PNLIPRP1 (pancreatic lipase related protein 1) - Rat Genome Database

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Gene: PNLIPRP1 (pancreatic lipase related protein 1) Sus scrofa
Analyze
Symbol: PNLIPRP1
Name: pancreatic lipase related protein 1
RGD ID: 14223190
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); lipase activity (ortholog); INVOLVED IN pancreas development (ortholog); response to glucocorticoid (ortholog); response to peptide hormone (ortholog); ASSOCIATED WITH prostate cancer (ortholog); syndromic microphthalmia 11 (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: inactive pancreatic lipase-related protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14126,797,074 - 126,812,152 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114126,796,943 - 126,812,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214138,093,021 - 138,108,274 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PNLIPRP1Pigprostate cancer  ISOPNLIPRP1 (Homo sapiens)9068941 RGDPMID:11384102 and REF_RGD_ID:2302990
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PNLIPRP1Pigsyndromic microphthalmia 11  ISOPNLIPRP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Microphthalmia and syndromic 11ClinVarPMID:28492532


Biological Process
1 to 10 of 10 rows

  
1 to 10 of 10 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PNLIPRP1Pigextracellular region located_inIEAUniProtKB-SubCell:SL-0243150520179 UniProtGO_REF:0000044
PNLIPRP1Pigextracellular region located_inIEAUniProtKB-KW:KW-0964150520179 UniProtGO_REF:0000043
PNLIPRP1Pigextracellular space  ISOPnliprp1 (Rattus norvegicus)9068941 RGDPMID:8967484 and REF_RGD_ID:2303161
PNLIPRP1Pigextracellular space NOT|located_inISOPNLIPRP1 (Homo sapiens)9068941 PMID:19824014UniProtPMID:19824014

Molecular Function
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PNLIPRP1Pigcalcium ion binding enablesISOPNLIPRP1 (Canis lupus familiaris)9068941 PMID:9726421UniProtPMID:9726421
PNLIPRP1Pigcarboxylic ester hydrolase activity enablesIEAInterPro:IPR016272150520179 InterProGO_REF:0000002
PNLIPRP1Piglipase activity NOT|enablesISOPNLIPRP1 (Homo sapiens)9068941 PMID:19824014UniProtPMID:19824014
PNLIPRP1Piglipase activity enablesIEAInterPro:IPR000734 and InterPro:IPR013818150520179 InterProGO_REF:0000002
PNLIPRP1Piglipase activity NOT|enablesISOPNLIPRP1 (Canis lupus familiaris)9068941 PMID:9726421UniProtPMID:9726421
PNLIPRP1Piglipase activity  ISOPnliprp1 (Rattus norvegicus)9068941 RGDPMID:8203536 and REF_RGD_ID:728275
PNLIPRP1Piglipoprotein lipase activity enablesIBAMGI:96820 more ...150520179 GO_CentralGO_REF:0000033
PNLIPRP1Pigmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
PNLIPRP1Pigphospholipase A1 activity enablesIBAPANTHER:PTN000906454 more ...150520179 GO_CentralGO_REF:0000033
PNLIPRP1Pigprotein binding  ISOUniProtKB:P028669068941 RGDPMID:8203536 and REF_RGD_ID:728275
PNLIPRP1Pigprotein binding enablesISOUniProtKB:A8MZ59 more ...9068941 PMID:32296183IntActPMID:32296183
PNLIPRP1Pigtriacylglycerol lipase activity enablesIEAInterPro:IPR002331150520179 InterProGO_REF:0000002
PNLIPRP1Pigtriacylglycerol lipase activity enablesIEAEC:3.1.1.3150520179 UniProtGO_REF:0000003
PNLIPRP1Pigtriacylglycerol lipase activity enablesIEARHEA:12044150520179 RHEAGO_REF:0000116
1 to 14 of 14 rows

