VENTX (VENT homeobox) - Rat Genome Database

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Gene: VENTX (VENT homeobox) Sus scrofa
Analyze
Symbol: VENTX
Name: VENT homeobox
RGD ID: 14064207
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH distal 10q deletion syndrome (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein VENTX
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.114141,265,966 - 141,271,379 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214153,230,251 - 153,234,337 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VENTXPigdistal 10q deletion syndrome  ISOVENTX (Homo sapiens)8554872ClinVar Annotator: match by term: Distal 10q deletion syndromeClinVarPMID:31690835
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VENTXPigesophagus squamous cell carcinoma  ISOVENTX (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:30431698


Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VENTXPignucleus located_inIEAUniRule:UR000401037150520179 UniProtGO_REF:0000104
VENTXPignucleus located_inIEAUniProtKB:P70354 and ensembl:ENSMUSP00000133484150520179 EnsemblGO_REF:0000107
VENTXPignucleus is_active_inIBAFB:FBgn0000492 more ...150520179 GO_CentralGO_REF:0000033
VENTXPignucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
VENTXPignucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
VENTXPigDNA binding enablesIEAUniProtKB-KW:KW-0238 and UniProtKB-KW:KW-0371150520179 UniProtGO_REF:0000043
VENTXPigDNA binding enablesIEAInterPro:IPR001356 and InterPro:IPR020479150520179 InterProGO_REF:0000002
VENTXPigDNA binding enablesIEAUniRule:UR000401037150520179 UniProtGO_REF:0000104
VENTXPigDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOVENTX (Homo sapiens)9068941 PMID:21325273NTNU_SBPMID:21325273
VENTXPigDNA-binding transcription factor activity, RNA polymerase II-specific enablesIEAInterPro:IPR017970150520179 InterProGO_REF:0000002
VENTXPigDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAMGI:97168 more ...150520179 GO_CentralGO_REF:0000033
VENTXPighistone acetyltransferase binding enablesIEAUniProtKB:P70354 and ensembl:ENSMUSP00000133484150520179 EnsemblGO_REF:0000107
VENTXPighistone acetyltransferase regulator activity enablesIEAUniProtKB:P70354 and ensembl:ENSMUSP00000133484150520179 EnsemblGO_REF:0000107
VENTXPigprotein binding enablesISOUniProtKB:A0A0C4DGF1 more ...9068941 PMID:32296183IntActPMID:32296183
VENTXPigprotein binding enablesISOPR:O890909068941 PMID:1909605MGIPMID:1909605
VENTXPigprotein binding enablesISOUniProtKB:O75553 more ...9068941 PMID:31515488IntActPMID:31515488
VENTXPigprotein binding enablesISOUniProtKB:O75553 more ...9068941 PMID:25416956IntActPMID:25416956
VENTXPigRNA polymerase II transcription regulatory region sequence-specific DNA binding enablesIBAMGI:97168 more ...150520179 GO_CentralGO_REF:0000033
VENTXPigsequence-specific DNA binding enablesISOVENTX (Homo sapiens)9068941 PMID:23332764NTNU_SBPMID:23332764
VENTXPigsequence-specific double-stranded DNA binding enablesISOVENTX (Homo sapiens)9068941 PMID:28473536ARUK-UCLPMID:28473536
1 to 15 of 15 rows

