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Gene: IQGAP2 (IQ motif containing GTPase activating protein 2) Sus scrofa

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Symbol:

IQGAP2

Name:

IQ motif containing GTPase activating protein 2

RGD ID:

14110570

Description:

ENCODES a protein that exhibits actin filament binding (inferred); Arp2/3 complex binding (inferred); calmodulin binding (inferred); INVOLVED IN Arp2/3 complex-mediated actin nucleation (inferred); regulation of actin cytoskeleton organization (inferred); thrombin-activated receptor signaling pathway (inferred); ASSOCIATED WITH Brain Neoplasms (ortholog); hepatocellular carcinoma (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN microtubule (ortholog); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras GTPase-activating-like protein IQGAP2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	85,294,530 - 85,633,642 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	85,294,423 - 85,633,645 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	86,916,946 - 87,086,957 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IQGAP2	Pig	Neurodevelopmental Disorders		ISO	IQGAP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IQGAP2	Pig	Brain Neoplasms		ISO	IQGAP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:27935819
IQGAP2	Pig	hepatocellular carcinoma		ISO	IQGAP2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20977743

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IQGAP2	Pig	hepatocellular carcinoma		ISO	Iqgap2 (Mus musculus)	9068941	OMIM:114550	MouseDO

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IQGAP2	Pig	deoxynivalenol	decreases expression	EXP		6480464	deoxynivalenol results in decreased expression of IQGAP2 mRNA	CTD	PMID:35307453

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IQGAP2	Pig	Arp2/3 complex-mediated actin nucleation	involved_in	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	mitotic actomyosin contractile ring assembly actin filament organization	involved_in	IBA	PANTHER:PTN000365541 and SGD:S000006163	150520179		GO_Central	GO_REF:0000033
IQGAP2	Pig	regulation of actin cytoskeleton organization	involved_in	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	thrombin-activated receptor signaling pathway	involved_in	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IQGAP2	Pig	cell cortex	is_active_in	IBA	CGD:CAL0000175167 more ...	150520179		GO_Central	GO_REF:0000033
IQGAP2	Pig	cell surface	located_in	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	cytoplasm	located_in	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	filopodium	located_in	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	lamellipodium	located_in	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	microtubule	located_in	ISO	IQGAP2 (Homo sapiens)	9068941	PMID:21525035	UniProt	PMID:21525035
IQGAP2	Pig	microvillus	located_in	IEA	UniProtKB:Q3UQ44 and ensembl:ENSMUSP00000067685	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	plasma membrane bounded cell projection	located_in	IEA	ARBA:ARBA00028036	150520179		UniProt	GO_REF:0000117

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
IQGAP2	Pig	actin filament binding	enables	IBA	PANTHER:PTN000365541 more ...	150520179		GO_Central	GO_REF:0000033
IQGAP2	Pig	actin filament binding	enables	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	Arp2/3 complex binding	enables	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	calmodulin binding	enables	IBA	PANTHER:PTN000365541 more ...	150520179		GO_Central	GO_REF:0000033
IQGAP2	Pig	calmodulin binding	enables	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	GTPase activator activity	enables	IBA	PANTHER:PTN000365540 more ...	150520179		GO_Central	GO_REF:0000033
IQGAP2	Pig	phosphatidylinositol-3,4,5-trisphosphate binding	enables	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107
IQGAP2	Pig	small GTPase binding	enables	IEA	UniProtKB:Q13576 and ensembl:ENSP00000274364	150520179		Ensembl	GO_REF:0000107

PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

IQGAP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	85,294,530 - 85,633,642 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	85,294,423 - 85,633,645 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	86,916,946 - 87,086,957 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IQGAP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	76,403,285 - 76,708,132 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	76,403,285 - 76,708,132 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	75,699,110 - 76,003,957 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	75,734,905 - 76,039,713 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	75,734,904 - 76,039,711	NCBI
Celera	5	71,592,826 - 71,897,903 (+)	NCBI		Celera
Cytogenetic Map	5	q13.3	NCBI
HuRef	5	70,906,692 - 71,211,466 (+)	NCBI		HuRef
CHM1_1	5	75,131,847 - 75,437,149 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	76,885,042 - 77,189,993 (+)	NCBI		T2T-CHM13v2.0

