MORC2 (MORC family CW-type zinc finger 2) - Rat Genome Database

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Gene: MORC2 (MORC family CW-type zinc finger 2) Sus scrofa
Analyze
Symbol: MORC2
Name: MORC family CW-type zinc finger 2
RGD ID: 14119670
Description: ENCODES a protein that exhibits histone binding (ortholog); identical protein binding (ortholog); INVOLVED IN chromatin remodeling (inferred); DNA damage response (inferred); negative regulation of gene expression, epigenetic (inferred); ASSOCIATED WITH autosomal dominant distal hereditary motor neuronopathy (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease axonal type 2Z (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); heterochromatin (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MORC family CW-type zinc finger protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,755,267 - 47,799,628 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,755,264 - 47,800,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,866,492 - 50,911,012 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
heterochromatin  (IEA)
nuclear matrix  (IEA)
nucleoplasm  (IEA)
nucleus  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MORC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,755,267 - 47,799,628 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,755,264 - 47,800,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,866,492 - 50,911,012 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MORC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,925,130 - 30,968,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,925,130 - 30,968,774 (-)EnsemblGRCh38hg38GRCh38
GRCh372231,321,117 - 31,364,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,652,600 - 29,694,187 (-)NCBINCBI36Build 36hg18NCBI36
Build 342229,647,153 - 29,688,741NCBI
Celera2215,122,742 - 15,164,330 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,285,133 - 14,326,407 (-)NCBIHuRef
CHM1_12231,282,433 - 31,324,011 (-)NCBICHM1_1
T2T-CHM13v2.02231,388,696 - 31,432,332 (-)NCBIT2T-CHM13v2.0
Morc2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,599,132 - 3,640,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,599,191 - 3,640,477 (+)EnsemblGRCm39 Ensembl
GRCm38113,649,189 - 3,690,477 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,649,191 - 3,690,477 (+)EnsemblGRCm38mm10GRCm38
MGSCv37113,549,497 - 3,590,375 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,558,703 - 3,590,375 (+)NCBIMGSCv36mm8
Celera114,140,624 - 4,181,559 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.56NCBI
Morc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,752,444 - 82,794,980 (+)NCBIGRCr8
mRatBN7.21478,529,603 - 78,571,375 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,527,009 - 78,571,343 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,979,369 - 83,012,468 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,219,459 - 84,252,558 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,665,250 - 80,698,349 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,889,138 - 83,930,263 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,889,089 - 83,930,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01484,574,236 - 84,615,162 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,303,606 - 84,336,702 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,313,435 - 84,355,799 (+)NCBI
Celera1477,450,490 - 77,483,586 (+)NCBICelera
Cytogenetic Map14q21NCBI
Morc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,124,737 - 5,164,495 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554555,124,737 - 5,164,495 (-)NCBIChiLan1.0ChiLan1.0
MORC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22340,866,775 - 40,927,594 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,542,482 - 43,625,953 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02211,912,043 - 11,995,497 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,751,768 - 29,795,632 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,753,241 - 29,795,632 (-)Ensemblpanpan1.1panPan2
MORC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12623,951,704 - 23,993,620 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2623,953,130 - 23,992,431 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,822,612 - 23,864,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,334,724 - 24,376,359 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,334,732 - 24,376,451 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,037,763 - 24,079,863 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,299,937 - 24,341,812 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,361,090 - 24,402,720 (-)NCBIUU_Cfam_GSD_1.0
Morc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118116,875,801 - 116,913,536 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755130,983 - 171,492 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936755133,315 - 171,507 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MORC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,817,597 - 13,859,986 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1913,815,467 - 13,858,633 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045112,260,712 - 112,304,739 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Morc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,384,270 - 7,426,285 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,386,052 - 7,426,257 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MORC2
668 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 1 10 1 1
Low 10 4 4 2 13 1 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000010973   ⟹   ENSSSCP00000010687
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1447,755,267 - 47,799,619 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000061702   ⟹   ENSSSCP00000042480
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1447,756,761 - 47,799,426 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000061981   ⟹   ENSSSCP00000034563
