Tfap4 (transcription factor AP4) - Rat Genome Database

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Gene: Tfap4 (transcription factor AP4) Mus musculus
Analyze
Symbol: Tfap4
Name: transcription factor AP4
RGD ID: 1552940
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway and positive regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human TFAP4 (transcription factor AP-4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI642933; AP; AP-4; bHLHc4; bHLHc41; D930048N17Rik; Tcfa; Tcfap4; transcription factor AP-4; transcription factor AP-4 (activating enhancer-binding protein 4)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,362,525 - 4,378,625 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,362,525 - 4,377,718 (-)EnsemblGRCm39 Ensembl
GRCm38164,544,661 - 4,560,762 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,544,661 - 4,559,854 (-)EnsemblGRCm38mm10GRCm38
MGSCv37164,544,661 - 4,559,720 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,459,889 - 4,474,948 (-)NCBIMGSCv36mm8
Celera165,172,967 - 5,188,068 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein. Phan LK, etal., J Clin Invest 2002 Nov;110(10):1449-59.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2123466   PMID:2833704   PMID:8530024   PMID:9050988   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11171123   PMID:11217851   PMID:12477932   PMID:12520002   PMID:12904583  
PMID:14610273   PMID:14681479   PMID:15944155   PMID:16141072   PMID:16141073   PMID:16924111   PMID:17151600   PMID:18287559   PMID:18557763   PMID:18799693   PMID:20059953   PMID:20412781  
PMID:21122108   PMID:21677750   PMID:21873191   PMID:21873635   PMID:22988430   PMID:23949224   PMID:24194600   PMID:24952961   PMID:25029552   PMID:25182747   PMID:25261373   PMID:27566940  
PMID:30177706   PMID:32968282   PMID:34283887   PMID:35624466   PMID:36894688   PMID:37060810   PMID:38355793  


Genomics

Comparative Map Data
Tfap4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,362,525 - 4,378,625 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,362,525 - 4,377,718 (-)EnsemblGRCm39 Ensembl
GRCm38164,544,661 - 4,560,762 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,544,661 - 4,559,854 (-)EnsemblGRCm38mm10GRCm38
MGSCv37164,544,661 - 4,559,720 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,459,889 - 4,474,948 (-)NCBIMGSCv36mm8
Celera165,172,967 - 5,188,068 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.45NCBI
TFAP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38164,257,186 - 4,273,023 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl164,257,186 - 4,273,075 (-)EnsemblGRCh38hg38GRCh38
GRCh37164,307,187 - 4,323,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,247,188 - 4,263,002 (-)NCBINCBI36Build 36hg18NCBI36
Build 34164,247,188 - 4,262,999NCBI
Celera164,514,186 - 4,529,994 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef164,274,201 - 4,289,950 (-)NCBIHuRef
CHM1_1164,306,776 - 4,322,587 (-)NCBICHM1_1
T2T-CHM13v2.0164,284,515 - 4,300,348 (-)NCBIT2T-CHM13v2.0
Tfap4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81011,507,242 - 11,525,794 (+)NCBIGRCr8
mRatBN7.21011,001,338 - 11,019,386 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1011,002,911 - 11,019,386 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,711,539 - 15,727,556 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01015,200,351 - 15,216,367 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,869,709 - 10,885,786 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01011,204,616 - 11,222,975 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1011,206,226 - 11,223,370 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,968,255 - 9,986,048 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41011,144,057 - 11,159,763 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11011,144,056 - 11,159,763 (+)NCBI
Celera109,964,931 - 9,979,711 (+)NCBICelera
Cytogenetic Map10q12NCBI
Tfap4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544213,160,450 - 13,175,057 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544213,160,467 - 13,174,288 (+)NCBIChiLan1.0ChiLan1.0
TFAP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,780,566 - 4,830,819 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,564,889 - 8,615,240 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,176,129 - 3,226,404 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,348,066 - 4,394,809 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,348,929 - 4,368,525 (-)Ensemblpanpan1.1panPan2
TFAP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1637,075,462 - 37,111,039 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl637,097,786 - 37,111,072 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha638,403,673 - 38,439,255 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0637,279,975 - 37,315,672 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl637,302,967 - 37,315,669 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1637,073,932 - 37,109,475 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0636,967,095 - 37,002,646 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0637,368,408 - 37,404,234 (+)NCBIUU_Cfam_GSD_1.0
Tfap4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,486,934 - 106,527,375 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936694210,672 - 222,619 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936694210,863 - 222,531 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFAP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl338,050,308 - 38,060,817 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1338,043,735 - 38,060,820 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TFAP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.153,931,288 - 3,960,039 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl53,932,149 - 3,954,486 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606826,695,606 - 26,761,798 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfap4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248242,044,235 - 2,058,662 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248242,044,322 - 2,105,571 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tfap4
394 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:449
Count of miRNA genes:288
Interacting mature miRNAs:348
Transcripts:ENSMUST00000005862
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1302106Rapop1_mradiation-induced apoptosis 1 (mouse)Not determined16378077915731053Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse

Markers in Region
AI642933  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38164,544,894 - 4,545,020UniSTSGRCm38
MGSCv37164,544,894 - 4,545,020UniSTSGRCm37
Celera165,173,200 - 5,173,326UniSTS
Cytogenetic Map16A1UniSTS
cM Map162.5UniSTS
Whitehead/MRC_RH1617.76UniSTS
UniSTS:237415  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38164,544,718 - 4,544,933UniSTSGRCm38
MGSCv37164,544,718 - 4,544,933UniSTSGRCm37
Celera165,173,024 - 5,173,239UniSTS
Cytogenetic Map16A1UniSTS
cM Map162.5UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001419427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF161262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000005862   ⟹   ENSMUSP00000005862
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl164,362,525 - 4,377,718 (-)Ensembl
GRCm38.p6 Ensembl164,544,661 - 4,559,854 (-)Ensembl
Ensembl Acc Id: ENSMUST00000229956   ⟹   ENSMUSP00000155803
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl164,365,239 - 4,370,826 (-)Ensembl
GRCm38.p6 Ensembl164,547,375 - 4,552,962 (-)Ensembl
Ensembl Acc Id: ENSMUST00000230875   ⟹   ENSMUSP00000155303
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl164,365,162 - 4,376,647 (-)Ensembl
GRCm38.p6 Ensembl164,547,298 - 4,558,783 (-)Ensembl
RefSeq Acc Id: NM_001419427   ⟹   NP_001406356
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
RefSeq Acc Id: NM_001419428   ⟹   NP_001406357
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
RefSeq Acc Id: NM_001419429   ⟹   NP_001406358
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
RefSeq Acc Id: NM_001419430   ⟹   NP_001406359
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
RefSeq Acc Id: NM_001419431   ⟹   NP_001406360
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,376,499 (-)NCBI
RefSeq Acc Id: NM_001419432   ⟹   NP_001406361
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,376,499 (-)NCBI
RefSeq Acc Id: NM_001419433   ⟹   NP_001406362
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
RefSeq Acc Id: NM_001419434   ⟹   NP_001406363
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
RefSeq Acc Id: NM_001419435   ⟹   NP_001406364
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
RefSeq Acc Id: NM_031182   ⟹   NP_112459
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,527 - 4,377,648 (-)NCBI
GRCm38164,544,661 - 4,559,720 (-)NCBI
MGSCv37164,544,661 - 4,559,720 (-)RGD
Celera165,172,967 - 5,188,068 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006522763   ⟹   XP_006522826
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,525 - 4,371,685 (-)NCBI
GRCm38164,544,661 - 4,553,820 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006522765   ⟹   XP_006522828
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,525 - 4,375,821 (-)NCBI
GRCm38164,544,661 - 4,557,957 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006522766   ⟹   XP_006522829
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,525 - 4,378,625 (-)NCBI
GRCm38164,544,661 - 4,560,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246047   ⟹   XP_011244349
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,525 - 4,374,847 (-)NCBI
GRCm38164,544,661 - 4,556,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017317166   ⟹   XP_017172655
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,525 - 4,370,877 (-)NCBI
GRCm38164,544,661 - 4,553,016 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249340   ⟹   XP_030105200
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,362,525 - 4,374,847 (-)NCBI
GRCm38164,544,661 - 4,556,983 (-)NCBI
Sequence:
RefSeq Acc Id: NP_112459   ⟸   NM_031182
- Peptide Label: isoform 1
- UniProtKB: Q8BWA4 (UniProtKB/TrEMBL),   Q9JIZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522829   ⟸   XM_006522766
- Peptide Label: isoform X2
- UniProtKB: Q8BWA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522828   ⟸   XM_006522765
- Peptide Label: isoform X2
- UniProtKB: Q8BWA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522826   ⟸   XM_006522763
- Peptide Label: isoform X2
- UniProtKB: Q8BWA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244349   ⟸   XM_011246047
- Peptide Label: isoform X2
- UniProtKB: Q8BWA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172655   ⟸   XM_017317166
- Peptide Label: isoform X1
- UniProtKB: Q8BWA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030105200   ⟸   XM_030249340
- Peptide Label: isoform X2
- UniProtKB: Q8BWA4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000155303   ⟸   ENSMUST00000230875
Ensembl Acc Id: ENSMUSP00000005862   ⟸   ENSMUST00000005862
Ensembl Acc Id: ENSMUSP00000155803   ⟸   ENSMUST00000229956
RefSeq Acc Id: NP_001406363   ⟸   NM_001419434
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001406364   ⟸   NM_001419435
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001406358   ⟸   NM_001419429
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001406357   ⟸   NM_001419428
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001406356   ⟸   NM_001419427
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001406359   ⟸   NM_001419430
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001406362   ⟸   NM_001419433
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001406361   ⟸   NM_001419432
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001406360   ⟸   NM_001419431
- Peptide Label: isoform 6
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JIZ5-F1-model_v2 AlphaFold Q9JIZ5 1-338 view protein structure