PMID:22301074   PMID:30032202  



PNLIPRP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14126,797,074 - 126,812,152 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114126,796,943 - 126,812,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214138,093,021 - 138,108,274 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PNLIPRP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810116,590,959 - 116,609,175 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10116,590,385 - 116,609,175 (+)EnsemblGRCh38hg38GRCh38
GRCh3710118,350,471 - 118,368,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610118,340,480 - 118,358,676 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410118,340,479 - 118,358,676NCBI
Celera10112,079,787 - 112,097,984 (+)NCBICelera
Cytogenetic Map10q25.3NCBI
HuRef10111,977,755 - 111,995,968 (+)NCBIHuRef
CHM1_110118,633,621 - 118,651,818 (+)NCBICHM1_1
T2T-CHM13v2.010117,485,016 - 117,503,281 (+)NCBIT2T-CHM13v2.0
Pnliprp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391958,717,319 - 58,732,601 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1958,717,319 - 58,732,601 (+)EnsemblGRCm39 Ensembl
GRCm381958,728,887 - 58,744,169 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1958,728,887 - 58,744,169 (+)EnsemblGRCm38mm10GRCm38
MGSCv371958,803,377 - 58,818,659 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361958,782,137 - 58,797,419 (+)NCBIMGSCv36mm8
Celera1960,925,754 - 60,941,038 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1954.49NCBI
Pnliprp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81267,854,027 - 267,869,654 (+)NCBIGRCr8
mRatBN7.21257,867,885 - 257,883,514 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1257,867,885 - 257,883,514 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1266,072,078 - 266,087,671 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01272,778,094 - 272,793,685 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01265,420,355 - 265,436,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01279,867,034 - 279,882,663 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1279,867,034 - 279,882,663 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01287,228,054 - 287,243,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41265,237,786 - 265,253,415 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11265,448,830 - 265,464,460 (+)NCBI
Celera1253,523,704 - 253,539,212 (+)NCBICelera
Cytogenetic Map1q55NCBI
Pnliprp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543121,391,166 - 21,406,617 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543121,391,166 - 21,406,617 (+)NCBIChiLan1.0ChiLan1.0
PNLIPRP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12827,167,754 - 27,183,104 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2827,139,230 - 27,212,178 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2827,318,314 - 27,333,662 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02827,704,442 - 27,719,793 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2827,675,917 - 27,749,003 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12827,258,945 - 27,274,286 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02827,278,370 - 27,293,714 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02827,467,324 - 27,482,673 (+)NCBIUU_Cfam_GSD_1.0
Pnliprp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721318,998,121 - 19,012,865 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364866,548,603 - 6,563,148 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364866,548,481 - 6,563,144 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNLIPRP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19109,397,970 - 109,417,422 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9109,399,227 - 109,417,351 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604870,633,565 - 70,671,594 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pnliprp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473729,967,294 - 29,982,737 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in PNLIPRP1
591 total Variants



mesoderm
1



Ensembl Acc Id: ENSSSCT00000011659   ⟹   ENSSSCP00000011357
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14126,797,074 - 126,812,152 (+)Ensembl
RefSeq Acc Id: NM_001142897   ⟹   NP_001136369
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114126,796,943 - 126,812,152 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001136369   ⟸   NM_001142897
- Peptide Label: precursor
- UniProtKB: B8XY18 (UniProtKB/TrEMBL),   A0A4X1SYK0 (UniProtKB/TrEMBL),   A0A8D1GDF2 (UniProtKB/TrEMBL),   A0A8D1SCC4 (UniProtKB/TrEMBL),   A0A8D1ZF96 (UniProtKB/TrEMBL),   A0A8D0X187 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000011357   ⟸   ENSSSCT00000011659
PLAT



1 to 40 of 57 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000010659 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015030038 UniProtKB/TrEMBL
  ENSSSCG00025061338 UniProtKB/TrEMBL
  ENSSSCG00030045485 UniProtKB/TrEMBL
  ENSSSCG00035066753 UniProtKB/TrEMBL
  ENSSSCG00040051977 UniProtKB/TrEMBL
  ENSSSCG00045002449 UniProtKB/TrEMBL
  ENSSSCG00050066249 UniProtKB/TrEMBL
  ENSSSCG00055019107 UniProtKB/TrEMBL
  ENSSSCG00060002775 UniProtKB/TrEMBL
  ENSSSCG00065057396 UniProtKB/TrEMBL
  ENSSSCG00070005338 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011659 ENTREZGENE
  ENSSSCT00000011659.4 UniProtKB/TrEMBL
  ENSSSCT00015040723.1 UniProtKB/TrEMBL
  ENSSSCT00025084027.1 UniProtKB/TrEMBL
  ENSSSCT00030063671.1 UniProtKB/TrEMBL
  ENSSSCT00035090184.1 UniProtKB/TrEMBL
  ENSSSCT00040070373.1 UniProtKB/TrEMBL
  ENSSSCT00045003874.1 UniProtKB/TrEMBL
  ENSSSCT00050090282.1 UniProtKB/TrEMBL
  ENSSSCT00055037719.1 UniProtKB/TrEMBL
  ENSSSCT00060003419.1 UniProtKB/TrEMBL
  ENSSSCT00065078602.1 UniProtKB/TrEMBL
  ENSSSCT00070010144.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
  PLAT/LH2 domain UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Lipase/vitellogenin UniProtKB/TrEMBL
  Lipase_LIPH UniProtKB/TrEMBL
  Lipase_N UniProtKB/TrEMBL
  Lipase_panc UniProtKB/TrEMBL
  PLAT/LH2_dom UniProtKB/TrEMBL
  PLAT/LH2_dom_sf UniProtKB/TrEMBL
  TAG_lipase UniProtKB/TrEMBL
KEGG Report ssc:100155399 UniProtKB/TrEMBL
NCBI Gene PNLIPRP1 ENTREZGENE
PANTHER INACTIVE PANCREATIC LIPASE-RELATED PROTEIN 1 UniProtKB/TrEMBL
  PTHR11610 UniProtKB/TrEMBL
Pfam Lipase UniProtKB/TrEMBL
1 to 40 of 57 rows