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1447,756,760 - 47,799,628 (-)Ensembl
RefSeq Acc Id: XM_005670851   ⟹   XP_005670908
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,755,264 - 47,799,648 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005670852   ⟹   XP_005670909
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,756,749 - 47,799,625 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005670853   ⟹   XP_005670910
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,755,264 - 47,800,432 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005670854   ⟹   XP_005670911
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,755,264 - 47,799,625 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013983067   ⟹   XP_013838521
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,755,264 - 47,799,641 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013983068   ⟹   XP_013838522
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,755,264 - 47,799,625 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021072947   ⟹   XP_020928606
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,755,264 - 47,799,666 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021072948   ⟹   XP_020928607
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11447,755,264 - 47,799,700 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005670910   ⟸   XM_005670853
- Peptide Label: isoform X4
- UniProtKB: A0A4X1V6A2 (UniProtKB/TrEMBL),   F1RPD9 (UniProtKB/TrEMBL),   A0A8D0YLY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020928607   ⟸   XM_021072948
- Peptide Label: isoform X8
- UniProtKB: A0A8D0QDG9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020928606   ⟸   XM_021072947
- Peptide Label: isoform X7
- UniProtKB: A0A8D1Y8V5 (UniProtKB/TrEMBL),   A0A8D0YRX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005670908   ⟸   XM_005670851
- Peptide Label: isoform X2
- UniProtKB: A0A4X1VC54 (UniProtKB/TrEMBL),   A0A480TIM3 (UniProtKB/TrEMBL),   A0A8D0YLY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013838521   ⟸   XM_013983067
- Peptide Label: isoform X1
- UniProtKB: A0A8D0QFQ8 (UniProtKB/TrEMBL),   A0A8D0YLY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013838522   ⟸   XM_013983068
- Peptide Label: isoform X6
- UniProtKB: A0A8D0QDG9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005670911   ⟸   XM_005670854
- Peptide Label: isoform X5
- UniProtKB: A0A8D0YLY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005670909   ⟸   XM_005670852
- Peptide Label: isoform X3
- UniProtKB: A0A8D0YLY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010687   ⟸   ENSSSCT00000010973
RefSeq Acc Id: ENSSSCP00000042480   ⟸   ENSSSCT00000061702
RefSeq Acc Id: ENSSSCP00000034563   ⟸   ENSSSCT00000061981
Protein Domains
CW-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010016 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015081097 UniProtKB/TrEMBL
  ENSSSCG00025062928 UniProtKB/TrEMBL
  ENSSSCG00030027797 UniProtKB/TrEMBL
  ENSSSCG00035011002 UniProtKB/TrEMBL
  ENSSSCG00040005714 UniProtKB/TrEMBL
  ENSSSCG00045003273 UniProtKB/TrEMBL
  ENSSSCG00050077438 UniProtKB/TrEMBL
  ENSSSCG00055007016 UniProtKB/TrEMBL
  ENSSSCG00060072846 UniProtKB/TrEMBL
  ENSSSCG00065028271 UniProtKB/TrEMBL
  ENSSSCG00070022859 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010973 ENTREZGENE
  ENSSSCT00000010973.5 UniProtKB/TrEMBL
  ENSSSCT00000061702 ENTREZGENE
  ENSSSCT00000061702.2 UniProtKB/TrEMBL
  ENSSSCT00000061981.3 UniProtKB/TrEMBL
  ENSSSCT00015110552.1 UniProtKB/TrEMBL
  ENSSSCT00015110554.1 UniProtKB/TrEMBL
  ENSSSCT00015110556.1 UniProtKB/TrEMBL
  ENSSSCT00015110557.1 UniProtKB/TrEMBL
  ENSSSCT00025086165.1 UniProtKB/TrEMBL
  ENSSSCT00025086644.1 UniProtKB/TrEMBL
  ENSSSCT00025087100.1 UniProtKB/TrEMBL
  ENSSSCT00030038867.1 UniProtKB/TrEMBL
  ENSSSCT00030038875.1 UniProtKB/TrEMBL
  ENSSSCT00030038882.1 UniProtKB/TrEMBL
  ENSSSCT00035013788.1 UniProtKB/TrEMBL
  ENSSSCT00035013795.1 UniProtKB/TrEMBL
  ENSSSCT00040007548.1 UniProtKB/TrEMBL
  ENSSSCT00040007565.1 UniProtKB/TrEMBL
  ENSSSCT00040007589.1 UniProtKB/TrEMBL
  ENSSSCT00045005317.1 UniProtKB/TrEMBL
  ENSSSCT00045005327.1 UniProtKB/TrEMBL
  ENSSSCT00045005344.1 UniProtKB/TrEMBL
  ENSSSCT00050106566.1 UniProtKB/TrEMBL
  ENSSSCT00050106570.1 UniProtKB/TrEMBL
  ENSSSCT00050106585.1 UniProtKB/TrEMBL
  ENSSSCT00055013603.1 UniProtKB/TrEMBL
  ENSSSCT00055013679.1 UniProtKB/TrEMBL
  ENSSSCT00055013793.1 UniProtKB/TrEMBL
  ENSSSCT00060099536.1 UniProtKB/TrEMBL
  ENSSSCT00060099627.1 UniProtKB/TrEMBL
  ENSSSCT00060099792.1 UniProtKB/TrEMBL
  ENSSSCT00065038124.1 UniProtKB/TrEMBL
  ENSSSCT00065038130.1 UniProtKB/TrEMBL
  ENSSSCT00065038142.1 UniProtKB/TrEMBL
  ENSSSCT00070045495.1 UniProtKB/TrEMBL
  ENSSSCT00070045509.1 UniProtKB/TrEMBL
  ENSSSCT00070045524.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.100 UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/TrEMBL
InterPro HATPase_C_sf UniProtKB/TrEMBL
  Morc_S5 UniProtKB/TrEMBL
  Znf_CW UniProtKB/TrEMBL
KEGG Report ssc:100153895 UniProtKB/TrEMBL
NCBI Gene MORC2 ENTREZGENE
PANTHER ATPASE MORC2 UniProtKB/TrEMBL
  ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 UniProtKB/TrEMBL
Pfam HATPase_c_3 UniProtKB/TrEMBL
  Morc6_S5 UniProtKB/TrEMBL
  zf-CW UniProtKB/TrEMBL
PROSITE ZF_CW UniProtKB/TrEMBL
Superfamily-SCOP SSF55874 UniProtKB/TrEMBL
UniProt A0A286ZSV9_PIG UniProtKB/TrEMBL
  A0A287AF63_PIG UniProtKB/TrEMBL
  A0A480TIM3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V6A2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V9P3_PIG UniProtKB/TrEMBL
  A0A4X1VC54 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QDG9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QFQ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QLM9_PIG UniProtKB/TrEMBL
  A0A8D0YLY9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YRX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Y8V5 ENTREZGENE, UniProtKB/TrEMBL
  F1RPD9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90303 ENTREZGENE