Atoh1 (atonal bHLH transcription factor 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Atoh1 (atonal bHLH transcription factor 1) Mus musculus
Analyze
Symbol: Atoh1
Name: atonal bHLH transcription factor 1
RGD ID: 1558062
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Involved in negative regulation of gliogenesis; positive regulation of inner ear receptor cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including generation of neurons; neuroblast migration; and positive regulation of inner ear auditory receptor cell differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; inner ear; and skin. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Orthologous to human ATOH1 (atonal bHLH transcription factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: atonal homolog 1; bHLHa; bHLHa14; Hath; Hath1; helix-loop-helix protein mATH-1; Math; MATH-1; Math1; protein atonal homolog 1; transcription factor Atoh1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39664,706,109 - 64,708,229 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl664,706,109 - 64,708,229 (+)EnsemblGRCm39 Ensembl
GRCm38664,729,125 - 64,731,245 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl664,729,125 - 64,731,245 (+)EnsemblGRCm38mm10GRCm38
MGSCv37664,679,140 - 64,681,237 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36664,658,735 - 64,660,821 (+)NCBIMGSCv36mm8
Celera666,856,661 - 66,858,758 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal brain development  (IAGP)
abnormal cerebellar Purkinje cell layer  (IAGP)
abnormal cerebellum external granule cell layer morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cochlear hair cell morphology  (IAGP)
abnormal cochlear VIII nucleus morphology  (IAGP)
abnormal distortion product otoacoustic emission  (IAGP)
abnormal gait  (IAGP)
abnormal glutaminergic neuron morphology  (IAGP)
abnormal hindbrain development  (IAGP)
abnormal mechanical nociception  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal pinna reflex  (IAGP)
abnormal small intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal vestibular hair cell morphology  (IAGP)
abnormal vestibular hair cell stereociliary bundle morphology  (IAGP)
absent cerebellar foliation  (IAGP)
absent cochlear hair cells  (IAGP)
absent vestibular hair cells  (IAGP)
cerebellum atrophy  (IAGP)
cochlear hair cell degeneration  (IAGP)
cochlear inner hair cell degeneration  (IAGP)
cochlear outer hair cell degeneration  (IAGP)
cyanosis  (IAGP)
deafness  (IAGP)
decreased inner hair cell stereocilia number  (IAGP)
decreased neuronal precursor proliferation  (IAGP)
decreased outer hair cell stereocilia number  (IAGP)
decreased pulmonary respiratory rate  (IAGP)
impaired hearing  (IAGP)
impaired intestine regeneration  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
irregular external granule cell layer thickness  (IAGP)
neonatal lethality  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
respiratory failure  (IAGP)
small cerebellum  (IAGP)
thin external granule cell layer  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7721778   PMID:7744035   PMID:8543157   PMID:8872459   PMID:8938455   PMID:8948587   PMID:9060409   PMID:9253602   PMID:9353119   PMID:9367153   PMID:9383293   PMID:9389662  
PMID:9449674   PMID:9808626   PMID:10349636   PMID:10364557   PMID:10383648   PMID:10409504   PMID:10464095   PMID:10615124   PMID:10640713   PMID:10648228   PMID:10662643   PMID:10683172  
PMID:10693795   PMID:10693804   PMID:10837126   PMID:10952903   PMID:11023859   PMID:11032813   PMID:11042159   PMID:11071781   PMID:11076861   PMID:11134349   PMID:11217851   PMID:11312603  
PMID:11395003   PMID:11412999   PMID:11425898   PMID:11489994   PMID:11498051   PMID:11500373   PMID:11502254   PMID:11591219   PMID:11739954   PMID:11784856   PMID:11807030   PMID:11877374  
PMID:11891983   PMID:11918690   PMID:11944941   PMID:11973280   PMID:12091320   PMID:12091321   PMID:12194867   PMID:12208538   PMID:12223565   PMID:12358782   PMID:12372255   PMID:12435358  
PMID:12441305   PMID:12456641   PMID:12466851   PMID:12477932   PMID:12584723   PMID:12717441   PMID:12741987   PMID:12915300   PMID:14507778   PMID:14681479   PMID:14757642   PMID:14999071  
PMID:15044550   PMID:15056720   PMID:15084464   PMID:15148302   PMID:15163631   PMID:15183721   PMID:15183722   PMID:15186480   PMID:15229603   PMID:15254021   PMID:15469980   PMID:15483558  
PMID:15489334   PMID:15496441   PMID:15543141   PMID:15618518   PMID:15691760   PMID:15741322   PMID:15769945   PMID:15788454   PMID:15788459   PMID:15843406   PMID:15844198   PMID:15846349  
