Noto (notochord homeobox) - Rat Genome Database

Name: Noto
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Noto (notochord homeobox) Mus musculus

Analyze

Symbol:

Noto

Name:

notochord homeobox

RGD ID:

1557459

MGI Page

MGI

Description:

Is expressed in several structures, including embryo mesoderm; mesendoderm; primitive streak; and tail. Orthologous to human NOTO (notochord homeobox); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

Fl; Flh; floating head homolog; homeobox protein notochord; MmN; MmNot; N; Not; Not homeodomain protein; notochord homolog; tc; truncate

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NOTO (notochord homeobox)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Noto (notochord homeobox)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Noto (notochord homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NOTO (notochord homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NOTO (notochord homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Noto (notochord homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NOTO (notochord homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	NOTO (notochord homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Noto (notochord homeobox)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NOTO (notochord homeobox)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Rattus norvegicus (Norway rat):	Noto (notochord homeobox)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	noto (notochord homeobox)	Alliance	DIOPT (TreeFam\|ZFIN)
Drosophila melanogaster (fruit fly):	CG18599	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|Roundup)
Caenorhabditis elegans (roundworm):	ceh-23	Alliance	DIOPT (OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ceh-100	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	85,400,851 - 85,405,859 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	85,400,868 - 85,405,859 (+)	Ensembl
GRCm38	6	85,423,886 - 85,428,877 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	85,423,886 - 85,428,877 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	85,373,880 - 85,378,871 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	85,389,587 - 85,393,928 (+)	NCBI			mm8
Celera	6	87,395,820 - 87,400,823 (+)	NCBI		Celera
Cytogenetic Map	6	C3	NCBI
cM Map	6	37.44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3',4,4',5-Pentachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

folic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

central nervous system development (IBA)

determination of left/right symmetry (IMP)

dorsal/ventral pattern formation (IMP)

embryonic pattern specification (IMP)

heart looping (IMP)

motile cilium assembly (IGI)

multicellular organism development (IEA)

neuron differentiation (IBA)

notochord development (IMP)

regulation of cilium assembly (IMP)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IBA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific double-stranded DNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal blood vessel morphology (IAGP)

abnormal dorsal root ganglion morphology (IAGP)

abnormal embryonic cilium location or orientation (IAGP)

abnormal floor plate morphology (IAGP)

abnormal left-right axis patterning (IAGP)

abnormal motile primary cilium morphology (IAGP)

abnormal motile primary cilium physiology (IAGP)

abnormal primitive node morphology (IAGP)

abnormal sclerotome morphology (IAGP)

abnormal somite development (IAGP)

abnormal tail morphology (IAGP)

abnormal vertebrae morphology (IAGP)

absent nodal flow (IAGP)

absent tail (IAGP)

curly tail (IAGP)

decreased caudal vertebrae number (IAGP)

decreased embryonic cilium length (IAGP)

decreased lumbar vertebrae number (IAGP)

decreased vertebrae number (IAGP)

fusion of vertebral bodies (IAGP)

hindlimb paralysis (IAGP)

kinked tail (IAGP)

postnatal lethality (IAGP)

premature death (IAGP)

short tail (IAGP)

truncated notochord (IAGP)

References

References - curated


1.	MGD data from the GO Consortium
2.	MGD IEA
3.	RGD automated import pipeline
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8155581	PMID:9745042	PMID:10349636	PMID:10512192	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:13837681	PMID:15231714	PMID:15533813
PMID:15550757	PMID:16141072	PMID:16141073	PMID:17884984	PMID:17954925	PMID:18061569	PMID:19720144	PMID:20197654	PMID:20350929	PMID:21677750	PMID:21873635	PMID:22008794
PMID:22028328	PMID:22357932	PMID:23110100	PMID:23383217	PMID:23552073	PMID:23839921	PMID:24585447	PMID:25813538	PMID:27305836	PMID:27914912	PMID:28292423	PMID:28666954
PMID:28839193	PMID:29650695	PMID:30279523	PMID:31391582	PMID:32597756