PMID:22301074   PMID:30032202  



VENTX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.114141,265,966 - 141,271,379 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214153,230,251 - 153,234,337 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VENTX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810133,237,855 - 133,241,928 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10133,237,855 - 133,241,928 (+)EnsemblGRCh38hg38GRCh38
GRCh3710135,051,359 - 135,055,432 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610134,901,398 - 134,905,423 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410134,940,288 - 134,944,314NCBI
Celera10128,461,096 - 128,465,122 (-)NCBICelera
Cytogenetic Map10q26.3NCBI
HuRef10128,597,892 - 128,601,917 (+)NCBIHuRef
CHM1_110135,332,231 - 135,337,304 (+)NCBICHM1_1
T2T-CHM13v2.010134,193,345 - 134,197,419 (+)NCBIT2T-CHM13v2.0
Msx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397139,626,070 - 139,629,001 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7139,626,070 - 139,629,002 (-)EnsemblGRCm39 Ensembl
GRCm387140,046,157 - 140,049,088 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7140,046,157 - 140,049,089 (-)EnsemblGRCm38mm10GRCm38
MGSCv377147,232,056 - 147,234,987 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367139,897,582 - 139,900,409 (-)NCBIMGSCv36mm8
Celera7139,844,251 - 139,847,182 (-)NCBICelera
Cytogenetic Map7F4NCBI
cM Map785.04NCBI
Ventx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X90,707,273 - 90,708,315 (-)NCBIGRCr8
mRatBN7.2X86,483,893 - 86,484,900 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX86,483,893 - 86,484,954 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X93,064,417 - 93,067,181 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX93,064,686 - 93,065,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X92,964,258 - 92,966,244 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X110,278,093 - 110,284,738 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX87,622,250 - 87,623,796 (-)NCBICelera
Cytogenetic MapXq31NCBI
Ventx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547710,945,539 - 10,948,735 (-)NCBIChiLan1.0ChiLan1.0
VENTX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28145,358,390 - 145,361,771 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110145,363,746 - 145,367,128 (+)NCBINHGRI_mPanPan1
PanPan1.110134,144,329 - 134,149,277 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10134,144,411 - 134,149,277 (+)Ensemblpanpan1.1panPan2
VENTX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12840,836,688 - 40,840,145 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2840,836,403 - 40,840,127 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2840,892,938 - 40,896,442 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02841,474,254 - 41,477,565 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2841,474,254 - 41,477,129 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12840,956,347 - 40,960,315 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02840,946,496 - 40,949,807 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02841,349,114 - 41,352,425 (+)NCBIUU_Cfam_GSD_1.0
Ventx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244072136,121,855 - 6,135,914 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648619,434,362 - 19,436,025 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VENTX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604887,601,609 - 87,604,034 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ventx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473713,415,558 - 13,416,906 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in VENTX
106 total Variants



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 22 3 2 5 14 12 22 3 5 3



RefSeq Acc Id: XM_013994455   ⟹   XP_013849909
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114141,265,966 - 141,271,379 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021073937   ⟹   XP_020929596
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114141,265,966 - 141,271,379 (-)NCBI
Sequence:
Protein RefSeqs XP_013849909 (Get FASTA)   NCBI Sequence Viewer  
  XP_020929596 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000039546.3
  ENSSSCP00035044766.1
  ENSSSCP00055008789.1
  ENSSSCP00065045654.1
RefSeq Acc Id: XP_013849909   ⟸   XM_013994455
- Peptide Label: isoform X2
- UniProtKB: A0A8D1TW80 (UniProtKB/TrEMBL),   A0A8D1BG66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020929596   ⟸   XM_021073937
- Peptide Label: isoform X1
- Sequence:
Homeobox



1 to 28 of 28 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000033363 UniProtKB/TrEMBL
  ENSSSCG00035076771 UniProtKB/TrEMBL
  ENSSSCG00055005729 UniProtKB/TrEMBL
  ENSSSCG00065074948 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000054100.3 UniProtKB/TrEMBL
  ENSSSCT00035104454.1 UniProtKB/TrEMBL
  ENSSSCT00055011135.1 UniProtKB/TrEMBL
  ENSSSCT00065103305.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/TrEMBL
  Msh_Homeobox_Regulators UniProtKB/TrEMBL
KEGG Report ssc:100154934 UniProtKB/TrEMBL
NCBI Gene VENTX ENTREZGENE
PANTHER HOMEOBOX PROTEIN MSX UniProtKB/TrEMBL
  HOMEOBOX PROTEIN MSX-3 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PRINTS HOMEOBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A287A6P3_PIG UniProtKB/TrEMBL
  A0A8D1BG66 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1TW80 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480JLL2 UniProtKB/TrEMBL
1 to 28 of 28 rows