PMID:16039563   PMID:16061358   PMID:16141072   PMID:16141073   PMID:16145668   PMID:16145671   PMID:16202705   PMID:16202707   PMID:16230531   PMID:16262623   PMID:16289327   PMID:16325379  
PMID:16354937   PMID:16364898   PMID:16406324   PMID:16407553   PMID:16510500   PMID:16537572   PMID:16571630   PMID:16602821   PMID:16651541   PMID:16679559   PMID:16691564   PMID:16728479  
PMID:16736472   PMID:16782087   PMID:16790481   PMID:16831200   PMID:16849540   PMID:16957075   PMID:16971476   PMID:17049261   PMID:17117437   PMID:17122047   PMID:17150208   PMID:17151198  
PMID:17166916   PMID:17257418   PMID:17295842   PMID:17319963   PMID:17321515   PMID:17360405   PMID:17397818   PMID:17409257   PMID:17442811   PMID:17488627   PMID:17504941   PMID:17553984  
PMID:17570220   PMID:17604700   PMID:17664423   PMID:17681138   PMID:17728348   PMID:17804638   PMID:17823936   PMID:17826772   PMID:17878293   PMID:17893320   PMID:17900924   PMID:17928434  
PMID:17961150   PMID:18039969   PMID:18054549   PMID:18186922   PMID:18198335   PMID:18212062   PMID:18272594   PMID:18287559   PMID:18291358   PMID:18302773   PMID:18430530   PMID:18448648  
PMID:18480159   PMID:18498101   PMID:18524904   PMID:18536717   PMID:18557763   PMID:18590716   PMID:18619852   PMID:18632939   PMID:18652815   PMID:18723012   PMID:18829970   PMID:19011097  
PMID:19029045   PMID:19088088   PMID:19135992   PMID:19154718   PMID:19181188   PMID:19185848   PMID:19243219   PMID:19439493   PMID:19515912   PMID:19541997   PMID:19542352   PMID:19549527  
PMID:19598246   PMID:19603509   PMID:19609565   PMID:19668217   PMID:19741118   PMID:19741143   PMID:19782676   PMID:19786015   PMID:19786578   PMID:19864427   PMID:19908278   PMID:19914183  
PMID:19940179   PMID:19965762   PMID:20017954   PMID:20059953   PMID:20080794   PMID:20081195   PMID:20131355   PMID:20186345   PMID:20206242   PMID:20211142   PMID:20388655   PMID:20418906  
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PMID:22279587   PMID:22292060   PMID:22307612   PMID:22340499   PMID:22354878   PMID:22355124   PMID:22370000   PMID:22370966   PMID:22399751   PMID:22422267   PMID:22513377   PMID:22526732  
PMID:22543087   PMID:22573682   PMID:22573692   PMID:22586121   PMID:22609550   PMID:22694344   PMID:22808246   PMID:22817342   PMID:22922422   PMID:22958821   PMID:22973011   PMID:22998872  
PMID:23177959   PMID:23193000   PMID:23225629   PMID:23266329   PMID:23318633   PMID:23408898   PMID:23428873   PMID:23459943   PMID:23533177   PMID:23589895   PMID:23614009   PMID:23673330  
PMID:23673358   PMID:23761906   PMID:23783432   PMID:23796904   PMID:23828563   PMID:23877428   PMID:23918393   PMID:23946445   PMID:24141309   PMID:24146773   PMID:24184637   PMID:24265785  
PMID:24335253   PMID:24381197   PMID:24413398   PMID:24431450   PMID:24465223   PMID:24491816   PMID:24550288   PMID:24565836   PMID:24695699   PMID:24715462   PMID:24717432   PMID:24717433  
PMID:24842997   PMID:24929016   PMID:24946904   PMID:24952961   PMID:24983448   PMID:24995796   PMID:25050931   PMID:25057208   PMID:25209290   PMID:25224259   PMID:25232121   PMID:25378482  
PMID:25468937   PMID:25490446   PMID:25535395   PMID:25535838   PMID:25624394   PMID:25818302   PMID:25855195   PMID:25866925   PMID:25873862   PMID:25904789   PMID:26015562   PMID:26023187  
PMID:26092122   PMID:26131556   PMID:26138479   PMID:26139524   PMID:26209643   PMID:26224861   PMID:26274331   PMID:26302206   PMID:26517967   PMID:26527010   PMID:26549569   PMID:26680304  
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PMID:27559308   PMID:27564589   PMID:27581449   PMID:27609139   PMID:27633988   PMID:27751776   PMID:27829143   PMID:27917898   PMID:27923395   PMID:27966429   PMID:28030585   PMID:28263708  
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PMID:28729444   PMID:28870992   PMID:28892484   PMID:29031500   PMID:29107558   PMID:29138055   PMID:29139542   PMID:29153838   PMID:29168692   PMID:29212024   PMID:29225067   PMID:29233556  
PMID:29317485   PMID:29321651   PMID:29386106   PMID:29545196   PMID:29724954   PMID:29769265   PMID:29879109   PMID:29899403   PMID:29967482   PMID:29972353   PMID:30008200   PMID:30055169  
PMID:30063705   PMID:30100168   PMID:30247156   PMID:30302725   PMID:30305733   PMID:30338292   PMID:30415995   PMID:30455179   PMID:30470704   PMID:30487221   PMID:30538199   PMID:30618612  
PMID:30635334   PMID:30651295   PMID:30695697   PMID:30758073   PMID:30794158   PMID:30862721   PMID:30929920   PMID:31001589   PMID:31033441   PMID:31185200   PMID:31187730   PMID:31231046  
PMID:31291569   PMID:31292434   PMID:31330316   PMID:31442404   PMID:31676552   PMID:31751832   PMID:31843520   PMID:31851932   PMID:31869353   PMID:31930988   PMID:31932950   PMID:31959916  
