Wif1 (Wnt inhibitory factor 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Wif1 (Wnt inhibitory factor 1) Mus musculus
Analyze
Symbol: Wif1
Name: Wnt inhibitory factor 1
RGD ID: 1552191
MGI Page MGI
Description: Predicted to enable Wnt-protein binding activity; activin receptor binding activity; and nodal binding activity. Acts upstream of or within positive regulation of fat cell differentiation. Predicted to be active in cell surface and extracellular region. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and urinary bladder cancer. Orthologous to human WIF1 (WNT inhibitory factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW107799; WIF-; WIF-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910120,869,909 - 120,936,547 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10120,869,865 - 120,936,555 (+)EnsemblGRCm39 Ensembl
GRCm3810121,034,004 - 121,100,642 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,033,960 - 121,100,650 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710120,471,060 - 120,537,698 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610120,437,290 - 120,503,702 (+)NCBIMGSCv36mm8
Celera10123,398,945 - 123,465,434 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1068.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
amitrole  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (EXP)
cannabidiol  (EXP)
carbon nanotube  (EXP)
carnosic acid  (EXP)
celastrol  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
curcumin  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichloroacetic acid  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
entinostat  (ISO)
ethosuximide  (ISO)
etoposide  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
gentamycin  (ISO)
graphite  (ISO)
isotretinoin  (ISO)
manganese(II) chloride  (ISO)
methimazole  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N,N-diethyl-m-toluamide  (ISO)
nitrofen  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (EXP)
phenylephrine  (ISO)
progesterone  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sporidesmin A  (ISO)
sulfadimethoxine  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Ai L, etal., Carcinogenesis. 2006 Jul;27(7):1341-8. Epub 2006 Feb 25.
2. Dominant-stable beta-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model. Boerboom D, etal., Cancer Res. 2006 Feb 15;66(4):1964-73.
3. Wnt signalling and its impact on development and cancer. Klaus A and Birchmeier W, Nat Rev Cancer. 2008 May;8(5):387-98.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. A comparison of the performance of microsatellite and methylation urine analysis for predicting the recurrence of urothelial cell carcinoma, and definition of a set of markers by Bayesian network analysis. Roupret M, etal., BJU Int. 2008 Mar 4;.
11. Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma. Steg A, etal., J Mol Diagn. 2006 Feb;8(1):76-83.
12. Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA. Urakami S, etal., Clin Cancer Res. 2006 Dec 1;12(23):6989-97.
13. WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer. Wissmann C, etal., J Pathol 2003 Oct;201(2):204-12.
14. Target genes of the WNT/beta-catenin pathway in Wilms tumors. Zirn B, etal., Genes Chromosomes Cancer. 2006 Jun;45(6):565-74.
Additional References at PubMed
PMID:10201374   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12055200   PMID:12412008   PMID:12477932   PMID:14681479   PMID:15489334   PMID:15527894   PMID:15555925  
PMID:15782199   PMID:15880404   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17374359   PMID:17964517   PMID:18258849   PMID:18287559   PMID:18351662   PMID:18586116   PMID:19185060  
PMID:19234195   PMID:19243017   PMID:19254785   PMID:19307728   PMID:19515997   PMID:19755491   PMID:19906978   PMID:20308569   PMID:20436479   PMID:20510229   PMID:20562862   PMID:21041481  
PMID:21087601   PMID:21150899   PMID:21179454   PMID:21267068   PMID:21270055   PMID:21652676   PMID:21873635   PMID:22008794   PMID:22115758   PMID:22155508   PMID:22866057   PMID:23087175  
PMID:23153495   PMID:23213461   PMID:23250216   PMID:23349620   PMID:23364326   PMID:23376422   PMID:23784913   PMID:23921644   PMID:24136988   PMID:24362065   PMID:24418259   PMID:24632949  
PMID:24952961   PMID:25043184   PMID:25082703   PMID:25486432   PMID:25546423   PMID:25571841   PMID:25893927   PMID:25918249   PMID:26173833   PMID:26235626   PMID:26273529   PMID:26450967  
PMID:26621269   PMID:26628093   PMID:26859490   PMID:27765763   PMID:27918915   PMID:28069742   PMID:28400434   PMID:28558017   PMID:28705898   PMID:28774883   PMID:28797033   PMID:30153454  
PMID:30254141   PMID:30912746   PMID:30916783   PMID:30932813   PMID:31138536   PMID:31550482   PMID:31776260   PMID:31924792   PMID:31987884   PMID:32857879   PMID:33318148   PMID:34003106  
PMID:34108685   PMID:34671097   PMID:35080047   PMID:35103284   PMID:35332151   PMID:35333176   PMID:36435829   PMID:37061208   PMID:37318953   PMID:37321213   PMID:38448948  


Genomics

Comparative Map Data
Wif1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910120,869,909 - 120,936,547 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10120,869,865 - 120,936,555 (+)EnsemblGRCm39 Ensembl
GRCm3810121,034,004 - 121,100,642 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,033,960 - 121,100,650 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710120,471,060 - 120,537,698 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610120,437,290 - 120,503,702 (+)NCBIMGSCv36mm8
Celera10123,398,945 - 123,465,434 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1068.98NCBI
WIF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381265,050,626 - 65,121,305 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1265,050,626 - 65,121,305 (-)EnsemblGRCh38hg38GRCh38