Iqgap2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	95,763,685 - 96,028,788 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	95,763,682 - 96,028,991 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	95,627,177 - 95,892,280 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	95,627,174 - 95,892,483 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	96,397,132 - 96,661,877 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	96,397,132 - 96,661,877 (-)	NCBI		MGSCv36	mm8
Celera	13	99,243,963 - 99,510,431 (-)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI
cM Map	13	50.26	NCBI

Iqgap2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	28,629,558 - 28,904,649 (-)	NCBI		GRCr8
mRatBN7.2	2	26,894,836 - 27,170,270 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	26,894,825 - 27,170,279 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	26,161,628 - 26,439,067 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	26,167,199 - 26,438,790 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	45,295,534 - 45,569,560 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	26,039,689 - 26,147,538 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	22,958,327 - 23,102,329 (-)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

Iqgap2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	24,167,104 - 24,385,146 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	24,167,985 - 24,384,912 (-)	NCBI	ChiLan1.0	ChiLan1.0

IQGAP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	38,597,137 - 38,902,374 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	36,750,767 - 37,056,000 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	38,593,574 - 38,900,327 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	39,137,539 - 39,516,894 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	39,138,359 - 39,516,596 (-)	Ensembl	panpan1.1		panPan2

IQGAP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	29,894,192 - 30,134,594 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	29,894,870 - 30,174,259 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	31,132,907 - 31,420,147 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	29,818,056 - 30,105,892 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	29,818,467 - 30,106,093 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	29,749,579 - 30,036,702 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	29,730,444 - 30,016,347 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	30,099,810 - 30,387,253 (-)	NCBI		UU_Cfam_GSD_1.0

Iqgap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	190,317,091 - 190,603,571 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936549	255,303 - 541,917 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936549	256,097 - 541,860 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IQGAP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	70,672,171 - 70,979,766 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	70,672,553 - 70,979,763 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	19,502,207 - 19,811,126 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Iqgap2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624869	889,091 - 1,171,983 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624869	888,868 - 1,172,747 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in IQGAP2
12905 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3


RefSeq Transcripts	XM_021084462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK235549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK236445	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK347952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU856323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU914338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU915424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU928525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP312796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GACC01000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01022400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000015388 ⟹ ENSSSCP00000014979

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	85,294,530 - 85,633,640 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000015389 ⟹ ENSSSCP00000014980

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	85,294,530 - 85,626,032 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000031424 ⟹ ENSSSCP00000028043

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	85,380,901 - 85,624,747 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000098109 ⟹ ENSSSCP00000081090

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	85,523,156 - 85,633,642 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000102076 ⟹ ENSSSCP00000074833

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	85,523,077 - 85,633,642 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000105979 ⟹ ENSSSCP00000080446

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	85,294,530 - 85,633,640 (+)	Ensembl

RefSeq Acc Id:

XM_021084462 ⟹ XP_020940121

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	2	85,294,423 - 85,633,645 (+)	NCBI

Sequence:

show sequence

CGCGCGCTCCCACCGCGGTGGATAACGGGGCCGGGCTGGAGGAGAAAGGAAACCTGTCCGGGAGGCGGCGGCGGCGGCAGCCGGGAGCAAGCGAGGGAGGAGAGTTCACTTTTGCTCGGGTGTCAGCG
CGCGGCGGCCGCAGCGGGCGCTGACGAGGGAACACCGAGAGAGCGGGGCGCCCAACTCGGGGCGGCCAGCGAGAAGCCGGATACGAGCGCGCCGGCGGGGCGCGGAGCGGCGAGCCTGGCTAGCGAGG
GGAGCCGCGGGGGGCGCGCCCCGGGCGGGCCCCCGGAGCTGCGTAGGATGCCCCACGAGGAGCAGGCGTCCCTGCAGAGACCCCGCTATGGCTCTATCGTGGACGATGAAAGACTCTCCGCAGAGGAG
ATGGATGAGAGGAGGCGGCAGAATATCGCTTATGAATATTTGTGCCACCTGGAGGAAGCCAAGAGGTGGATGGAAGTCTGCTTAGTTGAAGAATTGCCGCCAACCACTGAACTGGAAGAAGGGCTTCG
GAACGGCGTTTACCTTGCAAAGTTAGCCAAGTTCTTTGCCCCCAAAATGGTATCGGAGAAAAAGATCTATGATGTGGAGCAAACACGTTATAAGAAATCGGGCCTTCACTTTCGACACACAGATAACA
CCGTCCAGTGGCTGAGAGCGATGGAGTCTATTGGTCTACCCAAGATATTTTACCCAGAAACAACAGATGTGTATGACCGGAAAAACATACCAAGAATGATATATTGCATTCACGCACTAAGTTTGTAT
CTGTTCAAACTAGGAATCGCCCCCCAGATCCAGGATTTGTTGGGCAAAGTAGACTTCACAGAGGAGGAAATCAGTAATATGAGAAAGGAGCTTGAGAAATATGGAATACAGATGCCATCTTTCAGCAA
AATAGGTGGTATTCTGGCTAATGAACTGTCTGTGGATGAAGCTGCTTTGCATGCTGCAGTTATAGCCATTAATGAAGCTATTGAAAAAGGAATAGCAGAGCAGACCATTGTAACGCTAAGAAACCCAA
ATGCAGTTCTCACTTCAGTGGATGACAGCCTTGCACAGGAATATCAGAAGGAACTCTGGGAAGCCAAAAAGAGAAAAGAGGAAAATGCAAGGCTGAAGAATAACTGTATTTCAGAAGAAGAAAGAGAT
GCATATGAAGAATTGCTGACACAAGCAGAAATCCAAGGCCACATTAATAAAGTCAACAGGCTGGCTGCGGTGGACCACATCAACACTGTCCTTCGGGAAGGTGACCCTGAGAACACGCTGCTTGCCCT
GCAGAAACCAGAGGCCCAGCTGCCCACTGTTTATCCCTTTGCTGCTCCAATGTATCAGAACGAGCTTTTCAACCTCCAGAAACAGAACGCCATGAACTATTTGCCCCACGAGGAGCTCGTAATTGCAG
TGGAAATGCTCTCTGCTGTTGCTTTACTAAACCAAGCCTTGGAAAGCAATGACCTTGTGTCTGTGCAGAATCAACTCAGAAGCCCAACAATGGGCTTCAACAATCTGGACGAGATGCATGTGGAACGT
TACGCAAATGCACTTCTCTCCATTAAACTGGAAGCCTTATCCCAAGGGCAAGAGAACTTAAGCTGGAATGAAATTCAGAACTGTATCGATATGGTTAATACTGAAATTCAAGAAGAAAATGACCGAGT
TGTAGCTGTAGGGTACATCAATGAAGCCATTGATGAAGGGGATGCTTTGAAAACCTTAGATAGTCTGCTGTTACCTACTGCAAAGATTAAAGATATAGACCCAGACTCTGCCCAGCACTACCAGGATG
TTTTATACCATGCTAAATCACAGAAGTTCCTGGACCCTCACAGCGCTTCCAAAATTCTGTGGCTGGATGAGATACAGCATGCAGTCAATGAGGCCAACAAGGACAAGGACAAAGCAAAACAATGGGTC