Genomics

Comparative Map Data

Noto
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	85,400,851 - 85,405,859 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	85,400,868 - 85,405,859 (+)	Ensembl
GRCm38	6	85,423,886 - 85,428,877 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	85,423,886 - 85,428,877 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	85,373,880 - 85,378,871 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	85,389,587 - 85,393,928 (+)	NCBI			mm8
Celera	6	87,395,820 - 87,400,823 (+)	NCBI		Celera
Cytogenetic Map	6	C3	NCBI
cM Map	6	37.44	NCBI

NOTO
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	73,202,574 - 73,212,513 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	73,202,574 - 73,212,513 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	73,429,702 - 73,439,641 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	73,283,303 - 73,291,565 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	2	73,280,211 - 73,289,166 (+)	NCBI
Cytogenetic Map	2	p13.2	NCBI
HuRef	2	73,165,048 - 73,174,001 (+)	NCBI		HuRef
CHM1_1	2	73,360,196 - 73,369,145 (+)	NCBI		CHM1_1

Noto
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	117,961,163 - 117,965,402 (+)	NCBI
Rnor_6.0 Ensembl	4	117,206,355 - 117,210,856 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	4	117,206,355 - 117,210,856 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	181,783,984 - 181,788,485 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	119,677,428 - 119,681,667 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	4	106,943,268 - 106,947,507 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Noto
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955424	12,424,984 - 12,431,562 (-)	NCBI	ChiLan1.0	ChiLan1.0

NOTO
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	74,744,181 - 74,752,950 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	74,744,181 - 74,752,950 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	73,254,440 - 73,265,315 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

NOTO
(Canis lupus familiaris - dog)

No map positions available.

Noto
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936491	16,987,797 - 16,996,423 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NOTO
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	69,552,731 - 69,571,128 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	69,566,112 - 69,571,165 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	72,771,108 - 72,774,415 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NOTO
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	33,962,173 - 33,975,040 (-)	NCBI

Noto
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624762	430,981 - 439,422 (-)	NCBI

Position Markers

AU022460

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	85,428,062 - 85,428,274	UniSTS	GRCm38
MGSCv37	6	85,378,056 - 85,378,268	UniSTS	GRCm37
Celera	6	87,400,008 - 87,400,220	UniSTS
Cytogenetic Map	6	C3	UniSTS
cM Map	6	35.5	UniSTS
Whitehead/MRC_RH	6	883.63	UniSTS

