657013 ⟹ XP_005657070

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	47,717,898 - 47,738,532 (-)	NCBI

Sequence:

show sequence

TTCCCCCGGGCCGCGCCACCCAGAGCCTTCCGTGCGCCTAGGCCCCGCCTCTTACGGAAGCCGA
GGCGGAGGGTCGGAATCCGGAAGAAAAACAATCGAGCGAGTGAGCTGACCGGCACCTGCTACCC
GATCGGGACAGATCAAGCCAGGATCCGCTGAGGCTGGGAGACGCGAACCAGCCGGGGCACCGCG
TGGGAACGATGGCTGCCACGAACCCCCAGACCGAACCGAGAAGCAGGACGCTCAGCATACATGT
CGTGACGTGGAACGTGGCCTCTGCAGCACCCCCTCCAGACCTCAGTGATCTGCTCCAGCTGCAC
ACCCCGAACCTGAATCTGGACGTGTATGTCATTGGTTTGCAGGAAATGAACTGTGGGATCATGA
GCCTCCTTTCTGACACTGCCTTTGAAGACCCGTGGAGCAGTTTCTTCATGGATGTGCTTTCCCC
TCTGAGCTTCGTCAAGGTCTCCAGCGTCCGCATGCAGGGGCTCCTCTTACTGGTATTTGCCAAG
TACCAGCATTTGCCCTTTATCCAGATCCTCTCTGCTAAATCCACCCCCACTGGCCTCTTCGGGT
ATTGGGGGAACAAAGGGGGCGTCAACATATTCCTGAAGCTCTACGGCTACTACGTCAGCATCAT
CAACTGCCACCTGCCCCCACATATGGCCAATAATGACCAGCGGCTGGAGCATTTTGACCGGATC
CTGGAGATGCAGAATTTTGAGGCACAGGATATCCCCAACATCCTGGACCACGACCTCATTCTCT
GGTTTGGAGACATGAACTTTCGGATCGAGGACTTTGGGTTGCACTTTGTTCGGGAATCCATAAA
ACATCAGTGCTACAGTGACCTGTGGGAGAAGGATCAGCTCAGCATTGCCAAGAGACATGACCCT
CTGCTCCGGGAGTTCCAGGAGGGACCCCTGCTCTTCCCGCCCACCTACAAGTTCGATAAGAACT
CCAACAACTATGACACAAGTGAGAAAAAACGCAAGCCTGCGTGGACCGACCGCATCCTTTGGAG
GTTGAAGCGGCAGCCCCAGGCCGACTGCCACCCCCCCACACTGCCAGGGCCCCACTTCTCCCTG
GTTCTGAGGAGCTACGTCAGCCACATGATGTACAGCATCAGTGACCACAAGCCTGTCACCGGCA
CCTTTGACTTGGAGCTGAAGCCGCTGGTATCTGCTCCGCTGATCACCCTGCTCCCCGAGGGCCC
GTGTACCACCGAGAGCGACCTGCTCATCAGCTACTCCCTGGCCTCGGACTTCCTCAGCAGCCCC
TGGGACTGGATCGGACTGTACAAGGTGGGGCTGCGCCACATTAATGACTATGTGTCATATGTCT
GGGTCGGGGACAACCAGGTCTCCTTCGGCGACCAGCTGAACCAGCAACAGCCTGCGTTCTGTGG