ACACTGGTCGTTGACGTTAATCAGTTTTTGGAGAAGGAGAAGCAAAGTGACATTTTGTCTGTTTTGAAGTCTGCTGTTCCTAATACAAATGACATCATCCCTGAATGTGCCGACAGGTACTATGATGC
CCTGGTGAAGGCAAAAGACCAAAAATCTAACGGTGTGTCTGCTGAAGGTTCATGGCTCAAACTCACCCTGCAGGACAAATACGATTACTACTACAACATCGATTCACAAGAGAGTTCCTGGGTCCCAC
CTGAATCCTTCCTACCTAAAGAATCATGGCTCACAGGAAAAGAAATTAAGGACATTATTGAGGAAATCACAGCAGACTACATCCGTGAGAAGATGTGGTCTGCTCCTGAAGATATGCTTCTTCGCTTT
CAAGCCACAAGCTCAGGACCCCGTCTTAGGAAAGAGTTTGAAGCTAGGAAAGCATTTTTGTACGATCAAGAAGAGCATGTGGTCAAAATACAGGCTTTTTGGAAGGGACATCAGCAACGGGCATCATA
TATGAAGCGGCGACAAATGTTCATTGATAATATTTCAGCAATTGTGAAGATTCAGTCCTGGTTCCGGATGAGAAGAGCACGAAAGAATTACCTTTCACGACTGCAGTATTTCAAAGACCATAACAATG
AAATTGTGAAAATACAGTCTCTCTTGAGAGCAAACAAAGCCAGAGATGACTACAAAACCCTGGTTGGCTCCGAAAACCCACCCTTAACCGTCATCCGCAAGTTCGTACACCTGTTGGATCAAAGCGAC
TTGGATTTCCAGGAGGAGCTGGAGGTGGCGCGATTAAGGGAAGAAGTGGTGACCAAGATCCGGGGCAATCAACAGCTCGAGAAAGACCTGAACCTGATGGACATTAAGATTGGGCTCCTGGTGAAGAA
CAGGATCACGCTGGAGGATGTAATTTCACACAGAACGAAACTGAATAAGAAAAAAGGCGGAGAAATGGAAATACTGAATAGCACTGACAACCAGGGAATTAAAAGTTTGAGTAAAGAGCGGAGGAAAA
CACTGGAAACATATCAGCAGCTTTTTTATCTTTTACAGACCAATCCTTTATACCTGGCTAAGCTGATTTTCCAGATGCCGCAGAACAAGTCAACTAAGTTTATGGATACTGTTATTTTCACATTATAC
AACTATGCTTCCAATCAGCGAGAAGAGTATCTACTCCTCAAGCTTTTTAAAACTGCTCTGGAAGAAGAAATAAAATCAAAGGTGGACCAGGTCCAGGATATAGTTACCGGGAACCCCACAGTCATCAA
GATGGTCGTCAGCTTCAACAGAGGTGCCCGTGGGCAGAACACGCTGCGCCAGCTCCTGGCTCCGGTGGTGAAAGAGATCATTGATGACAAGTCCCTGATGATCAACACGAGCCCCGTCGAGGTCTACA
AGGCCTGGGTCAACCAGCTTGAAACGCAGACTGGAGAAGCCAGCAACCTGCCTTATGATGTGACCACAGAACAAGCTCTGACCTACCCCGAGGTGAAAAACAAACTGGAGGCTTCCATTGAGAACCTG
AGAAGGGTCACCGACAAAGTCCTAAATTCCATCATTTCCTCGCTTGATCTACTGCCTTATGGATTGAGGTATATAGCCAAAGTACTGAAGAATTCGATCCATGAGAAATTTCCTGATGCAACAGAGGA
TGAGCTCTTAAAGATTGTTGGGAACCTCCTGTACTATCGGTACATGAACCCAGCCATCGTAGCTCCAGATGGCTTTGATATCATCGACATGACAGCGGGAGGGCAGATAAATTCCGACCAGAGGAGAA
ACTTGGGATCAGTGGCCAAAGTTCTTCAGCATGCAGCCTCCAACAAGCTCTTTGAAGGAGAAAATGAGCATCTCGCATCTATGAACAATTATTTGTCAGAGACATATCAGGAGTTCAGGAAATATTTC