Noto

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	6	C3	UniSTS
cM Map	6	35.6	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	1	117500000	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139100000	Mouse
1300556	Cia6_m	collagen induced arthritis QTL 6 (mouse)			Not determined		6	4464884	87426034	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96656149	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96656149	Mouse
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96656149	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96656149	Mouse
1558984	Cplaq9_m	circadian period of locomotor activity 9 (mouse)			Not determined		6	38669625	92607450	Mouse
1300618	Pgia19_m	proteoglycan induced arthritis 19 (mouse)			Not determined		6	45314059	87426034	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45314059	128835032	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46935985	136423692	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48720000	125360000	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48720000	148450000	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48726556	125356785	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52161713	116155267	Mouse
4141028	Mclr_m	methylcholanthrene lymphoma resistance (mouse)			Not determined			54373427	88379171	Mouse
15039373	Adip28_m	adiposity 28 (mouse)					6	56308211	90308211	Mouse
15039375	Bw41_m	body weight QTL 41 (mouse)					6	56308211	90308211	Mouse
1558977	Skmw10_m	skeletal muscle weight 10 (mouse)			Not determined		6	58447583	92447710	Mouse
10043972	Obq28_m	obesity QTL 28 (mouse)			Not determined		6	58540433	92540433	Mouse
1301740	Bwq2_m	body weight QTL 2 (mouse)			Not determined		6	60057680	94057799	Mouse
1301369	Im4_m	immunoregulatory 4 (mouse)			Not determined		6	63484738	97484905	Mouse
1300650	Bw18_m	body weight QTL 18 (mouse)			Not determined		6	66713869	100714031	Mouse
1301876	Bits2_m	bitterness sensitivity 2 (mouse)			Not determined		6	70425898	104426034	Mouse
1301813	Skl3_m	skeletal size (tail length) 3 (mouse)			Not determined		6	70425898	104426034	Mouse
1301034	Egrm2_m	early growth rate (mouse)			Not determined		6	70425898	104426034	Mouse
4141990	Etax6_m	ethanol induced ataxia 6 (mouse)			Not determined			71322621	86275719	Mouse
1302020	Bbaa20_m	B.burgdorferi-associated arthritis 20 (mouse)			Not determined		6	71322621	93464093	Mouse
1300869	Stheal5_m	soft tissue heal 5 (mouse)			Not determined		6	71575060	105575178	Mouse
1300954	Fcsa1_m	femoral cross-sectional area 1 (mouse)			Not determined		6	71981024	105981170	Mouse
1301521	Pas1c_m	pulmonary adenoma susceptibility 1c (mouse)			Not determined		6	71981024	105981170	Mouse
13506930	Recrq9_m	recombination rate in male meiosis QTL 9 (mouse)					6	73500000	134700000	Mouse
1301320	Ots1_m	ovarian teratoma susceptibility 1 (mouse)			Not determined		6	75447583	104503555	Mouse
1301571	Arrd1_m	age-related retinal degeneration 1 (mouse)			Not determined		6	75544356	92607450	Mouse
1300674	Nidd3n_m	non-insulin-dependent diabetes mellitus 3 in NSY (mouse)			Not determined		6	75544356	94225955	Mouse
10412195	Efw_m	epididymal fat weight (mouse)			Not determined		6	75544356	94225955	Mouse
10043901	Pfat5_m	predicted fat percentage 5 (mouse)			Not determined		6	75607306	109607450	Mouse
10412208	Cypr4_m	cytokine production 4 (mouse)			Not determined		6	75716503	109716697	Mouse
1357875	Pfat2_m	predicted fat percentage 2 (mouse)			Not determined		6	76463949	110464093	Mouse
14697704	Stsl4_m	Salmonella typhimurium susceptibility locus 4 (mouse)					6	77100000	90000000	Mouse
13824985	Alh1_m	amplitude of lateral head displacement 1 (mouse)					6	78000000	97000000	Mouse
4141376	Dbm1_m	diabetes modifier 1 (mouse)			Not determined		6	78629504	121115387	Mouse
14696731	Pairq1_m	P. aeruginosa infection resistance QTL 1 (mouse)					6	81500000	102200000	Mouse
10043864	T2dm4sa_m	type 2 diabetes mellitus 4 in SMXA RI mice (mouse)			Not determined		6	83713869	147052561	Mouse
11251720	Ewc4_m	ethanol withdrawal and consumption 4 (mouse)					6	84122513	118122513	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	503
Count of miRNA genes:	289
Interacting mature miRNAs:	390
Transcripts:	ENSMUST00000089578, ENSMUST00000174469
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006506356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC155728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ862873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ862874	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ862875	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK135886	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC139154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC139155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR354750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000089578 ⟹ ENSMUSP00000087006

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	85,423,886 - 85,428,877 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000174469 ⟹ ENSMUSP00000134424

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	85,424,068 - 85,428,277 (+)	Ensembl

RefSeq Acc Id:

NM_001007472 ⟹ NP_001007473

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	85,400,868 - 85,405,859 (+)	NCBI
GRCm38	6	85,423,886 - 85,428,877 (+)	ENTREZGENE
MGSCv37	6	85,373,880 - 85,378,871 (+)	RGD
Celera	6	87,395,820 - 87,400,823 (+)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

