TPR (translocated promoter region, nuclear basket protein) - Rat Genome Database

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Gene: TPR (translocated promoter region, nuclear basket protein) Sus scrofa
Analyze
Symbol: TPR
Name: translocated promoter region, nuclear basket protein
RGD ID: 14053487
Description: ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN nuclear matrix organization (ortholog); nuclear pore complex assembly (ortholog); nuclear pore organization (ortholog); ASSOCIATED WITH Autosomal Recessive Intellectual Developmental Disorder 79 (ortholog); camptodactyly-arthropathy-coxa vara-pericarditis syndrome (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN kinetochore (ortholog); nuclear envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nucleoprotein TPR; translocated promoter region (to activated MET oncogene)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9127,481,684 - 127,540,398 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19127,481,678 - 127,540,393 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29139,933,094 - 139,992,501 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TPR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9127,481,684 - 127,540,398 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19127,481,678 - 127,540,393 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29139,933,094 - 139,992,501 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TPR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381186,311,652 - 186,375,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1186,311,652 - 186,375,693 (-)EnsemblGRCh38hg38GRCh38
GRCh371186,280,784 - 186,344,385 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361184,547,407 - 184,611,080 (-)NCBINCBI36Build 36hg18NCBI36
Build 341183,014,615 - 183,076,114NCBI
Celera1159,391,490 - 159,455,165 (-)NCBICelera
Cytogenetic Map1q31.1NCBI
HuRef1157,515,355 - 157,578,976 (-)NCBIHuRef
CHM1_11187,702,490 - 187,766,196 (-)NCBICHM1_1
T2T-CHM13v2.01185,666,310 - 185,729,984 (-)NCBIT2T-CHM13v2.0
Tpr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,268,544 - 150,325,686 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,268,589 - 150,325,686 (+)EnsemblGRCm39 Ensembl
GRCm381150,392,802 - 150,449,935 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,392,838 - 150,449,935 (+)EnsemblGRCm38mm10GRCm38
MGSCv371152,239,968 - 152,297,065 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361152,155,071 - 152,212,147 (+)NCBIMGSCv36mm8
Celera1152,832,018 - 152,889,087 (+)NCBICelera
Cytogenetic Map1G1NCBI
cM Map163.84NCBI
Tpr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81364,974,419 - 65,037,604 (+)NCBIGRCr8
mRatBN7.21362,424,312 - 62,487,502 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1362,424,312 - 62,487,496 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1365,070,740 - 65,133,881 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01366,341,843 - 66,405,114 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01363,603,135 - 63,666,355 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01367,611,685 - 67,672,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1367,611,708 - 67,672,827 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01372,576,506 - 72,637,654 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41364,688,585 - 64,753,555 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11364,702,435 - 64,767,635 (+)NCBI
Celera1362,384,785 - 62,447,122 (+)NCBICelera
Cytogenetic Map13q21NCBI
Tpr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540624,742,525 - 24,805,989 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540624,742,525 - 24,805,989 (-)NCBIChiLan1.0ChiLan1.0
TPR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2163,343,613 - 63,405,202 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1163,025,048 - 63,086,633 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,842,037 - 161,903,567 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11165,993,726 - 166,055,223 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1165,993,726 - 166,055,223 (-)Ensemblpanpan1.1panPan2