AAAGAAGCATGCAATGTCCCTGAACCCGAAGAAAAGTTTAATATGGATAAATACACCGATGTGGTGACCGTCAGCAAACCAGTCATTTACATTTCAATTGAAGAGATCATTAGTACACATTCGCTCCT
GTTGGAACACCAGGATGCAATTGCACCAGAAAAAACTGACTTACTGAATGAACTATTAGAATTGCTTGGAGAGGTGCCTAATGTGGAATCTTTTCTTGGGGAAGGAGCTGTTGACCCCAATGATCCTG
ACAGGGTAAACACACTGAATCAACTCTCCAAGACTGAAATTTCCCTTTCCTTGACAAGCAAGTACGACATAGGGGATGGTGAAGCTATTGACGGCCAAAGCCTCATGATCAAGACCAAAAAACTGATC
ATTGATGTGATTCGGAACCAACCAGGGAGCACACTGACAGAGATCTTAGAGACACCAGCTACTACAAAACAGGAGGCCGATCATGCCGCAGACATGGTGAGCCGTGCGATTTTAGATTCCAGGACCCC
TGAGGACTTGAAGCATAGCCAGTCTGTGGTGGAAGATGCACAGCTGCCTCTTGAGCAGAAGAAGAGGAAAATCCAGAGGAATCTTCGGACATTGGAACAGACAGGACATGTGTCATCCAAAAACAAAT
ACCAGGACATTCTCAATGCAATGGCCAAGGATATTCGAAATCAAAGAATCCATCGTAAGCTTCGAAAAGCTGAATTGGCAAAACTTCAGCAGACCCTGAATGCACTTAATAAGAAGGCAGCATTCTTT
GAAGAGCAAATTAATTATTATGATACCTACATAAAGACTTGTTTAGACAACTTAAAAAGAAAAAATTCTCGGAGATCAATTAAACTCGATGGAAAAGGAGAACCCAAAGGGGCAAGGCGAGCAAAGCC
GGTGCGGTACACGGCCGCAAAGCTGCATGAGAAGGGTGTCCTTCTGGACATAGACGATCTTCAGACAAACCAGTTTAAAAATGTTACATTTGATATCTCATCTACTGAAGATGTGGGCATCNTTGATG
TCAGATCGAAATTCCTGGGTGTTGATATGGAAAAGGTGCAGCTCAATATTCAGGATTTACTTCAGATGCAGTATGAAGGAGTAGCTGTAATGAAAATGTTTGATAAGGTTAAAGTGAACGTAAACCTT
CTCATATACCTGCTCAACAAGAAATTCTATGGGAAGTGAAGTGCCTGCAGAAACCTCCTGGATCTCTATCACCTGGATTGGGAAATGAATCTGTTTAGTATTTTTGTTTTTAAACATGATTGAAATCA
CTACTTATACACGCGTGATTCTTTTTTTTTTTTTTAAAGACCAAAACTGTTCCGAAGAATGTACCCATGTGCCTTTTTGATCATCTGAAACTGCAGTAGAATGATACACAAAATGAATTAATGCAAAC
ACTGCCACATTGTACTGTGGTATAGGTACTCTGATTTCCAACTCTGGACATTCTGTGATTTGTTTTAAAGGAGGGGGGAAATAACTTTAGCTGACTAGGGACAAAGGGGTAAACCTATTTTCCTATGA
AAAATAATTTTTTAATGTCCCATTTGAATAATGTACCTCTTCATAGATTTTTTAATCTGTGGAGAAATGGAAACTGAGTTATTTGTAATGAATTATTTAGACAGTTCTCAGCCCTGCCTTCTGAGCGT
TAGCGATTTTAAAAGAGAACTTTTGTGCAATTCAAAATGAAGTTTTTATAAGTAATTGAAAGTGACAATACAGGAACACTTTCTGTATAAAAGTATATATTTTATGTGATTTATTCCTCCTAAATGAA
GTGCACTACTGCCTCGTGGTAAAGACTCTCGGACCCAGAGCCTTTAAGTGACTAGGGAACAACATAAGCAGTGATCATAGGCCTGGATCTCCACCCCTCACAATTTATTTGAATATTTCAATTGTGCC
TCTCAATTTTTTGTAATGCAATAAAATCAGTATCTGGATGGTTTTTAAATGTATTCTTTGAAAAAATTGTTTTATGTAAAATAAATGTTGCTGAATTACA