AGGGATCCTGATTCACAAGTCTCCCGTTCCTTTAGTAAGGTGACCACCTCTCTCTCTCCCATTG
AGCTCCTTGCACAGCCTGGGAGGTCCCCTCAGGGTCGCGCAATGTCCAGCCCTGCTCCCTCAGG
CACTCAGGTCCAGCCCGGGAGCCTGCGCCCCTGTCCGGGAGCTGTTTCCCCAGTTGTCCCGCGC
CGACTAGCTCGGGGACGCCTGGAGTCATCCTTCTCTGTCGAGGCCATCCTGGCGAGACCCAAGA
CCCGAGAGCTGGCGGCCACCTCTCTGCCGCTCTCTACCTGCACCAGTCTGAACCTCCTCGGTGC
GGTGTCGCAGTACGGGGTCCTGCCCTGGGTGTGCTCCACAGGGTCTTGGCTGCCTGCCTACCTG
AGCGTGGGCGTCTACCCGCTGTGCTCCATGTCCTGCGTGCCCGGACTGAATGTCACTCACCACC
AGCAGGGCCTCAGGCTCACAGGATCAGAGCTACCTTACTGTCTAGGCCCTCTGAAATGGGCACC
CACCGTGGACCTTCGGGACCACGGGACCGAGAGACACACAAAGAGGGTTCGCACAACGTTTAAC
TTGCAGCAGCTGCAAGAGTTGGAGAAGGTGTTTGCAAAGCAGCACAACCTGGTGGGGAAGGAGA
GAGCCCAGCTGGCTGCCAGGCTGCACCTGACGGAGAATCAGGTGAGGATCTGGTTCCAAAATCG
CAGGGTGAAGTATCAGAAGCAGCAAAAACTGAAATTGCCTTCCTCCTCTGTCATGGAGGAGCCC
TCCAGCAGCTCAGATGGCAACATCCAGAGTGAAGATGCTGAGTTGGGAATTGGCAGTTAAGGAC
CGAGCAAGAGGCTTTAGTTATATGGGCTAGTTCTTCCTGTGGTACCTGCTGGCCCTCCCTGTCC
CACATCTCAGTGAAGAGCTTCCTTAAGGTCAAAGGACACCAAATGTACTTGGACAATCAAGCAA
GGGAACTCTGGAAGCAGCATAATGGATTGACCTATGTCCTTGGCCAGGTTTTATGTCTTGCGGA
TAGAGGTATATTGATAACTTACACATCTCTCCCAGGGTGAGTTAAGGTCTGTAAAGCACTTACA
GAGTACCAGCTGGTGAGGTTTATGGGATAGACGCTGTCCCAGCTCTGCCCTGAAGATGGATTCA
TCAGCTCTCTCCTGGCCTGGCTATGGAGAATAGGCAGCCTTGAATCAGCATCACAGTGTGGAAA
GACTCTCCCCAAAGTCTAGAGAGAAGGAGATTTCTTAGCTCGCTTCAAACAAAGTTTCCTGCAT
TTCAACCCTATTTCTTTTCCTCTTGTCACCCTCCTCTGTATCTGGGGATGACTTTGGATTCCTG
ACCCTCTACTTCCCACGTGCTGGGATTACAGCTGCTTTTTTTTTTTTTTTTTTTGGAGGGGTGG
GGAGATTACAGATTCTCATTATGTGGCACAGATTGGCTTCAAATGCATGGAAATTCTCCTGTTT
TAACCTCTCTAGTGTTGAGGTAATGGGTAAAAGCCTCCATGCTTTGCCCAAAGTTTTCTTGTCT
GAGACTACTTTCAATAGGAGTCCATGTCATAGTGAGCTCAGGTTTATGGTAACTGGTTCCTTGG
AA

hide sequence

RefSeq Acc Id:

XM_006506356 ⟹ XP_006506419

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	85,400,851 - 85,405,255 (+)	NCBI
GRCm38	6	85,423,899 - 85,428,273 (+)	NCBI

Sequence:

show sequence

CACAAGTCTCCCGTTCCTTTAGTAAGGTGACCACCTCTCTCTCTCCCATTGAGCTCCTTGCACA
GCCTGGGAGGTCCCCTCAGGGTCGCGCAATGTCCAGCCCTGCTCCCTCAGGCACTCAGGTCCAG
CCCGGGAGCCTGCGCCCCTGTCCGGGAGCTGTTTCCCCAGTTGTCCCGCGCCGACTAGCTCGGG
GACGCCTGGAGTCATCCTTCTCTGTCGAGGCCATCCTGGCGAGACCCAAGACCCGAGAGCTGGC
GGCCACCTCTCTGCCGCTCTCTACCTGCACCAGTCTGAACCTCCTCGGTGCGGTGTCGCAGTAC
GGGGTCCTGCCCTGGGTGTGCTCCACAGGGTCTTGGCTGCCTGCCTACCTGAGCGTGGGCGTCT
ACCCGCTGTGCTCCATGTCCTGCGTGCCCGGACTGAATGTCACTCACCACCAGCAGGGCCTCAG
GCTCACAGGTGAGGATCTGGTTCCAAAATCGCAGGGTGAAGTATCAGAAGCAGCAAAAACTGAA
ATTGCCTTCCTCCTCTGTCATGGAGGAGCCCTCCAGCAGCTCAGATGGCAACATCCAGAGTGAA
GATGCTGAGTTGGGAATTGGCAGTTAAGGACCGAGCAAGAGGCTTTAGTTATATGGGCTAGTTC
TTCCTGTGGTACCTGCTGGCCCTCCCTGTCCCACATCTCAGTGAAGAGCTTCCTTAAGGTCAAA
GGACACCAAATGTACTTGGACAATCAAGCAAGGGAACTCTGGAAGCAGCATAATGGATTGACCT
ATGTC

