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Gene: Noto (notochord homeobox) Rattus norvegicus
Symbol: Noto
Name: notochord homeobox
RGD ID: 1562910
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic organ development; motile cilium assembly; and nervous system development. Predicted to localize to nucleus. Orthologous to human NOTO (notochord homeobox); INTERACTS WITH bisphenol A; 2,3',4,4',5-Pentachlorobiphenyl (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Also known as: homeobox protein notochord; LOC502857; notochord homolog; notochord homolog (Xenopus laevis); RGD1562910; similar to Not homeodomain protein
Homo sapiens (human) : NOTO (notochord homeobox)  HGNC  Alliance
Mus musculus (house mouse) : Noto (notochord homeobox)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Noto (notochord homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : NOTO (notochord homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Noto (notochord homeobox)
Sus scrofa (pig) : NOTO (notochord homeobox)
Chlorocebus sabaeus (African green monkey) : NOTO (notochord homeobox)
Heterocephalus glaber (naked mole-rat) : Noto (notochord homeobox)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04117,206,355 - 117,210,856 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,206,355 - 117,210,856 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04181,783,984 - 181,788,485 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,677,428 - 119,681,667 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4106,943,268 - 106,947,507 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Noto
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562910
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.