TGGGGATAAGCAGACCCTTCAAGATCCAGCCTCGCTCCTTCCTGGAGCAGGACTCACTGGATGA
AGCCCAACCACAGATCTGAGCCAGGATGCGAGTGAACCCGGGCGGAGGCCGGCGCTGGCTGCCA
GCTCTGCCTTCACTGCCAGGAGCACTGGGGGCCCAGCCCTGCCCCCTGAGGAGGCTGCAAGTCT
CCTCCACCTCCCAGGGCGAGTTCTAGCCACACTCCCTCCCTCTCCGCAGTCCAGATCTCCAGGA
TCAGCCCCTTCAATACAGGTTTCTGTGGCTCAGGTGTGAGTGAAACCAGCTAGTTTGTCAGCAG
TGAAGCTCTAGACAGTCCGCTGGAGGAAGGACCCTCCAGCTTGCATCTCATTTCTCCATCTTCC
CCACACACACACTTGTAGTCCTGCCCAAGCAGGCCTGCCGGGCACATGCCCCATCTGGCACAGG
CCCGCATTCTTGTCACGCCACCCTGGGCCTTAGGCTGCCTGGGAGGGGGAGATGCTCACGTTTG
TGTAGACTGCGTAGACTGGTTGGCGAAGGCAGCATTGGGTTCTAGGAGTCTTGGTATCTCATTG
CCTGTCCCCCTGAGGGGTGGGCAGAGGGTCTGGGGTCCCTGCTTTCTGCAGAAGCAAATGACTA
AGTAGGCAGGATGGAGGGGGGCCTCCACCCAGGCTCTTACGTAGGGCTTGTGGGCAGGCTGATG
GTGTCCTTCCGCCAGCACCTCCATCCTCACCCCTAGAGTCTGACCCAGAAAGTTCCAGGGTGTG
AGCAGAGAATAGGACCCTGGTTCACTTCTGCTAGTGGATCAGCCTCCGTGCCCCCAACCGGCCC
TCCCGTGAAGTGTTGGCAGGTGGTAGAGGAGCTGTGGCCACAGACTTTCACAGGGTGGGCCTTG
CGCAGTCCAGCTCATCTGCCCCTACCTTTACCTGCTGTCACCGGCCAGAACCCTGCTCTCTCTT
TAGAGCGCTGTGGGACCTCGGAGTGAGGGCAGGTGGAGAGGAGAGCCAGAATCCAGCCGTTGTG
GAGAATCTGGCCCCGGGGGTCTTCCGAGAGCATTCTCCAGGTGCTGCATGGGCCTGGCCTGTCC
CCACTCCCACCATTTGCCTTCAGCCTCTGGTGACTCAACGGCCCTTCTCCCTGGAGGAGACACC
TCAGGGAGCCTGCTCTGTGACTGTCACTCCCATCCTACCACCTGCAACCGAGGGACACTCCTGC
ATTCTTACTCCACCCTGGGAGCCATCAAGAACTGTCCCTCTCGGAGTTCCTGCTGTGGTGCAGT
GCGATCAGCGGTGTCTCTGGAGCGCTGGGATGCAGGTTCGATCCCTGGCCCAGTGCAGTGGGTT
AAGGATCCAGCAGCACTGCTGTAGCATAGGTAGCAACTGTGCCTCGGATCTGATCCCTGGCCGG
GGAACTCCATATGCCATTAGGGGCGGGGGGGGGGGCAAAAAAAAAAAGAACTGTCCCTCTGGCT
TCTAGCAGGCCATGGCCAATCTGTGTTCTGTGGCTGTTGCGTTGGTGGATAATTAGAAACATGG
CTTTTACAAATGCA