PMID:31983537   PMID:32047912   PMID:32084390   PMID:32179676   PMID:32183943   PMID:32205193   PMID:32234638   PMID:32492419   PMID:32553121   PMID:32554568   PMID:32665354   PMID:32880858  
PMID:32896624   PMID:32907846   PMID:33082319   PMID:33246067   PMID:33253789   PMID:33293609   PMID:33382037   PMID:33468540   PMID:33475140   PMID:33524475   PMID:33591268   PMID:33770497  
PMID:33789110   PMID:33882317   PMID:33892704   PMID:34003106   PMID:34031166   PMID:34057742   PMID:34107249   PMID:34210780   PMID:34235739   PMID:34244441   PMID:34260939   PMID:34266958  
PMID:34331868   PMID:34542409   PMID:34686336   PMID:34728601   PMID:34746154   PMID:34789880   PMID:34857649   PMID:35038200   PMID:35044072   PMID:35081371   PMID:35238644   PMID:35363520  
PMID:35508658   PMID:35551236   PMID:35731926   PMID:35925886   PMID:35935334   PMID:36187289   PMID:36252002   PMID:36334588   PMID:36394266   PMID:36445327   PMID:36495874   PMID:36720468  
PMID:36810133   PMID:36942864   PMID:37028407   PMID:37171961   PMID:37188723   PMID:37390208   PMID:37585469   PMID:37738262   PMID:37824217   PMID:37923392   PMID:37982489   PMID:38078650  
PMID:38079436   PMID:38176908   PMID:38246872   PMID:38627062   PMID:38688721   PMID:38733584   PMID:38742226   PMID:38834071   PMID:38896627   PMID:39106860   PMID:39261625   PMID:39448563  


Genomics

Comparative Map Data
Atoh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39664,706,109 - 64,708,229 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl664,706,109 - 64,708,229 (+)EnsemblGRCm39 Ensembl
GRCm38664,729,125 - 64,731,245 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl664,729,125 - 64,731,245 (+)EnsemblGRCm38mm10GRCm38
MGSCv37664,679,140 - 64,681,237 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36664,658,735 - 64,660,821 (+)NCBIMGSCv36mm8
Celera666,856,661 - 66,858,758 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.03NCBI
ATOH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38493,828,753 - 93,830,964 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl493,828,753 - 93,830,964 (+)EnsemblGRCh38hg38GRCh38
GRCh37494,749,904 - 94,752,115 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36494,969,101 - 94,970,165 (+)NCBINCBI36Build 36hg18NCBI36
Build 34495,107,255 - 95,108,320NCBI
Celera492,046,181 - 92,047,245 (+)NCBICelera
Cytogenetic Map4q22.2NCBI
HuRef490,487,368 - 90,488,432 (+)NCBIHuRef
CHM1_1494,726,590 - 94,727,654 (+)NCBICHM1_1
T2T-CHM13v2.0497,144,124 - 97,146,335 (+)NCBIT2T-CHM13v2.0
Atoh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8495,241,933 - 95,244,028 (+)NCBIGRCr8
mRatBN7.2493,912,068 - 93,914,163 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl493,912,068 - 93,914,154 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx499,138,821 - 99,140,918 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0494,913,774 - 94,915,871 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0493,336,612 - 93,338,707 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0495,498,003 - 95,500,098 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl495,498,003 - 95,500,089 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04160,284,441 - 160,286,536 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4494,109,650 - 94,111,745 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera488,659,055 - 88,661,150 (+)NCBICelera
Cytogenetic Map4q31NCBI
Atoh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554054,461,704 - 4,462,756 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554054,461,704 - 4,462,756 (+)NCBIChiLan1.0ChiLan1.0
ATOH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2391,853,914 - 91,856,688 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1492,132,530 - 92,135,303 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0486,188,534 - 86,191,301 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1496,863,733 - 96,864,905 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl496,863,762 - 96,864,832 (+)Ensemblpanpan1.1panPan2
ATOH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13216,807,217 - 16,809,294 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3216,807,336 - 16,808,406 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3225,139,203 - 25,141,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03216,985,533 - 16,987,838 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3216,985,749 - 16,986,819 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13216,957,560 - 16,959,866 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03216,773,311 - 16,775,500 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03223,118,806 - 23,121,117 (-)NCBIUU_Cfam_GSD_1.0
