SEMA5A (semaphorin 5A) - Rat Genome Database

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Gene: SEMA5A (semaphorin 5A) Sus scrofa
Analyze
Symbol: SEMA5A
Name: semaphorin 5A
RGD ID: 14089040
Description: ENCODES a protein that exhibits axon guidance receptor activity (ortholog); chondroitin sulfate proteoglycan binding (ortholog); heparan sulfate proteoglycan binding (ortholog); INVOLVED IN axon extension (ortholog); axon guidance (ortholog); axonal fasciculation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Charcot-Marie-Tooth disease (ortholog); intellectual disability (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: semaphorin-5A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1672,756,383 - 73,328,981 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11672,796,453 - 73,335,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21678,742,131 - 79,220,468 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SEMA5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1672,756,383 - 73,328,981 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11672,796,453 - 73,335,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21678,742,131 - 79,220,468 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEMA5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3859,035,033 - 9,546,075 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl59,035,033 - 9,546,075 (-)EnsemblGRCh38hg38GRCh38
GRCh3759,035,145 - 9,546,187 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3659,088,138 - 9,599,233 (-)NCBINCBI36Build 36hg18NCBI36
Build 3459,091,858 - 9,599,158NCBI
Celera59,075,672 - 9,586,506 (-)NCBICelera
Cytogenetic Map5p15.31NCBI
HuRef59,020,618 - 9,529,962 (-)NCBIHuRef
CHM1_159,034,070 - 9,546,215 (-)NCBICHM1_1
T2T-CHM13v2.058,974,898 - 9,485,916 (-)NCBIT2T-CHM13v2.0
Sema5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391532,244,959 - 32,696,487 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1532,244,956 - 32,696,487 (+)EnsemblGRCm39 Ensembl
GRCm381532,244,813 - 32,696,341 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1532,244,810 - 32,696,341 (+)EnsemblGRCm38mm10GRCm38
MGSCv371532,174,568 - 32,626,096 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361532,361,948 - 32,640,922 (+)NCBIMGSCv36mm8
Celera1532,949,262 - 33,396,657 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1513.02NCBI
Sema5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8285,020,724 - 85,451,938 (+)NCBIGRCr8
mRatBN7.2283,309,843 - 83,741,084 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl283,309,843 - 83,741,084 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx290,354,073 - 90,791,652 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0288,475,679 - 88,913,259 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0283,531,943 - 83,969,519 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0285,377,318 - 85,808,970 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl285,377,318 - 85,808,970 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02105,049,343 - 105,480,370 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4284,725,092 - 85,158,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1284,835,136 - 85,097,066 (+)NCBI
Celera278,800,990 - 79,231,054 (+)NCBICelera
Cytogenetic Map2q23NCBI
Sema5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555046,350,866 - 6,762,104 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555046,343,747 - 6,691,945 (-)NCBIChiLan1.0ChiLan1.0
SEMA5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v249,272,092 - 9,780,658 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan157,425,701 - 7,935,102 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v059,349,473 - 9,852,183 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.159,168,549 - 9,672,779 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl59,168,549 - 9,564,356 (-)Ensemblpanpan1.1panPan2
SEMA5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1344,612,202 - 5,089,071 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl344,612,142 - 5,082,280 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha349,122,860 - 9,593,613 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0344,522,038 - 4,992,481 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl344,521,503 - 4,998,657 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1344,573,215 - 5,048,444 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0344,553,933 - 5,029,831 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0344,776,835 - 5,250,400 (+)NCBIUU_Cfam_GSD_1.0
Sema5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213237,599,219 - 238,050,371 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366431,355,070 - 1,637,151 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366431,352,401 - 1,803,553 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.148,598,680 - 9,095,346 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl48,600,959 - 9,095,423 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606419,470,071 - 19,975,962 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247516,436,854 - 6,738,216 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247516,429,814 - 6,913,673 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SEMA5A
28365 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000018613   ⟹   ENSSSCP00000018112
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1672,492,516 - 73,271,224 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000069586   ⟹   ENSSSCP00000060337
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1672,756,383 - 73,328,981 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000088383   ⟹   ENSSSCP00000069246
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1672,492,516 - 73,188,600 (+)Ensembl
RefSeq Acc Id: XM_021076851   ⟹   XP_020932510
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11672,796,453 - 73,335,974 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020932510 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000060337
  ENSSSCP00000060337.1
  ENSSSCP00060001495.1
RefSeq Acc Id: XP_020932510   ⟸   XM_021076851
- UniProtKB: A0A5G2QPX3 (UniProtKB/TrEMBL),   A0A8D1SIV4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000069246   ⟸   ENSSSCT00000088383
Ensembl Acc Id: ENSSSCP00000060337   ⟸   ENSSSCT00000069586
Ensembl Acc Id: ENSSSCP00000018112   ⟸   ENSSSCT00000018613
Protein Domains
Sema


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017095 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00060003602 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000069586 ENTREZGENE
  ENSSSCT00000069586.2 UniProtKB/TrEMBL
  ENSSSCT00060004462.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.20.100.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Plexin_repeat UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema5A_sema UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene SEMA5A ENTREZGENE
PANTHER PTHR11036 UniProtKB/TrEMBL
  SEMAPHORIN-5A UniProtKB/TrEMBL
Pfam PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS TSP1REPEAT UniProtKB/TrEMBL
PROSITE SEMA UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A5G2QPX3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SIV4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92706 ENTREZGENE