hide sequence

RefSeq Acc Id:

XM_013989998 ⟹ XP_013845452

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	47,717,898 - 47,736,468 (-)	NCBI

Sequence:

show sequence

CATACATGTCGTGACGTGGAACGTGGCCTCTGCAGCACCCCCTCCAGACCTCAGTGATCTGCTC
CAGCTGCACACCCCGAACCTGAATCTGGACGTGTATGTCATTGGGAAATGAACTGTGGGATCAT
GAGCCTCCTTTCTGACACTGCCTTTGAAGACCCGTGGAGCAGTTTCTTCATGGATGTGCTTTCC
CCTCTGAGCTTCGTCAAGGTCTCCAGCGTCCGCATGCAGGGGCTCCTCTTACTGGTATTTGCCA
AGTACCAGCATTTGCCCTTTATCCAGATCCTCTCTGCTAAATCCACCCCCACTGGCCTCTTCGG
GTATTGGGGGAACAAAGGGGGCGTCAACATATTCCTGAAGCTCTACGGCTACTACGTCAGCATC
ATCAACTGCCACCTGCCCCCACATATGGCCAATAATGACCAGCGGCTGGAGCATTTTGACCGGA
TCCTGGAGATGCAGAATTTTGAGGCACAGGATATCCCCAACATCCTGGACCACGACCTCATTCT
CTGGTTTGGAGACATGAACTTTCGGATCGAGGACTTTGGGTTGCACTTTGTTCGGGAATCCATA
AAACATCAGTGCTACAGTGACCTGTGGGAGAAGGATCAGCTCAGCATTGCCAAGAGACATGACC
CTCTGCTCCGGGAGTTCCAGGAGGGACCCCTGCTCTTCCCGCCCACCTACAAGTTCGATAAGAA
CTCCAACAACTATGACACAAGTGAGAAAAAACGCAAGCCTGCGTGGACCGACCGCATCCTTTGG
AGGTTGAAGCGGCAGCCCCAGGCCGACTGCCACCCCCCCACACTGCCAGGGCCCCACTTCTCCC
TGGTTCTGAGGAGCTACGTCAGCCACATGATGTACAGCATCAGTGACCACAAGCCTGTCACCGG
CACCTTTGACTTGGAGCTGAAGCCGCTGGTATCTGCTCCGCTGATCACCCTGCTCCCCGAGGGC
CCGTGTACCACCGAGAGCGACCTGCTCATCAGCTACTCCCTGGCCTCGGACTTCCTCAGCAGCC
CCTGGGACTGGATCGGACTGTACAAGGTGGGGCTGCGCCACATTAATGACTATGTGTCATATGT
CTGGGTCGGGGACAACCAGGTCTCCTTCGGCGACCAGCTGAACCAGGTATACATCAGCCTCAGC
GACATCCCTGAGACTGAGGATGGGTTTCTCCTCTTTTACTATAGCAACAGCCTGCGTTCTGTGG
TGGGGATAAGCAGACCCTTCAAGATCCAGCCTCGCTCCTTCCTGGAGCAGGACTCACTGGATGA
AGCCCAACCACAGATCTGAGCCAGGATGCGAGTGAACCCGGGCGGAGGCCGGCGCTGGCTGCCA
GCTCTGCCTTCACTGCCAGGAGCACTGGGGGCCCAGCCCTGCCCCCTGAGGAGGCTGCAAGTCT
CCTCCACCTCCCAGGGCGAGTTCTAGCCACACTCCCTCCCTCTCCGCAGTCCAGATCTCCAGGA
TCAGCCCCTTCAATACAGGTTTCTGTGGCTCAGGTGTGAGTGAAACCAGCTAGTTTGTCAGCAG
TGAAGCTCTAGACAGTCCGCTGGAGGAAGGACCCTCCAGCTTGCATCTCATTTCTCCATCTTCC
CCACACACACACTTGTAGTCCTGCCCAAGCAGGCCTGCCGGGCACATGCCCCATCTGGCACAGG
CCCGCATTCTTGTCACGCCACCCTGGGCCTTAGGCTGCCTGGGAGGGGGAGATGCTCACGTTTG
TGTAGACTGCGTAGACTGGTTGGCGAAGGCAGCATTGGGTTCTAGGAGTCTTGGTATCTCATTG
CCTGTCCCCCTGAGGGGTGGGCAGAGGGTCTGGGGTCCCTGCTTTCTGCAGAAGCAAATGACTA
AGTAGGCAGGATGGAGGGGGGCCTCCACCCAGGCTCTTACGTAGGGCTTGTGGGCAGGCTGATG
GTGTCCTTCCGCCAGCACCTCCATCCTCACCCCTAGAGTCTGACCCAGAAAGTTCCAGGGTGTG
AGCAGAGAATAGGACCCTGGTTCACTTCTGCTAGTGGATCAGCCTCCGTGCCCCCAACCGGCCC
TCCCGTGAAGTGTTGGCAGGTGGTAGAGGAGCTGTGGCCACAGACTTTCACAGGGTGGGCCTTG
CGCAGTCCAGCTCATCTGCCCCTACCTTTACCTGCTGTCACCGGCCAGAACCCTGCTCTCTCTT
TAGAGCGCTGTGGGACCTCGGAGTGAGGGCAGGTGGAGAGGAGAGCCAGAATCCAGCCGTTGTG
GAGAATCTGGCCCCGGGGGTCTTCCGAGAGCATTCTCCAGGTGCTGCATGGGCCTGGCCTGTCC
CCACTCCCACCATTTGCCTTCAGCCTCTGGTGACTCAACGGCCCTTCTCCCTGGAGGAGACACC
TCAGGGAGCCTGCTCTGTGACTGTCACTCCCATCCTACCACCTGCAACCGAGGGACACTCCTGC
ATTCTTACTCCACCCTGGGAGCCATCAAGAACTGTCCCTCTCGGAGTTCCTGCTGTGGTGCAGT
GCGATCAGCGGTGTCTCTGGAGCGCTGGGATGCAGGTTCGATCCCTGGCCCAGTGCAGTGGGTT
AAGGATCCAGCAGCACTGCTGTAGCATAGGTAGCAACTGTGCCTCGGATCTGATCCCTGGCCGG
GGAACTCCATATGCCATTAGGGGCGGGGGGGGGGGCAAAAAAAAAAAGAACTGTCCCTCTGGCT
TCTAGCAGGCCATGGCCAATCTGTGTTCTGTGGCTGTTGCGTTGGTGGATAATTAGAAACATGG
CTTTTACAAATGCA