GRCh371265,444,406 - 65,515,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361263,730,673 - 63,801,383 (-)NCBINCBI36Build 36hg18NCBI36
Build 341263,730,675 - 63,801,356NCBI
Celera1265,109,871 - 65,180,833 (-)NCBICelera
Cytogenetic Map12q14.3NCBI
HuRef1262,496,029 - 62,566,998 (-)NCBIHuRef
CHM1_11265,411,498 - 65,482,433 (-)NCBICHM1_1
T2T-CHM13v2.01265,029,618 - 65,100,339 (-)NCBIT2T-CHM13v2.0
Wif1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8758,433,326 - 58,503,853 (+)NCBIGRCr8
mRatBN7.2756,548,060 - 56,618,364 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl756,548,053 - 56,618,360 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx758,454,386 - 58,524,705 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0760,657,318 - 60,727,638 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0760,434,982 - 60,505,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0763,094,955 - 63,165,158 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl763,094,911 - 63,165,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0763,077,688 - 63,147,646 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,330,517 - 60,400,697 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1760,417,062 - 60,421,426 (+)NCBI
Celera753,295,112 - 53,365,064 (+)NCBICelera
Cytogenetic Map7q22NCBI
Wif1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545811,754,120 - 11,834,047 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545811,755,147 - 11,834,047 (-)NCBIChiLan1.0ChiLan1.0
WIF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21029,240,767 - 29,312,147 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11229,237,538 - 29,308,918 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01223,795,280 - 23,866,666 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11224,299,354 - 24,370,591 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1224,299,351 - 24,370,807 (+)Ensemblpanpan1.1panPan2
WIF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1107,659,277 - 7,726,175 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl107,659,491 - 7,726,859 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha107,593,387 - 7,659,761 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0107,769,159 - 7,835,321 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl107,769,166 - 7,835,635 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1107,633,347 - 7,712,128 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0107,887,278 - 7,953,914 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0108,017,421 - 8,084,263 (-)NCBIUU_Cfam_GSD_1.0
Wif1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494550,775,944 - 50,846,476 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365453,263,623 - 3,333,937 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365453,263,646 - 3,334,163 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WIF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl529,450,442 - 29,543,913 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1529,450,442 - 29,543,913 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2532,490,649 - 32,517,056 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WIF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11160,728,316 - 60,800,181 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1160,727,948 - 60,799,960 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037184,954,130 - 185,026,129 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wif1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248023,248,964 - 3,333,338 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248023,248,934 - 3,333,263 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wif1
2483 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:466
Count of miRNA genes:259
Interacting mature miRNAs:273
Transcripts:ENSMUST00000020439, ENSMUST00000145691, ENSMUST00000175867
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084079650122041528Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084079650122041528Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84079650122041528Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84079650122041528Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084079650122041528Mouse
1300908Insq4_minsulin QTL 4 (mouse)Not determined1086909085120909229Mouse
1301520Uvbi1_mUVB induced immunosuppression 1 (mouse)Not determined1086909085120909229Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088088254122088391Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined88836456122836456Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1089927651123927754Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090506901125575232Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
27226725Tibw1_mtibia width 1, proximal, 5 week (mouse)10102735861123235905Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108515907130530862Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108515907130530862Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108575094130530862Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108575094130530862Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108575094130530862Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108575094130530862Mouse
27226722Tibw7_mtibia width 7, proximal, 16 week (mouse)10108635861125435869Mouse
27095902Scvln11_msacral vertebrae length 2, 10 week (mouse)10110035861125435869Mouse
11353822Insq12_minsulin QTL 12 (mouse)10110453347125515907Mouse
11353823Homaq2_mhomeostatic model assessment QTL 2 (mouse)10110453347125515907Mouse
26884391Skwq11_mskull length QTL 11, 16 week (mouse)10113535905121635905Mouse
26884433Zlq2_mzygomatic length QTL 2, 5 week (mouse)10113535905125735869Mouse
