SLC33A1 (solute carrier family 33 member 1) - Rat Genome Database

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Gene: SLC33A1 (solute carrier family 33 member 1) Sus scrofa
Analyze
Symbol: SLC33A1
Name: solute carrier family 33 member 1
RGD ID: 14278145
Description: ENCODES a protein that exhibits acetyl-CoA transmembrane transporter activity (inferred); protein homodimerization activity (inferred); INVOLVED IN acetyl-CoA transmembrane transport (inferred); ASSOCIATED WITH cataract (ortholog); Congenital Cataracts, Hearing Loss, and Neurodegeneration (ortholog); Developmental Disabilities (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: acetyl-coenzyme A transporter 1; solute carrier family 33 (acetyl-CoA transporter), member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1395,658,530 - 95,724,156 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11395,690,453 - 95,724,239 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213103,717,661 - 103,747,366 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SLC33A1PigCongenital Cataracts, Hearing Loss, and Neurodegeneration  ISOSLC33A1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15902551 more ...
SLC33A1PigDevelopmental Disabilities  ISOSLC33A1 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:32581362
SLC33A1Piggenetic disease  ISOSLC33A1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
SLC33A1Pighereditary spastic paraplegia  ISOSLC33A1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegiaClinVarPMID:24215330 more ...
SLC33A1Pighereditary spastic paraplegia 10  ISOSLC33A1 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegia and autosomal dominantClinVar 
SLC33A1Pighereditary spastic paraplegia 42  ISOSLC33A1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 42ClinVarPMID:19061983 more ...
SLC33A1Pigparaplegia  ISOSLC33A1 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:22243965 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SLC33A1Pigcataract  ISOSLC33A1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22243965
SLC33A1PigHearing Loss  ISOSLC33A1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22243965
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SLC33A1PigCongenital Cataracts, Hearing Loss, and Neurodegeneration  ISOSLC33A1 (Homo sapiens)7240710 OMIM 
SLC33A1Pighereditary spastic paraplegia 42  ISOSLC33A1 (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SLC33A1Pigacetyl-CoA transmembrane transport involved_inIEAInterPro:IPR024371150520179 InterProGO_REF:0000002
SLC33A1Pigacetyl-CoA transmembrane transport involved_inIEAUniProtKB:O00400 and ensembl:ENSP00000496241150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SLC33A1Pigendoplasmic reticulum membrane located_inIEAUniProtKB:O00400 and ensembl:ENSP00000496241150520179 EnsemblGO_REF:0000107
SLC33A1Pigmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
SLC33A1Pigmembrane located_inIEAUniProtKB-SubCell:SL-0162150520179 UniProtGO_REF:0000044
SLC33A1Pigmembrane located_inIEAInterPro:IPR004752 and InterPro:IPR024371150520179 InterProGO_REF:0000002

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SLC33A1Pigacetyl-CoA transmembrane transporter activity enablesIEAUniProtKB:O00400 and ensembl:ENSP00000496241150520179 EnsemblGO_REF:0000107
SLC33A1Pigacetyl-CoA transmembrane transporter activity enablesIEAInterPro:IPR024371150520179 InterProGO_REF:0000002
SLC33A1Pigprotein binding enablesISOUniProtKB:P135699068941 PMID:35156780 and PMID:36012204IntActPMID:35156780 and PMID:36012204
SLC33A1Pigprotein homodimerization activity enablesIEAUniProtKB:O00400 and ensembl:ENSP00000496241150520179 EnsemblGO_REF:0000107

PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  



SLC33A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1395,658,530 - 95,724,156 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11395,690,453 - 95,724,239 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213103,717,661 - 103,747,366 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC33A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383155,821,024 - 155,854,427 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3155,821,024 - 155,854,456 (-)EnsemblGRCh38hg38GRCh38
GRCh373155,538,813 - 155,572,216 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363157,028,065 - 157,054,861 (-)NCBINCBI36Build 36hg18NCBI36
Build 343157,028,072 - 157,054,869NCBI
Celera3153,965,573 - 153,993,678 (-)NCBICelera
Cytogenetic Map3q25.31NCBI
HuRef3152,938,818 - 152,966,761 (-)NCBIHuRef
CHM1_13155,507,626 - 155,535,526 (-)NCBICHM1_1
T2T-CHM13v2.03158,595,660 - 158,629,057 (-)NCBIT2T-CHM13v2.0
Slc33a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39363,849,744 - 63,872,154 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl363,840,928 - 63,872,189 (-)EnsemblGRCm39 Ensembl
GRCm38363,942,323 - 63,964,733 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl363,933,507 - 63,964,768 (-)EnsemblGRCm38mm10GRCm38
MGSCv37363,746,258 - 63,768,655 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36364,030,265 - 64,052,662 (-)NCBIMGSCv36mm8
Celera363,614,271 - 63,636,637 (-)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.08NCBI
Slc33a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82150,565,327 - 150,587,700 (-)NCBIGRCr8
mRatBN7.22148,415,660 - 148,438,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2148,415,666 - 148,437,758 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2155,144,334 - 155,166,535 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02153,193,799 - 153,215,999 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02147,826,472 - 147,848,673 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02154,520,170 - 154,542,981 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2154,520,087 - 154,542,919 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02173,904,052 - 173,926,434 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42153,768,885 - 153,791,102 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12153,718,848 - 153,741,065 (-)NCBI
Celera2142,691,385 - 142,713,443 (-)NCBICelera
Cytogenetic Map2q31NCBI
Slc33a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554486,885,153 - 6,905,631 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554486,885,153 - 6,905,641 (-)NCBIChiLan1.0ChiLan1.0
SLC33A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22153,741,581 - 153,769,681 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13153,746,314 - 153,774,411 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03152,882,563 - 152,910,434 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13160,933,257 - 160,961,723 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,933,258 - 160,961,723 (-)Ensemblpanpan1.1panPan2
SLC33A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12349,522,325 - 49,548,004 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2349,523,852 - 49,547,904 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2349,398,410 - 49,424,322 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02350,157,394 - 50,182,415 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2350,154,335 - 50,182,497 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12349,742,667 - 49,767,691 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02349,791,848 - 49,816,795 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02350,077,444 - 50,104,253 (-)NCBIUU_Cfam_GSD_1.0
Slc33a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560286,672,733 - 86,694,733 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365193,036,106 - 3,061,271 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365193,038,895 - 3,061,215 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC33A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11534,907,146 - 34,932,928 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1534,907,091 - 34,931,262 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660417,541,900 - 7,567,809 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc33a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473033,420,389 - 33,443,144 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473033,424,654 - 33,443,249 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in SLC33A1
679 total Variants