hide sequence

RefSeq Acc Id:

XM_021066068 ⟹ XP_020921727

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	47,717,898 - 47,738,540 (-)	NCBI

Sequence:

show sequence

CCCGCCTCTTCCCCCGGGCCGCGCCACCCAGAGCCTTCCGTGCGCCTAGGCCCCGCCTCTTACG
GAAGCCGAGGCGGAGGGTCGGAATCCGGAAGAAAAACAATCGAGCGAGTGAGCTGACCGGCACC
TGCTACCCGATCGGGACAGATCAAGCCAGGATCCGCTGAGGCTGGGAGACGCGAACCAGCCGGG
GCACCGCGTGGGAACGATGGCTGCCACGAACCCCCAGACCGAACCGAGAAGCAGGACGCTCAGC
ATACATGTCGTGACGTGGAACGTGGCCTCTGCAGCACCCCCTCCAGACCTCAGTGATCTGCTCC
AGCTGCACACCCCGAACCTGAATCTGGACGTGTATGTCATTGGTTTGCAGGAAATGAACTGTGG
GATCATGAGCCTCCTTTCTGACACTGCCTTTGAAGACCCGTGGAGCAGTTTCTTCATGGATGTG
CTTTCCCCTCTGAGCTTCGTCAAGGTCTCCAGCGTCCGCATGCAGGGGCTCCTCTTACTGGTAT
TTGCCAAGTACCAGCATTTGCCCTTTATCCAGATCCTCTCTGCTAAATCCACCCCCACTGGCCT
CTTCGGGTATTGGGGGAACAAAGGGGGCGTCAACATATTCCTGAAGCTCTACGGCTACTACGTC
AGCATCATCAACTGCCACCTGCCCCCACATATGGCCAATAATGACCAGCGGCTGGAGCATTTTG
ACCGGATCCTGGAGATGCAGAATTTTGAGGCACAGGATATCCCCAACATCCTGGACCACGACCT
CATTCTCTGGTTTGGAGACATGAACTTTCGGATCGAGGACTTTGGGTTGCACTTTGTTCGGGAA
TCCATAAAACATCAGTGCTACAGTGACCTGTGGGAGAAGGATCAGCTCAGCATTGCCAAGAGAC
ATGACCCTCTGCTCCGGGAGTTCCAGGAGGGACCCCTGCTCTTCCCGCCCACCTACAAGTTCGA
TAAGAACTCCAACAACTATGACACAAGTGAGAAAAAACGCAAGCCTGCGTGGACCGACCGCATC
CTTTGGAGGTTGAAGCGGCAGCCCCAGGCCGACTGCCACCCCCCCACACTGCCAGGGCCCCACT
TCTCCCTGGTTCTGAGGAGCTACGTCAGCCACATGATGTACAGCATCAGTGACCACAAGCCTGT
CACCGGCACCTTTGACTTGGAGCTGAAGCCGCTGGTATCTGCTCCGCTGATCACCCTGCTCCCC
GAGGGCCCGTGTACCACCGAGAGCGACCTGCTCATCAGCTACTCCCTGGCCTCGGACTTCCTCA
GCAGCCCCTGGGACTGGATCGGACTGTACAAGGTGGGGCTGCGCCACATTAATGACTATGTGTC
ATATGTCTGGGTCGGGGACAACCAGGTCTCCTTCGGCGACCAGCTGAACCAGGTACCTGCCCCC
TCTCCTGAGCTAGGTGTTCCGCGCCTCCAGCAGGTAGGCTTGCCTGAGGGCTGCTGTCTTCTGG
AAGGAACAGAGCCAGTTTCCCTTGTCACTGAGAGCTGGGCCTGGGGCTGTGGGCCTGACCCCCT
TCCTGTCTGTCCCCGCCCCCACAGGTATACATCAGCCTCAGCGACATCCCTGAGACTGAGGATG
GGTTTCTCCTCTTTTACTATAGCAACAGCCTGCGTTCTGTGGTGGGGATAAGCAGACCCTTCAA
GATCCAGCCTCGCTCCTTCCTGGAGCAGGACTCACTGGATGAAGCCCAACCACAGATCTGAGCC