hide sequence


Protein RefSeqs	XP_020940121	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000014979
	ENSSSCP00000014979.5
	ENSSSCP00000014980.5
	ENSSSCP00000028043.3
	ENSSSCP00000074833.1
	ENSSSCP00000080446.1
	ENSSSCP00000081090.1
	ENSSSCP00030032130.1
	ENSSSCP00030032159.1
	ENSSSCP00030032184.1
	ENSSSCP00030032197.1
	ENSSSCP00030032210.1
	ENSSSCP00035019316.1
	ENSSSCP00035019325.1
	ENSSSCP00035019330.1
	ENSSSCP00035019337.1
	ENSSSCP00040038223.1
	ENSSSCP00040038398.1
	ENSSSCP00045000571.1
	ENSSSCP00045000588.1
	ENSSSCP00045000604.1
	ENSSSCP00055007315.1
	ENSSSCP00055007323.1
	ENSSSCP00055007331.1
	ENSSSCP00065047935.1
	ENSSSCP00065047966.1
GenBank Protein	JAA53789	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_020940121 ⟸ XM_021084462

- UniProtKB:

A0A8D1CT97 (UniProtKB/TrEMBL), A0A8W4FQ33 (UniProtKB/TrEMBL), K9J6M1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPHEEQASLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMESIGLPKI
FYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAVIAINEAIEKGIAEQTIVTLRNPNAVLTSVDDSLAQEYQ
KELWEAKKRKEENARLKNNCISEEERDAYEELLTQAEIQGHINKVNRLAAVDHINTVLREGDPENTLLALQKPEAQLPTVYPFAAPMYQNELFNLQKQNAMNYLPHEELVIAVEMLSAVALLNQALES
NDLVSVQNQLRSPTMGFNNLDEMHVERYANALLSIKLEALSQGQENLSWNEIQNCIDMVNTEIQEENDRVVAVGYINEAIDEGDALKTLDSLLLPTAKIKDIDPDSAQHYQDVLYHAKSQKFLDPHSA
SKILWLDEIQHAVNEANKDKDKAKQWVTLVVDVNQFLEKEKQSDILSVLKSAVPNTNDIIPECADRYYDALVKAKDQKSNGVSAEGSWLKLTLQDKYDYYYNIDSQESSWVPPESFLPKESWLTGKEI
KDIIEEITADYIREKMWSAPEDMLLRFQATSSGPRLRKEFEARKAFLYDQEEHVVKIQAFWKGHQQRASYMKRRQMFIDNISAIVKIQSWFRMRRARKNYLSRLQYFKDHNNEIVKIQSLLRANKARD
DYKTLVGSENPPLTVIRKFVHLLDQSDLDFQEELEVARLREEVVTKIRGNQQLEKDLNLMDIKIGLLVKNRITLEDVISHRTKLNKKKGGEMEILNSTDNQGIKSLSKERRKTLETYQQLFYLLQTNP
LYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLMINTSPVEVYKAWVNQLETQTGEASN
LPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGSVAKVLQHAASNK
LFEGENEHLASMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDVVTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKTDLLNELLELLGEVPNVESFLGEGAVDPNDPDRVNTLNQLSKTEISL
SLTSKYDIGDGEAIDGQSLMIKTKKLIIDVIRNQPGSTLTEILETPATTKQEADHAADMVSRAILDSRTPEDLKHSQSVVEDAQLPLEQKKRKIQRNLRTLEQTGHVSSKNKYQDILNAMAKDIRNQR
IHRKLRKAELAKLQQTLNALNKKAAFFEEQINYYDTYIKTCLDNLKRKNSRRSIKLDGKGEPKGARRAKPVRYTAAKLHEKGVLLDIDDLQTNQFKNVTFDISSTEDVGIXDVRSKFLGVDMEKVQLN
IQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK

hide sequence

Ensembl Acc Id:

ENSSSCP00000014979 ⟸ ENSSSCT00000015388

Ensembl Acc Id:

ENSSSCP00000014980 ⟸ ENSSSCT00000015389

Ensembl Acc Id:

ENSSSCP00000028043 ⟸ ENSSSCT00000031424

Ensembl Acc Id:

ENSSSCP00000081090 ⟸ ENSSSCT00000098109

Protein Domains

Calponin-homology (CH) Ras-GAP WW

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000014088	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00030050463	UniProtKB/TrEMBL
	ENSSSCG00035036426	UniProtKB/TrEMBL
	ENSSSCG00040063703	UniProtKB/TrEMBL
	ENSSSCG00045000703	UniProtKB/TrEMBL
	ENSSSCG00055004674	UniProtKB/TrEMBL
	ENSSSCG00065077652	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000015388	ENTREZGENE
	ENSSSCT00000015388.5	UniProtKB/TrEMBL
	ENSSSCT00000015389.5	UniProtKB/TrEMBL
	ENSSSCT00000031424.4	UniProtKB/TrEMBL
	ENSSSCT00000098109.1	UniProtKB/TrEMBL
	ENSSSCT00000102076.1	UniProtKB/TrEMBL
	ENSSSCT00000105979.1	UniProtKB/TrEMBL
	ENSSSCT00030070445.1	UniProtKB/TrEMBL
	ENSSSCT00030070503.1	UniProtKB/TrEMBL
	ENSSSCT00030070544.1	UniProtKB/TrEMBL
	ENSSSCT00030070569.1	UniProtKB/TrEMBL
	ENSSSCT00030070599.1	UniProtKB/TrEMBL
	ENSSSCT00035048299.1	UniProtKB/TrEMBL
	ENSSSCT00035048319.1	UniProtKB/TrEMBL
	ENSSSCT00035048331.1	UniProtKB/TrEMBL
	ENSSSCT00035048348.1	UniProtKB/TrEMBL
	ENSSSCT00040087057.1	UniProtKB/TrEMBL
	ENSSSCT00040087411.1	UniProtKB/TrEMBL
	ENSSSCT00045001043.1	UniProtKB/TrEMBL
	ENSSSCT00045001070.1	UniProtKB/TrEMBL
	ENSSSCT00045001094.1	UniProtKB/TrEMBL
	ENSSSCT00055009226.1	UniProtKB/TrEMBL
	ENSSSCT00055009234.1	UniProtKB/TrEMBL
	ENSSSCT00055009242.1	UniProtKB/TrEMBL
	ENSSSCT00065107492.1	UniProtKB/TrEMBL
	ENSSSCT00065107561.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.418.10	UniProtKB/TrEMBL
	1.20.5.190	UniProtKB/TrEMBL
	GTPase Activation - p120gap, domain 1	UniProtKB/TrEMBL
InterPro	CH-domain	UniProtKB/TrEMBL
	CH_dom_sf	UniProtKB/TrEMBL
	IQ_motif_EF-hand-BS	UniProtKB/TrEMBL
	RasGAP_C	UniProtKB/TrEMBL
	RasGAP_CS	UniProtKB/TrEMBL
	RasGAP_dom	UniProtKB/TrEMBL
	Rho_GTPase_activation_prot	UniProtKB/TrEMBL
	WW_dom	UniProtKB/TrEMBL
NCBI Gene	IQGAP2	ENTREZGENE
PANTHER	RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF	UniProtKB/TrEMBL
	RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2	UniProtKB/TrEMBL
Pfam	PF00307	UniProtKB/TrEMBL
	PF00612	UniProtKB/TrEMBL
	RasGAP	UniProtKB/TrEMBL
	RasGAP_C	UniProtKB/TrEMBL
PROSITE	PS50021	UniProtKB/TrEMBL
	PS50096	UniProtKB/TrEMBL
	RAS_GTPASE_ACTIV_1	UniProtKB/TrEMBL
	RAS_GTPASE_ACTIV_2	UniProtKB/TrEMBL
	WW_DOMAIN_1	UniProtKB/TrEMBL
	WW_DOMAIN_2	UniProtKB/TrEMBL
SMART	RasGAP	UniProtKB/TrEMBL
	SM00015	UniProtKB/TrEMBL
	SM00033	UniProtKB/TrEMBL
Superfamily-SCOP	RGC domain-like	UniProtKB/TrEMBL
	SSF47576	UniProtKB/TrEMBL
	SSF48350	UniProtKB/TrEMBL
UniProt	A0A8D0X480_PIG	UniProtKB/TrEMBL
	A0A8D0X7D5_PIG	UniProtKB/TrEMBL
	A0A8D0X7U9_PIG	UniProtKB/TrEMBL
	A0A8D0X935_PIG	UniProtKB/TrEMBL
	A0A8D0ZJR4_PIG	UniProtKB/TrEMBL
	A0A8D0ZJW8_PIG	UniProtKB/TrEMBL
	A0A8D1CT97	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1G7S1_PIG	UniProtKB/TrEMBL
	A0A8D1GB44_PIG	UniProtKB/TrEMBL
	A0A8D1GDZ5_PIG	UniProtKB/TrEMBL
	A0A8D1PJG3_PIG	UniProtKB/TrEMBL
	A0A8D1PKF3_PIG	UniProtKB/TrEMBL
	A0A8D1PQQ9_PIG	UniProtKB/TrEMBL
	A0A8D2A983_PIG	UniProtKB/TrEMBL
	A0A8D2AAF2_PIG	UniProtKB/TrEMBL
	A0A8W4F7T1_PIG	UniProtKB/TrEMBL
	A0A8W4FNZ9_PIG	UniProtKB/TrEMBL
	A0A8W4FQ33	ENTREZGENE, UniProtKB/TrEMBL
	F1S2H7_PIG	UniProtKB/TrEMBL
	F1S2H8_PIG	UniProtKB/TrEMBL
	I3LV91_PIG	UniProtKB/TrEMBL
	K9J6M1	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:89192	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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