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3



Ensembl Acc Id: ENSSSCT00000027200   ⟹   ENSSSCP00000022310
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1395,693,057 - 95,724,156 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000028285   ⟹   ENSSSCP00000022359
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1395,658,530 - 95,724,153 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000045637   ⟹   ENSSSCP00000059170
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1395,658,997 - 95,724,153 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000083252   ⟹   ENSSSCP00000064557
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1395,693,057 - 95,723,934 (-)Ensembl
RefSeq Acc Id: NM_001244245   ⟹   NP_001231174
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11395,696,483 - 95,724,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005669929   ⟹   XP_005669986
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11395,694,856 - 95,724,189 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068489   ⟹   XP_020924148
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11395,690,453 - 95,724,239 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020924148   ⟸   XM_021068489
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SNA5 (UniProtKB/TrEMBL),   I3LE25 (UniProtKB/TrEMBL),   A0A8D1V9Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005669986   ⟸   XM_005669929
- Peptide Label: isoform X1
- UniProtKB: I3LE25 (UniProtKB/TrEMBL),   A0A4X1SNA5 (UniProtKB/TrEMBL),   A0A8D1V9Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231174   ⟸   NM_001244245
- UniProtKB: I3LE25 (UniProtKB/TrEMBL),   A0A4X1SNA5 (UniProtKB/TrEMBL),   A0A8D1V9Y0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000064557   ⟸   ENSSSCT00000083252
Ensembl Acc Id: ENSSSCP00000059170   ⟸   ENSSSCT00000045637



1 to 40 of 86 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000025316 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015057142 UniProtKB/TrEMBL
  ENSSSCG00025067292 UniProtKB/TrEMBL
  ENSSSCG00030055950 UniProtKB/TrEMBL
  ENSSSCG00035031381 UniProtKB/TrEMBL
  ENSSSCG00040063503 UniProtKB/TrEMBL
  ENSSSCG00045010731 UniProtKB/TrEMBL
  ENSSSCG00050034861 UniProtKB/TrEMBL
  ENSSSCG00055023793 UniProtKB/TrEMBL
  ENSSSCG00060036135 UniProtKB/TrEMBL
  ENSSSCG00065076936 UniProtKB/TrEMBL
  ENSSSCG00070002301 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027200 ENTREZGENE
  ENSSSCT00000027200.3 UniProtKB/TrEMBL
  ENSSSCT00000028285.4 UniProtKB/TrEMBL
  ENSSSCT00000083252.2 UniProtKB/TrEMBL
  ENSSSCT00015076170.1 UniProtKB/TrEMBL
  ENSSSCT00015076648.1 UniProtKB/TrEMBL
  ENSSSCT00015076709.1 UniProtKB/TrEMBL
  ENSSSCT00015076860.1 UniProtKB/TrEMBL
  ENSSSCT00025092445.1 UniProtKB/TrEMBL
  ENSSSCT00025092559.1 UniProtKB/TrEMBL
  ENSSSCT00025092758.1 UniProtKB/TrEMBL
  ENSSSCT00025092859.1 UniProtKB/TrEMBL
  ENSSSCT00025092954.1 UniProtKB/TrEMBL
  ENSSSCT00030077978.1 UniProtKB/TrEMBL
  ENSSSCT00030077996.1 UniProtKB/TrEMBL
  ENSSSCT00030078048.1 UniProtKB/TrEMBL
  ENSSSCT00030078068.1 UniProtKB/TrEMBL
  ENSSSCT00035041532.1 UniProtKB/TrEMBL
  ENSSSCT00035041540.1 UniProtKB/TrEMBL
  ENSSSCT00040086692.1 UniProtKB/TrEMBL
  ENSSSCT00040086771.1 UniProtKB/TrEMBL
  ENSSSCT00040086999.1 UniProtKB/TrEMBL
  ENSSSCT00040087111.1 UniProtKB/TrEMBL
  ENSSSCT00045018233.1 UniProtKB/TrEMBL
  ENSSSCT00045018300.1 UniProtKB/TrEMBL
  ENSSSCT00045018329.1 UniProtKB/TrEMBL
  ENSSSCT00045018360.1 UniProtKB/TrEMBL
  ENSSSCT00050046878.1 UniProtKB/TrEMBL
1 to 40 of 86 rows