AGGATGCGAGTGAACCCGGGCGGAGGCCGGCGCTGGCTGCCAGCTCTGCCTTCACTGCCAGGAG
CACTGGGGGCCCAGCCCTGCCCCCTGAGGAGGCTGCAAGTCTCCTCCACCTCCCAGGGCGAGTT
CTAGCCACACTCCCTCCCTCTCCGCAGTCCAGATCTCCAGGATCAGCCCCTTCAATACAGGTTT
CTGTGGCTCAGGTGTGAGTGAAACCAGCTAGTTTGTCAGCAGTGAAGCTCTAGACAGTCCGCTG
GAGGAAGGACCCTCCAGCTTGCATCTCATTTCTCCATCTTCCCCACACACACACTTGTAGTCCT
GCCCAAGCAGGCCTGCCGGGCACATGCCCCATCTGGCACAGGCCCGCATTCTTGTCACGCCACC
CTGGGCCTTAGGCTGCCTGGGAGGGGGAGATGCTCACGTTTGTGTAGACTGCGTAGACTGGTTG
GCGAAGGCAGCATTGGGTTCTAGGAGTCTTGGTATCTCATTGCCTGTCCCCCTGAGGGGTGGGC
AGAGGGTCTGGGGTCCCTGCTTTCTGCAGAAGCAAATGACTAAGTAGGCAGGATGGAGGGGGGC
CTCCACCCAGGCTCTTACGTAGGGCTTGTGGGCAGGCTGATGGTGTCCTTCCGCCAGCACCTCC
ATCCTCACCCCTAGAGTCTGACCCAGAAAGTTCCAGGGTGTGAGCAGAGAATAGGACCCTGGTT
CACTTCTGCTAGTGGATCAGCCTCCGTGCCCCCAACCGGCCCTCCCGTGAAGTGTTGGCAGGTG
GTAGAGGAGCTGTGGCCACAGACTTTCACAGGGTGGGCCTTGCGCAGTCCAGCTCATCTGCCCC
TACCTTTACCTGCTGTCACCGGCCAGAACCCTGCTCTCTCTTTAGAGCGCTGTGGGACCTCGGA
GTGAGGGCAGGTGGAGAGGAGAGCCAGAATCCAGCCGTTGTGGAGAATCTGGCCCCGGGGGTCT
TCCGAGAGCATTCTCCAGGTGCTGCATGGGCCTGGCCTGTCCCCACTCCCACCATTTGCCTTCA
GCCTCTGGTGACTCAACGGCCCTTCTCCCTGGAGGAGACACCTCAGGGAGCCTGCTCTGTGACT
GTCACTCCCATCCTACCACCTGCAACCGAGGGACACTCCTGCATTCTTACTCCACCCTGGGAGC
CATCAAGAACTGTCCCTCTCGGAGTTCCTGCTGTGGTGCAGTGCGATCAGCGGTGTCTCTGGAG
CGCTGGGATGCAGGTTCGATCCCTGGCCCAGTGCAGTGGGTTAAGGATCCAGCAGCACTGCTGT
AGCATAGGTAGCAACTGTGCCTCGGATCTGATCCCTGGCCGGGGAACTCCATATGCCATTAGGG
GCGGGGGGGGGGGCAAAAAAAAAAAGAACTGTCCCTCTGGCTTCTAGCAGGCCATGGCCAATCT
GTGTTCTGTGGCTGTTGCGTTGGTGGATAATTAGAAACATGGCTTTTACAAATGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001177221	(Get FASTA)	NCBI Sequence Viewer
	XP_005657070	(Get FASTA)	NCBI Sequence Viewer
	XP_013845452	(Get FASTA)	NCBI Sequence Viewer
	XP_020921727	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ADE62527	(Get FASTA)	NCBI Sequence Viewer
	ADE62528	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_020921727 ⟸ XM_021066068