Promoters
RGD ID:6847347
Promoter ID:MM_ACW:19641
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   Lung
Transcripts:TCFAP4.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36164,552,926 - 4,553,426 (-)MPROMDB
RGD ID:6847346
Promoter ID:MM_ACW:19643
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:TCFAP4.CSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36164,558,416 - 4,559,117 (-)MPROMDB
RGD ID:6827578
Promoter ID:MM_KWN:19968
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4
Transcripts:ENSMUST00000005862
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36164,559,466 - 4,560,652 (-)MPROMDB
RGD ID:8685326
Promoter ID:EPDNEW_M20694
Type:multiple initiation site
Name:Tfap4_1
Description:Mus musculus transcription factor AP4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38164,559,667 - 4,559,727EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103239 AgrOrtholog
Ensembl Genes ENSMUSG00000005718 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000005862 ENTREZGENE
  ENSMUST00000005862.9 UniProtKB/TrEMBL
  ENSMUST00000229956.2 UniProtKB/TrEMBL
  ENSMUST00000230875.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro HLH_DNA-bd UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  Max-like/E-box_TFs UniProtKB/TrEMBL
MGD MGI:103239 ENTREZGENE
NCBI Gene Tfap4 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR AP-4 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PhenoGen Tfap4 PhenoGen
PROSITE HLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP HLH_basic UniProtKB/TrEMBL
UniProt A0A2R8VI80_MOUSE UniProtKB/TrEMBL
  A0A2R8W6R9_MOUSE UniProtKB/TrEMBL
  Q8BWA4 ENTREZGENE, UniProtKB/TrEMBL
  Q9JIZ5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Tfap4  transcription factor AP4  Tcfap4  transcription factor AP4  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 Tcfap4  transcription factor AP4  Tfap4  transcription factor AP4  Symbol and/or name change 5135510 APPROVED
2024-08-21 Tfap4  transcription factor AP4  Tcfap4  transcription factor AP4  Symbol and/or name change 5135510 APPROVED
2024-08-21 Tcfap4  transcription factor AP4  Tfap4  transcription factor AP4  Symbol and/or name change 5135510 APPROVED
2011-10-25 Tfap4  transcription factor AP4  Tcfap4  transcription factor AP4  Symbol and/or name change 5135510 APPROVED