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Protein Sequences


Protein RefSeqs	NP_001007473	(Get FASTA)	NCBI Sequence Viewer
	XP_006506419	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI39155	(Get FASTA)	NCBI Sequence Viewer
	AAI39156	(Get FASTA)	NCBI Sequence Viewer
	BAE22716	(Get FASTA)	NCBI Sequence Viewer
	CAI05851	(Get FASTA)	NCBI Sequence Viewer
	CAI05852	(Get FASTA)	NCBI Sequence Viewer
	CAI05853	(Get FASTA)	NCBI Sequence Viewer
	Q5TIS6	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001007473 ⟸ NM_001007472

- UniProtKB:

Q5TIS6 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSSPAPSGTQVQPGSLRPCPGAVSPVVPRRLARGRLESSFSVEAILARPKTRELAATSLPLSTC
TSLNLLGAVSQYGVLPWVCSTGSWLPAYLSVGVYPLCSMSCVPGLNVTHHQQGLRLTGSELPYC
LGPLKWAPTVDLRDHGTERHTKRVRTTFNLQQLQELEKVFAKQHNLVGKERAQLAARLHLTENQ
VRIWFQNRRVKYQKQQKLKLPSSSVMEEPSSSSDGNIQSEDAELGIGS

hide sequence

RefSeq Acc Id:	XP_006506419 ⟸ XM_006506356
- Peptide Label:	isoform X1
- Sequence:	show sequence MSSPAPSGTQVQPGSLRPCPGAVSPVVPRRLARGRLESSFSVEAILARPKTRELAATSLPLSTC TSLNLLGAVSQYGVLPWVCSTGSWLPAYLSVGVYPLCSMSCVPGLNVTHHQQGLRLTGEDLVPK SQGEVSEAAKTEIAFLLCHGGALQQLRWQHPE hide sequence

RefSeq Acc Id:

ENSMUSP00000134424 ⟸ ENSMUST00000174469

RefSeq Acc Id:

ENSMUSP00000087006 ⟸ ENSMUST00000089578

Promoters

RGD ID:

6839694

Promoter ID:

MM_KWN:46680

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Spleen

Transcripts:

ENSMUST00000089578

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	85,373,236 - 85,373,736 (+)	MPROMDB

RGD ID:

6890222

Promoter ID:

EPDNEW_M8562

Type:

single initiation site

Name:

Noto_1

Description:

Mus musculus notochord homeobox , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	85,423,886 - 85,423,946	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3053002	AgrOrtholog
Ensembl Genes	ENSMUSG00000068302	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000087006	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000134424	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000089578	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000174469	UniProtKB/TrEMBL
InterPro	Homeobox-like_sf	UniProtKB/Swiss-Prot
	Homeobox_dom	UniProtKB/Swiss-Prot
KEGG Report	mmu:384452	UniProtKB/Swiss-Prot
MGD	MGI:3053002	ENTREZGENE
NCBI Gene	384452	ENTREZGENE
Pfam	Homeodomain	UniProtKB/Swiss-Prot
PhenoGen	Noto	PhenoGen
PROSITE	HOMEOBOX_2	UniProtKB/Swiss-Prot
SMART	HOX	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46689	UniProtKB/Swiss-Prot
UniProt	G3UZB3_MOUSE	UniProtKB/TrEMBL
	NOTO_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-29	Noto	notochord homeobox		notochord homolog (Xenopus laevis)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)