26884383Bzwq3_mbi-zygomatic width QTL 3, 5 week (mouse)10114235905122735905Mouse
13506931Recrq11_mrecombination rate in male meiosis QTL 11 (mouse)10114335905123635905Mouse
26884377Skwq3_mskull length QTL 3, 5 week (mouse)10114635905122735905Mouse
1300796Lmr5_mleishmaniasis resistance 5 (mouse)Not determined10116220635122179828Mouse
27226742Metcl4_mmetatarsal-calcaneal length 4, 5 week (mouse)10118135905125435869Mouse
27226795Scvln17_msacral vertebrae length 2, 16 week (mouse)10118435905124835905Mouse
27226718Tibw3_mtibia width 3, proximal, 10 week (mouse)10118835905125435869Mouse
27095926Pglq4_mpelvic girdle length QTL 4, 5 week (mouse)10119035905124835905Mouse
26884443Sklq5_mskull length QTL 5, 5 week (mouse)10119035905124835905Mouse
27095906Scvln5_msacral vertebrae length 2, 5 week (mouse)10119035905124835905Mouse
27226736Metcl15_mmetatarsal-calcaneal length 15, 16 week (mouse)10119035905124835905Mouse
27226747Metcl10_mmetatarsal-calcaneal length 10, 10 week (mouse)10119035905124835905Mouse
27226784Tibl4_mtibia length 4, 5 week (mouse)10119035905125435869Mouse
27226791Feml8_mfemur length 8, 5 week (mouse)10119035905125735869Mouse
1301701Aggr1_maggression 1 (mouse)Not determined10119506908125575232Mouse
13801032Hwtf2_mheart weight by femur 2 (mouse)10119835905121835905Mouse
11353834Pcholq2_mplasma cholesterol QTL 2 (mouse)10120243727125515907Mouse
11353838Gluq3_mblood glucose QTL 3 (mouse)10120243727125515907Mouse

Markers in Region
Wif1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv3710120,471,489 - 120,472,107UniSTSGRCm37
Celera10123,399,374 - 123,399,971UniSTS
Cytogenetic Map10D2UniSTS
cM Map10 UniSTS
AW107799  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810121,100,263 - 121,100,385UniSTSGRCm38
MGSCv3710120,537,319 - 120,537,441UniSTSGRCm37
Celera10123,465,056 - 123,465,177UniSTS
Cytogenetic Map10D2UniSTS
Whitehead/MRC_RH101272.44UniSTS
Wif1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10D2UniSTS
Wif1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10D2UniSTS
Wif1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810121,034,433 - 121,035,051UniSTSGRCm38
MGSCv3710120,471,489 - 120,472,107UniSTSGRCm37
Celera10123,399,374 - 123,399,971UniSTS
Cytogenetic Map10D2UniSTS
cM Map10 UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000020439   ⟹   ENSMUSP00000020439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10120,869,865 - 120,936,555 (+)Ensembl
GRCm38.p6 Ensembl10121,033,960 - 121,100,650 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145691
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10120,919,660 - 120,936,542 (+)Ensembl
GRCm38.p6 Ensembl10121,083,755 - 121,100,637 (+)Ensembl
RefSeq Acc Id: ENSMUST00000175867   ⟹   ENSMUSP00000135486
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10120,869,929 - 120,936,550 (+)Ensembl
GRCm38.p6 Ensembl10121,034,024 - 121,100,645 (+)Ensembl
RefSeq Acc Id: NM_011915   ⟹   NP_036045
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910120,869,909 - 120,936,547 (+)NCBI
GRCm3810121,034,004 - 121,100,642 (+)NCBI
MGSCv3710120,471,060 - 120,537,698 (+)RGD
Celera10123,398,945 - 123,465,434 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_036045   ⟸   NM_011915
- Peptide Label: precursor
- UniProtKB: Q9WUA1 (UniProtKB/Swiss-Prot),   Q3TYU1 (UniProtKB/TrEMBL),   H3BKQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020439   ⟸   ENSMUST00000020439
RefSeq Acc Id: ENSMUSP00000135486   ⟸   ENSMUST00000175867
Protein Domains
EGF-like   WIF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WUA1-F1-model_v2 AlphaFold Q9WUA1 1-379 view protein structure

Promoters
RGD ID:6820099
Promoter ID:MM_KWN:5783
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000068607
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610120,470,956 - 120,471,456 (+)MPROMDB
RGD ID:8673388
Promoter ID:EPDNEW_M14725
Type:initiation region
Name:Wif1_1
Description:Mus musculus Wnt inhibitory factor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14726  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810121,034,004 - 121,034,064EPDNEW
RGD ID:8673390
Promoter ID:EPDNEW_M14726
Type:initiation region
Name:Wif1_2
Description:Mus musculus Wnt inhibitory factor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14725  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810121,034,189 - 121,034,249EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1344332 AgrOrtholog
Ensembl Genes ENSMUSG00000020218 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020439 ENTREZGENE
  ENSMUST00000020439.11 UniProtKB/Swiss-Prot
  ENSMUST00000175867.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EGF-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_extracell UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WIF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WIF_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Wnt-inh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:24117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1344332 ENTREZGENE
NCBI Gene 24117 ENTREZGENE
PANTHER 3-PHYTASE UniProtKB/TrEMBL
  EGF-LIKE-DOMAIN, MULTIPLE 7, 8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WNT INHIBITORY FACTOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DL-JAG_EGF-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WIF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB WIF1 RGD
PhenoGen Wif1 PhenoGen
PRINTS WIFPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WIF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WIF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt H3BKQ8 ENTREZGENE, UniProtKB/TrEMBL
  Q3TYU1 ENTREZGENE, UniProtKB/TrEMBL
  Q99KR2_MOUSE UniProtKB/TrEMBL
  Q9WUA1 ENTREZGENE, UniProtKB/Swiss-Prot