TPR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1719,376,951 - 19,442,368 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl719,376,975 - 19,442,303 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha718,898,638 - 18,964,055 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0719,112,960 - 19,178,509 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl719,112,979 - 19,179,044 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1719,019,776 - 19,085,277 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0719,129,102 - 19,194,530 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0719,259,646 - 19,325,389 (-)NCBIUU_Cfam_GSD_1.0
Tpr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934486,203,944 - 86,264,933 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364814,050,794 - 4,111,682 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364814,050,693 - 4,111,682 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12543,056,605 - 43,120,570 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2543,056,886 - 43,123,474 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605544,245,730 - 44,312,643 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248147,249,278 - 7,306,235 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248147,249,379 - 7,306,239 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TPR
2010 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000016969   ⟹   ENSSSCP00000016515
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9127,481,684 - 127,540,375 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000056338   ⟹   ENSSSCP00000031528
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9127,481,684 - 127,540,205 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000099634   ⟹   ENSSSCP00000079483
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9127,522,357 - 127,540,398 (-)Ensembl
RefSeq Acc Id: XM_013977898   ⟹   XP_013833352
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19127,481,678 - 127,540,393 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063816   ⟹   XP_020919475
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19127,481,678 - 127,540,007 (-)NCBI
Sequence:
RefSeq Acc Id: XP_013833352   ⟸   XM_013977898
- Peptide Label: isoform X2
- UniProtKB: A0A4X1TQA9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919475   ⟸   XM_021063816
- Peptide Label: isoform X1
- UniProtKB: F1S300 (UniProtKB/TrEMBL),   A0A8D1MR09 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000016515   ⟸   ENSSSCT00000016969
Ensembl Acc Id: ENSSSCP00000031528   ⟸   ENSSSCT00000056338
Ensembl Acc Id: ENSSSCP00000079483   ⟸   ENSSSCT00000099634
Protein Domains
Nucleoprotein TPR/MLP1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015576 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015029544 UniProtKB/TrEMBL
  ENSSSCG00025066322 UniProtKB/TrEMBL
  ENSSSCG00045038260 UniProtKB/TrEMBL
  ENSSSCG00050046767 UniProtKB/TrEMBL
  ENSSSCG00055027868 UniProtKB/TrEMBL
  ENSSSCG00065003047 UniProtKB/TrEMBL
  ENSSSCG00070011302 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016969.5 UniProtKB/TrEMBL
  ENSSSCT00000056338 ENTREZGENE
  ENSSSCT00000056338.3 UniProtKB/TrEMBL
  ENSSSCT00000099634.1 UniProtKB/TrEMBL
  ENSSSCT00015039460.1 UniProtKB/TrEMBL
  ENSSSCT00015040103.1 UniProtKB/TrEMBL
  ENSSSCT00015040287.1 UniProtKB/TrEMBL
  ENSSSCT00015040440.1 UniProtKB/TrEMBL
  ENSSSCT00015041013.1 UniProtKB/TrEMBL
  ENSSSCT00025091189.1 UniProtKB/TrEMBL
  ENSSSCT00025092179.1 UniProtKB/TrEMBL
  ENSSSCT00045066281.1 UniProtKB/TrEMBL
  ENSSSCT00045066369.1 UniProtKB/TrEMBL
  ENSSSCT00045066473.1 UniProtKB/TrEMBL
  ENSSSCT00050063703.1 UniProtKB/TrEMBL
  ENSSSCT00055055688.1 UniProtKB/TrEMBL
  ENSSSCT00055055936.1 UniProtKB/TrEMBL
  ENSSSCT00065004085.1 UniProtKB/TrEMBL
  ENSSSCT00065004101.1 UniProtKB/TrEMBL
  ENSSSCT00070022234.1 UniProtKB/TrEMBL
  ENSSSCT00070022243.1 UniProtKB/TrEMBL
  ENSSSCT00070022253.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.1490 UniProtKB/TrEMBL
InterPro TPR/MLP1 UniProtKB/TrEMBL
NCBI Gene TPR ENTREZGENE
PANTHER NUCLEOPROTEIN TPR UniProtKB/TrEMBL
  NUCLEOPROTEIN TPR-RELATED UniProtKB/TrEMBL
Pfam TPR_MLP1_2 UniProtKB/TrEMBL
UniProt A0A286ZJ74_PIG UniProtKB/TrEMBL
  A0A4X1TQA9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TT55_PIG UniProtKB/TrEMBL
  A0A8D0JGB5_PIG UniProtKB/TrEMBL
  A0A8D0N9G4_PIG UniProtKB/TrEMBL
  A0A8D0NB14_PIG UniProtKB/TrEMBL
  A0A8D0U0U1_PIG UniProtKB/TrEMBL
  A0A8D1JGX6_PIG UniProtKB/TrEMBL
  A0A8D1JP25_PIG UniProtKB/TrEMBL
  A0A8D1JPI6_PIG UniProtKB/TrEMBL
  A0A8D1MR09 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1X992_PIG UniProtKB/TrEMBL
  A0A8W4FJI0_PIG UniProtKB/TrEMBL
  F1S300 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:108623 ENTREZGENE