Morc2 (MORC family CW-type zinc finger 2) - Rat Genome Database

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Gene: Morc2 (MORC family CW-type zinc finger 2) Heterocephalus glaber
Analyze
Symbol: Morc2
Name: MORC family CW-type zinc finger 2
RGD ID: 18907233
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); chromatin binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); DNA damage response (ortholog); negative regulation of gene expression, epigenetic (ortholog); ASSOCIATED WITH autosomal dominant distal hereditary motor neuronopathy (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease axonal type 2Z (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); heterochromatin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MORC family CW-type zinc finger protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,384,270 - 7,426,285 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,386,052 - 7,426,257 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Morc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,384,270 - 7,426,285 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,386,052 - 7,426,257 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MORC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,925,130 - 30,968,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,925,130 - 30,968,774 (-)EnsemblGRCh38hg38GRCh38
GRCh372231,321,117 - 31,364,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,652,600 - 29,694,187 (-)NCBINCBI36Build 36hg18NCBI36
Build 342229,647,153 - 29,688,741NCBI
Celera2215,122,742 - 15,164,330 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,285,133 - 14,326,407 (-)NCBIHuRef
CHM1_12231,282,433 - 31,324,011 (-)NCBICHM1_1
T2T-CHM13v2.02231,388,696 - 31,432,332 (-)NCBIT2T-CHM13v2.0
Morc2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,599,132 - 3,640,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,599,191 - 3,640,477 (+)EnsemblGRCm39 Ensembl
GRCm38113,649,189 - 3,690,477 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,649,191 - 3,690,477 (+)EnsemblGRCm38mm10GRCm38
MGSCv37113,549,497 - 3,590,375 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,558,703 - 3,590,375 (+)NCBIMGSCv36mm8
Celera114,140,624 - 4,181,559 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.56NCBI
Morc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,752,444 - 82,794,980 (+)NCBIGRCr8
mRatBN7.21478,529,603 - 78,571,375 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,527,009 - 78,571,343 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,979,369 - 83,012,468 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,219,459 - 84,252,558 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,665,250 - 80,698,349 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,889,138 - 83,930,263 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,889,089 - 83,930,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01484,574,236 - 84,615,162 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,303,606 - 84,336,702 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,313,435 - 84,355,799 (+)NCBI
Celera1477,450,490 - 77,483,586 (+)NCBICelera
Cytogenetic Map14q21NCBI
Morc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,124,737 - 5,164,495 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554555,124,737 - 5,164,495 (-)NCBIChiLan1.0ChiLan1.0
MORC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22340,866,775 - 40,927,594 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,542,482 - 43,625,953 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02211,912,043 - 11,995,497 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,751,768 - 29,795,632 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,753,241 - 29,795,632 (-)Ensemblpanpan1.1panPan2
MORC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12623,951,704 - 23,993,620 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2623,953,130 - 23,992,431 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,822,612 - 23,864,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,334,724 - 24,376,359 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,334,732 - 24,376,451 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,037,763 - 24,079,863 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,299,937 - 24,341,812 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,361,090 - 24,402,720 (-)NCBIUU_Cfam_GSD_1.0
Morc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118116,875,801 - 116,913,536 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755130,983 - 171,492 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936755133,315 - 171,507 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MORC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,755,267 - 47,799,628 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,755,264 - 47,800,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,866,492 - 50,911,012 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MORC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,817,597 - 13,859,986 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1913,815,467 - 13,858,633 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045112,260,712 - 112,304,739 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019895   ⟹   ENSHGLP00000019699
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247477,384,270 - 7,426,285 (-)Ensembl
RefSeq Acc Id: XM_004843464   ⟹   XP_004843521
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247477,386,052 - 7,426,257 (-)NCBI
RefSeq Acc Id: XM_013071668   ⟹   XP_012927122
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247477,386,052 - 7,426,257 (-)NCBI
RefSeq Acc Id: XM_013071669   ⟹   XP_012927123
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247477,386,052 - 7,426,257 (-)NCBI
RefSeq Acc Id: XM_013071670   ⟹   XP_012927124
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247477,386,052 - 7,426,257 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004843521 (Get FASTA)   NCBI Sequence Viewer  
  XP_012927122 (Get FASTA)   NCBI Sequence Viewer  
  XP_012927123 (Get FASTA)   NCBI Sequence Viewer  
  XP_012927124 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019699
  ENSHGLP00100048011
GenBank Protein JAN97494 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_012927124   ⟸   XM_013071670
- Peptide Label: isoform X4
- UniProtKB: G5BBU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012927123   ⟸   XM_013071669
- Peptide Label: isoform X2
- UniProtKB: G5BBU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004843521   ⟸   XM_004843464
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J4P3 (UniProtKB/TrEMBL),   G5BBU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012927122   ⟸   XM_013071668
- Peptide Label: isoform X1
- UniProtKB: G5BBU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019699   ⟸   ENSHGLT00000019895


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014099 Ensembl, ENTREZGENE
  ENSHGLG00100006413 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000019895 ENTREZGENE
  ENSHGLT00100058677 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.100 UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/TrEMBL
InterPro HATPase_C_sf UniProtKB/TrEMBL
  Morc_S5 UniProtKB/TrEMBL
  Znf_CW UniProtKB/TrEMBL
KEGG Report hgl:101724396 UniProtKB/TrEMBL
NCBI Gene Morc2 ENTREZGENE
PANTHER ATPASE MORC2 UniProtKB/TrEMBL
  ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1 UniProtKB/TrEMBL
Pfam HATPase_c_3 UniProtKB/TrEMBL
  Morc6_S5 UniProtKB/TrEMBL
  zf-CW UniProtKB/TrEMBL
PROSITE ZF_CW UniProtKB/TrEMBL
Superfamily-SCOP SSF55874 UniProtKB/TrEMBL
UniProt A0A0P6J4P3 ENTREZGENE, UniProtKB/TrEMBL
  G5BBU0 ENTREZGENE, UniProtKB/TrEMBL