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAATNPQTEPRSRTLSIHVVTWNVASAAPPPDLSDLLQLHTPNLNLDVYVIGLQEMNCGIMSLL
SDTAFEDPWSSFFMDVLSPLSFVKVSSVRMQGLLLLVFAKYQHLPFIQILSAKSTPTGLFGYWG
NKGGVNIFLKLYGYYVSIINCHLPPHMANNDQRLEHFDRILEMQNFEAQDIPNILDHDLILWFG
DMNFRIEDFGLHFVRESIKHQCYSDLWEKDQLSIAKRHDPLLREFQEGPLLFPPTYKFDKNSNN
YDTSEKKRKPAWTDRILWRLKRQPQADCHPPTLPGPHFSLVLRSYVSHMMYSISDHKPVTGTFD
LELKPLVSAPLITLLPEGPCTTESDLLISYSLASDFLSSPWDWIGLYKVGLRHINDYVSYVWVG
DNQVSFGDQLNQVPAPSPELGVPRLQQVGLPEGCCLLEGTEPVSLVTESWAWGCGPDPLPVCPR
PHRYTSASATSLRLRMGFSSFTIATACVLWWG

hide sequence

RefSeq Acc Id:

XP_005657070 ⟸ XM_005657013

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAATNPQTEPRSRTLSIHVVTWNVASAAPPPDLSDLLQLHTPNLNLDVYVIGLQEMNCGIMSLL
SDTAFEDPWSSFFMDVLSPLSFVKVSSVRMQGLLLLVFAKYQHLPFIQILSAKSTPTGLFGYWG
NKGGVNIFLKLYGYYVSIINCHLPPHMANNDQRLEHFDRILEMQNFEAQDIPNILDHDLILWFG
DMNFRIEDFGLHFVRESIKHQCYSDLWEKDQLSIAKRHDPLLREFQEGPLLFPPTYKFDKNSNN
YDTSEKKRKPAWTDRILWRLKRQPQADCHPPTLPGPHFSLVLRSYVSHMMYSISDHKPVTGTFD
LELKPLVSAPLITLLPEGPCTTESDLLISYSLASDFLSSPWDWIGLYKVGLRHINDYVSYVWVG
DNQVSFGDQLNQQQPAFCGGDKQTLQDPASLLPGAGLTG

hide sequence

RefSeq Acc Id:

XP_013845452 ⟸ XM_013989998

- Peptide Label:

isoform X3

- Sequence:

show sequence

MNCGIMSLLSDTAFEDPWSSFFMDVLSPLSFVKVSSVRMQGLLLLVFAKYQHLPFIQILSAKST
PTGLFGYWGNKGGVNIFLKLYGYYVSIINCHLPPHMANNDQRLEHFDRILEMQNFEAQDIPNIL
DHDLILWFGDMNFRIEDFGLHFVRESIKHQCYSDLWEKDQLSIAKRHDPLLREFQEGPLLFPPT
YKFDKNSNNYDTSEKKRKPAWTDRILWRLKRQPQADCHPPTLPGPHFSLVLRSYVSHMMYSISD
HKPVTGTFDLELKPLVSAPLITLLPEGPCTTESDLLISYSLASDFLSSPWDWIGLYKVGLRHIN
DYVSYVWVGDNQVSFGDQLNQVYISLSDIPETEDGFLLFYYSNSLRSVVGISRPFKIQPRSFLE
QDSLDEAQPQI

hide sequence

RefSeq Acc Id:

NP_001177221 ⟸ NM_001190292

- UniProtKB:

D7P0F2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAATNPQTEPRSRTLSIHVATWNVASAAPPPDLSDLLQLHTPNLNLDVYVIGLQEMNCGIMSLL
SDTAFEDPWSSFFMDVLSPLSFVKVSSVRMQGLLLLVFAKYQHLPFIQILSAKSTPTGLFGYWG
NKGGVNIFLKLYGYYVSIINCHLPPHMANNDQRLEHFDRILEMQNFEAQDIPNILDHDLILWFG
DMNFRIEDFGLHFVRESIKHQCYSDLWEKDQLSIAKRHDPLLREFQEGPLLFPPTYKFDKNSNN
YDTSEKKRKPAWTDRILWRLKRQPQADCHPPTLPAPHFSLVLRSYVSHMMYSISDHKPVTGTFD
LELKPLVSAPLITLLPEGPCTTESDLLISYSLASDFLSSPWDWIGLYKVGLRHINDYVSYVWVG
DNQVSFGDQLNQVYISLSDIPETEDGFLLFYYSNSLRSVVGISRPFKIQPRSFLEQDSLDEAQP
QI

hide sequence

RefSeq Acc Id:

ENSSSCP00000025324 ⟸ ENSSSCT00000030655

RefSeq Acc Id:

ENSSSCP00000024039 ⟸ ENSSSCT00000030204

RefSeq Acc Id:

ENSSSCP00000069238 ⟸ ENSSSCT00000075492

RefSeq Acc Id:

ENSSSCP00000070231 ⟸ ENSSSCT00000091212

Protein Domains

IPPc

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000030707	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00070014442	UniProtKB/TrEMBL
Ensembl Protein	ENSSSCP00000024039	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCP00000025324	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCP00000069238	UniProtKB/TrEMBL
	ENSSSCP00000070231	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCP00070023665	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000030204	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCT00000030655	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCT00000075492	UniProtKB/TrEMBL
	ENSSSCT00000091212	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCT00070028411	UniProtKB/TrEMBL
Gene3D-CATH	3.60.10.10	UniProtKB/TrEMBL
InterPro	Endo/exonu/phosph_ase_sf	UniProtKB/TrEMBL
	Endo/exonuclease/phosphatase	UniProtKB/TrEMBL
	IPPc	UniProtKB/TrEMBL
	SKICH	UniProtKB/TrEMBL
KEGG Report	ssc:100462756	UniProtKB/TrEMBL
NCBI Gene	INPP5K	ENTREZGENE
Pfam	Exo_endo_phos	UniProtKB/TrEMBL
	SKICH	UniProtKB/TrEMBL
SMART	IPPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56219	UniProtKB/TrEMBL
UniProt	A0A4X1U725_PIG	UniProtKB/TrEMBL
	A0A5G2QYL7_PIG	UniProtKB/TrEMBL
	A0A5G2QZB5_PIG	UniProtKB/TrEMBL
	D7P0F2	ENTREZGENE, UniProtKB/TrEMBL
	I3LIY2_PIG	UniProtKB/TrEMBL
	I3LMK3_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:89147	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - OMIM