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Gene: Il22 (interleukin 22) Mus musculus
Symbol: Il22
Name: interleukin 22
RGD ID: 1556865
Description: Predicted to have cytokine activity. Involved in several processes, including negative regulation of inflammatory response; positive regulation of transcription by RNA polymerase II; and regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to extracellular space. Is expressed in retina and skin. Used to study liposarcoma. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL22 (interleukin 22); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Il; IL-; IL-10-related T-cell-derived-inducible factor; IL-22; IL-22a; IL-TIF alpha; Iltif; ILTIF alpha; ILTIFa; interleukin 10-related T cell-derived inducible factor; interleukin-22; interleukin-22a; MGC129416; MGC129417
Homo sapiens (human) : IL22 (interleukin 22)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il22 (interleukin 22)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il22 (interleukin 22)
Pan paniscus (bonobo/pygmy chimpanzee) : IL22 (interleukin 22)
Canis lupus familiaris (dog) : IL22 (interleukin 22)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il22 (interleukin 22)
Sus scrofa (pig) : IL22 (interleukin 22)
Chlorocebus sabaeus (African green monkey) : IL22 (interleukin 22)
Heterocephalus glaber (naked mole-rat) : Il22 (interleukin 22)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3910118,040,456 - 118,045,952 (+)NCBI
GRCm3810118,204,584 - 118,210,047 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10118,204,942 - 118,210,047 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710117,642,020 - 117,647,103 (+)NCBIGRCm37mm9NCBIm37
Celera10120,158,587 - 120,163,674 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1066.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il22
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1556865
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.