Zbtb26 (zinc finger and BTB domain containing 26) - Rat Genome Database

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Gene: Zbtb26 (zinc finger and BTB domain containing 26) Mus musculus
Analyze
Symbol: Zbtb26
Name: zinc finger and BTB domain containing 26
RGD ID: 1552993
MGI Page MGI
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Is expressed in placenta. Orthologous to human ZBTB26 (zinc finger and BTB domain containing 26).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A630026F21Rik; MGC130360; MGC130361; zinc finger and BTB domain-containing protein 26; zinc finger protein 483
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39237,322,180 - 37,333,184 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl237,322,180 - 37,333,147 (-)EnsemblGRCm39 Ensembl
GRCm38237,432,168 - 37,443,172 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl237,432,168 - 37,443,135 (-)EnsemblGRCm38mm10GRCm38
MGSCv37237,287,688 - 37,298,641 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36237,254,177 - 37,265,130 (-)NCBIMGSCv36mm8
Celera237,116,176 - 37,127,129 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IBA)

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14681479   PMID:15368895   PMID:15618518   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635  
PMID:34351428   PMID:36831280  


Genomics

Comparative Map Data
Zbtb26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39237,322,180 - 37,333,184 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl237,322,180 - 37,333,147 (-)EnsemblGRCm39 Ensembl
GRCm38237,432,168 - 37,443,172 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl237,432,168 - 37,443,135 (-)EnsemblGRCm38mm10GRCm38
MGSCv37237,287,688 - 37,298,641 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36237,254,177 - 37,265,130 (-)NCBIMGSCv36mm8
Celera237,116,176 - 37,127,129 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.19NCBI
ZBTB26
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389122,915,566 - 122,931,512 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9122,915,566 - 122,931,512 (-)EnsemblGRCh38hg38GRCh38
GRCh379125,677,845 - 125,693,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369124,720,199 - 124,733,600 (-)NCBINCBI36Build 36hg18NCBI36
Build 349122,759,932 - 122,773,333NCBI
Celera996,328,698 - 96,342,098 (-)NCBICelera
Cytogenetic Map9q33.2NCBI
HuRef995,295,217 - 95,308,624 (-)NCBIHuRef
CHM1_19125,828,897 - 125,842,302 (-)NCBICHM1_1
T2T-CHM13v2.09135,112,805 - 135,128,757 (-)NCBIT2T-CHM13v2.0
Zbtb26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8341,605,097 - 41,617,706 (-)NCBIGRCr8
mRatBN7.2321,195,319 - 21,207,925 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl321,195,319 - 21,207,942 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx324,666,284 - 24,676,298 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0333,251,248 - 33,261,262 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0331,061,989 - 31,072,003 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0321,685,339 - 21,697,945 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl321,687,933 - 21,697,945 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0326,924,514 - 26,937,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4317,194,711 - 17,204,723 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1317,091,189 - 17,110,137 (-)NCBI
Celera319,633,479 - 19,643,491 (-)NCBICelera
Cytogenetic Map3q11NCBI
Zbtb26
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554195,031,534 - 5,044,983 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554195,031,500 - 5,044,983 (+)NCBIChiLan1.0ChiLan1.0
ZBTB26
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21116,419,655 - 16,435,791 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1916,422,003 - 16,438,148 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0994,040,784 - 94,056,791 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19122,374,407 - 122,390,385 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9122,377,452 - 122,378,777 (-)Ensemblpanpan1.1panPan2
ZBTB26
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1959,860,499 - 59,874,096 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha959,055,608 - 59,069,232 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0960,779,792 - 60,793,395 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1959,538,565 - 59,552,181 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0959,853,571 - 59,867,181 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0959,946,319 - 59,959,937 (+)NCBIUU_Cfam_GSD_1.0
Zbtb26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947191,632,030 - 191,645,812 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648711,403,129 - 11,414,330 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648711,403,129 - 11,414,331 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZBTB26
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1263,831,228 - 263,846,907 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11263,831,224 - 263,847,206 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21297,296,091 - 297,311,718 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZBTB26
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11215,203,525 - 15,216,682 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1215,214,777 - 15,216,102 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666079852,058 - 865,306 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zbtb26
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476012,004,136 - 12,017,064 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476012,004,242 - 12,018,361 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1301
Count of miRNA genes:557
Interacting mature miRNAs:686
Transcripts:ENSMUST00000067043, ENSMUST00000102789
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3579732469797406Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23599167971609412Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3579732469797406Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
13464253Ifvrq1_minfluenza virus resistance QTL 1 (mouse)23303449252034492Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3579732469797406Mouse

Markers in Region
BE099743  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38237,432,249 - 37,432,396UniSTSGRCm38
MGSCv37237,287,769 - 37,287,916UniSTSGRCm37
Celera237,116,257 - 37,116,404UniSTS
Cytogenetic Map2BUniSTS
Zbtb26  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
cM Map224.19UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000067043   ⟹   ENSMUSP00000070071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl237,322,180 - 37,333,133 (-)Ensembl
GRCm38.p6 Ensembl237,432,168 - 37,443,121 (-)Ensembl
Ensembl Acc Id: ENSMUST00000102789   ⟹   ENSMUSP00000099850
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl237,325,030 - 37,333,132 (-)Ensembl
GRCm38.p6 Ensembl237,435,018 - 37,443,120 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203522
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl237,328,491 - 37,333,147 (-)Ensembl
GRCm38.p6 Ensembl237,438,479 - 37,443,135 (-)Ensembl
RefSeq Acc Id: NM_199025   ⟹   NP_950190
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39237,322,180 - 37,333,184 (-)NCBI
GRCm38237,432,168 - 37,443,172 (-)NCBI
MGSCv37237,287,688 - 37,298,641 (-)RGD
Celera237,116,176 - 37,127,129 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_950190   ⟸   NM_199025
- UniProtKB: Q6P9Q3 (UniProtKB/TrEMBL),   Q8C8S0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000070071   ⟸   ENSMUST00000067043
Ensembl Acc Id: ENSMUSP00000099850   ⟸   ENSMUST00000102789
Protein Domains
BTB   C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C8S0-F1-model_v2 AlphaFold Q8C8S0 1-451 view protein structure

Promoters
RGD ID:6833117
Promoter ID:MM_KWN:28983
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000112919,   ENSMUST00000112932,   NM_146121,   NM_199025,   OTTMUST00000030112,   UC008JMU.1,   UC008JMW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36237,298,141 - 37,298,952 (-)MPROMDB
RGD ID:6877180
Promoter ID:EPDNEW_M2041
Type:initiation region
Name:Zbtb26_1
Description:Mus musculus zinc finger and BTB domain containing 26 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38237,443,145 - 37,443,205EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444402 AgrOrtholog
Ensembl Genes ENSMUSG00000050714 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000067043 ENTREZGENE
  ENSMUST00000067043.5 UniProtKB/TrEMBL
  ENSMUST00000102789.3 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:320633 UniProtKB/TrEMBL
MGD MGI:2444402 ENTREZGENE
NCBI Gene 320633 ENTREZGENE
PANTHER ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 26 UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zbtb26 PhenoGen
PROSITE BTB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt Q3TM56_MOUSE UniProtKB/TrEMBL
  Q69ZG1_MOUSE UniProtKB/TrEMBL
  Q6P9Q3 ENTREZGENE, UniProtKB/TrEMBL
  Q8C8S0 ENTREZGENE, UniProtKB/TrEMBL