Atoh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530124,908,942 - 24,911,175 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366871,436,009 - 1,437,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366871,435,977 - 1,437,138 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATOH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8125,768,286 - 125,770,545 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18125,768,232 - 125,770,619 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28135,103,515 - 135,105,739 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATOH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1742,098,057 - 42,104,910 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl742,100,996 - 42,102,060 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603720,456,111 - 20,458,324 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atoh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475721,517,809 - 21,518,864 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475721,517,650 - 21,519,543 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:210
Count of miRNA genes:185
Interacting mature miRNAs:200
Transcripts:ENSMUST00000101351
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
15039373Adip28_madiposity 28 (mouse)65628519490285194Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65628519490285194Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66003466394034782Mouse

Markers in Region
BB385668  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,731,097 - 64,731,196UniSTSGRCm38
MGSCv37664,681,091 - 64,681,190UniSTSGRCm37
Celera666,858,612 - 66,858,711UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.69UniSTS
Whitehead/MRC_RH6654.25UniSTS
D43694  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,730,434 - 64,730,513UniSTSGRCm38
MGSCv37664,680,428 - 64,680,507UniSTSGRCm37
Celera666,857,949 - 66,858,028UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.69UniSTS
Whitehead_YAC6 UniSTS
Atoh1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6C1UniSTS
cM Map630.03UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000101351   ⟹   ENSMUSP00000098903
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl664,706,109 - 64,708,229 (+)Ensembl
GRCm38.p6 Ensembl664,729,125 - 64,731,245 (+)Ensembl
RefSeq Acc Id: NM_007500   ⟹   NP_031526
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39664,706,109 - 64,708,229 (+)NCBI
GRCm38664,729,125 - 64,731,245 (+)NCBI
MGSCv37664,679,140 - 64,681,237 (+)RGD
Celera666,856,661 - 66,858,758 (+)RGD
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_031526 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH10820 (Get FASTA)   NCBI Sequence Viewer  
  AAH51256 (Get FASTA)   NCBI Sequence Viewer  
  BAA07791 (Get FASTA)   NCBI Sequence Viewer  
  EDK98770 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000098903
  ENSMUSP00000098903.5
GenBank Protein P48985 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_031526   ⟸   NM_007500
- UniProtKB: P48985 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000098903   ⟸   ENSMUST00000101351
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P48985-F1-model_v2 AlphaFold P48985 1-351 view protein structure

Promoters
RGD ID:6838960
Promoter ID:MM_KWN:46230
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:NM_007500
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36664,679,509 - 64,680,009 (+)MPROMDB
RGD ID:6889886
Promoter ID:EPDNEW_M8394
Type:single initiation site
Name:Atoh1_1
Description:Mus musculus atonal bHLH transcription factor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38664,729,125 - 64,729,185EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104654 AgrOrtholog
Ensembl Genes ENSMUSG00000073043 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000101351 ENTREZGENE
  ENSMUST00000101351.6 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot
InterPro ATOH1 UniProtKB/Swiss-Prot
  bHLH_dom UniProtKB/Swiss-Prot
  bHLH_transcription_factors UniProtKB/Swiss-Prot
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report mmu:11921 UniProtKB/Swiss-Prot
MGD MGI:104654 ENTREZGENE
NCBI Gene 11921 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED UniProtKB/Swiss-Prot
  PTHR19290:SF82 UniProtKB/Swiss-Prot
Pfam HLH UniProtKB/Swiss-Prot
PhenoGen Atoh1 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot
SMART HLH UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot
UniProt ATOH1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 Atoh1  atonal bHLH transcription factor 1    atonal homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED